{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T20:15:49Z","timestamp":1788466549444,"version":"build-2803163510"},"reference-count":21,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001505","name":"Health Research Council of New Zealand","doi-asserted-by":"publisher","award":["HRC 13\/143"],"award-info":[{"award-number":["HRC 13\/143"]}],"id":[{"id":"10.13039\/501100001505","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001513","name":"Cancer Society of New Zealand","doi-asserted-by":"publisher","award":["CS 12\/30"],"award-info":[{"award-number":["CS 12\/30"]}],"id":[{"id":"10.13039\/501100001513","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.ajog.2020.02.029","type":"journal-article","created":{"date-parts":[[2020,2,25]],"date-time":"2020-02-25T12:09:05Z","timestamp":1582632545000},"page":"408.e1-408.e11","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Evaluation of guidelines for observational management of cervical intraepithelial neoplasia 2 in young women"],"prefix":"10.1016","volume":"223","author":[{"given":"Kieran","family":"Dempster-Rivett","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4230-7791","authenticated-orcid":false,"given":"Carrie R.","family":"Innes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryony J.","family":"Simcock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianne","family":"Harker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan A.","family":"Williman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachael A.","family":"Van Der Griend","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Whitehead","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merilyn","family":"Hibma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beverley A.","family":"Lawton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Fitzgerald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narena M.","family":"Dudley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Petrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jim","family":"Faherty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecile","family":"Bergzoll","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lois","family":"Eva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"Sadler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selvan","family":"Pather","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. David","family":"Wrede","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter H.","family":"Sykes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2020.02.029_bib1","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.ajog.2011.06.069","article-title":"Is the treatment of CIN 2 always necessary in women under 25 years old?","volume":"205","author":"Mcallum","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2020.02.029_bib2","doi-asserted-by":"crossref","first-page":"k499","DOI":"10.1136\/bmj.k499","article-title":"Clinical course of untreated cervical intraepithelial neoplasia grade 2 under active surveillance: systematic review and meta-analysis","volume":"360","author":"Tainio","year":"2018","journal-title":"BMJ"},{"key":"10.1016\/j.ajog.2020.02.029_bib3","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1097\/AOG.0b013e3182883a34","article-title":"2012 Updated consensus guidelines for the management of abnormal cervical cancer screening tests and cancer precursors","volume":"121","author":"Massad","year":"2013","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2020.02.029_bib4","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1080\/01443615.2017.1316973","article-title":"Conservative management of CIN2: National audit of British Society for Colposcopy and Cervical Pathology members' opinion","volume":"38","author":"Macdonald","year":"2018","journal-title":"J\u00a0Obstet Gynaecol"},{"key":"10.1016\/j.ajog.2020.02.029_bib5","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1097\/LGT.0000000000000244","article-title":"Observational management of CIN 2 in young women: a prospective multicenter trial","volume":"20","author":"Sykes","year":"2016","journal-title":"J\u00a0Low Genit Tract Dis"},{"key":"10.1016\/j.ajog.2020.02.029_bib6","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/S1470-2045(08)70103-7","article-title":"Natural history of cervical neoplasia and risk of invasive cancer in women with cervical intraepithelial neoplasia 3: a retrospective cohort study","volume":"9","author":"McCredie","year":"2008","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ajog.2020.02.029_bib8","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1186\/1471-2458-10-734","article-title":"Cervical cancer screening in Australia: modelled evaluation of the impact of changing the recommended interval from two to three years","volume":"10","author":"Creighton","year":"2010","journal-title":"BMC Public Health"},{"key":"10.1016\/j.ajog.2020.02.029_bib9","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1097\/LGT.0b013e3181fb4547","article-title":"Regardless of skill, performing more biopsies increases the sensitivity of colposcopy","volume":"15","author":"Pretorius","year":"2011","journal-title":"J\u00a0Low Genit Tract Dis"},{"key":"10.1016\/j.ajog.2020.02.029_bib10","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.ajog.2004.02.065","article-title":"Colposcopically directed biopsy, random cervical biopsy, and endocervical curettage in the diagnosis of cervical intraepithelial neoplasia II or worse","volume":"191","author":"Pretorius","year":"2004","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2020.02.029_bib11","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1002\/ijc.25470","article-title":"The accuracy of colposcopic biopsy: analyses from the placebo arm of the Gardasil clinical trials","volume":"128","author":"Stoler","year":"2011","journal-title":"Int J Cancer"},{"key":"10.1016\/j.ajog.2020.02.029_bib12","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1001\/jama.285.11.1500","article-title":"Atypical Squamous Cells of Undetermined Significance\u2212Low-Grade Squamous Intraepithelial Lesion Triage Study G. Interobserver reproducibility of cervical cytologic and histologic interpretations: realistic estimates from the ASCUS-LSIL Triage Study","volume":"285","author":"Stoler","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.ajog.2020.02.029_bib13","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1097\/pgp.0b013e31805152ab","article-title":"CIN2 is a much less reproducible and less valid diagnosis than CIN3: results from a histological review of population-based cervical samples","volume":"26","author":"Carreon","year":"2007","journal-title":"Int J Gynecol Pathol"},{"key":"10.1016\/j.ajog.2020.02.029_bib14","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1097\/PAS.0000000000000381","article-title":"The interpretive variability of cervical biopsies and its relationship to HPV status","volume":"39","author":"Stoler","year":"2015","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.ajog.2020.02.029_bib15","first-page":"72","article-title":"Impact of human papillomavirus vaccination on rates of abnormal cervical cytology and histology in young New Zealand women","volume":"133","author":"Innes","year":"2020","journal-title":"N\u00a0Z Med J"},{"key":"10.1016\/j.ajog.2020.02.029_bib16","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.vaccine.2015.10.138","article-title":"Response to Pendleton et\u00a0al. regarding reduction in HPV 16\/18-associated high grade cervical lesions following HPV vaccine introduction in the United States","volume":"34","author":"Hariri","year":"2016","journal-title":"Vaccine"},{"key":"10.1016\/j.ajog.2020.02.029_bib17","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1016\/j.vaccine.2015.01.084","article-title":"Reduction in HPV 16\/18-associated high grade cervical lesions following HPV vaccine introduction in the United States\u25002008-2012","volume":"33","author":"Hariri","year":"2015","journal-title":"Vaccine"},{"key":"10.1016\/j.ajog.2020.02.029_bib18","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1097\/AOG.0000000000002193","article-title":"Change in human papillomavirus prevalence among U.S. women aged 18-59 years, 2009-2014","volume":"130","author":"Berenson","year":"2017","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2020.02.029_bib20","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1080\/07853890.2018.1426875","article-title":"On surmounting the barriers to HPV vaccination: we can do better","volume":"50","author":"Attia","year":"2018","journal-title":"Ann Med"},{"key":"10.1016\/j.ajog.2020.02.029_bib21","first-page":"620","article-title":"Human papillomavirus vaccination coverage among adolescents, 2007-2013, and postlicensure vaccine safety monitoring, 2006-2014\u2500United States","volume":"63","author":"Stokley","year":"2014","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.ajog.2020.02.029_bib22","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.pvr.2018.10.010","article-title":"Changes in human papillomavirus genotypes associated with cervical intraepithelial neoplasia grade 2 lesions in a cohort of young women (2013-2016)","volume":"6","author":"Innes","year":"2018","journal-title":"Papillomavirus Res"},{"key":"10.1016\/j.ajog.2020.02.029_bib23","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1097\/AOG.0b013e3181fe777f","article-title":"Rate of and risks for regression of cervical intraepithelial neoplasia 2 in adolescents and young women","volume":"116","author":"Moscicki","year":"2010","journal-title":"Obstet Gynecol"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937820302179?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937820302179?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T19:25:25Z","timestamp":1788463525000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937820302179"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["S0002937820302179"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2020.02.029","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of guidelines for observational management of cervical intraepithelial neoplasia 2 in young women","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2020.02.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}