{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T17:53:39Z","timestamp":1768586019304,"version":"3.49.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2007,4,1]],"date-time":"2007-04-01T00:00:00Z","timestamp":1175385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,4,1]],"date-time":"2007-04-01T00:00:00Z","timestamp":1175385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2007,4]]},"DOI":"10.1016\/j.ajog.2006.10.897","type":"journal-article","created":{"date-parts":[[2007,4,2]],"date-time":"2007-04-02T07:12:44Z","timestamp":1175497964000},"page":"363.e1-363.e7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":92,"title":["Usefulness of a placental profile in high-risk pregnancies"],"prefix":"10.1016","volume":"196","author":[{"given":"Meghana","family":"Toal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shafagh","family":"Fallah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fawaz","family":"Alkazaleh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vandana","family":"Chaddha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rory C.","family":"Windrim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John C.P.","family":"Kingdom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2006.10.897_bib1","series-title":"Williams obstetrics","first-page":"761","article-title":"Hypertensive disorders in pregnancy","year":"2005"},{"key":"10.1016\/j.ajog.2006.10.897_bib2","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1111\/j.1471-0528.2006.00852.x","article-title":"The Scottish Perinatal Neuropathology study: clinicopathological correlation with stillbirths","volume":"113","author":"Becher","year":"2006","journal-title":"BJOG"},{"key":"10.1016\/j.ajog.2006.10.897_bib3","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1067\/S0002-9378(03)00576-3","article-title":"The frequency and severity of placental findings in women with preeclampsia are gestational age dependent","volume":"189","author":"Moldenhauer","year":"2003","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2006.10.897_bib4","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.placenta.2004.03.002","article-title":"Prognostic value of placental ultrasound in pregnancies complicated by absent end-diastolic flow velocity in the umbilical arteries","volume":"25","author":"Viero","year":"2004","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2006.10.897_bib5","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.siny.2004.03.006","article-title":"Developmental biology of the placenta and the origins of placental insufficiency","volume":"9","author":"Chaddha","year":"2004","journal-title":"Semin Fetal Neonatal Med"},{"key":"10.1016\/j.ajog.2006.10.897_bib6","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1053\/plac.1999.0395","article-title":"Uterine Doppler velocimetry and placental hypoxic-ischemic lesion in pregnancies with fetal intrauterine growth restriction","volume":"20","author":"Ferrazzi","year":"1999","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2006.10.897_bib7","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1399-0004.2005.00546.x","article-title":"Ultrasound detection of placental insufficiency in women with \u201cunexplained\u201d abnormal maternal serum screening results","volume":"69","author":"Whittle","year":"2006","journal-title":"Clin Genet"},{"key":"10.1016\/j.ajog.2006.10.897_bib8","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1056\/NEJM199107043250102","article-title":"Second-trimester maternal serum alpha-fetoprotein levels and the risk of subsequent fetal death","volume":"325","author":"Waller","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajog.2006.10.897_bib9","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1067\/mob.2003.278","article-title":"Association between second-trimester isolated high maternal serum human chorionic gonadotropin levels and obstetric complications in singleton and twin pregnancies","volume":"188","author":"LePage","year":"2003","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2006.10.897_bib10","first-page":"78","article-title":"Improved prediction of preeclampsia by two-stage screening of uterine arteries using the early diastolic notch and color Doppler imaging","volume":"82","author":"Bower","year":"1993","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2006.10.897_bib11","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/S0002-9378(94)70397-3","article-title":"Ultrasonographic investigation of placental morphological characteristics and size during the second trimester of pregnancy","volume":"170","author":"Jauniaux","year":"1994","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2006.10.897_bib12","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1002\/uog.2641","article-title":"Comparison between three-dimensional placental volume at 12 weeks and uterine artery impedance\/notching at 22 weeks in screening for pregnancy-induced hypertension, pre-eclampsia and fetal growth restriction in a low-risk population","volume":"27","author":"Hafner","year":"2006","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajog.2006.10.897_bib13","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1159\/000081369","article-title":"Prediction of preeclampsia or intrauterine growth restriction by second trimester serum screening and uterine Doppler velocimetry","volume":"20","author":"Audibert","year":"2005","journal-title":"Fetal Diagn Ther"},{"key":"10.1016\/j.ajog.2006.10.897_bib14","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1046\/j.1469-0705.1998.12050339.x","article-title":"The role of color Doppler imaging of the uterine arteries at 20 weeks\u2019 gestation in stratifying antenatal care","volume":"12","author":"Kurdi","year":"1998","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajog.2006.10.897_bib15","first-page":"619","article-title":"First trimester Maternal Serum Biochemistry and Fetal Nuchal Translucency Screening (BUN) study group: first trimester screening for trisomies 21 and 18","volume":"350","author":"Wapner","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajog.2006.10.897_bib16","article-title":"Antiplatelet agents for preventing pre-eclampsia and its complications","volume":"1","author":"Duley","year":"2004","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ajog.2006.10.897_bib17","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/S0140-6736(99)80010-5","article-title":"Effect of antioxidants on the occurrence of pre-eclampsia in women at increased risk: a randomised trial","volume":"354","author":"Chappell","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.ajog.2006.10.897_bib18","series-title":"Intrauterine growth restriction","first-page":"257","article-title":"Diagnosis and management of intrauterine growth restriction","author":"Smith","year":"1999"},{"key":"10.1016\/j.ajog.2006.10.897_bib19","first-page":"159","article-title":"Diagnosis and management of preeclampsia and eclampsia: ACOG practice bulletin no. 33","volume":"99","year":"2002","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2006.10.897_bib20","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/S0143-4004(05)80383-2","article-title":"The relationship of uterine and umbilical Doppler resistance to fetal and placental protein synthesis in the second trimester","volume":"14","author":"Bewley","year":"1993","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2006.10.897_bib21","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1016\/S0002-9378(12)80033-0","article-title":"Elevated maternal serum alpha-fetoprotein levels and midtrimester placental abnormalities in relation to subsequent adverse pregnancy outcomes","volume":"167","author":"Williams","year":"1992","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2006.10.897_bib22","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.ajog.2004.12.014","article-title":"Fetal Medicine Foundation Second Trimester Screening group: an integrated model for the prediction of preeclampsia using maternal factors and uterine artery Doppler velocimetry in unselected low-risk women","volume":"193","author":"Yu","year":"2005","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2006.10.897_bib23","first-page":"180","article-title":"Psychological implications of high-risk pregnancy","volume":"50","author":"Cumberbatch","year":"2005","journal-title":"Int J Fertil Womens Med"},{"key":"10.1016\/j.ajog.2006.10.897_bib24","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1159\/000091814","article-title":"Evaluation of factor V Leiden, prothrombin and methylenetetrahydrofolate reductase gene mutations in patients with severe pregnancy complications in Northern Finland","volume":"62","author":"Jarvenpaa","year":"2006","journal-title":"Gynecol Obstet Invest"},{"key":"10.1016\/j.ajog.2006.10.897_bib25","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/uog.218","article-title":"Randomized controlled trial using low-dose aspirin in the prevention of pre-eclampsia in women with abnormal uterine artery Doppler at 23 weeks\u2019 gestation","volume":"22","author":"Yu","year":"2003","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajog.2006.10.897_bib26","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1097\/01.moh.0000239711.55544.9b","article-title":"Prophylaxis and treatment of thrombophilia in pregnancy","volume":"13","author":"Gris","year":"2006","journal-title":"Curr Opin Hematol"},{"key":"10.1016\/j.ajog.2006.10.897_bib27","doi-asserted-by":"crossref","first-page":"3695","DOI":"10.1182\/blood-2003-12-4250","article-title":"Low-molecular-weight heparin versus low-dose aspirin in women with one fetal loss and a constitutional thrombophilic disorder","volume":"103","author":"Gris","year":"2004","journal-title":"Blood"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937806022125?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937806022125?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T10:20:18Z","timestamp":1757586018000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937806022125"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,4]]}},"alternative-id":["S0002937806022125"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2006.10.897","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2007,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Usefulness of a placental profile in high-risk pregnancies","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2006.10.897","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}