{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T18:08:38Z","timestamp":1773252518596,"version":"3.50.1"},"reference-count":20,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1016\/j.ajog.2011.07.002","type":"journal-article","created":{"date-parts":[[2011,7,24]],"date-time":"2011-07-24T11:49:07Z","timestamp":1311508147000},"page":"533.e1-533.e3","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"title":["Outcome following high-dose methotrexate in pregnancies misdiagnosed as ectopic"],"prefix":"10.1016","volume":"205","author":[{"given":"Laila","family":"Nurmohamed","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myla E.","family":"Moretti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tal","family":"Schechter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrienne","family":"Einarson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon V.","family":"Lavigne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aida","family":"Erebara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gideon","family":"Koren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaron","family":"Finkelstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2011.07.002_bib1","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.fertnstert.2006.11.005","article-title":"Care pathways for ectopic pregnancy: a population-based cost-effectiveness analysis","volume":"87","author":"Seror","year":"2007","journal-title":"Fertil Steril"},{"issue":"no. SS-6","key":"10.1016\/j.ajog.2011.07.002_bib2","first-page":"73","article-title":"Surveillance for ectopic pregnancy\u2013United States, 1970-1989","volume":"42","author":"Goldner","year":"1993","journal-title":"MMWR"},{"key":"10.1016\/j.ajog.2011.07.002_bib3","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1097\/AOG.0b013e3181d0c328","article-title":"Trends in the diagnosis and treatment of ectopic pregnancy in the United States","volume":"115","author":"Hoover","year":"2010","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2011.07.002_bib4","first-page":"1104","article-title":"Prenatal diagnosis of methotrexate embryopathy","volume":"101","author":"Chapa","year":"2003","journal-title":"Obstet and Gynecol"},{"key":"10.1016\/j.ajog.2011.07.002_bib5","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1038\/sj.jp.7211563","article-title":"Failed methotrexate termination of pregnancy: a case report","volume":"26","author":"Goffman","year":"2006","journal-title":"J Perinatol"},{"key":"10.1016\/j.ajog.2011.07.002_bib6","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1002\/bdra.20199","article-title":"A case of methotrexate embryopathy with holoprosencephaly, expanding the phenotype","volume":"76","author":"Seidahmed","year":"2006","journal-title":"Clin Molec Teratol"},{"issue":"5 Suppl","key":"10.1016\/j.ajog.2011.07.002_bib7","first-page":"S206","article-title":"Medical treatment of ectopic pregnancy","year":"2008","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ajog.2011.07.002_bib8","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1002\/tera.1420470605","article-title":"Clinical teratology counselling and consultation case report: Low dose methotrexate exposure in the early weeks of pregnancy","volume":"47","author":"Feldkamp","year":"1993","journal-title":"Teratology"},{"key":"10.1016\/j.ajog.2011.07.002_bib9","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1093\/humrep\/dep397","article-title":"Economic evaluation of diagnosing and excluding ectopic pregnancy","volume":"25","author":"Wedderburn","year":"2010","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ajog.2011.07.002_bib10","first-page":"505","article-title":"Presumed diagnosis of ectopic pregnancy","volume":"100","author":"Barnhart","year":"2002","journal-title":"Obstet and Gynecol"},{"key":"10.1016\/j.ajog.2011.07.002_bib11","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.annemergmed.2008.12.013","article-title":"Emergency ultrasound guidelines","volume":"53","year":"2009","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.ajog.2011.07.002_bib12","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1016\/j.annemergmed.2010.06.563","article-title":"Emergency physician ultrasonography for evaluating patients at risk for ectopic pregnancy: a meta-analysis","volume":"56","author":"Stein","year":"2010","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.ajog.2011.07.002_bib13","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.annemergmed.2005.08.023","article-title":"Ultrasonography in community emergency departments in the United States: access to ultrasonography performed by consultants and status of emergency-performed ultrasonography","volume":"47","author":"Moore","year":"2006","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.ajog.2011.07.002_bib14","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/ajmg.a.20503","article-title":"Methotrexate\/misoprostol embryopathy: report of four cases resulting from failed medical abortion","volume":"123A","author":"Adam","year":"2003","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.ajog.2011.07.002_bib15","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/S1701-2163(16)30422-4","article-title":"Methotrexate embryopathy in a surviving intrauterine fetus after presumed diagnosis of ectopic pregnancy: case report","volume":"26","author":"Addar","year":"2004","journal-title":"J Obstet Gynecol Canada"},{"key":"10.1016\/j.ajog.2011.07.002_bib16","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.ijgo.2007.05.039","article-title":"Methotrexate embryopathy after therapy for misdiagnosed ectopic pregnancy","volume":"99","author":"Usta","year":"2007","journal-title":"Int J Gynecol Obstet"},{"key":"10.1016\/j.ajog.2011.07.002_bib17","first-page":"1","article-title":"Estimated pregnancy rates by outcome for the United States, 1990-2004","volume":"56","author":"Ventura","year":"2008","journal-title":"National Vital Statistics Reports"},{"key":"10.1016\/j.ajog.2011.07.002_bib18","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1056\/NEJMcp0810384","article-title":"Ectopic pregnancy","volume":"361","author":"Barnhart","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajog.2011.07.002_bib19","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1016\/j.fertnstert.2009.10.032","article-title":"Compliance with methotrexate therapy for presumed ectopic pregnancy in an inner-city population","volume":"94","author":"Jaspan","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ajog.2011.07.002_bib20","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1093\/qjmed\/92.10.551","article-title":"The effects of methotrexate on pregnancy, fertility and lactation","volume":"92","author":"Lloyd","year":"1999","journal-title":"QJM"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937811009033?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937811009033?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T10:41:41Z","timestamp":1757587301000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937811009033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["S0002937811009033"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2011.07.002","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2011,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Outcome following high-dose methotrexate in pregnancies misdiagnosed as ectopic","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2011.07.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}