{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:54:50Z","timestamp":1792101290170,"version":"4.4.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2004,12]]},"DOI":"10.1016\/j.ajog.2004.07.059","type":"journal-article","created":{"date-parts":[[2004,12,10]],"date-time":"2004-12-10T09:33:26Z","timestamp":1102671206000},"page":"1858-1862","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["National Institute on Drug Abuse Conference report on placental proteins, drug transport, and fetal development"],"prefix":"10.1016","volume":"191","author":[{"given":"Pushpa V.","family":"Thadani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"Jerome F.","family":"Strauss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudhansu K.","family":"Dey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia M.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth L.","family":"Audus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen S.","family":"Coats","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James C.","family":"Cross","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Erlebacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vadivel","family":"Ganapathy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel I.","family":"Linzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard K.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald A.","family":"Novak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rao S.","family":"Rapaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoel","family":"Sadovsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolyn M.","family":"Salafia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Soares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jashvant","family":"Unadkat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2004.07.059_bib1","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/S0002-9378(97)70022-X","article-title":"The association between maternal cocaine use and placenta previa","volume":"177","author":"Macones","year":"1997","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2004.07.059_bib2","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1080\/791200704","article-title":"Smoking, sex of the offspring, and risk of placental abruption, placenta previa, and preeclampsia: a population-based cohort study","volume":"80","author":"Mortensen","year":"2001","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.ajog.2004.07.059_bib3","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/S0889-8545(03)00068-8","article-title":"Substance use disorders in women: special considerations during pregnancy","volume":"30","author":"Bolnick","year":"2003","journal-title":"Obstet Gynecol Clin North Am"},{"key":"10.1016\/j.ajog.2004.07.059_bib4","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1055\/s-2003-42336","article-title":"Treatment of substance abuse during pregnancy and infant outcome","volume":"20","author":"Little","year":"2003","journal-title":"Am J Perinatol"},{"key":"10.1016\/j.ajog.2004.07.059_bib5","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1139\/y01-080","article-title":"The role of the placenta in variability of fetal exposure to cocaine and cannabinoids: a twin study","volume":"79","author":"Boskovic","year":"2001","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1016\/j.ajog.2004.07.059_bib6","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1097\/01.nrl.0000094941.96358.d1","article-title":"Fetal alcohol","volume":"9","author":"Chiriboga","year":"2003","journal-title":"Neurologist"},{"key":"10.1016\/j.ajog.2004.07.059_bib7","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1111\/j.1530-0277.2003.tb04401.x","article-title":"Executive functioning in preschool-age children prenatally exposed to alcohol, cocaine, and marijuana","volume":"27","author":"Noland","year":"2003","journal-title":"Alcohol Clin Exp Res"},{"key":"10.1016\/j.ajog.2004.07.059_bib8","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/00004703-200302000-00006","article-title":"Effects of prenatal methamphetamine exposure on fetal growth and drug withdrawal symptoms in infants born at term","volume":"24","author":"Smith","year":"2003","journal-title":"J Dev Behav Pediatr"},{"key":"10.1016\/j.ajog.2004.07.059_bib9","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s100249900102","article-title":"Effects of cocaine on the placenta","volume":"2","author":"Cejtin","year":"1999","journal-title":"Pediatr Dev Pathol"},{"key":"10.1016\/j.ajog.2004.07.059_bib10","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1053\/plac.2002.0926","article-title":"Identification of the CB1 cannabinoid receptor and fatty acid amide hydrolase (FAAH) in the human placenta","volume":"24","author":"Park","year":"2003","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2004.07.059_bib11","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1016\/S0024-3205(99)00503-2","article-title":"Transfer of morphine across the human placenta and its interaction with naloxone","volume":"65","author":"Kopecky","year":"1999","journal-title":"Life Sci"},{"key":"10.1016\/j.ajog.2004.07.059_bib12","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1353\/hpu.2010.0700","article-title":"Maternal drug use and the timing of prenatal care","volume":"14","author":"Brady","year":"2003","journal-title":"J Health Care Poor Underserved"},{"key":"10.1016\/j.ajog.2004.07.059_bib13","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/S0889-8545(03)00078-0","article-title":"Pharmacology of drugs of abuse","volume":"30","author":"Reynolds","year":"2003","journal-title":"Obstet Gynecol Clin North Am"},{"key":"10.1016\/j.ajog.2004.07.059_bib14","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/S0892-0362(00)00111-2","article-title":"Dose-related differences in the distribution of cocaine in the maternal-fetoplacental compartments in rats","volume":"22","author":"Morishima","year":"2000","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.ajog.2004.07.059_bib15","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/S0892-0362(99)00022-7","article-title":"Cocaine decreases uteroplacental blood flow in the rat","volume":"21","author":"Patel","year":"1999","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.ajog.2004.07.059_bib16","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0892-0362(01)00209-4","article-title":"Prenatal cocaine exposure induces an attenuation of uterine blood flow in the rat","volume":"24","author":"Lipton","year":"2002","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.ajog.2004.07.059_bib17","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1373\/49.2.230","article-title":"Real-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissues","volume":"49","author":"Langmann","year":"2003","journal-title":"Clin Chem"},{"key":"10.1016\/j.ajog.2004.07.059_bib18","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0169-409X(02)00169-2","article-title":"Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview","volume":"55","author":"Schnikel","year":"2002","journal-title":"Adv Drug Deliv Rev"},{"key":"10.1016\/j.ajog.2004.07.059_bib19","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S0890-6238(98)00027-6","article-title":"Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice","volume":"12","author":"Lankas","year":"1998","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.ajog.2004.07.059_bib20","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1097\/00002030-200305230-00011","article-title":"Pharmacokinetics of nelfinavir and indinavir in HIV-1-infected pregnant women","volume":"17","author":"Kosel","year":"2003","journal-title":"AIDS"},{"key":"10.1016\/j.ajog.2004.07.059_bib21","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1053\/plac.2002.0876","article-title":"The presence of inducible cytochrome P450 types 1A1 and 1A2 in the BeWo cell line","volume":"24","author":"Avery","year":"2003","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2004.07.059_bib22","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1124\/dmd.31.2.153","article-title":"The presence of xenobiotic transporters in rat placenta","volume":"31","author":"Leazer","year":"2003","journal-title":"Drug Metabol Dispos"},{"key":"10.1016\/j.ajog.2004.07.059_bib23","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0022-3565(24)39087-1","article-title":"Placental transporters relevant to drug distribution across the maternal-fetal interface","volume":"294","author":"Ganapathy","year":"2000","journal-title":"J Pharmacol Exper Therap"},{"key":"10.1016\/j.ajog.2004.07.059_bib24","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1016\/0024-3205(95)00149-Z","article-title":"Effect of chronic cocaine administration on amino acid uptake in rat placental vesicles","volume":"56","author":"Novak","year":"1995","journal-title":"Life Sci"},{"key":"10.1016\/j.ajog.2004.07.059_bib25","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1071\/RD9910355","article-title":"Placental toxicology: tobacco smoke, abused drugs, multiple chemical interactions, and placental function","volume":"3","author":"Sastry","year":"1991","journal-title":"Reprod Fertil Dev"},{"key":"10.1016\/j.ajog.2004.07.059_bib26","doi-asserted-by":"crossref","first-page":"C153","DOI":"10.1152\/ajpcell.2002.282.1.C153","article-title":"Physiological importance of system A-mediated amino acid transport to rat fetal development","volume":"282","author":"Cramer","year":"2002","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.ajog.2004.07.059_bib27","series-title":"Nutrition in pediatrics","first-page":"442","article-title":"Fetal nutrition and imprinting","author":"Bernstein","year":"2003"},{"key":"10.1016\/j.ajog.2004.07.059_bib28","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0009-3084(02)00156-1","article-title":"Endocannabinoid signaling in synchronizing embryo development and uterine receptivity for implantation","volume":"121","author":"Paria","year":"2002","journal-title":"Chem Phys Lipids"},{"key":"10.1016\/j.ajog.2004.07.059_bib29","doi-asserted-by":"crossref","first-page":"14914","DOI":"10.1073\/pnas.2436379100","article-title":"Differential G-protein coupled cannabinoid receptor signaling by anandamide directs blastocyst activation for implantation","volume":"100","author":"Wang","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ajog.2004.07.059_bib30","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1128\/MCB.20.2.530-541.2000","article-title":"The HAND1 basic Helix-Loop-Helix transcription factor regulates trophoblast differentiation via multiple mechanisms","volume":"20","author":"Scott","year":"2000","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.ajog.2004.07.059_bib31","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1006\/dbio.2002.0773","article-title":"Interactions between trophoblast cells and the maternal and fetal circulation in the mouse placenta","volume":"250","author":"Adamson","year":"2002","journal-title":"Dev Biol"},{"key":"10.1016\/j.ajog.2004.07.059_bib32","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1053\/plac.2002.0887","article-title":"Genes, development and evolution of the placenta","volume":"24","author":"Cross","year":"2003","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2004.07.059_bib33","first-page":"109","article-title":"A variable fold-change threshold determines significance for expression microarrays","volume":"10","author":"Mariani","year":"2002","journal-title":"FASEB J"},{"key":"10.1016\/j.ajog.2004.07.059_bib34","doi-asserted-by":"crossref","first-page":"4281","DOI":"10.1210\/en.2002-220447","article-title":"Two placental hormones are agonists in stimulating megakaryocyte growth and differentiation","volume":"143","author":"Zhou","year":"2002","journal-title":"Endocrinology"},{"key":"10.1016\/j.ajog.2004.07.059_bib35","series-title":"Prolactin","first-page":"139","article-title":"Rodent prolactin family and pregnancy","author":"Soares","year":"2001"},{"key":"10.1016\/j.ajog.2004.07.059_bib36","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/S0012-1606(03)00210-0","article-title":"Gestation stage-dependent intrauterine trophoblast cell invasion in the rat and mouse: novel endocrine phenotype and regulation","volume":"260","author":"Ain","year":"2003","journal-title":"Dev Biol"},{"key":"10.1016\/j.ajog.2004.07.059_bib37","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/S0952-7915(00)00264-8","article-title":"Why isn't the fetus rejected?","volume":"13","author":"Erlebacher","year":"2001","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.ajog.2004.07.059_bib38","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1089\/thy.1999.9.643","article-title":"The immunology of pregnancy","volume":"9","author":"Weetman","year":"1999","journal-title":"Thyroid"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937804008439?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937804008439?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T09:45:45Z","timestamp":1757583945000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937804008439"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,12]]},"references-count":38,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2004,12]]}},"alternative-id":["S0002937804008439"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2004.07.059","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2004,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"National Institute on Drug Abuse Conference report on placental proteins, drug transport, and fetal development","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2004.07.059","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}