{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T19:21:15Z","timestamp":1762111275949,"version":"3.44.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2006,3]]},"DOI":"10.1016\/j.ajog.2006.01.003","type":"journal-article","created":{"date-parts":[[2006,3,8]],"date-time":"2006-03-08T07:21:26Z","timestamp":1141802486000},"page":"681-686","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Prevention of alcohol-induced learning deficits in fetal alcohol syndrome mediated through NMDA and GABA receptors"],"prefix":"10.1016","volume":"194","author":[{"given":"Laura","family":"Toso","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah H.","family":"Poggi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin","family":"Roberson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jade","family":"Woodard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Abebe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine Y.","family":"Spong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2006.01.003_bib1","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1542\/peds.106.2.358","article-title":"Committee on Substance Abuse and Committee on Children with Disabilities. Fetal alcohol syndrome and alcohol-related neurodevelopmental disorders","volume":"106","author":"American Academy of Pediatrics","year":"2000","journal-title":"Pediatrics"},{"key":"10.1016\/j.ajog.2006.01.003_bib2","doi-asserted-by":"crossref","first-page":"2996","DOI":"10.1001\/jama.290.22.2996","article-title":"Fetal alcohol spectrum disorder","volume":"290","author":"Sokol","year":"2003","journal-title":"JAMA"},{"key":"10.1016\/j.ajog.2006.01.003_bib3","unstructured":"US Surgeon General Warning. Advisory on alcohol use during pregnancy. February 2005. Available at: http:\/\/www.hhs.gov\/surgeongeneral\/pressreleases\/sg02222005.html. Accessed January 17, 2006."},{"key":"10.1016\/j.ajog.2006.01.003_bib4","unstructured":"Centers for Disease Control and Prevention (CDC). Behavioral risk factor surveillance system. Atlanta, GA: US Department of Health and Human Services, CDC. Available at: http:\/\/www.cdc.gov\/brfss. Accessed January 17, 2006."},{"key":"10.1016\/j.ajog.2006.01.003_bib5","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1016\/j.ajog.2005.02.105","article-title":"N-methyl-D-aspartate subunit expression during mouse development altered by in utero alcohol exposure","volume":"193","author":"Toso","year":"2005","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2006.01.003_bib6","first-page":"305","article-title":"GABAergic cells and signals in CNS development","volume":"5","author":"Barker","year":"1998","journal-title":"Perspect Dev Neurobiol"},{"key":"10.1016\/j.ajog.2006.01.003_bib7","first-page":"727","article-title":"Prenatal alcohol exposure alters GABAA\u03b15 expression: a mechanism of alcohol-induced learning dysfunction","volume":"192","author":"Toso","year":"2005","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2006.01.003_bib8","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/S0022-3565(24)29596-3","article-title":"Prevention of fetal demise and growth restriction in a mouse model of fetal alcohol syndrome","volume":"297","author":"Spong","year":"2001","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.ajog.2006.01.003_bib9","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.ajog.2005.02.101","article-title":"Novel peptides prevent alcohol-induced spatial learning deficits and proinflammatory cytokine release in a mouse model of fetal alcohol syndrome","volume":"193","author":"Vink","year":"2005","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2006.01.003_bib10","first-page":"227","article-title":"Teratogenesis after acute alcohol exposure in inbred and outbred mice","volume":"2","author":"Webster","year":"1980","journal-title":"Neurobehav Toxicol"},{"key":"10.1016\/j.ajog.2006.01.003_bib11","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1210\/endo.140.2.6481","article-title":"Maternal regulation of embryonic growth: the role of vasoactive intestinal peptide","volume":"140","author":"Spong","year":"1999","journal-title":"Endocrinology"},{"key":"10.1016\/j.ajog.2006.01.003_bib12","first-page":"481","article-title":"Injections of the neuroprotective peptide NAP to newborn mice attenuate head-injury-related dysfunction in adults","volume":"14","author":"Zaltman","year":"2003","journal-title":"Neropharm Toxicol"},{"key":"10.1016\/j.ajog.2006.01.003_bib13","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1749-6632.2000.tb06956.x","article-title":"Chemiokines released from astroglia by vasoactive intestinal peptide. Mechanism of neuroprotection from HIV envelope protein toxicity","volume":"921","author":"Brenneman","year":"2000","journal-title":"Ann NY Acad Sci"},{"key":"10.1016\/j.ajog.2006.01.003_bib14","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1016\/j.peptides.2003.08.005","article-title":"The neuroprotective peptide NAP inhibits the aggregation of the beta-amyloid peptide","volume":"24","author":"Ashur-Fabian","year":"2003","journal-title":"Peptides"},{"key":"10.1016\/j.ajog.2006.01.003_bib15","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0006-8993(99)02375-6","article-title":"Vasoactive intestinal peptide (VIP) prevents neurotoxicity in neuronal cultures: relevance to neuroprotection in Parkinson's disease","volume":"854","author":"Offen","year":"2000","journal-title":"Brain Res"},{"key":"10.1016\/j.ajog.2006.01.003_bib16","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1749-6632.1999.tb07883.x","article-title":"VIP neuroprotection against excitotoxic lesions of the developing mouse brain","volume":"897","author":"Gressens","year":"1999","journal-title":"Ann NY Acad Sci"},{"key":"10.1016\/j.ajog.2006.01.003_bib17","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1385\/JMN:24:2:189","article-title":"A neuroprotective peptide antagonizes fetal alcohol exposure-compromised brain growth","volume":"24","author":"Chen","year":"2004","journal-title":"J Mol Neurosci"},{"key":"10.1016\/j.ajog.2006.01.003_bib18","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.ajog.2005.05.052","article-title":"Prevention of alcohol-induced developmental delays and learning abnormalities in a model of fetal alcohol syndrome","volume":"193","author":"Endres","year":"2005","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2006.01.003_bib19","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1067\/S0002-9378(03)00834-2","article-title":"The role of activity-dependent neuroprotective protein in a mouse model of fetal alcohol syndrome","volume":"189","author":"Poggi","year":"2003","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2006.01.003_bib20","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0167-0115(02)00104-0","article-title":"Vasoactive intestinal peptide mRNA and immunoreactivity are decreased in fetal alcohol syndrome model","volume":"108","author":"Spong","year":"2003","journal-title":"Regul Pept"},{"key":"10.1016\/j.ajog.2006.01.003_bib21","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/S0022-3565(24)37441-5","article-title":"Activity-dependent neurotrophic factor: structure-activity relationships of femtomolar-acting peptides","volume":"285","author":"Brenneman","year":"1998","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.ajog.2006.01.003_bib22","doi-asserted-by":"crossref","first-page":"S37","DOI":"10.3233\/JAD-2004-6S605","article-title":"The femtomolar-acting NAP interacts with microtubules: novel aspects of astrocyte protection","volume":"6","author":"Gozes","year":"2004","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.ajog.2006.01.003_bib23","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0006-8993(00)02259-9","article-title":"CREB contributes to increased neurite outgrowth of sensory neurons induced by vasoactive intestinal polypeptide and activity-dependent neurotrophic factor","volume":"868","author":"White","year":"2000","journal-title":"Brain Research"},{"key":"10.1016\/j.ajog.2006.01.003_bib24","doi-asserted-by":"crossref","first-page":"3529","DOI":"10.1523\/JNEUROSCI.20-10-03529.2000","article-title":"Developmentally regulated NMDA receptor-dependent dephosphorylation of cAMP response element-binding protein (CREB) in hippocampal neurons","volume":"12","author":"Sala","year":"2000","journal-title":"J Neurosci"},{"key":"10.1016\/j.ajog.2006.01.003_bib25","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1002\/(SICI)1098-1063(1996)6:4<347::AID-HIPO1>3.0.CO;2-I","article-title":"Interneurons of the hippocampus","volume":"6","author":"Freund","year":"1996","journal-title":"Hippocampus"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937806000469?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937806000469?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T10:17:30Z","timestamp":1757585850000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937806000469"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,3]]}},"alternative-id":["S0002937806000469"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2006.01.003","relation":{},"ISSN":["0002-9378"],"issn-type":[{"type":"print","value":"0002-9378"}],"subject":[],"published":{"date-parts":[[2006,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prevention of alcohol-induced learning deficits in fetal alcohol syndrome mediated through NMDA and GABA receptors","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2006.01.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}