{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T03:16:46Z","timestamp":1782962206356,"version":"3.54.5"},"reference-count":38,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajodo.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Orthodontics and Dentofacial Orthopedics"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.ajodo.2017.01.021","type":"journal-article","created":{"date-parts":[[2017,8,30]],"date-time":"2017-08-30T12:52:27Z","timestamp":1504097547000},"page":"382-388","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Genome-wide association study for mandibular prognathism using microsatellite and pooled DNA method"],"prefix":"10.1016","volume":"152","author":[{"given":"Fumio","family":"Saito","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi S.","family":"Kajii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Oka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiichiro","family":"Ikuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junichiro","family":"Iida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajodo.2017.01.021_bib1","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/j.1601-6343.2010.01485.x","article-title":"Genes, genetics, and Class III malocclusion","volume":"13","author":"Xue","year":"2010","journal-title":"Orthod Craniofac Res"},{"issue":"Suppl 1","key":"10.1016\/j.ajodo.2017.01.021_bib2","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/ocr.12083","article-title":"Genetics of the dentofacial variation in human malocclusion","volume":"18","author":"Moreno Uribe","year":"2015","journal-title":"Orthod Craniofac Res"},{"key":"10.1016\/j.ajodo.2017.01.021_bib3","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1177\/154405910508400309","article-title":"Genome-wide linkage analysis of mandibular prognathism in Korean and Japanese patients","volume":"84","author":"Yamaguchi","year":"2005","journal-title":"J Dent Res"},{"key":"10.1016\/j.ajodo.2017.01.021_bib4","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1177\/0022034510375962","article-title":"Polymorphisms in the Matrilin-1 gene and risk of mandibular prognathism in Koreans","volume":"89","author":"Jang","year":"2010","journal-title":"J Dent Res"},{"key":"10.1016\/j.ajodo.2017.01.021_bib5","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/j.archoralbio.2010.07.018","article-title":"Identification of SNP markers on 1p36 and association analysis of EPB41 with mandibular prognathism in a Chinese population","volume":"55","author":"Xue","year":"2010","journal-title":"Arch Oral Biol"},{"key":"10.1016\/j.ajodo.2017.01.021_bib6","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1177\/0022034511416668","article-title":"Exclusion of Class III malocclusion candidate loci in Brazilian families","volume":"90","author":"Cruz","year":"2011","journal-title":"J Dent Res"},{"key":"10.1016\/j.ajodo.2017.01.021_bib7","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1177\/0022034508327817","article-title":"Evidence of linkage in a Hispanic cohort with a Class III dentofacial phenotype","volume":"88","author":"Frazier-Bowers","year":"2009","journal-title":"J Dent Res"},{"key":"10.1016\/j.ajodo.2017.01.021_bib8","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.ajodo.2011.06.033","article-title":"Genetic variation in Myosin 1H contributes to mandibular prognathism","volume":"141","author":"Tassopoulou-Fishell","year":"2012","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"10.1016\/j.ajodo.2017.01.021_bib9","doi-asserted-by":"crossref","first-page":"e12678","DOI":"10.1371\/journal.pone.0012678","article-title":"Genome scan for locus involved in mandibular prognathism in pedigrees from China","volume":"5","author":"Li","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.ajodo.2017.01.021_bib10","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1177\/0022034510382546","article-title":"The identification of a novel locus for mandibular prognathism in the Han Chinese population","volume":"90","author":"Li","year":"2011","journal-title":"J Dent Res"},{"key":"10.1016\/j.ajodo.2017.01.021_bib11","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1126\/science.273.5281.1516","article-title":"The future of genetic studies of complex human diseases","volume":"273","author":"Risch","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.ajodo.2017.01.021_bib12","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/j.1346-8138.2012.01504.x","article-title":"Current understanding of human genetics and genetic analysis of psoriasis","volume":"39","author":"Oka","year":"2012","journal-title":"J Dermatol"},{"key":"10.1016\/j.ajodo.2017.01.021_bib13","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.ajodo.2014.01.022","article-title":"Microsatellite genome-wide association study for mandibular prognathism","volume":"145","author":"Ikuno","year":"2014","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"10.1016\/j.ajodo.2017.01.021_bib14","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1177\/0022034515589957","article-title":"The ADAMTSI gene is associated with familial mandibular prognathism","volume":"94","author":"Guan","year":"2015","journal-title":"J Dent Res"},{"key":"10.1016\/j.ajodo.2017.01.021_bib15","doi-asserted-by":"crossref","first-page":"247","DOI":"10.2485\/jhtb.25.247","article-title":"Craniofacial morphology of Class III malocclusion with DUSP6 gene: mutation and non-mutation groups","volume":"25","author":"Nowrin","year":"2016","journal-title":"J Hard Tissue Biol"},{"key":"10.1016\/j.ajodo.2017.01.021_bib16","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1086\/515512","article-title":"Association mapping of disease loci, by use of a pooled DNA genomic screen","volume":"61","author":"Barcellos","year":"1997","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.ajodo.2017.01.021_bib17","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1007\/s004399900213","article-title":"A simple and accurate method for determination of microsatellite total allele content differences between DNA pools","volume":"106","author":"Collins","year":"2000","journal-title":"Hum Genet"},{"key":"10.1016\/j.ajodo.2017.01.021_bib18","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1034\/j.1399-0039.2003.00007.x","article-title":"Localization of a non-melanoma skin cancer susceptibility region within the major histocompatibility complex by association analysis using microsatellite markers","volume":"61","author":"Oka","year":"2003","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.ajodo.2017.01.021_bib19","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.1093\/hmg\/ddi234","article-title":"Whole genome association study of rheumatoid arthritis using 27,039 microsatellites","volume":"14","author":"Tamiya","year":"2005","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.ajodo.2017.01.021_bib20","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1093\/oxfordjournals.jhered.a111573","article-title":"GENEPOP (version 1.2). Population genetics software for exact tests and and ecumenicism","volume":"86","author":"Raymond","year":"1995","journal-title":"J Hered"},{"key":"10.1016\/j.ajodo.2017.01.021_bib21","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1086\/503751","article-title":"Coverage and power in genome-wide association studies","volume":"78","author":"Jorgenson","year":"2006","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.ajodo.2017.01.021_bib22","first-page":"425","article-title":"Microsatellite markers for linkage and association studies","volume":"4","author":"Gulcher","year":"2012","journal-title":"Cold Spring Harb Protoc"},{"key":"10.1016\/j.ajodo.2017.01.021_bib23","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.jneuroim.2003.08.020","article-title":"A whole genome screen for linkage disequilibrium in multiple sclerosis performed in a continental Italian population","volume":"143","author":"Liguori","year":"2003","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.ajodo.2017.01.021_bib24","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1681\/ASN.2005050493","article-title":"A genome-wide DNA microsatellite association screen to identify chromosomal regions harboring candidate genes in diabetic nephropathy","volume":"17","author":"McKnight","year":"2006","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.ajodo.2017.01.021_bib25","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1086\/505539","article-title":"Genome wide association analysis of human narcolepsy and a new resistance gene","volume":"79","author":"Kawashima","year":"2006","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.ajodo.2017.01.021_bib26","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/s00439-008-0477-9","article-title":"A genome-wide association scan for asthma in a general Australian population","volume":"123","author":"Hui","year":"2008","journal-title":"Hum Genet"},{"key":"10.1016\/j.ajodo.2017.01.021_bib27","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/j.ajhg.2008.03.016","article-title":"Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP","volume":"82","author":"Zhernakova","year":"2008","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.ajodo.2017.01.021_bib28","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1136\/ard.2007.079871","article-title":"Association of the toll-like receptor 4 gene polymorphisms with Behcet\u2019s disease","volume":"67","author":"Meguro","year":"2008","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.ajodo.2017.01.021_bib29","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.bbrc.2011.08.013","article-title":"A novel splicing variant of CADM2 as a protective transcript of psoriasis","volume":"412","author":"Hiruma","year":"2011","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.ajodo.2017.01.021_bib30","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1042\/BST0340846","article-title":"The GAP1 family of GTPase-activating proteins: spatial and temporal regulators of small GTPase signalling","volume":"34","author":"Yarwood","year":"2006","journal-title":"Biochem Soc Trans"},{"key":"10.1016\/j.ajodo.2017.01.021_bib31","doi-asserted-by":"crossref","first-page":"8679","DOI":"10.1007\/s13277-015-3476-1","article-title":"Clinicopathological significance and biological role of TCF21 mRNA in breast cancer","volume":"36","author":"Wang","year":"2015","journal-title":"Tumour Biol"},{"key":"10.1016\/j.ajodo.2017.01.021_bib32","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.neulet.2015.07.001","article-title":"Experimental validation of candidate schizophrenia gene CALN1 as a target for microRNA-137","volume":"602","author":"Xia","year":"2015","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.ajodo.2017.01.021_bib33","doi-asserted-by":"crossref","first-page":"9197","DOI":"10.1073\/pnas.150246097","article-title":"in\u00a0vitro and in\u00a0vivo evidence for orphan nuclear receptor RORalpha function in bone metabolism","volume":"97","author":"Meyer","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.ajodo.2017.01.021_bib34","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/0002-9416(69)90036-0","article-title":"Prediction of mandibular growth rotation","volume":"55","author":"Bj\u00f6rk","year":"1969","journal-title":"Am J Orthod"},{"key":"10.1016\/j.ajodo.2017.01.021_bib35","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1038\/nature08250","article-title":"Targeted capture and massively parallel sequencing of 12 human exomes","volume":"461","author":"Ng","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.ajodo.2017.01.021_bib36","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1177\/0022034513502790","article-title":"A missense mutation in DUSP6 is associated with Class III malocclusion","volume":"92","author":"Nikopensius","year":"2013","journal-title":"J Dent Res"},{"key":"10.1016\/j.ajodo.2017.01.021_bib37","doi-asserted-by":"crossref","first-page":"11250","DOI":"10.1038\/srep11250","article-title":"Identification of a mutation in FGF23 involved in mandibular prognathism","volume":"5","author":"Chen","year":"2015","journal-title":"Sci Rep"},{"key":"10.1016\/j.ajodo.2017.01.021_bib38","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1177\/0022034515572190","article-title":"Genetic association of ARHGAP21 gene variant with mandibular prognathism","volume":"94","author":"Perillo","year":"2015","journal-title":"J Dent Res"}],"container-title":["American Journal of Orthodontics and Dentofacial Orthopedics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889540617304468?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889540617304468?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T09:03:38Z","timestamp":1760173418000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889540617304468"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["S0889540617304468"],"URL":"https:\/\/doi.org\/10.1016\/j.ajodo.2017.01.021","relation":{},"ISSN":["0889-5406"],"issn-type":[{"value":"0889-5406","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genome-wide association study for mandibular prognathism using microsatellite and pooled DNA method","name":"articletitle","label":"Article Title"},{"value":"American Journal of Orthodontics and Dentofacial Orthopedics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajodo.2017.01.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 by the American Association of Orthodontists. All rights reserved.","name":"copyright","label":"Copyright"}]}}