{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T06:11:58Z","timestamp":1782886318669,"version":"3.54.5"},"reference-count":16,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100007921","name":"University of Pittsburgh","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007921","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["2 P50 DA005605-19 A2"],"award-info":[{"award-number":["2 P50 DA005605-19 A2"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HD 071859"],"award-info":[{"award-number":["HD 071859"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["HD047905"],"award-info":[{"award-number":["HD047905"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.ajog.2016.09.095","type":"journal-article","created":{"date-parts":[[2016,9,29]],"date-time":"2016-09-29T03:25:38Z","timestamp":1475119538000},"page":"64.e1-64.e7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":60,"title":["Dose-adjusted plasma concentrations of sublingual buprenorphine are lower during than after pregnancy"],"prefix":"10.1016","volume":"216","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6045-3162","authenticated-orcid":false,"given":"Jaime R.","family":"Bastian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huijun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongfei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Rothenberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7637-7942","authenticated-orcid":false,"given":"Ralph","family":"Tarter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"English","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raman","family":"Venkataramanan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve N.","family":"Caritis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2016.09.095_bib1","unstructured":"Center for Behavioral Health Statistics and Quality. Behavioral health trends in the United States: results from the 2014 National Survey on Drug Use and Health (HHS publication number SMA 15\u20134927, NSDUH Series H-50). 2015. Available at: http:\/\/www.samhsa.gov\/data\/."},{"key":"10.1016\/j.ajog.2016.09.095_bib2","series-title":"Medication-assisted treatment for opioid addiction during pregnancy. In: SAHMSA\/CSAT treatment improvement protocols","year":"2008"},{"key":"10.1016\/j.ajog.2016.09.095_bib3","first-page":"CD006318","article-title":"Maintenance agonist treatment for opiate dependent pregnant women (review)","author":"Minozzi","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ajog.2016.09.095_bib4","doi-asserted-by":"crossref","first-page":"2320","DOI":"10.1056\/NEJMoa1005359","article-title":"Neonatal abstinence syndrome after methadone or buprenorphine exposure","volume":"363","author":"Jones","year":"2010","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ajog.2016.09.095_bib5","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1080\/08897077.2015.1012613","article-title":"Practice guidance for buprenorphine for the treatment of opioid use disorders: results of an expert panel process","volume":"36","author":"Farmer","year":"2015","journal-title":"Subst Abuse"},{"key":"10.1016\/j.ajog.2016.09.095_bib6","series-title":"Buprenorphine sublingual tablets","author":"Reckitt","year":"2015"},{"key":"10.1016\/j.ajog.2016.09.095_bib7","series-title":"Clinical Pharmacology During Pregnancy","year":"2013"},{"key":"10.1016\/j.ajog.2016.09.095_bib8","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1097\/FTD.0b013e318228bb2a","article-title":"Preliminary buprenorphine sublingual tablet pharmacokinetic data in plasma, oral fluid and sweat during treatment of opioid-dependent pregnant women","volume":"33","author":"Concheiro","year":"2011","journal-title":"Ther Drug Monit"},{"key":"10.1016\/j.ajog.2016.09.095_bib9","doi-asserted-by":"crossref","first-page":"661","DOI":"10.2165\/00003088-200544070-00001","article-title":"Buprenorphine\u2014clinical\u00a0pharmacokinetics in the treatment of opioid dependence","volume":"44","author":"Elkader","year":"2005","journal-title":"Clin Pharmacokinet"},{"key":"10.1016\/j.ajog.2016.09.095_bib10","doi-asserted-by":"crossref","first-page":"989","DOI":"10.2165\/00003088-200544100-00001","article-title":"Pregnancy-induced changes in pharmacokinetics: a mechanistic based approach","volume":"44","author":"Anderson","year":"2005","journal-title":"Clin Pharmacokinet"},{"key":"10.1016\/j.ajog.2016.09.095_bib11","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1053\/j.semperi.2015.08.003","article-title":"Pharmacokinetics of drugs in pregnancy","volume":"39","author":"Feghali","year":"2015","journal-title":"Semin Perinatol"},{"key":"10.1016\/j.ajog.2016.09.095_bib12","doi-asserted-by":"crossref","first-page":"53","DOI":"10.11622\/smedj.2015010","article-title":"Prevalence of oral lesions and measurement of salivary pH in the different trimesters of pregnancy","volume":"56","author":"Jain","year":"2015","journal-title":"Singapore Med J"},{"key":"10.1016\/j.ajog.2016.09.095_bib13","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1159\/000279766","article-title":"Bioavailability of buprenorphine from crushed and whole buprenorphine (Subutex) tablets","volume":"16","author":"Simojoki","year":"2010","journal-title":"Eur Addict Res"},{"key":"10.1016\/j.ajog.2016.09.095_bib14","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/0002-9378(89)90225-1","article-title":"Pharmacokinetics of orally administered ritodrine","volume":"161","author":"Caritis","year":"1989","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2016.09.095_bib15","series-title":"Federal guidelines for opioid treatment programs. Health and Human Services publication no. (SMA) PEP15-FEDGUIDEOTP","year":"2015"},{"key":"10.1016\/j.ajog.2016.09.095_bib16","series-title":"Guidelines for the psychosocially assisted pharmacological treatment for opioid dependence","year":"2009"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000293781630816X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000293781630816X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T11:10:59Z","timestamp":1757589059000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000293781630816X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["S000293781630816X"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2016.09.095","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dose-adjusted plasma concentrations of sublingual buprenorphine are lower during than after pregnancy","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2016.09.095","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}