{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:54:10Z","timestamp":1792803250453,"version":"4.5.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,3,16]],"date-time":"2021-03-16T00:00:00Z","timestamp":1615852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008736","name":"Marta Lundqvist Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008736","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007687","name":"Swedish Society of Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007687","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004060","name":"Preeclampsia Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003748","name":"Swedish Society for Medical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003748","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.ajog.2021.03.017","type":"journal-article","created":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T17:37:00Z","timestamp":1616002620000},"page":"185.e1-185.e9","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"title":["Cerebral perfusion pressure and autoregulation in eclampsia\u2014a case control study"],"prefix":"10.1016","volume":"225","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5202-9428","authenticated-orcid":false,"given":"Lina","family":"Bergman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Cluver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niclas","family":"Carlberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Belfort","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary C.","family":"Tolcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronney B.","family":"Panerai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teelkien","family":"van Veen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2021.03.017_bib1","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/S0140-6736(15)00070-7","article-title":"Pre-eclampsia","volume":"387","author":"Mol","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.ajog.2021.03.017_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejogrb.2013.05.005","article-title":"Global and regional estimates of preeclampsia and eclampsia: a systematic review","volume":"170","author":"Abalos","year":"2013","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ajog.2021.03.017_bib3","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1053\/j.semperi.2009.02.010","article-title":"The global impact of pre-eclampsia and eclampsia","volume":"33","author":"Duley","year":"2009","journal-title":"Semin Perinatol"},{"key":"10.1016\/j.ajog.2021.03.017_bib4","doi-asserted-by":"crossref","first-page":"k4109","DOI":"10.1136\/bmj.k4109","article-title":"Pre-eclampsia and risk of dementia later in life: nationwide cohort study","volume":"363","author":"Basit","year":"2018","journal-title":"BMJ"},{"key":"10.1016\/j.ajog.2021.03.017_bib5","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1097\/AOG.0000000000002364","article-title":"Long-term risk of a seizure disorder after eclampsia","volume":"130","author":"Nerenberg","year":"2017","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2021.03.017_bib6","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.ahj.2008.06.042","article-title":"Cardiovascular sequelae of preeclampsia\/eclampsia: a systematic review and meta-analyses","volume":"156","author":"McDonald","year":"2008","journal-title":"Am Heart J"},{"key":"10.1016\/j.ajog.2021.03.017_bib7","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1007\/s11906-019-0977-0","article-title":"Investigating maternal brain alterations in preeclampsia: the need for a multidisciplinary effort","volume":"21","author":"Bergman","year":"2019","journal-title":"Curr Hypertens Rep"},{"key":"10.1016\/j.ajog.2021.03.017_bib8","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/S0002-9378(99)70569-7","article-title":"Change in estimated cerebral perfusion pressure after treatment with nimodipine or magnesium sulfate in patients with preeclampsia","volume":"181","author":"Belfort","year":"1999","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2021.03.017_bib9","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1081\/PRG-120015845","article-title":"Labetalol decreases cerebral perfusion pressure without negatively affecting cerebral blood flow in hypertensive gravidas","volume":"21","author":"Belfort","year":"2002","journal-title":"Hypertens Pregnancy"},{"key":"10.1016\/j.ajog.2021.03.017_bib10","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1081\/PRG-100101995","article-title":"Evaluation of a noninvasive transcranial Doppler and blood pressure-based method for the assessment of cerebral perfusion pressure in pregnant women","volume":"19","author":"Belfort","year":"2000","journal-title":"Hypertens Pregnancy"},{"key":"10.1016\/j.ajog.2021.03.017_bib11","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1097\/AOG.0b013e3182a93fb5","article-title":"Cerebral autoregulation in normal pregnancy and preeclampsia","volume":"122","author":"van Veen","year":"2013","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2021.03.017_bib12","first-page":"1","article-title":"ACOG Practice Bulletin no. 202: gestational hypertension and preeclampsia","volume":"133","year":"2019","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2021.03.017_bib13","doi-asserted-by":"crossref","first-page":"103208","DOI":"10.1016\/j.jbi.2019.103208","article-title":"The REDCap consortium: building an international community of software platform partners","volume":"95","author":"Harris","year":"2019","journal-title":"J\u00a0Biomed Inform"},{"key":"10.1016\/j.ajog.2021.03.017_bib14","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1161\/01.STR.29.11.2341","article-title":"Grading of cerebral dynamic autoregulation from spontaneous fluctuations in arterial blood pressure","volume":"29","author":"Panerai","year":"1998","journal-title":"Stroke"},{"key":"10.1016\/j.ajog.2021.03.017_bib15","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1177\/0271678X15626425","article-title":"Transfer function analysis of dynamic cerebral autoregulation: a white paper from the International Cerebral Autoregulation Research Network","volume":"36","author":"Claassen","year":"2016","journal-title":"J\u00a0Cereb Blood Flow Metab"},{"key":"10.1016\/j.ajog.2021.03.017_bib16","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1161\/01.STR.26.6.1014","article-title":"Comparison of static and dynamic cerebral autoregulation measurements","volume":"26","author":"Tiecks","year":"1995","journal-title":"Stroke"},{"key":"10.1016\/j.ajog.2021.03.017_bib17","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1080\/02688690400012343","article-title":"Association between dynamic cerebral autoregulation and mortality in severe head injury","volume":"18","author":"Panerai","year":"2004","journal-title":"Br J Neurosurg"},{"key":"10.1016\/j.ajog.2021.03.017_bib18","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1159\/000093810","article-title":"Cerebral hemodynamics and autoregulation in reversible posterior leukoencephalopathy syndrome caused by pre-\/eclampsia","volume":"22","author":"Oehm","year":"2006","journal-title":"Cerebrovasc Dis"},{"key":"10.1016\/j.ajog.2021.03.017_bib19","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1177\/0271678X19871013","article-title":"Assessment of cerebral autoregulation in stroke: a systematic review and meta-analysis of studies at rest","volume":"39","author":"Intharakham","year":"2019","journal-title":"J\u00a0Cereb Blood Flow Metab"},{"key":"10.1016\/j.ajog.2021.03.017_bib20","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1034\/j.1600-0412.1999.780705.x","article-title":"Preeclampsia may cause both overperfusion and underperfusion of the brain: a cerebral perfusion based model","volume":"78","author":"Belfort","year":"1999","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.ajog.2021.03.017_bib21","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1111\/j.1471-0528.1999.tb08403.x","article-title":"Association of cerebral perfusion pressure with headache in women with pre-eclampsia","volume":"106","author":"Belfort","year":"1999","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.ajog.2021.03.017_bib22","doi-asserted-by":"crossref","first-page":"441.e1","DOI":"10.1016\/j.ajog.2020.06.018","article-title":"Intravenous labetalol versus oral nifedipine for acute hypertension in pregnancy: effects on cerebral perfusion pressure","volume":"223","author":"Tolcher","year":"2020","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2021.03.017_bib23","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0113670","article-title":"Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia","volume":"9","author":"Johnson","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ajog.2021.03.017_bib24","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1080\/10641950801955683","article-title":"Magnesium sulfate decreases cerebral perfusion pressure in preeclampsia","volume":"27","author":"Belfort","year":"2008","journal-title":"Hypertens Pregnancy"},{"key":"10.1016\/j.ajog.2021.03.017_bib25","doi-asserted-by":"crossref","first-page":"10554","DOI":"10.1038\/s41598-020-67404-9","article-title":"Cerebral autoregulation and response to intravenous thrombolysis for acute ischemic stroke","volume":"10","author":"Nogueira","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.ajog.2021.03.017_bib26","doi-asserted-by":"crossref","first-page":"R108","DOI":"10.1152\/ajpregu.00361.2016","article-title":"Cerebral blood flow autoregulation in ischemic heart failure","volume":"312","author":"Caldas","year":"2017","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.ajog.2021.03.017_bib27","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1080\/00016340600607149","article-title":"Eclampsia in Scandinavia: incidence, substandard care, and potentially preventable cases","volume":"85","author":"Andersgaard","year":"2006","journal-title":"Acta Obstet Gynecol Scand"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937821001691?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937821001691?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T11:33:18Z","timestamp":1757590398000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937821001691"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["S0002937821001691"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2021.03.017","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cerebral perfusion pressure and autoregulation in eclampsia\u2014a case control study","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2021.03.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}