{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T15:04:09Z","timestamp":1788879849913,"version":"build-2803163510"},"reference-count":82,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1016\/j.ajog.2014.03.028","type":"journal-article","created":{"date-parts":[[2014,3,17]],"date-time":"2014-03-17T22:20:27Z","timestamp":1395094827000},"page":"91-117","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":111,"title":["Association between maternal body mass index and congenital heart defects in offspring: a systematic review"],"prefix":"10.1016","volume":"211","author":[{"given":"Guang-ju","family":"Cai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing-xing","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2014.03.028_bib1","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.amepre.2011.10.026","article-title":"Obesity and severe obesity forecasts through 2030","volume":"42","author":"Finkelstein","year":"2012","journal-title":"Am J Prev Med"},{"key":"10.1016\/j.ajog.2014.03.028_bib2","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.siny.2009.10.003","article-title":"Management of maternal obesity prior to and during pregnancy","volume":"15","author":"Shaikh","year":"2010","journal-title":"Semin Fetal Neonatal Med"},{"key":"10.1016\/j.ajog.2014.03.028_bib3","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1001\/jama.2009.2014","article-title":"Prevalence and trends in obesity among US adults, 1999-2008","volume":"303","author":"Flegal","year":"2010","journal-title":"JAMA"},{"key":"10.1016\/j.ajog.2014.03.028_bib4","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/1471-2393-10-56","article-title":"The risk of adverse pregnancy outcomes in women who are overweight or obese","volume":"10","author":"Athukorala","year":"2010","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.ajog.2014.03.028_bib5","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1038\/sj.ijo.0801670","article-title":"Maternal obesity and pregnancy outcome: a study of 287,213 pregnancies in London","volume":"25","author":"Sebire","year":"2001","journal-title":"Int J Obes Relat Metab Disord"},{"key":"10.1016\/j.ajog.2014.03.028_bib6","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s00404-006-0219-y","article-title":"Effect of prepregnancy body mass index categories on obstetrical and neonatal outcomes","volume":"275","author":"Abenhaim","year":"2007","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.ajog.2014.03.028_bib7","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/j.ajog.2003.09.058","article-title":"Obesity, obstetric complications and cesarean delivery rate-a population-based screening study","volume":"190","author":"Weiss","year":"2004","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2014.03.028_bib8","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1001\/jama.2009.113","article-title":"Maternal overweight and obesity and the risk of congenital anomalies a systematic review and meta-analysis","volume":"301","author":"Stothard","year":"2009","journal-title":"JAMA"},{"key":"10.1016\/j.ajog.2014.03.028_bib9","doi-asserted-by":"crossref","first-page":"F378","DOI":"10.1136\/adc.2009.170928","article-title":"Fetal and perinatal consequences of maternal obesity","volume":"96","author":"Vasudevan","year":"2011","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.ajog.2014.03.028_bib10","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1111\/j.1479-828X.2008.00860.x","article-title":"Maternal Obesity and pregnancy complications: a review","volume":"48","author":"Ramachenderan","year":"2008","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"10.1016\/j.ajog.2014.03.028_bib11","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1479-828X.2008.00934.x","article-title":"Association of maternal pre-pregnancy weight with birth defects: evidence from a case-control study in Western Australia","volume":"49","author":"Oddy","year":"2009","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"10.1016\/j.ajog.2014.03.028_bib12","doi-asserted-by":"crossref","first-page":"E32","DOI":"10.1542\/peds.107.3.e32","article-title":"Racial and temporal variations in the prevalence of heart defects","volume":"107","author":"Botto","year":"2001","journal-title":"Pediatrics"},{"key":"10.1016\/j.ajog.2014.03.028_bib13","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1093\/oxfordjournals.aje.a113979","article-title":"Congenital heart disease: prevalence at livebirth: the Baltimore-Washington Infant Study","volume":"121","author":"Ferencz","year":"1985","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.ajog.2014.03.028_bib14","first-page":"375","article-title":"Report of the New England Regional Infant Cardiac Program","volume":"65","author":"Fyler","year":"1980","journal-title":"Pediatrics"},{"key":"10.1016\/j.ajog.2014.03.028_bib15","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1016\/S0735-1097(02)01886-7","article-title":"The incidence of congenital heart disease","volume":"39","author":"Hoffman","year":"2002","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.ajog.2014.03.028_bib16","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1016\/S0735-1097(01)01272-4","article-title":"Task force 1: the changing profile of congenital heart disease in adult life","volume":"37","author":"Warnes","year":"2001","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.ajog.2014.03.028_bib17","series-title":"Congenital heart disease-Selected aspects","article-title":"Congenital heart defects-A review","author":"Rao","year":"2012"},{"key":"10.1016\/j.ajog.2014.03.028_bib18","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1016\/j.jacc.2011.08.025","article-title":"Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis","volume":"58","author":"Van der Linde","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.ajog.2014.03.028_bib19","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1053\/j.pcsu.2010.02.005","article-title":"The challenge of congenital heart disease worldwide: epidemiologic and demographic facts","volume":"13","author":"Bernier","year":"2010","journal-title":"Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu"},{"key":"10.1016\/j.ajog.2014.03.028_bib20","first-page":"1344","article-title":"Outcome of congenital heart defects-a population based study","volume":"89","author":"Meberg","year":"2000","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.ajog.2014.03.028_bib21","series-title":"Obesity: preventing and managing the global epidemic. WHO Technical Report Series no. 894","year":"2000"},{"key":"10.1016\/j.ajog.2014.03.028_bib22","doi-asserted-by":"crossref","first-page":"b2535","DOI":"10.1136\/bmj.b2535","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"338","author":"Moher","year":"2009","journal-title":"BMJ"},{"key":"10.1016\/j.ajog.2014.03.028_bib23","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.ajog.2014.03.028_bib24","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.ajog.2007.03.027","article-title":"Maternal obesity and risk of stillbirth: a metaanalysis","volume":"197","author":"Chu","year":"2007","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2014.03.028_bib25","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0002-9378(94)70224-1","article-title":"Are obese women at higher risk for producing malformed offspring?","volume":"170","author":"Waller","year":"1994","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2014.03.028_bib26","doi-asserted-by":"crossref","first-page":"51.e1","DOI":"10.1016\/j.ajog.2009.08.005","article-title":"Association between prepregnancy body mass index and congenital heart defects","volume":"202","author":"Gilboa","year":"2010","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2014.03.028_bib27","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1136\/heartjnl-2011-300822","article-title":"Combined adverse effects of maternal smoking and high body mass index on heart development in offspring: evidence for interaction?","volume":"98","author":"Baardman","year":"2012","journal-title":"Heart"},{"key":"10.1016\/j.ajog.2014.03.028_bib28","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.3945\/ajcn.2009.28865","article-title":"Maternal obesity and congenital heart defects: a population-based study","volume":"91","author":"Mills","year":"2010","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.ajog.2014.03.028_bib29","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1038\/oby.2003.146","article-title":"Maternal obesity and infant heart defects","volume":"11","author":"Cedergren","year":"2003","journal-title":"Obes Res"},{"key":"10.1016\/j.ajog.2014.03.028_bib30","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.ijgo.2008.05.005","article-title":"Maternal obesity and neonatal congenital cardiovascular defects","volume":"102","author":"Khalil","year":"2008","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.ajog.2014.03.028_bib31","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1542\/peds.111.S1.1152","article-title":"Maternal obesity and risk for birth defects","volume":"111","author":"Watkins","year":"2003","journal-title":"Pediatrics"},{"key":"10.1016\/j.ajog.2014.03.028_bib32","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1097\/00001648-200107000-00014","article-title":"Maternal prepregnancy weight and congenital heart defects in offspring","volume":"12","author":"Watkins","year":"2001","journal-title":"Epidemiology"},{"key":"10.1016\/j.ajog.2014.03.028_bib33","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1111\/j.1464-5491.2005.01492.x","article-title":"Pre-gestational maternal body mass index predicts an increased risk of congenital malformations in infants of mothers with gestational diabetes","volume":"22","author":"Mart\u00ednez-Fr\u00edas","year":"2005","journal-title":"Diabet Med"},{"key":"10.1016\/j.ajog.2014.03.028_bib34","first-page":"1","article-title":"Prepregnancy body mass index and congenital heart defects among offspring: a population-based study","volume":"8","author":"Madsen","year":"2012","journal-title":"Congenit Heart Dis"},{"key":"10.1016\/j.ajog.2014.03.028_bib35","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1001\/archpedi.161.8.745","article-title":"Prepregnancy obesity as a risk factor for structural birth defects","volume":"61","author":"Waller","year":"2007","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.ajog.2014.03.028_bib36","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1097\/EDE.0b013e3181761fa3","article-title":"Prepregnant obesity and risks of selected birth defects in offspring","volume":"19","author":"Shaw","year":"2008","journal-title":"Epidemiology"},{"key":"10.1016\/j.ajog.2014.03.028_bib37","doi-asserted-by":"crossref","first-page":"12","DOI":"10.5271\/sjweh.641","article-title":"Risk factors for cardiovascular malformation-a study based on prospectively collected data","volume":"28","author":"Cedergren","year":"2002","journal-title":"Scand J Work Environ Health"},{"key":"10.1016\/j.ajog.2014.03.028_bib38","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1097\/00001648-200011000-00013","article-title":"A\u00a0prospective study of the risk of congenital defects associated with maternal obesity and diabetes mellitus","volume":"11","author":"Moore","year":"2000","journal-title":"Epidemiology"},{"key":"10.1016\/j.ajog.2014.03.028_bib39","first-page":"695","article-title":"Association between maternal obesity and fetal cardiac malformations in African Americans","volume":"94","author":"Mikhail","year":"2002","journal-title":"J\u00a0Natl Med Assoc"},{"key":"10.1016\/j.ajog.2014.03.028_bib40","first-page":"218","article-title":"Congenital malformations and environmental influences in pregnancy","volume":"23","author":"Richards","year":"1969","journal-title":"Br J Prev Soc Med"},{"key":"10.1016\/j.ajog.2014.03.028_bib41","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1111\/j.1651-2227.2002.tb01699.x","article-title":"Geographic variations in possible risk factors for severe cardiac malformations","volume":"91","author":"Cedergren","year":"2002","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.ajog.2014.03.028_bib42","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/s00125-004-1337-3","article-title":"In human gestational diabetes mellitus congenital malformations are related to pre-pregnancy body mass index and to severity of diabetes","volume":"47","author":"Garc\u00eda-Patterson","year":"2004","journal-title":"Diabetologia"},{"key":"10.1016\/j.ajog.2014.03.028_bib43","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1046\/j.1365-3016.2000.00274.x","article-title":"Maternal height and prepregnancy body mass index as risk factors for selected congenital anomalies","volume":"14","author":"Shaw","year":"2000","journal-title":"Paediatr Perinat Epidemiol"},{"key":"10.1016\/j.ajog.2014.03.028_bib44","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1002\/bdra.20620","article-title":"Maternal obesity and morbid obesity: the risk for birth defects in the offspring","volume":"88","author":"Blomberg","year":"2010","journal-title":"Birth Defects Res A Clin Mol Teratol"},{"key":"10.1016\/j.ajog.2014.03.028_bib45","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.ejogrb.2005.07.006","article-title":"Obstetric outcome of 6346 pregnancies with infants affected by congenital heart defects","volume":"125","author":"Cedergren","year":"2006","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ajog.2014.03.028_bib46","first-page":"325","article-title":"Prepregnancy obesity and birth defects in Rhode Island","volume":"93","author":"Arias","year":"2010","journal-title":"Med Health R I"},{"key":"10.1016\/j.ajog.2014.03.028_bib47","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1093\/ajcn\/87.6.1750","article-title":"Combined associations of prepregnancy body mass index and gestational weight gain with the outcome of pregnancy","volume":"87","author":"Nohr","year":"2008","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.ajog.2014.03.028_bib48","first-page":"339","article-title":"Maternal obesity: a potential source of error in sonographic prenatal diagnosis","volume":"76","author":"Wolfe","year":"1990","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2014.03.028_bib49","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1038\/sj.ijo.0802759","article-title":"The impact of maternal obesity on midtrimester sonographic visualization of fetal cardiac and craniospinal structures","volume":"8","author":"Hendler","year":"2004","journal-title":"Int J Obes Relat Metab Disord"},{"key":"10.1016\/j.ajog.2014.03.028_bib50","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.7863\/jum.2005.24.9.1205","article-title":"Suboptimal second-trimester ultrasonographic visualization of the fetal heart in obese women: should we repeat the examination?","volume":"24","author":"Hendler","year":"2005","journal-title":"J\u00a0Ultrasound Med"},{"key":"10.1016\/j.ajog.2014.03.028_bib51","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1079\/PHN2001322","article-title":"Validity of self-reported height and weight in 4808 EPIC-Oxford participants","volume":"5","author":"Spencer","year":"2002","journal-title":"Public Health Nutr"},{"key":"10.1016\/j.ajog.2014.03.028_bib52","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1097\/00001648-199003000-00011","article-title":"Body mass definitions of obesity: sensitivity and specificity using self-reported weight and height","volume":"1","author":"Anieto-Garcia","year":"1990","journal-title":"Epidemiology"},{"key":"10.1016\/j.ajog.2014.03.028_bib53","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1093\/ajcn\/52.6.1125","article-title":"Self-reported weight and height","volume":"52","author":"Rowland","year":"1990","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.ajog.2014.03.028_bib54","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s10995-006-0157-0","article-title":"Validity of self-reported height and weight in women of reproductive age","volume":"11","author":"Brunner Huber","year":"2006","journal-title":"Matern Child Health J"},{"key":"10.1016\/j.ajog.2014.03.028_bib55","doi-asserted-by":"crossref","first-page":"237.e1","DOI":"10.1016\/j.ajog.2008.06.028","article-title":"Diabetes mellitus and birth defects","volume":"199","author":"Correa","year":"2008","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2014.03.028_bib56","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1542\/peds.85.1.1","article-title":"Diabetes mellitus during pregnancy and the risks of specific birth defects: a population based case-control study","volume":"85","author":"Becerra","year":"1990","journal-title":"Pediatrics"},{"key":"10.1016\/j.ajog.2014.03.028_bib57","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1023\/A:1021879504372","article-title":"Congenital malformations in offspring of diabetic mothers: animal and human studies","volume":"4","author":"Eriksson","year":"2003","journal-title":"Rev Endocr Metab Disord"},{"key":"10.1016\/j.ajog.2014.03.028_bib58","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/1475-2840-6-34","article-title":"Maternal diabetes induces congenital heart defects in mice by altering the expression of genes involved in cardiovascular development","volume":"6","author":"Kumar","year":"2007","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.ajog.2014.03.028_bib59","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s00246-003-0538-8","article-title":"Congenital heart disease in infants of diabetic mothers: echocardiographic study","volume":"25","author":"Abu-Sulaiman","year":"2004","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.ajog.2014.03.028_bib60","first-page":"3","article-title":"Maternal insulin-dependent diabetes and congenital malformations in the newborn","volume":"42","author":"Kalaidzhieva","year":"2003","journal-title":"Akush Ginekol (Sofiia)"},{"key":"10.1016\/j.ajog.2014.03.028_bib61","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1111\/j.1464-5491.2005.01477.x","article-title":"Risk of specific congenital abnormalities in offspring of women with diabetes","volume":"22","author":"Nielsen","year":"2005","journal-title":"Diabet Med"},{"key":"10.1016\/j.ajog.2014.03.028_bib62","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.2337\/dc06-2559a","article-title":"Maternal obesity and risk of gestational diabetes mellitus","volume":"30","author":"Chu","year":"2007","journal-title":"Diabetes Care"},{"key":"10.1016\/j.ajog.2014.03.028_bib63","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.2337\/dc06-2544","article-title":"Effect of BMI on life-time risk for diabetes in the US","volume":"30","author":"Narayan","year":"2007","journal-title":"Diabetes Care"},{"key":"10.1016\/j.ajog.2014.03.028_bib64","first-page":"40","article-title":"Does maternal obesity increase the risk of fetal abnormalities? Analysis of 20,248 newborn infants of\u00a0the Mainz Birth Register for detecting congenital abnormalities","volume":"19","author":"Queisser-Luft","year":"1998","journal-title":"Ultraschall Med"},{"key":"10.1016\/j.ajog.2014.03.028_bib65","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.pcl.2004.01.003","article-title":"Infants of diabetic mothers","volume":"51","author":"Nold","year":"2004","journal-title":"Pediatr Clin North Am"},{"key":"10.1016\/j.ajog.2014.03.028_bib66","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1203\/00006450-199503000-00015","article-title":"Correlations between maternal metabolism and deranged development in the offspring of normal and diabetic rats","volume":"37","author":"Styrud","year":"1995","journal-title":"Pediatr Res"},{"key":"10.1016\/j.ajog.2014.03.028_bib67","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/bdra.20341","article-title":"Exposure of neural crest cells to elevated glucose leads to congenital heart defects, an\u00a0effect that can be prevented by N-acetylcysteine","volume":"79","author":"Roest","year":"2007","journal-title":"Birth Defects Res A Clin Mol\u00a0Teratol"},{"key":"10.1016\/j.ajog.2014.03.028_bib68","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/BF00400671","article-title":"High glucose concentration inhibits migration of rat cranial neural crest cells in\u00a0vitro","volume":"39","author":"Suzuki","year":"1996","journal-title":"Diabetologia"},{"key":"10.1016\/j.ajog.2014.03.028_bib69","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1242\/dev.127.9.1869","article-title":"Migration of cardiac neural crest cells in Splotch embryos","volume":"127","author":"Epstein","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.ajog.2014.03.028_bib70","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1007\/s10654-004-2253-z","article-title":"Body mass index and serum folate in childbearing age women","volume":"19","author":"Mojtabai","year":"2004","journal-title":"Eur J Epidemiol"},{"key":"10.1016\/j.ajog.2014.03.028_bib71","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0140-6736(91)90133-A","article-title":"Prevention of neural tube defects: results of the Medical Research Council Vitamin study","volume":"338","year":"1991","journal-title":"Lancet"},{"key":"10.1016\/j.ajog.2014.03.028_bib72","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1056\/NEJM199212243272602","article-title":"Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation","volume":"327","author":"Czeizel","year":"1992","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ajog.2014.03.028_bib73","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1542\/peds.98.5.911","article-title":"Periconceptional multivitamin use and the occurrence of conotruncal heart defects: results from a population-based case-control study","volume":"98","author":"Botto","year":"1996","journal-title":"Pediatrics"},{"key":"10.1016\/j.ajog.2014.03.028_bib74","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1093\/oxfordjournals.aje.a010291","article-title":"Occurrence of congenital heart defects in relation to maternal multivitamin use","volume":"151","author":"Botto","year":"2000","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.ajog.2014.03.028_bib75","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1002\/bdra.20086","article-title":"Hungarian cohort controlled trial of periconceptional multivitamin supplementation shows a reduction in certain congenital abnormalities","volume":"70","author":"Czeizel","year":"2004","journal-title":"Birth Defects Res A Clin Mol Teratol"},{"key":"10.1016\/j.ajog.2014.03.028_bib76","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1002\/ajmg.1320590428","article-title":"Maternal periconceptional use of multivitamins and reduced risk for conotruncal heart defects and limb deficiencies among offspring","volume":"59","author":"Shaw","year":"1995","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.ajog.2014.03.028_bib77","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1093\/eurheartj\/ehp479","article-title":"Protective effect of periconceptional folic acid supplements on the risk of congenital heart defects: a registry-based case-control study in the northern Netherlands","volume":"31","author":"Van Beynum","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ajog.2014.03.028_bib78","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1097\/01.AOG.0000151988.84346.3e","article-title":"Greater maternal weight and the ongoing risk of neural tube defects after folic acid flour fortification","volume":"105","author":"Ray","year":"2005","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2014.03.028_bib79","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.7863\/jum.2009.28.8.1025","article-title":"Maternal obesity limits the ultrasound evaluation of fetal anatomy","volume":"28","author":"Dashe","year":"2009","journal-title":"J\u00a0Ultrasound Med"},{"key":"10.1016\/j.ajog.2014.03.028_bib80","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1016\/j.ajog.2004.03.064","article-title":"Does advanced ultrasound equipment improve the adequacy of ultrasound visualization of fetal cardiac structures in the obese gravid woman?","volume":"190","author":"Hendler","year":"2004","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2014.03.028_bib81","doi-asserted-by":"crossref","first-page":"659","DOI":"10.7863\/jum.1993.12.11.659","article-title":"Fetal echocardiography: factors that influence imaging of the fetal heart during the second trimester of pregnancy","volume":"12","author":"DeVore","year":"1993","journal-title":"J\u00a0Ultrasound Med"},{"key":"10.1016\/j.ajog.2014.03.028_bib82","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1002\/pd.2923","article-title":"Fetal heart disease and interruption of pregnancy: factors influencing the parental decision-making process","volume":"32","author":"Chenni","year":"2012","journal-title":"Prenat Diagn"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937814002385?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937814002385?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T10:57:55Z","timestamp":1757588275000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937814002385"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":82,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["S0002937814002385"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2014.03.028","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2014,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between maternal body mass index and congenital heart defects in offspring: a systematic review","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2014.03.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}