{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T06:21:29Z","timestamp":1790144489561,"version":"4.0.1"},"reference-count":23,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.ajog.2018.08.034","type":"journal-article","created":{"date-parts":[[2018,8,25]],"date-time":"2018-08-25T11:09:33Z","timestamp":1535195373000},"page":"390.e1-390.e15","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":180,"title":["Maternal age and risk for adverse outcomes"],"prefix":"10.1016","volume":"219","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5627-2262","authenticated-orcid":false,"given":"Jean-Ju","family":"Sheen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason D.","family":"Wright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dena","family":"Goffman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7932-1987","authenticated-orcid":false,"given":"Adina R.","family":"Kern-Goldberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Whitney","family":"Booker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zainab","family":"Siddiq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1457-6284","authenticated-orcid":false,"given":"Mary E.","family":"D\u2019Alton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5246-0824","authenticated-orcid":false,"given":"Alexander M.","family":"Friedman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2018.08.034_bib1","first-page":"1","article-title":"Births in the United States, 2016","author":"Martin","year":"2017","journal-title":"NCHS Data Brief"},{"key":"10.1016\/j.ajog.2018.08.034_bib2","series-title":"Births: provisional data for 2016. Vital statistics rapid release, no 2","author":"Hamilton","year":"2017"},{"key":"10.1016\/j.ajog.2018.08.034_bib3","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1016\/j.fertnstert.2013.07.201","article-title":"What do reproductive-age women who undergo oocyte cryopreservation think about the process as a means to preserve fertility?","volume":"100","author":"Hodes-Wertz","year":"2013","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ajog.2018.08.034_bib4","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1016\/j.fertnstert.2015.03.004","article-title":"Reproduction at an advanced maternal age and maternal health","volume":"103","author":"Sauer","year":"2015","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ajog.2018.08.034_bib5","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1001\/jama.1992.03490100073030","article-title":"Reversing the natural decline in human fertility. An extended clinical trial of oocyte donation to women of advanced reproductive age","volume":"268","author":"Sauer","year":"1992","journal-title":"JAMA"},{"key":"10.1016\/j.ajog.2018.08.034_bib6","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/0140-6736(93)90132-Z","article-title":"Pregnancy after age 50: application of oocyte donation to women after natural menopause","volume":"341","author":"Sauer","year":"1993","journal-title":"Lancet"},{"key":"10.1016\/j.ajog.2018.08.034_bib7","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1055\/s-0028-1085620","article-title":"Advanced maternal age. Part I: obstetric complications","volume":"25","author":"Usta","year":"2008","journal-title":"Am J Perinatol"},{"key":"10.1016\/j.ajog.2018.08.034_bib8","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.fertnstert.2014.09.037","article-title":"Pregnancy outcomes in very advanced maternal age pregnancies: the impact of assisted reproductive technology","volume":"103","author":"Jackson","year":"2015","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ajog.2018.08.034_bib9","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1007\/s10995-015-1914-8","article-title":"Pregnancy and birth outcomes among primiparae at very advanced maternal age: at what price?","volume":"20","author":"Ben-David","year":"2016","journal-title":"Matern Child Health J"},{"key":"10.1016\/j.ajog.2018.08.034_bib10","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1002\/uog.12494","article-title":"Maternal age and adverse pregnancy outcome: a cohort study","volume":"42","author":"Khalil","year":"2013","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajog.2018.08.034_bib11","doi-asserted-by":"crossref","first-page":"2479","DOI":"10.1001\/jama.2010.841","article-title":"Adherence to surgical care improvement project measures and the asssociation with postoperative infections","volume":"303","author":"Stulberg","year":"2010","journal-title":"JAMA"},{"key":"10.1016\/j.ajog.2018.08.034_bib12","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1213\/ANE.0000000000002041","article-title":"Trends in perioperative practice and resource utilization in patients with obstructive sleep apnea undergoing joint arthroplasty","volume":"125","author":"Cozowicz","year":"2017","journal-title":"Anesth Analg"},{"key":"10.1016\/j.ajog.2018.08.034_bib13","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1055\/s-0036-1571284","article-title":"Change in off-label use of bone morphogenetic protein in spine surgery and associations with adverse outcome","volume":"6","author":"Poeran","year":"2016","journal-title":"Global Spine J"},{"key":"10.1016\/j.ajog.2018.08.034_bib14","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1097\/AAP.0000000000000342","article-title":"Trends in the use of regional anesthesia: neuraxial and peripheral nerve blocks","volume":"41","author":"Cozowicz","year":"2016","journal-title":"Reg Anesth Pain Med"},{"key":"10.1016\/j.ajog.2018.08.034_bib15","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/s10995-007-0256-6","article-title":"An enhanced method for identifying obstetric deliveries: implications for estimating maternal morbidity","volume":"12","author":"Kuklina","year":"2008","journal-title":"Matern Child Health J"},{"key":"10.1016\/j.ajog.2018.08.034_bib16","unstructured":"Centers for Disease Control and Prevention. Severe maternal morbidity in the United\u00a0States.\u00a0Available at: https:\/\/www.cdc.gov\/reproductivehealth\/maternalinfanthealth\/severematernalmorbidity.html. Accessed Jan. 20,\u00a02018."},{"key":"10.1016\/j.ajog.2018.08.034_bib17","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/S0002-9378(11)90678-4","article-title":"Risk factors for third-degree and fourth-degree perineal lacerations in forceps and vacuum deliveries","volume":"163","author":"Combs","year":"1990","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2018.08.034_bib18","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1097\/AOG.0b013e3182a603bb","article-title":"Development of a comorbidity index for use in obstetric patients","volume":"122","author":"Bateman","year":"2013","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2018.08.034_bib19","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1111\/1471-0528.13254","article-title":"Validation of an obstetric comorbidity index in an external population","volume":"122","author":"Metcalfe","year":"2015","journal-title":"BJOG"},{"key":"10.1016\/j.ajog.2018.08.034_bib20","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.midw.2012.04.001","article-title":"Maternal age >\/=45 years and maternal and perinatal outcomes: a review of the evidence","volume":"29","author":"Carolan","year":"2013","journal-title":"Midwifery"},{"key":"10.1016\/j.ajog.2018.08.034_bib21","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1111\/1471-0528.14269","article-title":"Pregnancy at very advanced maternal age: a UK population-based cohort study","volume":"124","author":"Fitzpatrick","year":"2017","journal-title":"BJOG"},{"key":"10.1016\/j.ajog.2018.08.034_bib22","doi-asserted-by":"crossref","first-page":"558.e1","DOI":"10.1016\/j.ajog.2010.07.039","article-title":"Pregnancy outcome at extremely advanced maternal age","volume":"203","author":"Yogev","year":"2010","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2018.08.034_bib23","first-page":"935","article-title":"Effect of very advanced maternal age on pregnancy outcome and rate of cesarean delivery","volume":"92","author":"Dulitzki","year":"1998","journal-title":"Obstet Gynecol"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937818307130?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937818307130?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T11:21:58Z","timestamp":1757589718000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937818307130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["S0002937818307130"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2018.08.034","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Maternal age and risk for adverse outcomes","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2018.08.034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}