{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:33:17Z","timestamp":1791307997242,"version":"4.3.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2008,3]]},"DOI":"10.1016\/j.ajog.2007.09.031","type":"journal-article","created":{"date-parts":[[2008,3,3]],"date-time":"2008-03-03T14:08:23Z","timestamp":1204553303000},"page":"330.e1-330.e7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":87,"title":["Determinants of adverse perinatal outcome in high-risk women with abnormal uterine artery Doppler images"],"prefix":"10.1016","volume":"198","author":[{"given":"Meghana","family":"Toal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Keating","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoff","family":"Machin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jodie","family":"Dodd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Lee","family":"Adamson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rory C.","family":"Windrim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John C.P.","family":"Kingdom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2007.09.031_bib1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.3109\/00016346509153973","article-title":"An arteriographic study of the blood flow through the uterus and the placenta at mid-pregnancy","volume":"44","author":"Borell","year":"1965","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.ajog.2007.09.031_bib2","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1046\/j.1471-0528.2003.t01-1-02163.x","article-title":"Longitudinal quantification of uterine artery blood volume flow changes during gestation in pregnancies complicated by intrauterine growth restriction","volume":"110","author":"Konje","year":"2003","journal-title":"BJOG"},{"key":"10.1016\/j.ajog.2007.09.031_bib3","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/S0143-4004(98)91048-7","article-title":"The investigation of placental relaxation and estimation of placental perfusion using echo-planar magnetic resonance imaging","volume":"19","author":"Duncan","year":"1998","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2007.09.031_bib4","first-page":"78","article-title":"Improved prediction of preeclampsia by two-stage screening of uterine arteries using the early diastolic notch and color Doppler imaging","volume":"82","author":"Bower","year":"1993","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.09.031_bib5","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1046\/j.0960-7692.2001.00572.x","article-title":"Multicenter screening for pre-eclampsia and fetal growth restriction by transvaginal uterine artery Doppler at 23 weeks of gestation","volume":"18","author":"Papageorghiou","year":"2001","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.09.031_bib6","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/j.1471-0528.1983.tb06739.x","article-title":"Uteroplacental blood flow index in intrauterine growth retardation of fetal or maternal origin","volume":"90","author":"Nylund","year":"1983","journal-title":"BJOG"},{"key":"10.1016\/j.ajog.2007.09.031_bib7","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1067\/mob.2002.126866","article-title":"Punch biopsy of the human placental bed","volume":"187","author":"Robson","year":"2002","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.09.031_bib8","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0028-2243(93)90265-E","article-title":"A high uterine artery pulsatility index reflects a defective development of placental bed spiral arteries in pregnancies complicated by hypertension and fetal growth retardation","volume":"49","author":"Olofsson","year":"1993","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ajog.2007.09.031_bib9","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1038\/labinvest.3780326","article-title":"Macrophage-induced apoptosis limits endovascular trophoblast invasion in the uterine wall of preeclamptic women","volume":"81","author":"Reister","year":"2001","journal-title":"Lab Invest"},{"key":"10.1016\/j.ajog.2007.09.031_bib10","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.placenta.2004.03.002","article-title":"Prognostic value of placental ultrasound in pregnancies complicated by absent end-diastolic flow velocity in the umbilical arteries","volume":"25","author":"Viero","year":"2004","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2007.09.031_bib11","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1067\/S0002-9378(03)00576-3","article-title":"The frequency and severity of placental findings in women with preeclampsia are gestational age dependent","volume":"189","author":"Moldenhauer","year":"2003","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.09.031_bib12","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1046\/j.1469-0705.1998.12050339.x","article-title":"The role of color Doppler imaging of the uterine arteries at 20 weeks\u2019 gestation in stratifying antenatal care","volume":"12;","author":"Kurdi","year":"1998","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.09.031_bib13","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/j.1471-0528.2000.tb11690.x","article-title":"How useful is uterine artery Doppler flow velocimetry in the prediction of pre-eclampsia, intrauterine growth retardation and perinatal death?","volume":"107","author":"Chien","year":"2000","journal-title":"BJOG"},{"key":"10.1016\/j.ajog.2007.09.031_bib14","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1046\/j.1469-0705.2000.00014.x","article-title":"Mid-trimester uterine artery Doppler screening as a predictor of adverse pregnancy outcome in high-risk women","volume":"15","author":"Coleman","year":"2000","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.09.031_bib15","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.ajog.2005.09.010","article-title":"Second-trimester prediction of severe placental complications in women with combined elevations in alpha-fetoprotein and human chorionic gonadotrophin","volume":"194","author":"Alkazaleh","year":"2006","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.09.031_bib16","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/0002-9378(92)91700-K","article-title":"Venous drainage of the human uterus: respiratory gas studies in normal and fetal growth-retarded pregnancies","volume":"166","author":"Pardi","year":"1992","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.09.031_bib17","doi-asserted-by":"crossref","first-page":"363.e1","DOI":"10.1016\/j.ajog.2006.10.897","article-title":"Usefulness of a placental profile in high risk pregnancies","volume":"196","author":"Toal","year":"2007","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.09.031_bib18","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/S0002-9378(94)70397-3","article-title":"Ultrasonographic investigation of placental morphological characteristics and size during the second trimester of pregnancy","volume":"170","author":"Jauniaux","year":"1994","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.09.031_bib19","first-page":"159","article-title":"Diagnosis and management of preeclampsia and eclampsia","volume":"99","year":"2002","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.09.031_bib20","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0002-9440(10)65123-1","article-title":"Preeclampsia is associated with widespread apoptosis of placental cytotrophoblasts within the uterine wall","volume":"155","author":"DiFederico","year":"1999","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ajog.2007.09.031_bib21","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1111\/j.1471-0528.1998.tb09946.x","article-title":"Significance of a diastolic notch in the uterine artery flow velocity waveform induced by uterine embolisation in the pregnant ewe","volume":"105","author":"Ochi","year":"1998","journal-title":"BJOG"},{"key":"10.1016\/j.ajog.2007.09.031_bib22","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1159\/000299924","article-title":"Comparison of uteroplacental blood flow in normal and in intrauterine growth-retarded pregnancy: measurements with Indium-113m and a computer-linked gamma camera","volume":"10","author":"Lunell","year":"1979","journal-title":"Gynecol Obstet Invest"},{"key":"10.1016\/j.ajog.2007.09.031_bib23","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/S0143-4004(97)90000-X","article-title":"Oxygen and placental villous development: origins of fetal hypoxia","volume":"18","author":"Kingdom","year":"1997","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2007.09.031_bib24","first-page":"499","article-title":"Umbilical Doppler waveforms and placental villous angiogenesis in pregnancies complicated by fetal growth restriction","volume":"93","author":"Todros","year":"1999","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.09.031_bib25","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1053\/plac.1999.0395","article-title":"Uterine Doppler velocimetry and placental hypoxic-ischemic lesion in pregnancies with fetal intrauterine growth restriction","volume":"20;","author":"Ferrazzi","year":"1999","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2007.09.031_bib26","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1053\/plac.2002.0945","article-title":"Histomorphology of the placenta and the placental bed of growth restricted foetuses and correlation with the Doppler velocimetries of the uterine and umbilical arteries","volume":"24","author":"Madazli","year":"2003","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2007.09.031_bib27","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1053\/plac.2001.0676","article-title":"Uterine artery Doppler flow and uteroplacental vascular pathology in normal pregnancies and pregnancies complicated by pre-eclampsia and small for gestational age fetuses","volume":"22","author":"Aardema","year":"2001","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2007.09.031_bib28","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1067\/mob.2002.127720","article-title":"Failure of physiologic transformation of the spiral arteries in the placental bed in preterm premature rupture of membranes","volume":"187","author":"Kim","year":"2002","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2007.09.031_bib29","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/0028-2243(91)90115-2","article-title":"Placental morphology in relation to umbilical artery blood velocity waveforms","volume":"40","author":"Nordenvall","year":"1991","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ajog.2007.09.031_bib30","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0002-9440(10)63803-5","article-title":"Trophoblastic oxidative stress in relation to temporal and regional differences in maternal placental blood flow in normal and abnormal early pregnancies","volume":"162","author":"Jauniaux","year":"2003","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ajog.2007.09.031_bib31","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/uog.218","article-title":"Randomized controlled trial using low-dose aspirin in the prevention of pre-eclampsia in women with abnormal uterine artery Doppler at 23 weeks\u2019 gestation","volume":"22","author":"Yu","year":"2003","journal-title":"Ultrasound Obstet Gynecol"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937807011295?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937807011295?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T10:31:08Z","timestamp":1757586668000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937807011295"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,3]]}},"alternative-id":["S0002937807011295"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2007.09.031","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2008,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Determinants of adverse perinatal outcome in high-risk women with abnormal uterine artery Doppler images","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2007.09.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}