{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T07:55:20Z","timestamp":1793433320083,"version":"4.5.0"},"reference-count":85,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1016\/j.ajog.2020.03.006","type":"journal-article","created":{"date-parts":[[2020,3,14]],"date-time":"2020-03-14T11:25:50Z","timestamp":1584185150000},"page":"516-524","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":527,"title":["Iron deficiency in pregnancy"],"prefix":"10.1016","volume":"223","author":[{"given":"Michael K.","family":"Georgieff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"suppl","key":"10.1016\/j.ajog.2020.03.006_bib1","doi-asserted-by":"crossref","first-page":"1567S","DOI":"10.3945\/ajcn.117.155812","article-title":"Iron homeostasis during pregnancy","volume":"106","author":"Fisher","year":"2017","journal-title":"Am J Clin Nutr"},{"issue":"suppl","key":"10.1016\/j.ajog.2020.03.006_bib2","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1002\/(SICI)1096-8644(1998)107:27+<177::AID-AJPA7>3.0.CO;2-B","article-title":"Adipose tissue in human infancy and childhood: an evolutionary perspective","volume":"27","author":"Kuzawa","year":"1998","journal-title":"Am J Phys Anthropol"},{"key":"10.1016\/j.ajog.2020.03.006_bib3","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/scientificamerican0979-112","article-title":"The development of the brain","volume":"241","author":"Cowan","year":"1979","journal-title":"Sci Am"},{"key":"10.1016\/j.ajog.2020.03.006_bib4","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1037\/0003-066X.56.1.5","article-title":"Developmental science and the media. Early brain development","volume":"56","author":"Thompson","year":"2001","journal-title":"Am Psychol"},{"key":"10.1016\/j.ajog.2020.03.006_bib6","first-page":"1","article-title":"Prevalence of iron deficiency in first trimester, nonanemic pregnant women","volume":"3","author":"Auerbach","year":"2019","journal-title":"J\u00a0Matern Fetal Neonatal Med"},{"key":"10.1016\/j.ajog.2020.03.006_bib7","series-title":"Hematologic problems in the newborn","first-page":"32","article-title":"The hematologic aspects of the maternal-fetal relationship","author":"Oski","year":"1982"},{"key":"10.1016\/j.ajog.2020.03.006_bib8","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/j.1753-4887.2012.00550.x","article-title":"Pregnancy and iron homeostasis: an update","volume":"71","author":"Cao","year":"2013","journal-title":"Nutr Rev"},{"key":"10.1016\/j.ajog.2020.03.006_bib9","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1017\/S0029665113003637","article-title":"Iron deficiency during pregnancy: the consequences for placental function and fetal outcome","volume":"73","author":"McArdle","year":"2014","journal-title":"Proc Nutr Soc"},{"issue":"suppl","key":"10.1016\/j.ajog.2020.03.006_bib10","doi-asserted-by":"crossref","first-page":"1663S","DOI":"10.3945\/ajcn.117.156018","article-title":"Iron status of young children in Europe","volume":"106","author":"van der Merwe","year":"2017","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib11","doi-asserted-by":"crossref","first-page":"E330","DOI":"10.3390\/nu8060330","article-title":"Iron, anemia and iron deficiency anemia among young children in the United States","volume":"8","author":"Gupta","year":"2016","journal-title":"Nutrients"},{"key":"10.1016\/j.ajog.2020.03.006_bib12","doi-asserted-by":"crossref","first-page":"S34","DOI":"10.1301\/nr.2006.may.S34-S43","article-title":"Long-lasting neural and behavioral effects of early iron deficiency in infancy","volume":"64","author":"Lozoff","year":"2006","journal-title":"Nutr Rev"},{"key":"10.1016\/j.ajog.2020.03.006_bib13","first-page":"2004","article-title":"Maternal serum ferritin concentration is positively associated with newborn iron stores in women with low ferritin status in late pregnancy","volume":"142","author":"Shao","year":"2012","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib14","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1067\/mpd.2002.120688","article-title":"Cord serum ferritin concentrations and mental and psychomotor development of children at five years of age","volume":"140","author":"Tamura","year":"2002","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.ajog.2020.03.006_bib15","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1203\/01.pdr.0000127021.38207.62","article-title":"Auditory recognition memory in iron-deficient infants of diabetic mothers","volume":"55","author":"Siddappa","year":"2004","journal-title":"Pediatr Res"},{"key":"10.1016\/j.ajog.2020.03.006_bib16","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jpeds.2009.09.049","article-title":"In utero iron status and auditory neural maturation in premature infants as evaluated by auditory brainstem response","volume":"156","author":"Amin","year":"2010","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.ajog.2020.03.006_bib17","article-title":"Timing of iron deficiency and recognition memory in infancy","author":"Geng","year":"2020","journal-title":"Nutr Neurosci"},{"key":"10.1016\/j.ajog.2020.03.006_bib18","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1080\/87565640903265145","article-title":"Consequences of low neonatal iron status due to maternal diabetes mellitus on explicit memory performance in childhood","volume":"34","author":"Riggins","year":"2009","journal-title":"Dev Neuropsychol"},{"key":"10.1016\/j.ajog.2020.03.006_bib19","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1097\/DBP.0000000000000203","article-title":"Functional and anatomic consequences of diabetic pregnancy on memory in 10-year-old children","volume":"36","author":"Jab\u00e8s","year":"2015","journal-title":"J\u00a0Dev Behav Pediatr"},{"key":"10.1016\/j.ajog.2020.03.006_bib20","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1067\/mpd.2002.127090","article-title":"Iron status at 9 months of infants with low iron stores at birth","volume":"141","author":"Georgieff","year":"2002","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.ajog.2020.03.006_bib21","first-page":"1916","article-title":"Prenatal iron supplementation reduces maternal anemia, iron deficiency, iron deficiency anemia in a randomized clinical trial in rural china, but iron deficiency remains widespread in mothers and neonates","volume":"145","author":"Zhao","year":"2015","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib22","first-page":"329","article-title":"Body composition of the reference fetus","volume":"40","author":"Ziegler","year":"1976","journal-title":"Growth"},{"key":"10.1016\/j.ajog.2020.03.006_bib23","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1159\/000353161","article-title":"A\u00a0review of cord blood concentrations of iron status parameters to define reference ranges for preterm infants","volume":"104","author":"Lorenz","year":"2013","journal-title":"Neonatology"},{"key":"10.1016\/j.ajog.2020.03.006_bib24","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1093\/ajcn\/77.4.924","article-title":"Maternal iron status influences iron transfer to the fetus during the third trimester of pregnancy","volume":"77","author":"O\u2019Brien","year":"2003","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib25","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1111\/j.1651-2227.1978.tb16254.x","article-title":"Serum ferritin in assessment of iron nutrition in healthy infants","volume":"67","author":"Saarinen","year":"1978","journal-title":"Acta Paediatr Scand"},{"key":"10.1016\/j.ajog.2020.03.006_bib26","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1159\/000100805","article-title":"The assessment of newborn iron stores at birth: a review of the literature and standards for ferritin concentrations","volume":"92","author":"Siddappa","year":"2007","journal-title":"Neonatology"},{"key":"10.1016\/j.ajog.2020.03.006_bib27","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S0022-3476(87)80088-4","article-title":"Cord transferrin and ferritin levels in newborn infants at risk for prenatal uteroplacental insufficiency and chronic hypoxia","volume":"111","author":"Chockalingam","year":"1987","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.ajog.2020.03.006_bib28","doi-asserted-by":"crossref","first-page":"F40","DOI":"10.1136\/fn.84.1.F40","article-title":"Study of maternal influences on fetal iron status at term using cord blood transferrin receptors","volume":"84","author":"Sweet","year":"2001","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.ajog.2020.03.006_bib29","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/S0022-3476(05)81097-2","article-title":"Abnormal iron distribution in infants of diabetic mothers: spectrum and maternal antecedents","volume":"117","author":"Georgieff","year":"1990","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.ajog.2020.03.006_bib30","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0022-3476(05)82554-5","article-title":"Iron deficiency of liver, heart, and brain in newborn infants of diabetic mothers","volume":"121","author":"Petry","year":"1992","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.ajog.2020.03.006_bib31","first-page":"1716","article-title":"Umbilical cord hepcidin concentrations are positively associated with the variance in iron status among multiple birth neonates","volume":"148","author":"Ru","year":"2018","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib32","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1161\/01.RES.39.5.744","article-title":"The effects of iron deficiency on the respiratory function and cytochrome content of rat heart mitochondria","volume":"39","author":"Blayney","year":"1976","journal-title":"Circ Res"},{"key":"10.1016\/j.ajog.2020.03.006_bib33","first-page":"672","article-title":"Iron is essential for neuron development and memory function in mouse hippocampus","volume":"139","author":"Carlson","year":"2009","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib34","doi-asserted-by":"crossref","first-page":"1588S","DOI":"10.3945\/ajcn.117.155846","article-title":"Iron assessment to protect the developing brain","volume":"106","author":"Georgieff","year":"2017","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib35","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1038\/pr.2016.20","article-title":"Iron is prioritized to red blood cells over the brain in phlebotomized anemic newborn lambs","volume":"79","author":"Zamora","year":"2016","journal-title":"Pediatr Res"},{"key":"10.1016\/j.ajog.2020.03.006_bib36","first-page":"1","article-title":"Metabolomic analysis of CSF indicates brain metabolic impairment precedes hematological indices of anemia in the iron-deficient infant monkey","volume":"6","author":"Rao","year":"2016","journal-title":"Nutr Neurosci"},{"key":"10.1016\/j.ajog.2020.03.006_bib37","first-page":"R485","article-title":"Fetal iron and cytochrome c status after intrauterine hypoxemia and erythropoietin administration","volume":"262","author":"Georgieff","year":"1992","journal-title":"Am J Physiol"},{"key":"10.1016\/j.ajog.2020.03.006_bib38","doi-asserted-by":"crossref","first-page":"1681S","DOI":"10.3945\/ajcn.117.156042","article-title":"Excess iron intake as a factor in growth, infections, and development of infants and young children","volume":"106","author":"Lonnerdal","year":"2017","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib39","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1093\/ajcn\/65.2.425","article-title":"Delayed clamping of the umbilical cord improves hematologic status of Guatemalan infants at 2 mo of age","volume":"65","author":"Grajeda","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib40","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.freeradbiomed.2018.10.411","article-title":"The ins and outs of iron: escorting iron through the mammalian cytosol","volume":"133","author":"Philpott","year":"2019","journal-title":"Free Rad Biol Med"},{"key":"10.1016\/j.ajog.2020.03.006_bib41","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1093\/clinchem\/44.1.45","article-title":"Clinical utility of the soluble transferrin receptor and comparison with serum ferritin in several populations","volume":"44","author":"Mast","year":"1998","journal-title":"Clin Chem"},{"key":"10.1016\/j.ajog.2020.03.006_bib42","doi-asserted-by":"crossref","first-page":"1626S","DOI":"10.3945\/ajcn.117.155937","article-title":"Assessment of iron status in settings of inflammation: challenges and potential approaches","volume":"106","author":"Suchdev","year":"2017","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib43","doi-asserted-by":"crossref","first-page":"12727","DOI":"10.1074\/jbc.R117.781823","article-title":"Iron homeostasis: an anthropocentric perspective","volume":"292","author":"Coffey","year":"2017","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.ajog.2020.03.006_bib44","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/j.jpeds.2007.09.048","article-title":"Dose-response relationships between iron deficiency with or without anemia and infant social-emotional behavior","volume":"152","author":"Lozoff","year":"2008","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.ajog.2020.03.006_bib45","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1002\/hipo.22004","article-title":"Temporal manipulation of transferrin receptor-1 dependent iron uptake identifies a sensitive period in mouse hippocampal neurodevelopment","volume":"22","author":"Fretham","year":"2012","journal-title":"Hippocampus"},{"key":"10.1016\/j.ajog.2020.03.006_bib46","doi-asserted-by":"crossref","first-page":"1694S","DOI":"10.3945\/ajcn.117.156075","article-title":"U-shaped curve for risk associated with maternal hemoglobin, iron status or iron supplementation","volume":"106","author":"Dewey","year":"2017","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib47","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1146\/annurev-nutr-082018-124213","article-title":"The benefits and risks of iron supplementation in pregnancy and childhood","volume":"39","author":"Georgieff","year":"2019","journal-title":"Ann Rev Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib48","doi-asserted-by":"crossref","first-page":"1703S","DOI":"10.3945\/ajcn.117.156083","article-title":"Integrating themes, evidence gaps, and research needs identified by workshop on iron screening and supplementation in iron-replete pregnant women and young children","volume":"106","author":"Brannon","year":"2017","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib49","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0140-6736(07)60076-2","article-title":"Child development: risk factors for adverse outcomes in developing countries","volume":"369","author":"Walker","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.ajog.2020.03.006_bib50","doi-asserted-by":"crossref","first-page":"529","DOI":"10.7326\/M15-1707","article-title":"Screening for iron deficiency anemia and iron supplementation in pregnant women to improve maternal health and birth outcomes: US Preventative Services Task Force Recommendation Statement","volume":"163","author":"Siu","year":"2015","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ajog.2020.03.006_bib51","doi-asserted-by":"crossref","first-page":"1672S","DOI":"10.3945\/ajcn.117.156034","article-title":"Dietary iron intake, iron status and gestational diabetes","volume":"106","author":"Zhang","year":"2017","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib52","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1038\/pr.2015.248","article-title":"Maternal prenatal iron status and tissue organization in the neonatal brain","volume":"79","author":"Monk","year":"2015","journal-title":"Pediatr Res"},{"key":"10.1016\/j.ajog.2020.03.006_bib53","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1016\/j.jpeds.2015.08.035","article-title":"Impact of fetal-neonatal iron deficiency on recognition memory at 2 months of age","volume":"167","author":"Geng","year":"2015","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.ajog.2020.03.006_bib54","doi-asserted-by":"crossref","first-page":"99R","DOI":"10.1203\/01.PDR.0000160542.69840.0F","article-title":"Controversial nutrients in the perinatal period that potentially affect neurodevelopment: essential fatty acids and iron","volume":"57","author":"Georgieff","year":"2005","journal-title":"Pediatr Res"},{"key":"10.1016\/j.ajog.2020.03.006_bib55","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1093\/ajcn\/68.3.683","article-title":"Evidence of altered central nervous system development in infants with iron deficiency anemia at 6 mo: delayed maturation of auditory brainstem responses","volume":"68","author":"Roncagliolo","year":"1998","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib56","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0378-3782(02)00092-0","article-title":"Twenty-four-hour motor activity in human infants with and without iron deficiency anemia","volume":"70","author":"Angulo-Kinzler","year":"2002","journal-title":"Early Hum Dev"},{"key":"10.1016\/j.ajog.2020.03.006_bib57","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1001\/archpedi.160.11.1108","article-title":"Double burden of iron deficiency in infancy and low socioeconomic status: a longitudinal analysis of cognitive test scores to age 19 years","volume":"160","author":"Lozoff","year":"2006","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.ajog.2020.03.006_bib58","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1179\/147683010X12611460763689","article-title":"Iron deficiency in infancy and neurocognitive functioning at 19 years: evidence of long-term deficits in executive function and recognition memory","volume":"13","author":"Lukowski","year":"2010","journal-title":"Nutr Neurosci"},{"key":"10.1016\/j.ajog.2020.03.006_bib59","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1093\/aje\/kwu208","article-title":"Maternal intake of supplemental iron and risk of autism spectrum disorder","volume":"180","author":"Schmidt","year":"2014","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.ajog.2020.03.006_bib60","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1001\/archpsyc.65.10.1136","article-title":"Maternal iron and the risk of schizophrenia in offspring","volume":"65","author":"Insel","year":"2008","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.ajog.2020.03.006_bib61","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1203\/01.PDR.0000047657.23156.55","article-title":"Iron deficiency anemia in infancy: long-lasting effects on auditory and visual system functioning","volume":"53","author":"Algarin","year":"2003","journal-title":"Pediatr Res"},{"key":"10.1016\/j.ajog.2020.03.006_bib62","first-page":"491","article-title":"The neurochemical basis of cognitive deficits induced by brain iron deficiency: involvement of dopamine-opiate system","volume":"46","author":"Youdim","year":"2000","journal-title":"Cell Mol Biol"},{"key":"10.1016\/j.ajog.2020.03.006_bib63","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.bbr.2006.04.001","article-title":"Persistent neurochemical and behavioral abnormalities in adulthood despite early iron supplementation for perinatal iron deficiency anemia in rats","volume":"171","author":"Felt","year":"2006","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.ajog.2020.03.006_bib64","first-page":"3215","article-title":"Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus","volume":"133","author":"Rao","year":"2003","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib65","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1159\/000448514","article-title":"Iron deficiency impairs developing hippocampal neuron gene expression, energy metabolism and dendrite complexity","volume":"38","author":"Bastian","year":"2016","journal-title":"Dev Neurosci"},{"key":"10.1016\/j.ajog.2020.03.006_bib66","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1002\/jnr.20207","article-title":"Effect of manipulation of iron storage, transport, or availability on myelin composition and brain iron content in three different animal models","volume":"77","author":"Ortiz","year":"2004","journal-title":"J\u00a0Neurosci Res"},{"key":"10.1016\/j.ajog.2020.03.006_bib67","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1002\/hipo.20307","article-title":"Perinatal iron deficiency results in altered developmental expression of genes mediating energy metabolism and neuronal morphogenesis in hippocampus","volume":"17","author":"Carlson","year":"2007","journal-title":"Hippocampus"},{"key":"10.1016\/j.ajog.2020.03.006_bib68","first-page":"173","article-title":"Acute and chronic effects of developmental iron deficiency on mRNA expression patterns in the brain","volume":"71","author":"Clardy","year":"2006","journal-title":"J\u00a0Neural Transm Suppl"},{"key":"10.1016\/j.ajog.2020.03.006_bib69","first-page":"484","article-title":"Prenatal choline supplementation diminishes early \u2013life iron deficiency induced preprogramming of networks associated with behavioral abnormalities in the adult rat hippocampus","volume":"146","author":"Tran","year":"2016","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib70","first-page":"2040","article-title":"Behavior and monoamine deficits in pre- and peri-natal iron deficiency are not corrected by early postnatal moderate or high iron diet in rats","volume":"142","author":"Unger","year":"2012","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib71","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/dev.20049","article-title":"Relation of neonatal iron status to individual variability in neonatal temperament","volume":"46","author":"Wachs","year":"2005","journal-title":"Dev Psychobiol"},{"key":"10.1016\/j.ajog.2020.03.006_bib72","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1523\/JNEUROSCI.1504-18.2018","article-title":"Chronic energy depletion due to iron deficiency impairs dendritic mitochondrial motility during hippocampal neuron development","volume":"39","author":"Bastian","year":"2019","journal-title":"J.\u00a0Neurosci"},{"key":"10.1016\/j.ajog.2020.03.006_bib73","first-page":"2495","article-title":"Early-life iron deficiency anemia alters neurotrophic factor expression and hippocampal neuron differentiation in male rats","volume":"138","author":"Tran","year":"2008","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.ajog.2020.03.006_bib74","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1159\/000314341","article-title":"Gestational and neonatal iron deficiency alters apical dendrite structure of CA1 pyramidal neurons in adult rat hippocampus","volume":"32","author":"Brunette","year":"2010","journal-title":"Dev Neurosci"},{"key":"10.1016\/j.ajog.2020.03.006_bib75","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1002\/hipo.20128","article-title":"Fetal iron deficiency disrupts the maturation of synaptic function and efficacy in area CA1 of the developing rat hippocampus","volume":"15","author":"Jorgenson","year":"2005","journal-title":"Hippocampus"},{"key":"10.1016\/j.ajog.2020.03.006_bib76","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1002\/hipo.22151","article-title":"Iron deficiency with or without anemia impairs prepulse inhibition of the startle reflex","volume":"23","author":"Pisansky","year":"2013","journal-title":"Hippocampus"},{"key":"10.1016\/j.ajog.2020.03.006_bib77","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1203\/PDR.0b013e31819d90a1","article-title":"Long-term reduction of hippocampal BDNF activity following fetal-neonatal iron deficiency in adult rats","volume":"65","author":"Tran","year":"2009","journal-title":"Pediatr Res"},{"key":"10.1016\/j.ajog.2020.03.006_bib78","doi-asserted-by":"crossref","first-page":"R276","DOI":"10.1152\/ajpregu.00429.2014","article-title":"Fetal iron deficiency induces chromatin remodeling at the Bdnf locus in adult rat hippocampus","volume":"308","author":"Tran","year":"2015","journal-title":"Am J Physiol Integr Comp Phys"},{"key":"10.1016\/j.ajog.2020.03.006_bib79","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1146\/annurev.neuro.27.070203.144327","article-title":"Critical period regulation","volume":"27","author":"Hensch","year":"2004","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/j.ajog.2020.03.006_bib80","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1159\/000075667","article-title":"Perinatal iron deficiency alters apical dendritic growth in hippocampal CA-1 pyramidal neurons","volume":"25","author":"Jorgenson","year":"2003","journal-title":"Dev Neurosci"},{"key":"10.1016\/j.ajog.2020.03.006_bib81","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1017\/S2040174419000205","article-title":"DOHaD\u2014the challenge of translating science to policy","volume":"10","author":"Hanson","year":"2019","journal-title":"J\u00a0Dev Orig Health Dis"},{"key":"10.1016\/j.ajog.2020.03.006_bib82","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/s41390-018-0204-8","article-title":"Iron as a model nutrient for understanding the nutritional origins of neuropsychiatric disease","volume":"85","author":"Barks","year":"2019","journal-title":"Pediatr Res"},{"key":"10.1016\/j.ajog.2020.03.006_bib83","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1161\/01.CIR.94.6.1310","article-title":"Birth weight and adult hypertension and obesity in women","volume":"94","author":"Curran","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.ajog.2020.03.006_bib84","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.biopsych.2010.05.028","article-title":"Early life programming and neurodevelopmental disorders","volume":"68","author":"Bale","year":"2010","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.ajog.2020.03.006_bib85","doi-asserted-by":"crossref","first-page":"e53","DOI":"10.1136\/eb-2013-101311","article-title":"Maternal folic acid supplements associated with reduced autism risk in the child","volume":"18","author":"Schmidt","year":"2013","journal-title":"Evid Based Med"},{"key":"10.1016\/j.ajog.2020.03.006_bib86","doi-asserted-by":"crossref","first-page":"194","DOI":"10.3389\/fnins.2015.00194","article-title":"The role of maternal obesity in the risk of neuropsychiatric disorders","volume":"9","author":"Rivera","year":"2015","journal-title":"Front Neurosci"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937820303288?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937820303288?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T11:30:51Z","timestamp":1757590251000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937820303288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":85,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["S0002937820303288"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2020.03.006","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Iron deficiency in pregnancy","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2020.03.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}