{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T17:42:00Z","timestamp":1788975720425,"version":"build-2803163510"},"reference-count":23,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.ajog.2021.03.041","type":"journal-article","created":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T16:33:32Z","timestamp":1617294812000},"page":"305.e1-305.e14","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Angiogenic markers and their longitudinal change for predicting adverse outcomes in pregnant women with chronic hypertension"],"prefix":"10.1016","volume":"225","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5725-9270","authenticated-orcid":false,"given":"Julia","family":"Binder","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erkan","family":"Kalafat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Palmrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Pateisky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asma","family":"Khalil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2021.03.041_bib1","doi-asserted-by":"crossref","first-page":"e323","DOI":"10.1016\/S2214-109X(14)70227-X","article-title":"Global causes of maternal death: a WHO systematic analysis","volume":"2","author":"Say","year":"2014","journal-title":"Lancet Glob Health"},{"key":"10.1016\/j.ajog.2021.03.041_bib2","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1097\/AOG.0b013e3181a45b25","article-title":"Hypertensive disorders and severe obstetric morbidity in the United States","volume":"113","author":"Kuklina","year":"2009","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2021.03.041_bib3","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1111\/j.1600-0412.2011.01111.x","article-title":"How accurate are maternal symptoms in predicting impending complications in women with preeclampsia? A systematic review and meta-analysis","volume":"90","author":"Thangaratinam","year":"2011","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.ajog.2021.03.041_bib4","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/j.1471-0528.2006.00908.x","article-title":"Accuracy of serum uric acid in predicting complications of pre-eclampsia: a systematic review","volume":"113","author":"Thangaratinam","year":"2006","journal-title":"BJOG"},{"key":"10.1016\/j.ajog.2021.03.041_bib5","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1741-7015-7-10","article-title":"Estimation of proteinuria as a predictor of complications of pre-eclampsia: a systematic review","volume":"7","author":"Thangaratinam","year":"2009","journal-title":"BMC Med"},{"key":"10.1016\/j.ajog.2021.03.041_bib6","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1161\/HYPERTENSIONAHA.119.13997","article-title":"Angiogenic marker prognostic models in pregnant women with hypertension","volume":"75","author":"Perry","year":"2020","journal-title":"Hypertension"},{"key":"10.1016\/j.ajog.2021.03.041_bib7","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1161\/HYPERTENSIONAHA.120.15146","article-title":"Prediction of preeclampsia-related adverse outcomes with the sFlt-1 (soluble fms-like tyrosine kinase 1)\/PlGF (placental growth factor)-ratio in the clinical routine: a real-world study","volume":"77","author":"Dr\u00f6ge","year":"2021","journal-title":"Hypertension"},{"key":"10.1016\/j.ajog.2021.03.041_bib8","article-title":"Impact of new definitions of preeclampsia at term on identification of adverse maternal and perinatal outcomes","author":"Lai","year":"2020","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2021.03.041_bib9","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1080\/10641955.2020.1769643","article-title":"Predisposition to superimposed preeclampsia in women with chronic hypertension: endothelial, renal, cardiac, and placental factors in a prospective longitudinal cohort","volume":"39","author":"Bramham","year":"2020","journal-title":"Hypertens Pregnancy"},{"key":"10.1016\/j.ajog.2021.03.041_bib10","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.preghy.2018.10.006","article-title":"Severe hypertension, preeclampsia and small for gestational age in women with chronic hypertension diagnosed before and during pregnancy","volume":"14","author":"Nzelu","year":"2018","journal-title":"Pregnancy Hypertens"},{"key":"10.1016\/j.ajog.2021.03.041_bib11","doi-asserted-by":"crossref","first-page":"g2301","DOI":"10.1136\/bmj.g2301","article-title":"Chronic hypertension and pregnancy outcomes: systematic review and meta-analysis","volume":"348","author":"Bramham","year":"2014","journal-title":"BMJ"},{"key":"10.1016\/j.ajog.2021.03.041_bib12","article-title":"Toward personalized management of chronic hypertension in pregnancy","author":"Magee","year":"2020","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2021.03.041_bib13","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1002\/uog.17493","article-title":"Chronic hypertension and adverse pregnancy outcome: a cohort study","volume":"50","author":"Panaitescu","year":"2017","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajog.2021.03.041_bib14","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1161\/HYPERTENSIONAHA.111.181735","article-title":"Angiogenic factors in superimposed preeclampsia: a longitudinal study of women with chronic hypertension during pregnancy","volume":"59","author":"Perni","year":"2012","journal-title":"Hypertension"},{"key":"10.1016\/j.ajog.2021.03.041_bib15","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.preghy.2020.09.007","article-title":"Role of sFlt-1\/PIGF ratio and uterine Doppler in pregnancies with chronic kidney disease suspected with Pre-eclampsia or HELLP syndrome","volume":"22","author":"Karge","year":"2020","journal-title":"Pregnancy Hypertens"},{"key":"10.1016\/j.ajog.2021.03.041_bib16","doi-asserted-by":"crossref","first-page":"139","DOI":"10.3109\/10641955.2015.1115063","article-title":"Preeclampsia and superimposed preeclampsia: the same disease? The role of angiogenic biomarkers","volume":"35","author":"Costa","year":"2016","journal-title":"Hypertens Pregnancy"},{"key":"10.1016\/j.ajog.2021.03.041_bib17","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1161\/HYPERTENSIONAHA.117.10803","article-title":"Hypertensive disorders of pregnancy: ISSHP classification, diagnosis, and management recommendations for international practice","volume":"72","author":"Brown","year":"2018","journal-title":"Hypertension"},{"key":"10.1016\/j.ajog.2021.03.041_bib18","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.preghy.2020.06.005","article-title":"Standardising definitions for the pre-eclampsia core outcome set: a consensus development study","volume":"21","author":"Duffy","year":"2020","journal-title":"Pregnancy Hypertens"},{"key":"10.1016\/j.ajog.2021.03.041_bib19","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1055\/a-0582-0122","article-title":"Peripartum haemorrhage, diagnosis and therapy. Guideline of the DGGG, OEGGG and SGGG (S2k level, AWMF registry no. 015\/063, March 2016)","volume":"78","author":"Schlembach","year":"2018","journal-title":"Geburtshilfe Frauenheilkd"},{"key":"10.1016\/j.ajog.2021.03.041_bib20","doi-asserted-by":"crossref","first-page":"374.e1","DOI":"10.1016\/j.ajog.2019.10.101","article-title":"First trimester serum angiogenic and anti-angiogenic factors in women with chronic hypertension for the prediction of preeclampsia","volume":"222","author":"Nzelu","year":"2020","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2021.03.041_bib21","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1161\/HYPERTENSIONAHA.119.14627","article-title":"Maternal and perinatal outcomes of white coat hypertension during pregnancy: a systematic review and meta-analysis","volume":"76","author":"Johnson","year":"2020","journal-title":"Hypertension"},{"key":"10.1016\/j.ajog.2021.03.041_bib22","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.preghy.2019.12.001","article-title":"Home blood pressure monitoring in the antenatal and postpartum period: a systematic review meta-analysis","volume":"19","author":"Kalafat","year":"2020","journal-title":"Pregnancy Hypertens"},{"key":"10.1016\/j.ajog.2021.03.041_bib23","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1161\/HYPERTENSIONAHA.120.14982","article-title":"Prognostic value of maternal cardiovascular hemodynamics in women with gestational hypertension and chronic hypertension in Pregnancy","volume":"76","author":"Kalafat","year":"2020","journal-title":"Hypertension"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937821002209?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937821002209?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T11:35:02Z","timestamp":1757590502000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937821002209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S0002937821002209"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2021.03.041","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Angiogenic markers and their longitudinal change for predicting adverse outcomes in pregnant women with chronic hypertension","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2021.03.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}