{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T21:57:57Z","timestamp":1780523877364,"version":"3.54.1"},"reference-count":15,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2007,8,1]],"date-time":"2007-08-01T00:00:00Z","timestamp":1185926400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,8,1]],"date-time":"2007-08-01T00:00:00Z","timestamp":1185926400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2007,8,1]],"date-time":"2007-08-01T00:00:00Z","timestamp":1185926400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2007,8,1]],"date-time":"2007-08-01T00:00:00Z","timestamp":1185926400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2007,8,1]],"date-time":"2007-08-01T00:00:00Z","timestamp":1185926400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2007,8,1]],"date-time":"2007-08-01T00:00:00Z","timestamp":1185926400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2007,8,1]],"date-time":"2007-08-01T00:00:00Z","timestamp":1185926400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2007,8]]},"DOI":"10.1016\/j.ajog.2007.03.057","type":"journal-article","created":{"date-parts":[[2007,8,7]],"date-time":"2007-08-07T08:33:30Z","timestamp":1186475610000},"page":"181.e1-181.e5","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Screening for structural fetal anomalies during the nuchal translucency ultrasound examination"],"prefix":"10.1016","volume":"197","author":[{"given":"Zeev","family":"Weiner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Israel","family":"Goldstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan","family":"Bombard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liat","family":"Applewhite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Itzkovits-Eldor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2007.03.057_bib1","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1056\/NEJMoa043693","article-title":"First-trimester or second-trimester screening, or both, for Down\u2019s syndrome","volume":"353","author":"Malone","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajog.2007.03.057_bib2","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/S0140-6736(97)11280-6","article-title":"UK multicenter project on assessment of risk of trisomy 21 by maternal age and fetal nuchal-translucency thickness at 10-14 weeks of gestation","volume":"352","author":"Snijders","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.ajog.2007.03.057_bib3","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1002\/uog.1936","article-title":"Relationship between nuchal translucency thickness and prevalence of major cardiac defects in fetuses with normal karyotype","volume":"26","author":"Atzei","year":"2005","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.03.057_bib4","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1016\/j.ajog.2004.05.049","article-title":"Fetal cardiac defects and increased nuchal translucency thickness: a prospective study","volume":"19","author":"McAuliffe","year":"2004","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.03.057_bib5","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.ajog.2004.06.081","article-title":"Nuchal translucency and fetal cardiac defects: a pooled analysis of major echocardiography centers","volume":"192","author":"Makrydimas","year":"2005","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.03.057_bib6","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1067\/S0002-9378(03)00645-8","article-title":"Screening performance of first-trimester nuchal translucency for major cardiac defects: a meta-analysis","volume":"189","author":"Makrydimas","year":"2003","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.03.057_bib7","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1002\/jcu.1870190905","article-title":"Choroid plexus dysmorphism detected by transvaginal sonography: the earliest sign of fetal hydrocephalus","volume":"19","author":"Bronshtein","year":"1991","journal-title":"J Clin Ultrasound"},{"key":"10.1016\/j.ajog.2007.03.057_bib8","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1002\/(SICI)1097-0223(199708)17:8<753::AID-PD148>3.0.CO;2-P","article-title":"Screening for fetal anomalies in the 12th week of pregnancy by transvaginal sonography in an unselected population","volume":"17","author":"Hernadi","year":"1997","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.ajog.2007.03.057_bib9","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1111\/j.1471-0528.1998.tb09350.x","article-title":"First trimester ultrasonographic diagnosis of fetal structural abnormalities in a low risk population","volume":"105","author":"Economides","year":"1998","journal-title":"Br J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.03.057_bib10","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1002\/uog.1775","article-title":"Assessment of fetal anatomy at 11-14 weeks ultrasound examination","volume":"24","author":"Souka","year":"2004","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.03.057_bib11","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.ajog.2005.08.032","article-title":"Screening for major structural abnormalities at the 11- to 14-week ultrasound scan","volume":"194","author":"Souka","year":"2006","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.03.057_bib12","doi-asserted-by":"crossref","first-page":"23","DOI":"10.7863\/jum.2002.21.1.23","article-title":"Diagnosis of congenital cardiac defects between 11 and 14 weeks\u2019 gestation in high-risk patients","volume":"21","author":"Weiner","year":"2002","journal-title":"J Ultrasound Med"},{"key":"10.1016\/j.ajog.2007.03.057_bib13","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/uog.2822","article-title":"Increased nuchal translucency in arthrogryposis, renal dysfunction and cholestasis syndrome and discovery of a Portuguese specific mutation in the VPS33B gene","volume":"28","author":"Sanseverino","year":"2006","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.03.057_bib14","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1002\/pd.1294","article-title":"Apert syndrome associated with increased fetal nuchal translucency","volume":"25","author":"Allem","year":"2005","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.ajog.2007.03.057_bib15","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1002\/pd.121","article-title":"Congenital nephritic syndrome presenting with increased nuchal translucency in the first trimester","volume":"22","author":"Suoka","year":"2002","journal-title":"Prenat Diagn"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937807004231?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937807004231?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T10:23:32Z","timestamp":1757586212000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937807004231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,8]]}},"alternative-id":["S0002937807004231"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2007.03.057","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2007,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Screening for structural fetal anomalies during the nuchal translucency ultrasound examination","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2007.03.057","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}