{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:01:02Z","timestamp":1790420462226,"version":"4.1.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1016\/j.ajog.2017.01.002","type":"journal-article","created":{"date-parts":[[2017,1,16]],"date-time":"2017-01-16T15:07:59Z","timestamp":1484579279000},"page":"518.e1-518.e12","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":84,"title":["Leading causes of preterm delivery as risk factors for intraventricular hemorrhage in very preterm infants: results of the EPIPAGE 2 cohort study"],"prefix":"10.1016","volume":"216","author":[{"given":"Marie","family":"Chevallier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Debillon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronique","family":"Pierrat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Delorme","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Kayem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e9lanie","family":"Durox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Goffinet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephane","family":"Marret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre Yves","family":"Ancel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Arnaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Baud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Bednarek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Claris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyril","family":"Flamant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Gire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elie","family":"Saliba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Brissaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie Laure","family":"Charkaluk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geraldine","family":"Favrais","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Bodeau-Livinec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2017.01.002_bib1","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1001\/jamapediatrics.2014.3351","article-title":"Survival and morbidity of preterm children born at 22 through 34 weeks\u2019 gestation in France in 2011: results of the EPIPAGE-2 cohort study","volume":"169","author":"Ancel","year":"2015","journal-title":"JAMA Pediatr"},{"key":"10.1016\/j.ajog.2017.01.002_bib2","doi-asserted-by":"crossref","first-page":"e7976","DOI":"10.1136\/bmj.e7976","article-title":"Short term outcomes after extreme preterm birth in England: comparison of two birth cohorts in 1995 and 2006 (the EPICure studies)","volume":"345","author":"Costeloe","year":"2012","journal-title":"BMJ"},{"key":"10.1016\/j.ajog.2017.01.002_bib3","doi-asserted-by":"crossref","first-page":"F188","DOI":"10.1136\/adc.2008.156745","article-title":"Changes in care and outcome of very preterm babies in the Parisian region between 1998 and 2003","volume":"95","author":"Zeitlin","year":"2009","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.ajog.2017.01.002_bib4","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/mrdd.20107","article-title":"Perinatal white matter injury: the changing spectrum of pathology and emerging insights into pathogenetic mechanisms","volume":"12","author":"Back","year":"2006","journal-title":"Ment Retard Dev Disabil Res Rev"},{"key":"10.1016\/j.ajog.2017.01.002_bib5","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0140-6736(07)60030-0","article-title":"Trends in cerebral palsy among infants of very low birthweight (<1500 g) or born prematurely (<32 weeks) in 16 European centers: a database study","volume":"369","author":"Platt","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.ajog.2017.01.002_bib6","doi-asserted-by":"crossref","first-page":"e0114567","DOI":"10.1371\/journal.pone.0114567","article-title":"Comparison in outcomes at two years of age of very preterm infants born in 2000, 2005 and 2010","volume":"10","author":"Abily-Donval","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.ajog.2017.01.002_bib7","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/j.ajog.2005.11.046","article-title":"Plurality-dependent risk of severe intraventricular hemorrhage among very low birth weight infants and antepartum corticosteroid treatment","volume":"194","author":"Blickstein","year":"2006","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2017.01.002_bib8","doi-asserted-by":"crossref","first-page":"147.e1","DOI":"10.1016\/j.ajog.2006.09.014","article-title":"Trends in neonatal morbidity and mortality for very low birthweight infants","volume":"196","author":"Fanaroff","year":"2007","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2017.01.002_bib9","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1055\/s-0029-1214237","article-title":"Severe intraventricular hemorrhage in preterm infants: comparison of risk factors and short-term neonatal morbidities between grade 3 and grade 4 intraventricular hemorrhage","volume":"26","author":"Sarkar","year":"2009","journal-title":"Am J Perinatol"},{"key":"10.1016\/j.ajog.2017.01.002_bib10","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1177\/0883073809338064","article-title":"Intraventricular hemorrhage and cystic periventricular leukomalacia in preterm infants: how are they related?","volume":"24","author":"Kusters","year":"2009","journal-title":"J\u00a0Child Neurol"},{"key":"10.1016\/j.ajog.2017.01.002_bib11","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1542\/peds.2009-2959","article-title":"Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network","volume":"126","author":"Stoll","year":"2010","journal-title":"Pediatrics"},{"key":"10.1016\/j.ajog.2017.01.002_bib12","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1053\/siny.1999.0112","article-title":"Mechanisms of perinatal brain injury","volume":"5","author":"Inder","year":"2000","journal-title":"Semin Neonatol"},{"key":"10.1016\/j.ajog.2017.01.002_bib13","series-title":"Neurology of the Newborn","first-page":"481","article-title":"Intracranial hemorrhage: germinal matrix hemorrhage of the premature infant","author":"Volpe","year":"2008"},{"key":"10.1016\/j.ajog.2017.01.002_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1203\/PDR.0b013e3181c1b176","article-title":"Intraventricular hemorrhage in premature infants: mechanism of disease","volume":"67","author":"Ballabh","year":"2010","journal-title":"Pediatr Res"},{"key":"10.1016\/j.ajog.2017.01.002_bib15","doi-asserted-by":"crossref","first-page":"e590","DOI":"10.1542\/peds.111.5.e590","article-title":"Risk factors for intraventricular hemorrhage in very low birth weight premature infants: a retrospective case-control study","volume":"111","author":"Linder","year":"2003","journal-title":"Pediatrics"},{"key":"10.1016\/j.ajog.2017.01.002_bib16","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/AOG.0b013e31817cfdf1","article-title":"Delivery mode and severe intraventricular hemorrhage in single, very low birth weight, vertex infants","volume":"112","author":"Riskin","year":"2008","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2017.01.002_bib17","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1111\/j.1651-2227.2010.01846.x","article-title":"Incidence of and risk factors for neonatal morbidity after active perinatal care: extremely preterm infants study in Sweden (EXPRESS)","volume":"99","year":"2010","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.ajog.2017.01.002_bib18","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1053\/ejpn.2001.0494","article-title":"Unilateral parenchymal hemorrhagic infarction in the preterm infant","volume":"5","author":"de Vries","year":"2001","journal-title":"Eur J Paediatr Neurol"},{"key":"10.1016\/j.ajog.2017.01.002_bib19","doi-asserted-by":"crossref","first-page":"F86","DOI":"10.1136\/fn.86.2.F86","article-title":"Perinatal risk factors for major intraventricular hemorrhage in the Australian and New Zealand Neonatal Network, 1995-97","volume":"86","author":"Heuchan","year":"2002","journal-title":"Arch Dis Child-Fetal Neonatal Ed"},{"key":"10.1016\/j.ajog.2017.01.002_bib20","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/0002-9378(95)90001-2","article-title":"Antenatal steroids, delivery mode, and intraventricular hemorrhage in preterm infants","volume":"172","author":"Ment","year":"1995","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2017.01.002_bib21","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1471-0528.2010.02751.x","article-title":"Antenatal steroids and neonatal outcome after chorioamnionitis: a meta-analysis","volume":"118","author":"Been","year":"2011","journal-title":"BJOG"},{"key":"10.1016\/j.ajog.2017.01.002_bib22","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0140-6736(08)60074-4","article-title":"Epidemiology and causes of preterm birth","volume":"371","author":"Goldenberg","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.ajog.2017.01.002_bib23","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jgyn.2012.04.014","article-title":"Trends in perinatal health in France from 1995 to 2010. Results from the French National Perinatal Surveys","volume":"41","author":"Blondel","year":"2012","journal-title":"J\u00a0Gynecol Obstet Biol Reprod (Paris)"},{"key":"10.1016\/j.ajog.2017.01.002_bib24","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1212\/WNL.58.12.1726","article-title":"Practice parameter: neuroimaging of the neonate: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society","volume":"58","author":"Ment","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.ajog.2017.01.002_bib25","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0022-3476(78)80282-0","article-title":"Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm","volume":"92","author":"Papile","year":"1978","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.ajog.2017.01.002_bib26","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1136\/adc.56.12.900","article-title":"Measurement of the growth of the lateral ventricles in preterm infants with real-time ultrasound","volume":"56","author":"Levene","year":"1981","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.ajog.2017.01.002_bib27","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1097\/AOG.0000000000001179","article-title":"Cause of preterm birth as a prognostic factor for mortality","volume":"127","author":"Delorme","year":"2016","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2017.01.002_bib28","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0887-8994(97)00073-8","article-title":"Pregnancy-induced hypertension and reduced intraventricular hemorrhage in preterm infants","volume":"17","author":"Perlman","year":"1997","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.ajog.2017.01.002_bib29","doi-asserted-by":"crossref","first-page":"F223","DOI":"10.1136\/archdischild-2015-308396","article-title":"Variables associated with the decreased risk of intraventricular hemorrhage in a large sample of neonates with respiratory distress syndrome","volume":"101","author":"Doshi","year":"2016","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.ajog.2017.01.002_bib30","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1007\/s00381-012-1875-9","article-title":"Risk and protective factors of intraventricular hemorrhage in preterm babies in Wuhan, China","volume":"28","author":"Rong","year":"2012","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.ajog.2017.01.002_bib31","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.clp.2013.09.007","article-title":"Pathogenesis and prevention of intraventricular hemorrhage","volume":"41","author":"Ballabh","year":"2014","journal-title":"Clin Perinatol"},{"key":"10.1016\/j.ajog.2017.01.002_bib32","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jpeds.2010.11.003","article-title":"Interruption of placental blood flow during labor: potential systemic and cerebral organ consequences","volume":"158","author":"Perlman","year":"2011","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.ajog.2017.01.002_bib33","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1007\/s00381-016-3217-9","article-title":"Role of selected cytokines in the etiopathogenesis of intraventricular hemorrhage in preterm newborns","volume":"32","author":"Szpecht","year":"2016","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.ajog.2017.01.002_bib34","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.clp.2013.10.009","article-title":"Chorioamnionitis in the pathogenesis of brain injury in preterm infants","volume":"41","author":"Chau","year":"2014","journal-title":"Clin Perinatol"},{"key":"10.1016\/j.ajog.2017.01.002_bib35","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1177\/0883073812463068","article-title":"Systemic inflammation, intraventricular hemorrhage, and white matter injury","volume":"28","author":"Leviton","year":"2013","journal-title":"J\u00a0Child Neurol"},{"key":"10.1016\/j.ajog.2017.01.002_bib36","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.ajog.2004.11.057","article-title":"Are maternal hypertension and small-for-gestational age risk factors for severe intraventricular hemorrhage and cystic periventricular leukomalacia? Results of the EPIPAGE cohort study","volume":"193","author":"Ancel","year":"2005","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2017.01.002_bib37","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/1471-2393-11-26","article-title":"Maternal markers for detecting early-onset neonatal infection and chorioamnionitis in cases of premature rupture of membranes at or after 34 weeks of gestation: a two-center prospective study","volume":"11","author":"Popowski","year":"2011","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.ajog.2017.01.002_bib38","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.gyobfe.2010.11.006","article-title":"Prediction of maternofetal infection in preterm premature rupture of membranes: serum maternal markers","volume":"39","author":"Popowski","year":"2011","journal-title":"Gynecol Obstet Fertil"},{"key":"10.1016\/j.ajog.2017.01.002_bib39","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1111\/j.1471-0528.1987.tb02316.x","article-title":"Is C-reactive protein really useful in preterm premature rupture of the membranes?","volume":"94","author":"Fisk","year":"1987","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.ajog.2017.01.002_bib40","doi-asserted-by":"crossref","first-page":"e107880","DOI":"10.1371\/journal.pone.0107880","article-title":"Assessment of predictive markers for placental inflammatory response in preterm births","volume":"9","author":"Kim","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ajog.2017.01.002_bib41","first-page":"1080","article-title":"Amniotic fluid infection, cytokines, and adverse outcome among infants at 34 weeks\u2019 gestation or less","volume":"98","author":"Hitti","year":"2001","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2017.01.002_bib42","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0002-9378(97)70432-0","article-title":"Amniotic fluid inflammatory cytokines (interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha), neonatal brain white matter lesions, and cerebral palsy","volume":"177","author":"Yoon","year":"1997","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2017.01.002_bib43","doi-asserted-by":"crossref","first-page":"308.e1","DOI":"10.1016\/j.ajog.2014.05.030","article-title":"Neonatal and early childhood outcomes following early vs later preterm premature rupture of membranes","volume":"211","author":"Manuck","year":"2014","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2017.01.002_bib44","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0002-9378(97)70485-X","article-title":"Obstetric antecedents of intraventricular hemorrhage and periventricular leukomalacia in the low-birth-weight neonate","volume":"176","author":"Verma","year":"1997","journal-title":"Am J Obstet Gynecol"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937817301023?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937817301023?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T11:14:32Z","timestamp":1757589272000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937817301023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":44,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["S0002937817301023"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2017.01.002","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Leading causes of preterm delivery as risk factors for intraventricular hemorrhage in very preterm infants: results of the EPIPAGE 2 cohort study","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2017.01.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}