{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:05:28Z","timestamp":1792811128869,"version":"4.5.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1016\/j.ajog.2019.11.1252","type":"journal-article","created":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T02:41:20Z","timestamp":1574217680000},"page":"493.e1-493.e13","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Cervicovaginal fluid proteomic analysis to identify potential biomarkers for preterm birth"],"prefix":"10.1016","volume":"222","author":[{"given":"Samuel","family":"Parry","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Leite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Sean","family":"Esplin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radek","family":"Bukowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Varner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William W.","family":"Andrews","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George R.","family":"Saade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Ilekis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uma M.","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoel","family":"Sadovsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian A.","family":"Blair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Biggio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2019.11.1252_bib1","first-page":"139","article-title":"Annual summary of vital statistics: 2013\u20132014","author":"Murphy","year":"2017","journal-title":"Pediatrics"},{"key":"10.1016\/j.ajog.2019.11.1252_bib2","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0140-6736(08)60074-4","article-title":"Epidemiology and causes of preterm birth","volume":"371","author":"Goldenberg","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.ajog.2019.11.1252_bib3","doi-asserted-by":"crossref","first-page":"678.e1","DOI":"10.1016\/j.ajog.2014.06.035","article-title":"Maternal serum serpin B7 is associated with early spontaneous preterm birth","volume":"211","author":"Parry","year":"2014","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2019.11.1252_bib4","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1021\/pr0605419","article-title":"Comprehensive proteomic analysis of human cervical-vaginal fluid","volume":"6","author":"Dasari","year":"2007","journal-title":"J\u00a0Proteome Res"},{"key":"10.1016\/j.ajog.2019.11.1252_bib5","doi-asserted-by":"crossref","first-page":"391.e1","DOI":"10.1016\/j.ajog.2010.09.021","article-title":"Proteomic identification of serum peptides predicting subsequent spontaneous preterm birth","volume":"204","author":"Esplin","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2019.11.1252_bib6","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.3109\/14767058.2013.852172","article-title":"Proteomic analysis of cervical vaginal fluid proteins among women in recurrent preterm labor","volume":"27","author":"Lo","year":"2014","journal-title":"J\u00a0Matern Fetal Neonatal Med"},{"key":"10.1016\/j.ajog.2019.11.1252_bib7","doi-asserted-by":"crossref","first-page":"633.e1","DOI":"10.1016\/j.ajog.2016.02.001","article-title":"Development and validation of a spontaneous preterm delivery predictor in asymptomatic women","volume":"214","author":"Saade","year":"2016","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2019.11.1252_bib8","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1021\/pr8010342","article-title":"Identification and quantification of preterm birth biomarkers in human cervicovaginal fluid by liquid chromatography\/tandem mass spectrometry","volume":"8","author":"Shah","year":"2009","journal-title":"J\u00a0Proteome Res"},{"key":"10.1016\/j.ajog.2019.11.1252_bib9","doi-asserted-by":"crossref","first-page":"3161","DOI":"10.1021\/pr060282n","article-title":"An initial proteomic analysis of human preterm labor: placental membranes","volume":"5","author":"Butt","year":"2006","journal-title":"J\u00a0Proteome Res"},{"key":"10.1016\/j.ajog.2019.11.1252_bib10","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1021\/pr0605421","article-title":"Identification of novel protein biomarkers of preterm birth in human cervical-vaginal fluid","volume":"6","author":"Pereira","year":"2007","journal-title":"J\u00a0Proteome Res"},{"key":"10.1016\/j.ajog.2019.11.1252_bib11","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1093\/bfgp\/eln032","article-title":"Proteomics: from hypothesis to quantitative assay on a single platform. Guidelines for developing MRM assays using ion trap mass spectrometers","volume":"7","author":"Han","year":"2008","journal-title":"Brief Funct Genomic Proteomic"},{"key":"10.1016\/j.ajog.2019.11.1252_bib12","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1074\/mcp.M700354-MCP200","article-title":"Quantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry and stable isotope dilution","volume":"6","author":"Keshishian","year":"2007","journal-title":"Mol Cell Proteomics"},{"key":"10.1016\/j.ajog.2019.11.1252_bib13","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1530\/REP-13-0175","article-title":"Prediction of spontaneous preterm labour in at-risk pregnant women","volume":"146","author":"Liong","year":"2013","journal-title":"Reproduction"},{"key":"10.1016\/j.ajog.2019.11.1252_bib14","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1111\/1471-0528.12993","article-title":"New biomarkers for the prediction of spontaneous preterm labour in symptomatic pregnant women: a comparison with fetal fibronectin","volume":"122","author":"Liong","year":"2015","journal-title":"BJOG"},{"key":"10.1016\/j.ajog.2019.11.1252_bib15","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1530\/REP-12-0264","article-title":"Proteomic analysis of human cervicovaginal fluid collected before preterm premature rupture of the fetal membranes","volume":"145","author":"Liong","year":"2013","journal-title":"Reproduction"},{"issue":"Pt 3","key":"10.1016\/j.ajog.2019.11.1252_bib16","first-page":"483","article-title":"Confocal and conventional immunofluorescence and ultrastructural localisation of intracellular strength-giving components of human amniochorion","volume":"183","author":"Ockleford","year":"1993","journal-title":"J\u00a0Anat"},{"key":"10.1016\/j.ajog.2019.11.1252_bib17","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1586\/epr.13.7","article-title":"Sensitivity and specificity: twin goals of proteomics assays. Can they be combined?","volume":"10","author":"Wilson","year":"2013","journal-title":"Expert Rev Proteomics"},{"key":"10.1016\/j.ajog.2019.11.1252_bib18","doi-asserted-by":"crossref","first-page":"R182","DOI":"10.1093\/hmg\/ddw214","article-title":"Mission critical: the need for proteomics in the era of next-generation sequencing and precision medicine","volume":"25","author":"Cayer","year":"2016","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.ajog.2019.11.1252_bib19","doi-asserted-by":"crossref","first-page":"385","DOI":"10.2147\/IJWH.S79577","article-title":"Utility of proteomics in obstetric disorders: a review","volume":"7","author":"Hernandez-Nunez","year":"2015","journal-title":"Int J Womens Health"},{"key":"10.1016\/j.ajog.2019.11.1252_bib20","doi-asserted-by":"crossref","first-page":"517.e1","DOI":"10.1016\/j.ajog.2015.11.001","article-title":"The relationship of circulating proteins in early pregnancy with preterm birth","volume":"214","author":"Lynch","year":"2016","journal-title":"Am J Obstet Gynecol"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937819326316?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937819326316?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T11:27:33Z","timestamp":1757590053000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937819326316"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["S0002937819326316"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2019.11.1252","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.736974051.793574646","asserted-by":"object"}]},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cervicovaginal fluid proteomic analysis to identify potential biomarkers for preterm birth","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2019.11.1252","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}