{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T18:52:21Z","timestamp":1792608741779,"version":"4.5.0"},"reference-count":79,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["P51OD010425"],"award-info":[{"award-number":["P51OD010425"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21AI09222"],"award-info":[{"award-number":["R21AI09222"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AI112619"],"award-info":[{"award-number":["R01AI112619"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["GAPPS 12007"],"award-info":[{"award-number":["GAPPS 12007"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AI100989"],"award-info":[{"award-number":["R01AI100989"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K08AI067910"],"award-info":[{"award-number":["K08AI067910"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30HD002274"],"award-info":[{"award-number":["P30HD002274"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U54 HD083091"],"award-info":[{"award-number":["U54 HD083091"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000912","name":"March of Dimes Foundation","doi-asserted-by":"publisher","award":["21-FY08-562"],"award-info":[{"award-number":["21-FY08-562"]}],"id":[{"id":"10.13039\/100000912","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.ajog.2015.08.028","type":"journal-article","created":{"date-parts":[[2015,8,15]],"date-time":"2015-08-15T16:50:42Z","timestamp":1439657442000},"page":"830.e1-830.e19","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":135,"title":["Uterine overdistention induces preterm labor mediated by inflammation: observations in pregnant women and nonhuman primates"],"prefix":"10.1016","volume":"213","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6939-7224","authenticated-orcid":false,"given":"Kristina M.","family":"Adams Waldorf","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aarthi R.","family":"Mohan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger C.","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Ngo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ananya","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4921-3982","authenticated-orcid":false,"given":"Jesse","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aasthaa","family":"Bansal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Paolella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bronwen R.","family":"Herbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suren R.","family":"Sooranna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Michael","family":"Gough","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cliff","family":"Astley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Vogel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey E.","family":"Baldessari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodor K.","family":"Bammler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"MacDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael G.","family":"Gravett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lakshmi","family":"Rajagopal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark R.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2015.08.028_bib1","first-page":"1","article-title":"Births: preliminary data for 2013","volume":"63","author":"Hamilton","year":"2013","journal-title":"Div Vital Stat"},{"key":"10.1016\/j.ajog.2015.08.028_bib2","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1530\/REP-09-0260","article-title":"Mechanical stretch regulates hypertrophic phenotype of the myometrium during pregnancy","volume":"139","author":"Shynlova","year":"2010","journal-title":"Reproduction"},{"key":"10.1016\/j.ajog.2015.08.028_bib3","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1095\/biolreprod.105.048124","article-title":"Myometrial apoptosis: activation of the caspase cascade in the pregnant rat myometrium at midgestation","volume":"74","author":"Shynlova","year":"2006","journal-title":"Biol Reprod"},{"key":"10.1016\/j.ajog.2015.08.028_bib4","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/S0002-9378(96)80051-2","article-title":"The preterm prediction study: risk factors in twin gestations. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network","volume":"175","author":"Goldenberg","year":"1996","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2015.08.028_bib5","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/0029-7844(94)00455-M","article-title":"The origin and outcome of preterm twin pregnancies","volume":"85","author":"Gardner","year":"1995","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2015.08.028_bib6","first-page":"117","article-title":"Polyhydramnion: a clinical study","volume":"67","author":"Kirkinen","year":"1978","journal-title":"Ann Chir Gynaecol"},{"key":"10.1016\/j.ajog.2015.08.028_bib7","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/S0015-0282(97)81506-3","article-title":"Unicornuate uterus and rudimentary horn","volume":"68","author":"Heinonen","year":"1997","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ajog.2015.08.028_bib8","doi-asserted-by":"crossref","first-page":"41","DOI":"10.2174\/1570161033386745","article-title":"Biomechanical stress-induced signaling in smooth muscle cells: an update","volume":"1","author":"Shaw","year":"2003","journal-title":"Curr Vasc Pharmacol"},{"key":"10.1016\/j.ajog.2015.08.028_bib9","first-page":"661","article-title":"Decidual morphology and F prostaglandin in amniotic fluid in stretch-induced abortion","volume":"64","author":"Manabe","year":"1984","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2015.08.028_bib10","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1097\/AOG.0b013e3181dec6d0","article-title":"Labor induction with a Foley balloon inflated to 30 mL compared with 60 mL: a randomized controlled trial","volume":"115","author":"Delaney","year":"2010","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2015.08.028_bib11","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/0090-6980(83)90119-3","article-title":"Effect of indomethacin on stretch-induced uterine activity in the post-partum","volume":"25","author":"Manabe","year":"1983","journal-title":"Prostaglandins"},{"key":"10.1016\/j.ajog.2015.08.028_bib12","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0140-6736(08)60074-4","article-title":"Epidemiology and causes of preterm birth","volume":"371","author":"Goldenberg","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.ajog.2015.08.028_bib13","doi-asserted-by":"crossref","first-page":"5398","DOI":"10.1210\/endo.138.12.5624","article-title":"Expression of connexin-43 and connexin-26 in the rat myometrium during pregnancy and labor is differentially regulated by mechanical and hormonal signals","volume":"138","author":"Ou","year":"1997","journal-title":"Endocrinology"},{"key":"10.1016\/j.ajog.2015.08.028_bib14","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1469-445X.2000.tb00012.x","article-title":"The role of oxytocin and regulation of uterine oxytocin receptors in pregnant marsupials","volume":"85","author":"Parry","year":"2000","journal-title":"Exp Physiol"},{"key":"10.1016\/j.ajog.2015.08.028_bib15","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1177\/1933719112446084","article-title":"Physiologic uterine inflammation and labor onset: integration of endocrine and mechanical signals","volume":"20","author":"Shynlova","year":"2013","journal-title":"Reprod Sci"},{"key":"10.1016\/j.ajog.2015.08.028_bib16","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1038\/cmi.2014.39","article-title":"Stretch-induced human myometrial cytokines enhance immune cell recruitment via endothelial activation","volume":"12","author":"Lee","year":"2015","journal-title":"Cell Mol Immunol"},{"key":"10.1016\/j.ajog.2015.08.028_bib17","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1210\/en.2011-1506","article-title":"Stretch and inflammatory cytokines drive myometrial chemokine expression via NF-kappaB activation","volume":"153","author":"Hua","year":"2012","journal-title":"Endocrinology"},{"key":"10.1016\/j.ajog.2015.08.028_bib18","first-page":"514","article-title":"Endocrine and paracrine regulation of birth at\u00a0term and preterm","volume":"21","author":"Challis","year":"2000","journal-title":"Endocr Rev"},{"key":"10.1016\/j.ajog.2015.08.028_bib19","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/0039-128X(80)90035-5","article-title":"Serum progesterone and corpus luteum function in pregnant pigtailed monkeys (Macaca nemestrina)","volume":"36","author":"Chandrashekar","year":"1980","journal-title":"Steroids"},{"key":"10.1016\/j.ajog.2015.08.028_bib20","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1210\/jcem-58-4-629","article-title":"Daily hormonal changes in the maternal, fetal, and amniotic fluid compartments before parturition in a primate species","volume":"58","author":"Walsh","year":"1984","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.ajog.2015.08.028_bib21","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1016\/0002-9378(94)90418-9","article-title":"An experimental model for intraamniotic infection and preterm labor in rhesus monkeys","volume":"171","author":"Gravett","year":"1994","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2015.08.028_bib22","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1152\/physiolgenomics.00181.2004","article-title":"Mechanical stretch is a highly selective regulator\u00a0of gene expression in human bladder smooth muscle cells","volume":"20","author":"Adam","year":"2004","journal-title":"Physiol Genomics"},{"key":"10.1016\/j.ajog.2015.08.028_bib23","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1165\/rcmb.2005-0326OC","article-title":"Cholinergic receptor and cyclic stretch-mediated inflammatory gene expression in intact ASM","volume":"34","author":"Kanefsky","year":"2006","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.ajog.2015.08.028_bib24","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1161\/HYPERTENSIONAHA.107.098046","article-title":"Gene\u00a0expression pattern in biomechanically stretched cardiomyocytes: evidence for a stretch-specific gene program","volume":"51","author":"Frank","year":"2008","journal-title":"Hypertension"},{"key":"10.1016\/j.ajog.2015.08.028_bib25","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1177\/1933719107310992","article-title":"Pretreatment with\u00a0toll-like receptor 4 antagonist inhibits lipopolysaccharide-induced preterm uterine contractility, cytokines, and prostaglandins in rhesus monkeys","volume":"15","author":"Adams Waldorf","year":"2008","journal-title":"Reprod Sci"},{"key":"10.1016\/j.ajog.2015.08.028_bib26","doi-asserted-by":"crossref","first-page":"e28972","DOI":"10.1371\/journal.pone.0028972","article-title":"Choriodecidual group B streptococcal inoculation induces fetal lung injury without intra-amniotic infection and preterm labor in Macaca nemestrina","volume":"6","author":"Adams Waldorf","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.ajog.2015.08.028_bib27","doi-asserted-by":"crossref","first-page":"e1003850","DOI":"10.1371\/journal.pcbi.1003850","article-title":"Linking myometrial physiology to intrauterine pressure; how tissue-level contractions create uterine contractions of labor","volume":"10","author":"Young","year":"2014","journal-title":"PLoS Computat Biol"},{"key":"10.1016\/j.ajog.2015.08.028_bib28","doi-asserted-by":"crossref","first-page":"e11037","DOI":"10.1371\/journal.pone.0011037","article-title":"Human uterine wall tension trajectories and the onset of parturition","volume":"5","author":"Sokolowski","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.ajog.2015.08.028_bib29","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.actbio.2007.04.009","article-title":"Mechanical and biochemical properties of human cervical tissue","volume":"4","author":"Myers","year":"2008","journal-title":"Acta Biomater"},{"key":"10.1016\/j.ajog.2015.08.028_bib30","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1471-0528.1992.tb14385.x","article-title":"Normal amniotic pressure throughout gestation","volume":"99","author":"Fisk","year":"1992","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.ajog.2015.08.028_bib31","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/BF01739765","article-title":"Mechanical properties of mammalian single smooth muscle cells, III: passive properties of pig detrusor and human a terme uterus cells","volume":"11","author":"Glerum","year":"1990","journal-title":"J\u00a0Muscle Res Cell Motil"},{"key":"10.1016\/j.ajog.2015.08.028_bib32","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.placenta.2010.06.010","article-title":"Differential host response to LPS variants in amniochorion and the TLR4\/MD-2 system in Macaca nemestrina","volume":"31","author":"Chang","year":"2010","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2015.08.028_bib33","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1093\/nar\/30.1.207","article-title":"Gene Expression Omnibus: NCBI gene expression and hybridization array data repository","volume":"30","author":"Edgar","year":"2002","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.ajog.2015.08.028_bib34","doi-asserted-by":"crossref","first-page":"R80","DOI":"10.1186\/gb-2004-5-10-r80","article-title":"Bioconductor: open software development for computational biology and bioinformatics","volume":"5","author":"Gentleman","year":"2004","journal-title":"Genome Biol"},{"key":"10.1016\/j.ajog.2015.08.028_bib35","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1093\/bioinformatics\/btq431","article-title":"A\u00a0framework for oligonucleotide microarray preprocessing","volume":"26","author":"Carvalho","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.ajog.2015.08.028_bib36","series-title":"Bioinformatics and computational biology solutions using R and Bioconductor","article-title":"Quality assessment of Affymetrix GeneChip data","year":"2005"},{"key":"10.1016\/j.ajog.2015.08.028_bib37","doi-asserted-by":"crossref","DOI":"10.1198\/004017008000000334","article-title":"Quality assessment for short oligonucleotide microarray data","volume":"50","author":"Brettschneider","year":"2008","journal-title":"Technometrics"},{"key":"10.1016\/j.ajog.2015.08.028_bib38","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1198\/016214504000000683","article-title":"A\u00a0model based background adjustment for oligonucleotide expression arrays","volume":"99","author":"Zhijin","year":"2004","journal-title":"J\u00a0Am Stat Assoc"},{"key":"10.1016\/j.ajog.2015.08.028_bib39","doi-asserted-by":"crossref","DOI":"10.2202\/1544-6115.1027","article-title":"Linear models and empirical Bayes methods for assessing differential expression in microarray experiments","volume":"3","author":"Smyth","year":"2004","journal-title":"Stat Appl Genet Mol Biol"},{"key":"10.1016\/j.ajog.2015.08.028_bib40","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1186\/1471-2105-7-261","article-title":"Empirical array quality weights in the analysis of microarray data","volume":"7","author":"Ritchie","year":"2006","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.ajog.2015.08.028_bib41","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0378-4274(01)00341-1","article-title":"Tissue specific changes in the expression of glutamate-cysteine ligase mRNAs in mice exposed to methylmercury","volume":"122","author":"Diaz","year":"2001","journal-title":"Toxicol Lett"},{"key":"10.1016\/j.ajog.2015.08.028_bib42","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1124\/mol.62.1.162","article-title":"Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam\u00a0metabolism","volume":"62","author":"Lin","year":"2002","journal-title":"Mol Pharmacol"},{"key":"10.1016\/j.ajog.2015.08.028_bib43","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1096\/fj.03-1401fje","article-title":"Regulation of endothelial glutathione by ICAM-1: implications for inflammation","volume":"18","author":"Kevil","year":"2004","journal-title":"FASEB J"},{"key":"10.1016\/j.ajog.2015.08.028_bib44","doi-asserted-by":"crossref","first-page":"2176","DOI":"10.1093\/bioinformatics\/btq401","article-title":"ROAST: rotation gene set tests for complex microarray experiments","volume":"26","author":"Wu","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.ajog.2015.08.028_bib45","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.1210\/en.2006-1289","article-title":"The effect of mechanical stretch on cyclooxygenase type 2 expression and activator protein-1 and nuclear factor-kappaB activity in human amnion cells","volume":"148","author":"Mohan","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.ajog.2015.08.028_bib46","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/S0002-9378(98)70271-6","article-title":"A\u00a0fetal systemic inflammatory response is followed by the spontaneous onset of preterm parturition","volume":"179","author":"Romero","year":"1998","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2015.08.028_bib47","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1530\/REP-07-0461","article-title":"Pro-labor myometrial gene expression: are preterm labor and term labor the same?","volume":"135","author":"Tattersall","year":"2008","journal-title":"Reproduction"},{"key":"10.1016\/j.ajog.2015.08.028_bib48","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1095\/biolreprod.104.032979","article-title":"Human myometrial gene expression before and\u00a0during parturition","volume":"72","author":"Havelock","year":"2005","journal-title":"Biol Reprod"},{"key":"10.1016\/j.ajog.2015.08.028_bib49","doi-asserted-by":"crossref","first-page":"3534","DOI":"10.1038\/sj.emboj.7601213","article-title":"Hepatocyte growth factor induces cell scattering through MAPK\/Egr-1-mediated upregulation of Snail","volume":"25","author":"Grotegut","year":"2006","journal-title":"EMBO J"},{"key":"10.1016\/j.ajog.2015.08.028_bib50","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1042\/bst0311171","article-title":"VEGF signaling: integration and multi-tasking in endothelial cell biology","volume":"31","author":"Zachary","year":"2003","journal-title":"Biochem Soc Trans"},{"key":"10.1016\/j.ajog.2015.08.028_bib51","doi-asserted-by":"crossref","first-page":"3361","DOI":"10.1007\/s11033-011-1106-6","article-title":"High mobility group box-1 induces migration of vascular smooth muscle cells via TLR4-dependent PI3K\/Akt pathway activation","volume":"39","author":"Yang","year":"2012","journal-title":"Mol Biol Rep"},{"key":"10.1016\/j.ajog.2015.08.028_bib52","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/S0962-8924(01)02179-1","article-title":"Cutting to the chase: calpain proteases in cell motility","volume":"12","author":"Glading","year":"2002","journal-title":"Trends Cell Biol"},{"key":"10.1016\/j.ajog.2015.08.028_bib53","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/ajhb.20840","article-title":"Early rapid growth, early birth: accelerated fetal growth and spontaneous late preterm birth","volume":"21","author":"Lampl","year":"2009","journal-title":"Am J Hum Biol"},{"key":"10.1016\/j.ajog.2015.08.028_bib54","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1016\/j.jbiomech.2012.04.001","article-title":"Dynamic material properties of the pregnant human uterus","volume":"45","author":"Manoogian","year":"2012","journal-title":"J\u00a0Biomech"},{"key":"10.1016\/j.ajog.2015.08.028_bib55","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1093\/humrep\/14.1.229","article-title":"Leukocytes infiltrate the myometrium during human parturition: further evidence that labor is an inflammatory process","volume":"14","author":"Thomson","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ajog.2015.08.028_bib56","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/molehr\/gag001","article-title":"Leukocyte density and pro-inflammatory cytokine expression in human fetal membranes, decidua, cervix and myometrium before and during labor at term","volume":"9","author":"Osman","year":"2003","journal-title":"Mol Hum Reprod"},{"issue":"Suppl","key":"10.1016\/j.ajog.2015.08.028_bib57","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1016\/j.ejogrb.2009.02.044","article-title":"Integration of endocrine and mechanical signals in the regulation of myometrial functions during pregnancy and labor","volume":"144","author":"Shynlova","year":"2009","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ajog.2015.08.028_bib58","doi-asserted-by":"crossref","first-page":"e79753","DOI":"10.1371\/journal.pone.0079753","article-title":"Periostin links mechanical strain to inflammation in abdominal aortic aneurysm","volume":"8","author":"Yamashita","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.ajog.2015.08.028_bib59","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1024\/0301-1526\/a000080","article-title":"PI-3K\/AKT signal pathway modulates vascular smooth muscle cells migration under cyclic mechanical strain","volume":"40","author":"Zhang","year":"2011","journal-title":"Vasa"},{"key":"10.1016\/j.ajog.2015.08.028_bib60","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1002\/jcb.22465","article-title":"Cyclic strain modulates migration and proliferation of vascular smooth muscle cells via Rho-GDIalpha, Rac1, and p38 pathway","volume":"109","author":"Qi","year":"2010","journal-title":"J\u00a0Cell Biochem"},{"key":"10.1016\/j.ajog.2015.08.028_bib61","doi-asserted-by":"crossref","first-page":"545018","DOI":"10.1155\/2015\/545018","article-title":"Effect of fluid shear stress on portal vein remodeling in a rat model of portal hypertension","volume":"2015","author":"Wen","year":"2015","journal-title":"Gastroenterol Res Pract"},{"key":"10.1016\/j.ajog.2015.08.028_bib62","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1089\/dna.2014.2480","article-title":"Shear stress in atherosclerotic plaque determination","volume":"33","author":"Li","year":"2014","journal-title":"DNA Cell Biol"},{"key":"10.1016\/j.ajog.2015.08.028_bib63","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1093\/cvr\/cvt090","article-title":"The effects of stenting on shear stress: relevance to endothelial injury and repair","volume":"99","author":"Van der Heiden","year":"2013","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.ajog.2015.08.028_bib64","doi-asserted-by":"crossref","first-page":"e106242","DOI":"10.1371\/journal.pone.0106242","article-title":"Mechanical stress is a pro-inflammatory stimulus in the gut: in\u00a0vitro, in\u00a0vivo and ex\u00a0vivo evidence","volume":"9","author":"Lin","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ajog.2015.08.028_bib65","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1111\/aji.12359","article-title":"Cyclic stretch augments production of neutrophil chemokines, matrix metalloproteinases, and activin a in human endometrial stromal cells","volume":"73","author":"Izumi","year":"2015","journal-title":"Am J Reprod Immunol"},{"key":"10.1016\/j.ajog.2015.08.028_bib66","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1136\/thoraxjnl-2013-204190","article-title":"Pulmonary venous hypertension and mechanical strain stimulate monocyte chemoattractant protein-1 release and structural remodeling of the lung in human and rodent chronic heart failure models","volume":"69","author":"Park","year":"2014","journal-title":"Thorax"},{"key":"10.1016\/j.ajog.2015.08.028_bib67","first-page":"122","article-title":"Changes in extracellular matrix materials in the uterine myometrium of rats during pregnancy and postparturition","volume":"41","author":"Nishinaka","year":"1991","journal-title":"Acta Pathol Jpn"},{"key":"10.1016\/j.ajog.2015.08.028_bib68","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1210\/endo.141.1.7264","article-title":"Focal adhesion signaling in the rat myometrium is abruptly terminated with the onset of labor","volume":"141","author":"Macphee","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.ajog.2015.08.028_bib69","doi-asserted-by":"crossref","first-page":"C1247","DOI":"10.1152\/ajpcell.1998.275.5.C1247","article-title":"Stretch activates heparin-binding EGF-like growth factor expression in bladder smooth muscle cells","volume":"275","author":"Park","year":"1998","journal-title":"Am J Physiol"},{"key":"10.1016\/j.ajog.2015.08.028_bib70","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1515\/jpm.2010.097","article-title":"Characterization of the myometrial transcriptome and biological pathways of spontaneous human labor at term","volume":"38","author":"Mittal","year":"2010","journal-title":"J\u00a0Perinat Med"},{"key":"10.1016\/j.ajog.2015.08.028_bib71","doi-asserted-by":"crossref","first-page":"3784","DOI":"10.1038\/onc.2013.363","article-title":"Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in\u00a0vivo","volume":"33","author":"Zhou","year":"2014","journal-title":"Oncogene"},{"key":"10.1016\/j.ajog.2015.08.028_bib72","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1038\/labinvest.3700282","article-title":"Local overexpression of HB-EGF exacerbates remodeling following myocardial infarction by activating noncardiomyocytes","volume":"85","author":"Ushikoshi","year":"2005","journal-title":"Lab Invest"},{"key":"10.1016\/j.ajog.2015.08.028_bib73","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.3892\/or.2013.2659","article-title":"Heparin-binding EGF-like growth factor enhances the activity of invasion and metastasis in thyroid cancer cells","volume":"30","author":"Ota","year":"2013","journal-title":"Oncol Rep"},{"key":"10.1016\/j.ajog.2015.08.028_bib74","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1016\/j.ajpath.2011.12.035","article-title":"Transforming growth factor beta-induced (TGFBI) is an anti-adhesive protein regulating the invasive growth of melanoma cells","volume":"180","author":"Nummela","year":"2012","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ajog.2015.08.028_bib75","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1159\/000061025","article-title":"Role of mechanical signals in the onset of term and preterm labor","volume":"27","author":"Lye","year":"2001","journal-title":"Front Horm Res"},{"key":"10.1016\/j.ajog.2015.08.028_bib76","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1067\/mob.2002.127720","article-title":"Failure of physiologic transformation of the spiral arteries in the placental bed in preterm premature rupture of membranes","volume":"187","author":"Kim","year":"2002","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2015.08.028_bib77","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1067\/S0002-9378(03)00838-X","article-title":"Failure of physiologic transformation of the spiral arteries in patients with preterm labor and intact membranes","volume":"189","author":"Kim","year":"2003","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2015.08.028_bib78","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.ajog.2010.08.009","article-title":"The \u201cgreat obstetrical ayndromes\u201d are associated with disorders of deep placentation","volume":"204","author":"Brosens","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2015.08.028_bib79","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1093\/molehr\/gah112","article-title":"Mechanical stretch of human uterine smooth muscle cells increases IL-8 mRNA expression and peptide synthesis","volume":"10","author":"Loudon","year":"2004","journal-title":"Mol Hum Reprod"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937815008947?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937815008947?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:33:08Z","timestamp":1762079588000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937815008947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":79,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["S0002937815008947"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2015.08.028","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Uterine overdistention induces preterm labor mediated by inflammation: observations in pregnant women and nonhuman primates","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2015.08.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}