{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T16:43:37Z","timestamp":1758041017598,"version":"3.44.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2009,9]]},"DOI":"10.1016\/j.ajog.2009.06.002","type":"journal-article","created":{"date-parts":[[2009,7,25]],"date-time":"2009-07-25T04:19:42Z","timestamp":1248495582000},"page":"322.e1-322.e6","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["The role of transforming growth factor \u03b2 in cervical remodeling within the rat cervix"],"prefix":"10.1016","volume":"201","author":[{"given":"Tanya","family":"Dailey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huiling","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vit","family":"Long","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward K.","family":"Chien","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2009.06.002_bib1","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1056\/NEJM199807303390506","article-title":"Prevention of premature birth","volume":"339","author":"Goldenberg","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajog.2009.06.002_bib3","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1067\/mob.2000.106766","article-title":"The Preterm Prediction Study: prediction of preterm premature rupture of membranes through clinical findings and ancillary testing. The National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network","volume":"183","author":"Mercer","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2009.06.002_bib4","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1056\/NEJM199602293340904","article-title":"The length of the cervix and the risk of spontaneous premature delivery","volume":"334","author":"Iams","year":"1996","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajog.2009.06.002_bib5","doi-asserted-by":"crossref","first-page":"3056","DOI":"10.3748\/wjg.v13.i22.3056","article-title":"Transforming growth factor-beta and fibrosis","volume":"13","author":"Verrecchia","year":"2007","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.ajog.2009.06.002_bib6","doi-asserted-by":"crossref","first-page":"283","DOI":"10.2741\/1184","article-title":"Wound healing: an overview of acute, fibrotic and delayed healing","volume":"9","author":"Diegelmann","year":"2004","journal-title":"Front Biosci"},{"key":"10.1016\/j.ajog.2009.06.002_bib7","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.jdermsci.2003.12.006","article-title":"TGF-\u03b2 induced SMAD signaling and gene regulation: consequences for extracellular matrix remodeling and wound healing","volume":"35","author":"Schiller","year":"2004","journal-title":"J Dermatol Sci"},{"key":"10.1016\/j.ajog.2009.06.002_bib8","first-page":"69","article-title":"Transforming growth factor-\u03b2: a key mediator of fibrosis","volume":"117","author":"Mauviel","year":"2005","journal-title":"Methods Mol Med"},{"key":"10.1016\/j.ajog.2009.06.002_bib9","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1478-3231.2005.01192.x","article-title":"Therapeutic strategies against TGF-\u03b2 signaling pathway in hepatic fibrosis","volume":"26","author":"Liu","year":"2006","journal-title":"Liver Int"},{"key":"10.1016\/j.ajog.2009.06.002_bib10","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1006\/mgme.2000.3032","article-title":"Induction of cardiac fibrosis by transforming growth factor-\u03b21","volume":"71","author":"Lijnen","year":"2000","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.ajog.2009.06.002_bib11","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1096\/fasebj.13.15.2105","article-title":"Specificity, diversity, and regulation in TGF-beta superfamily signaling","volume":"13","author":"Piek","year":"1999","journal-title":"FASEB J"},{"key":"10.1016\/j.ajog.2009.06.002_bib12","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/0955-2235(92)90017-C","article-title":"In vivo interactions of TGF-\u03b2 and extracellular matrix","volume":"4","author":"Noble","year":"1992","journal-title":"Prog Growth Factor Res"},{"key":"10.1016\/j.ajog.2009.06.002_bib13","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.autrev.2006.06.001","article-title":"Transforming growth factor-\u03b2 signaling through the Smad proteins: role in systemic sclerosis","volume":"5","author":"Verrecchia","year":"2006","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.ajog.2009.06.002_bib14","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/jcp.20948","article-title":"Regulation of matrix metalloproteinase gene expression","volume":"211","author":"Yan","year":"2007","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.ajog.2009.06.002_bib15","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S1359-6101(99)00025-8","article-title":"TGF-B signaling by Smad proteins","volume":"11","author":"Miyazono","year":"2000","journal-title":"Cytokine Growth Factor Rev"},{"key":"10.1016\/j.ajog.2009.06.002_bib16","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.ajog.2004.07.013","article-title":"Expression of matrix metalloproteinase-3 in the rat cervix during pregnancy and in response to Prostaglandin E2","volume":"192","author":"Chien","year":"2005","journal-title":"Am J Obstet Gynecol"},{"year":"2006","series-title":"Preterm birth: causes, consequences, and prevention","author":"Behrman","key":"10.1016\/j.ajog.2009.06.002_bib17"},{"key":"10.1016\/j.ajog.2009.06.002_bib18","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/0002-9378(83)90446-5","article-title":"Ripening of the human uterine cervix related to changes in collagen, glycosaminoglycans, and collagenolytic activity","volume":"147","author":"Uldbjerg","year":"1983","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2009.06.002_bib19","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1159\/000293296","article-title":"Mechanical properties of the pregnant human uterine cervix use of an instrument to measure the index of cervical distensibility","volume":"29","author":"Cabrol","year":"1990","journal-title":"Gynecol Obstet Invest"},{"key":"10.1016\/j.ajog.2009.06.002_bib20","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0925-4439(98)00005-2","article-title":"Differential expressions of mRNA for proteoglycans, collagens and transforming growth factor-beta in the human cervix during pregnancy and involution","volume":"1406","author":"Westergren-Thorsson","year":"1998","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.ajog.2009.06.002_bib21","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1515\/JPM.1999.006","article-title":"Changes in the cervical extracellular matrix during pregnancy and parturition","volume":"27","author":"Winkler","year":"1999","journal-title":"J Perinat Med"},{"key":"10.1016\/j.ajog.2009.06.002_bib22","doi-asserted-by":"crossref","first-page":"2491","DOI":"10.1093\/carcin\/bgm195","article-title":"The type III TGF-beta receptor signals through both Smad3 and the p38 MAP kinase pathways to contribute to inhibition of cell proliferation","volume":"28","author":"You","year":"2007","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.ajog.2009.06.002_bib23","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1210\/endo.140.6.6785","article-title":"Complex Interactions between sex steroids and cytokines in the human pregnant myometrium: evidence for an autocrine signaling system at term","volume":"140","author":"Hatthachote","year":"1999","journal-title":"Endocrinology"},{"key":"10.1016\/j.ajog.2009.06.002_bib24","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1210\/endo-125-4-1951","article-title":"Transforming growth factor-\u03b2 promotes differentiation of ovarian thecal-interstitial cells but inhibits androgen production","volume":"125","author":"Magoffin","year":"1989","journal-title":"Endocrinology"},{"key":"10.1016\/j.ajog.2009.06.002_bib25","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/S0039-128X(99)00048-3","article-title":"Progesterone and transforming growth factor-beta coordinately regulate suppression of endometrial matrix metalloproteinases in a model of experimental endometriosis","volume":"64","author":"Bruner","year":"1999","journal-title":"Steroids"},{"issue":"Pt 2","key":"10.1016\/j.ajog.2009.06.002_bib26","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1113\/jphysiol.2003.050179","article-title":"Elasticity in extracellular matrix \u201cshape modules\u201d of tendon, cartilage, etc","volume":"553","author":"Scott","year":"2003","journal-title":"J Physiol"},{"key":"10.1016\/j.ajog.2009.06.002_bib27","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1152\/physrev.00031.2003","article-title":"Role of extracellular matrix in adaptation of tendon and skeletal muscle to mechanical loading","volume":"84","author":"Kjaer","year":"2004","journal-title":"Physiol Rev"},{"key":"10.1016\/j.ajog.2009.06.002_bib28","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1055\/s-2006-956777","article-title":"Dynamics of cervical remodeling during pregnancy and parturition: mechanisms and current concepts","volume":"25","author":"Word","year":"2007","journal-title":"Semin Reprod Med"},{"key":"10.1016\/j.ajog.2009.06.002_bib29","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0950-3552(05)80226-3","article-title":"The physiology of cervical ripening and cervical dilation and the effect of abortifacient drugs","volume":"4","author":"Uldbjerg","year":"1990","journal-title":"Baillieres Clin Obstet Gynaecol"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000293780900622X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000293780900622X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T10:31:57Z","timestamp":1757586717000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000293780900622X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["S000293780900622X"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2009.06.002","relation":{},"ISSN":["0002-9378"],"issn-type":[{"type":"print","value":"0002-9378"}],"subject":[],"published":{"date-parts":[[2009,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of transforming growth factor \u03b2 in cervical remodeling within the rat cervix","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2009.06.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}