{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:30:08Z","timestamp":1786984208654,"version":"build-2736575974"},"reference-count":89,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T00:00:00Z","timestamp":1711670400000},"content-version":"am","delay-in-days":363,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000060","name":"NIAID","doi-asserted-by":"publisher","award":["AI143265"],"award-info":[{"award-number":["AI143265"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007747","name":"University of Utah","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007747","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","ajog.org","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.ajog.2022.09.023","type":"journal-article","created":{"date-parts":[[2022,9,17]],"date-time":"2022-09-17T10:46:05Z","timestamp":1663411565000},"page":"463.e1-463.e20","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Diminished antiviral innate immune gene expression in the placenta following a maternal SARS-CoV-2 infection"],"prefix":"10.1016","volume":"228","author":[{"given":"Brahm","family":"Coler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsung-Yen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsey","family":"Carlson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Burd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeff","family":"Munson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Dacanay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orlando","family":"Cervantes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Esplin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raj P.","family":"Kapur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Feltovich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6939-7224","authenticated-orcid":false,"given":"Kristina M.","family":"Adams Waldorf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2022.09.023_bib1","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.ajog.2020.11.022","article-title":"Pregnant women with severe or critical coronavirus disease 2019 have increased composite morbidity compared with nonpregnant matched controls","volume":"224","author":"DeBolt","year":"2021","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2022.09.023_bib2","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1002\/uog.23575","article-title":"Pregnant women with SARS-CoV-2 infection are at higher risk of death and pneumonia: propensity score matched analysis of a nationwide prospective cohort (COV19Mx)","volume":"57","author":"Martinez-Portilla","year":"2021","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajog.2022.09.023_bib3","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.15585\/mmwr.mm6944e3","article-title":"Update: characteristics of symptomatic women of reproductive age with laboratory-confirmed SARS-CoV-2 infection by pregnancy status - United States, January 22-October 3, 2020","volume":"69","author":"Zambrano","year":"2020","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.ajog.2022.09.023_bib4","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.15585\/mmwr.mm6938e1","article-title":"Characteristics and maternal and birth outcomes of hospitalized pregnant women with laboratory-confirmed COVID-19 - COVID-NET, 13 states, March 1-August 22, 2020","volume":"69","author":"Delahoy","year":"2020","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.ajog.2022.09.023_bib5","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.15585\/mmwr.mm6938e2","article-title":"SARS-CoV-2 infection among hospitalized pregnant women: reasons for admission and pregnancy characteristics - eight U.S. Health care centers","volume":"69","author":"Panagiotakopoulos","year":"2020","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.ajog.2022.09.023_bib6","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.ajog.2021.05.015","article-title":"Impact of the COVID-19 pandemic on preterm birth and stillbirth: a nationwide, population-based retrospective cohort study","volume":"225","author":"Simon","year":"2021","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2022.09.023_bib7","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.15585\/mmwr.mm7047e1","article-title":"Risk for stillbirth among women with and without COVID-19 at delivery hospitalization - United States, March 2020-September 2021","volume":"70","author":"DeSisto","year":"2021","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.ajog.2022.09.023_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.micinf.2022.104949","article-title":"Clinical and genomic data of sars-cov-2 detected in maternal-fetal interface during the first wave of infection in Brazil","volume":"24","author":"Ferreira","year":"2022","journal-title":"Microbes Infect"},{"key":"10.1016\/j.ajog.2022.09.023_bib9","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1093\/jpids\/piaa153","article-title":"Severe acute respiratory syndrome coronavirus 2 placental infection and inflammation leading to fetal distress and neonatal multi-organ failure in an asymptomatic woman","volume":"10","author":"Schoenmakers","year":"2021","journal-title":"J\u00a0Pediatric Infect Dis Soc"},{"key":"10.1016\/j.ajog.2022.09.023_bib10","first-page":"75","article-title":"Higher severe acute respiratory syndrome coronavirus 2 infection rate in pregnant patients","volume":"225","author":"Lokken","year":"2021","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2022.09.023_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajogmf.2020.100145","article-title":"Vertical transmission of coronavirus disease 2019: severe acute respiratory syndrome coronavirus 2 RNA on the fetal side of the placenta in pregnancies with coronavirus disease 2019-positive mothers and neonates at birth","volume":"2","author":"Patan\u00e8","year":"2020","journal-title":"Am J Obstet Gynecol MFM"},{"key":"10.1016\/j.ajog.2022.09.023_bib12","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.placenta.2020.08.018","article-title":"A\u00a0structured review of placental morphology and histopathological lesions associated with SARS-CoV-2 infection","volume":"101","author":"Sharps","year":"2020","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2022.09.023_bib13","doi-asserted-by":"crossref","first-page":"783","DOI":"10.3389\/fcell.2020.00783","article-title":"Single-cell RNA-seq identifies cell subsets in human placenta that highly expresses factors driving pathogenesis of SARS-CoV-2","volume":"8","author":"Ashary","year":"2020","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.ajog.2022.09.023_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcv.2020.104447","article-title":"Evidence and possible mechanisms of rare maternal-fetal transmission of SARS-CoV-2","volume":"128","author":"Egloff","year":"2020","journal-title":"J\u00a0Clin Virol"},{"key":"10.1016\/j.ajog.2022.09.023_bib15","article-title":"The SARS-CoV-2 receptor ACE2 expression of maternal-fetal interface and fetal organs by single-cell transcriptome study","volume":"15","author":"Li","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.ajog.2022.09.023_bib16","first-page":"591","article-title":"Maternal respiratory SARS-CoV-2 infection in pregnancy is associated with a robust inflammatory response at the maternal-fetal interface","volume":"2","author":"Lu-Culligan","year":"2021","journal-title":"Med (N Y)"},{"key":"10.1016\/j.ajog.2022.09.023_bib17","doi-asserted-by":"crossref","first-page":"94","DOI":"10.3390\/diagnostics11010094","article-title":"The effects of COVID-19 on placenta and pregnancy: what do we know so far?","volume":"11","author":"Wong","year":"2021","journal-title":"Diagnostics (Basel)"},{"key":"10.1016\/j.ajog.2022.09.023_bib18","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1111\/1471-0528.16974","article-title":"COVID-19 and vertical transmission: assessing the expression of ACE2\/TMPRSS2 in the human fetus and placenta to assess the risk of SARS-CoV-2 infection","volume":"129","author":"Beesley","year":"2022","journal-title":"BJOG"},{"key":"10.1016\/j.ajog.2022.09.023_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajogmf.2021.100523","article-title":"Stillbirth and fetal capillary infection by SARS-CoV-2","volume":"4","author":"di Gioia","year":"2022","journal-title":"Am J Obstet Gynecol MFM"},{"key":"10.1016\/j.ajog.2022.09.023_bib20","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2020.30455","article-title":"Assessment of maternal and neonatal SARS-CoV-2 viral load, transplacental antibody transfer, and placental pathology in pregnancies during the COVID-19 pandemic","volume":"3","author":"Edlow","year":"2020","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.ajog.2022.09.023_bib21","doi-asserted-by":"crossref","DOI":"10.1128\/mSphere.00250-21","article-title":"Term human placental trophoblasts express SARS-CoV-2 entry factors ACE2, TMPRSS2, and Furin","volume":"6","author":"Ouyang","year":"2021","journal-title":"mSphere"},{"key":"10.1016\/j.ajog.2022.09.023_bib22","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.placenta.2020.08.015","article-title":"Consistent localization of SARS-CoV-2 spike glycoprotein and ACE2 over TMPRSS2 predominance in placental villi of 15 COVID-19 positive maternal-fetal dyads","volume":"100","author":"Taglauer","year":"2020","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2022.09.023_bib23","article-title":"Possible vertical transmission of corona virus disease 19 (COVID-19) from infected pregnant mothers to neonates: a multicenter study","author":"Almaghrabi","year":"2022","journal-title":"J\u00a0Matern Fetal Neonatal Med"},{"key":"10.1016\/j.ajog.2022.09.023_bib24","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1038\/s41598-019-39620-5","article-title":"Levels of systemic low-grade inflammation in pregnant mothers and their offspring are correlated","volume":"9","author":"Fink","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.ajog.2022.09.023_bib25","first-page":"77","article-title":"Disease severity, pregnancy outcomes, and maternal deaths among pregnant patients with severe acute respiratory syndrome coronavirus 2 infection in Washington State","volume":"225","author":"Lokken","year":"2021","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2022.09.023_bib26","first-page":"4","article-title":"Innate immune evasion by human respiratory RNA viruses","volume":"12","author":"Kikkert","year":"2020","journal-title":"J\u00a0Innate Immun"},{"key":"10.1016\/j.ajog.2022.09.023_bib27","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1038\/s41418-020-00633-7","article-title":"An aberrant STAT pathway is central to COVID-19","volume":"27","author":"Matsuyama","year":"2020","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.ajog.2022.09.023_bib28","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.virol.2005.09.024","article-title":"The interferon response circuit: induction and suppression by pathogenic viruses","volume":"344","author":"Haller","year":"2006","journal-title":"Virology"},{"key":"10.1016\/j.ajog.2022.09.023_bib29","doi-asserted-by":"crossref","first-page":"R277","DOI":"10.1530\/REP-16-0453","article-title":"Sterile inflammation and pregnancy complications: a review","volume":"152","author":"Nadeau-Vall\u00e9e","year":"2016","journal-title":"Reproduction"},{"key":"10.1016\/j.ajog.2022.09.023_bib30","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-93931-0","article-title":"Placental response to maternal SARS-CoV-2 infection","volume":"11","author":"Mourad","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.ajog.2022.09.023_bib31","doi-asserted-by":"crossref","first-page":"5859","DOI":"10.1038\/s41467-020-19706-9","article-title":"Immune suppression in the early stage of COVID-19 disease","volume":"11","author":"Tian","year":"2020","journal-title":"Nat Commun"},{"key":"10.1016\/j.ajog.2022.09.023_bib32","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.13091","article-title":"Molecular evidence suggesting the persistence of residual SARS-CoV-2 and immune responses in the placentas of pregnant patients recovered from COVID-19","volume":"54","author":"Wu","year":"2021","journal-title":"Cell Prolif"},{"key":"10.1016\/j.ajog.2022.09.023_bib33","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.ajog.2021.03.028","article-title":"Pregnancy alters interleukin-1 beta expression and antiviral antibody responses during severe acute respiratory syndrome coronavirus 2 infection","volume":"225","author":"Sherer","year":"2021","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2022.09.023_bib34","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.3390\/cells10071788","article-title":"MiRNA profiling in plasma and placenta of SARS-CoV-2-infected pregnant women","volume":"10","author":"Saulle","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.ajog.2022.09.023_bib35","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.3389\/fimmu.2020.01145","article-title":"Maternal immune activation alters fetal brain development and enhances proliferation of neural precursor cells in rats","volume":"11","author":"Baines","year":"2020","journal-title":"Front Immunol"},{"key":"10.1016\/j.ajog.2022.09.023_bib36","doi-asserted-by":"crossref","first-page":"230","DOI":"10.3389\/fnbeh.2018.00230","article-title":"Increasing role of maternal immune activation in neurodevelopmental disorders","volume":"12","author":"Boulanger-Bertolus","year":"2018","journal-title":"Front Behav Neurosci"},{"key":"10.1016\/j.ajog.2022.09.023_bib37","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1001\/jamapediatrics.2020.4298","article-title":"Outcomes of neonates born to mothers with severe acute respiratory syndrome coronavirus 2 infection at a large medical center in New York City","volume":"175","author":"Dumitriu","year":"2021","journal-title":"JAMA Pediatr"},{"key":"10.1016\/j.ajog.2022.09.023_bib39","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1001\/jamapsychiatry.2019.0029","article-title":"Long-term risk of neuropsychiatric disease after exposure to infection in utero","volume":"76","author":"Al-Haddad","year":"2019","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.ajog.2022.09.023_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajogmf.2021.100468","article-title":"Placental histopathology after SARS-CoV-2 infection in pregnancy: a systematic review and meta-analysis","volume":"3","author":"Di Girolamo","year":"2021","journal-title":"Am J Obstet Gynecol MFM"},{"key":"10.1016\/j.ajog.2022.09.023_bib41","article-title":"Fetal deaths in pregnancies with SARS-CoV-2 infection in Brazil: a case series","volume":"27","author":"Richtmann","year":"2020","journal-title":"Case Rep Womens Health"},{"key":"10.1016\/j.ajog.2022.09.023_bib42","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.3390\/v12111308","article-title":"Placental pathology of COVID-19 with and without fetal and neonatal infection: trophoblast necrosis and chronic histiocytic intervillositis as risk factors for transplacental transmission of SARS-CoV-2","volume":"12","author":"Schwartz","year":"2020","journal-title":"Viruses"},{"key":"10.1016\/j.ajog.2022.09.023_bib43","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1159\/000511324","article-title":"Placental pathology findings during and after SARS-CoV-2 infection: features of villitis and malperfusion","volume":"88","author":"Menter","year":"2021","journal-title":"Pathobiology"},{"key":"10.1016\/j.ajog.2022.09.023_bib44","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.placenta.2021.07.288","article-title":"Placental lesions and SARS-Cov-2 infection: diffuse placenta damage associated to poor fetal outcome","volume":"112","author":"Bouachba","year":"2021","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2022.09.023_bib45","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.placenta.2021.10.010","article-title":"Meta-analysis on COVID-19-pregnancy-related placental pathologies shows no specific pattern","volume":"117","author":"Suhren","year":"2022","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2022.09.023_bib46","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1093\/ajcp\/aqaa089","article-title":"Placental pathology in COVID-19","volume":"154","author":"Shanes","year":"2020","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.ajog.2022.09.023_bib47","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.humpath.2021.12.012","article-title":"Severe placental lesions due to maternal SARS-CoV-2 infection associated to intrauterine fetal death","volume":"121","author":"Dubucs","year":"2022","journal-title":"Hum Pathol"},{"key":"10.1016\/j.ajog.2022.09.023_bib48","doi-asserted-by":"crossref","first-page":"660","DOI":"10.5858\/arpa.2022-0029-SA","article-title":"Placental tissue destruction and insufficiency from COVID-19 causes stillbirth and neonatal death from hypoxic-ischemic injury","volume":"146","author":"Schwartz","year":"2022","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.ajog.2022.09.023_bib49","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1001\/jama.2020.2648","article-title":"Characteristics of and important lessons From the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention","volume":"323","author":"Wu","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.ajog.2022.09.023_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajogmf.2020.100118","article-title":"Coronavirus disease 2019 infection among asymptomatic and symptomatic pregnant women: two weeks of confirmed presentations to an affiliated pair of New York City hospitals","volume":"2","author":"Breslin","year":"2020","journal-title":"Am J Obstet Gynecol MFM"},{"key":"10.1016\/j.ajog.2022.09.023_bib52","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1089\/jir.2010.0101","article-title":"The ISG56\/IFIT1 gene family","volume":"31","author":"Fensterl","year":"2011","journal-title":"J\u00a0Interferon Cytokine Res"},{"key":"10.1016\/j.ajog.2022.09.023_bib53","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0065-2164(10)73004-5","article-title":"Type I interferon modulates the battle of host immune system against viruses","volume":"73","author":"Seo","year":"2010","journal-title":"Adv Appl Microbiol"},{"key":"10.1016\/j.ajog.2022.09.023_bib54","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.765730","article-title":"The new old CD8+ T cells in the immune paradox of pregnancy","volume":"12","author":"Hardardottir","year":"2021","journal-title":"Front Immunol"},{"key":"10.1016\/j.ajog.2022.09.023_bib55","article-title":"Exhausted and senescent T cells at the maternal-fetal interface in preterm and term labor","volume":"2019","author":"Slutsky","year":"2019","journal-title":"J\u00a0Immunol Res"},{"key":"10.1016\/j.ajog.2022.09.023_bib56","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/j.1600-0897.2010.00908.x","article-title":"Placental viral infection sensitizes to endotoxin-induced pre-term labor: a double hit hypothesis","volume":"65","author":"Cardenas","year":"2011","journal-title":"Am J Reprod Immunol"},{"key":"10.1016\/j.ajog.2022.09.023_bib57","doi-asserted-by":"crossref","first-page":"934","DOI":"10.4049\/jimmunol.1300661","article-title":"Viral infection of the pregnant cervix predisposes to ascending bacterial infection","volume":"191","author":"Racicot","year":"2013","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.ajog.2022.09.023_bib58","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.5858\/arpa.2021-0246-SA","article-title":"Defining severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) placentitis","volume":"145","author":"Watkins","year":"2021","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.ajog.2022.09.023_bib59","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1097\/PAS.0000000000001889","article-title":"Diffuse and localized SARS-CoV-2 placentitis: prevalence and pathogenesis of an uncommon complication of COVID-19 infection during pregnancy","volume":"46","author":"Redline","year":"2022","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.ajog.2022.09.023_bib60","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.58716","article-title":"Does the human placenta express the canonical cell entry mediators for SARS-CoV-2?","volume":"9","author":"Pique-Regi","year":"2020","journal-title":"Elife"},{"key":"10.1016\/j.ajog.2022.09.023_bib61","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.cell.2020.12.027","article-title":"Compromised SARS-CoV-2-specific placental antibody transfer","volume":"184","author":"Atyeo","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.ajog.2022.09.023_bib62","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.abi7428","article-title":"Maternal SARS-CoV-2 infection elicits sexually dimorphic placental immune responses","volume":"13","author":"Bordt","year":"2021","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.ajog.2022.09.023_bib63","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.110938","article-title":"Single-cell RNA sequencing reveals immunological rewiring at the maternal-fetal interface following asymptomatic\/mild SARS-CoV-2 infection","volume":"39","author":"Sureshchandra","year":"2022","journal-title":"Cell Rep"},{"key":"10.1016\/j.ajog.2022.09.023_bib64","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.74153","article-title":"Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences","volume":"11","author":"Lee","year":"2022","journal-title":"Elife"},{"key":"10.1016\/j.ajog.2022.09.023_bib65","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1001\/jama.2022.1190","article-title":"Association of SARS-CoV-2 infection with serious maternal morbidity and mortality from obstetric complications","volume":"327","author":"Metz","year":"2022","journal-title":"JAMA"},{"key":"10.1016\/j.ajog.2022.09.023_bib66","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.15585\/mmwr.mm6944e2","article-title":"Birth and infant outcomes following laboratory-confirmed SARS-CoV-2 infection in pregnancy - SET-NET, 16 jurisdictions, March 29-October 14, 2020","volume":"69","author":"Woodworth","year":"2020","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.ajog.2022.09.023_bib67","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S2352-4642(20)30342-4","article-title":"Characteristics and outcomes of neonatal SARS-CoV-2 infection in the UK: a prospective national cohort study using active surveillance","volume":"5","author":"Gale","year":"2021","journal-title":"Lancet Child Adolesc Health"},{"key":"10.1016\/j.ajog.2022.09.023_bib68","doi-asserted-by":"crossref","first-page":"m2107","DOI":"10.1136\/bmj.m2107","article-title":"Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study","volume":"369","author":"Knight","year":"2020","journal-title":"BMJ"},{"key":"10.1016\/j.ajog.2022.09.023_bib69","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/j.ajog.2020.05.031","article-title":"Clinical characteristics of 46 pregnant women with a severe acute respiratory syndrome coronavirus 2 infection in Washington State","volume":"223","author":"Lokken","year":"2020","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2022.09.023_bib70","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1038\/s41582-021-00530-8","article-title":"Maternal immune activation and neuroinflammation in human neurodevelopmental disorders","volume":"17","author":"Han","year":"2021","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.ajog.2022.09.023_bib71","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.ajog.2019.06.013","article-title":"The fetal origins of mental illness","volume":"221","author":"Al-Haddad","year":"2019","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2022.09.023_bib72","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1001\/archpsyc.1988.01800260109013","article-title":"Adult schizophrenia following prenatal exposure to an influenza epidemic","volume":"45","author":"Mednick","year":"1988","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.ajog.2022.09.023_bib73","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.euroneuro.2008.06.001","article-title":"Dopamine and serotonin levels following prenatal viral infection in mouse--implications for psychiatric disorders such as schizophrenia and autism","volume":"18","author":"Winter","year":"2008","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.ajog.2022.09.023_bib74","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1176\/appi.ajp.2008.08010089","article-title":"Prenatal exposure to maternal infection and executive dysfunction in adult schizophrenia","volume":"166","author":"Brown","year":"2009","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.ajog.2022.09.023_bib75","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.bbi.2008.07.012","article-title":"Activation of the maternal immune system alters cerebellar development in the offspring","volume":"23","author":"Shi","year":"2009","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.ajog.2022.09.023_bib76","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1001\/archpsyc.1997.01830160040006","article-title":"Adult major affective disorder after prenatal exposure to an influenza epidemic","volume":"54","author":"Mach\u00f3n","year":"1997","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.ajog.2022.09.023_bib77","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0920-9964(01)00346-2","article-title":"Adult schizotypal personality characteristics and prenatal influenza in a Finnish birth cohort","volume":"54","author":"Mach\u00f3n","year":"2002","journal-title":"Schizophr Res"},{"key":"10.1016\/j.ajog.2022.09.023_bib78","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1001\/archpsyc.1990.01810210077012","article-title":"Exposure to influenza epidemics during gestation and adult schizophrenia. A 40-year study","volume":"47","author":"Barr","year":"1990","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.ajog.2022.09.023_bib79","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1159\/000491821","article-title":"Intracellular pathogen infections and immune response in autism","volume":"25","author":"Abib","year":"2018","journal-title":"Neuroimmunomodulation"},{"key":"10.1016\/j.ajog.2022.09.023_bib80","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1146\/annurev-publhealth-031816-044318","article-title":"The changing epidemiology of autism spectrum disorders","volume":"38","author":"Lyall","year":"2017","journal-title":"Annu Rev Public Health"},{"key":"10.1016\/j.ajog.2022.09.023_bib81","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.bbi.2016.06.005","article-title":"Maternal infection during pregnancy and risk of autism spectrum disorders: a systematic review and meta-analysis","volume":"58","author":"Jiang","year":"2016","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.ajog.2022.09.023_bib82","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1038\/mp.2017.119","article-title":"Prenatal fever and autism risk","volume":"23","author":"Hornig","year":"2018","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.ajog.2022.09.023_bib83","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/j.tim.2018.05.011","article-title":"The aftermath of Zika: need for long-term monitoring of exposed children","volume":"26","author":"Adams Waldorf","year":"2018","journal-title":"Trends Microbiol"},{"key":"10.1016\/j.ajog.2022.09.023_bib84","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1001\/jamapediatrics.2019.5204","article-title":"Neurodevelopmental abnormalities in children with in utero Zika virus exposure without congenital Zika syndrome","volume":"174","author":"Mulkey","year":"2020","journal-title":"JAMA Pediatr"},{"key":"10.1016\/j.ajog.2022.09.023_bib85","doi-asserted-by":"crossref","first-page":"e146","DOI":"10.1093\/cid\/ciaa1833","article-title":"Neurodevelopmental outcomes of children following in utero exposure to Zika in Nicaragua","volume":"72","author":"Stringer","year":"2021","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ajog.2022.09.023_bib86","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1186\/s12887-020-02331-2","article-title":"Pediatric neurodevelopment by prenatal Zika virus exposure: a cross-sectional study of the Microcephaly Epidemic Research Group Cohort","volume":"20","author":"Sobral da Silva","year":"2020","journal-title":"BMC Pediatr"},{"key":"10.1016\/j.ajog.2022.09.023_bib87","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.placenta.2022.03.003","article-title":"Low-level SARS-CoV-2 viremia coincident with COVID placentitis and stillbirth","volume":"121","author":"Mithal","year":"2022","journal-title":"Placenta"},{"key":"10.1016\/j.ajog.2022.09.023_bib88","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajogmf.2020.100133","article-title":"Detection of severe acute respiratory syndrome coronavirus 2 in placental and fetal membrane samples","volume":"2","author":"Penfield","year":"2020","journal-title":"Am J Obstet Gynecol MFM"},{"key":"10.1016\/j.ajog.2022.09.023_bib89","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.3390\/v13081670","article-title":"Unique severe COVID-19 placental signature independent of severity of clinical maternal symptoms","volume":"13","author":"Husen","year":"2021","journal-title":"Viruses"},{"key":"10.1016\/j.ajog.2022.09.023_bib90","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1038\/s41467-021-27745-z","article-title":"Maternal-fetal immune responses in pregnant women infected with SARS-CoV-2","volume":"13","author":"Garcia-Flores","year":"2022","journal-title":"Nat Commun"},{"key":"10.1016\/j.ajog.2022.09.023_bib91","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.743022","article-title":"The effects of COVID-19 on the placenta during pregnancy","volume":"12","author":"Rad","year":"2021","journal-title":"Front Immunol"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937822007475?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937822007475?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T01:35:46Z","timestamp":1715218546000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937822007475"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":89,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["S0002937822007475"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2022.09.023","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Diminished antiviral innate immune gene expression in the placenta following a maternal SARS-CoV-2 infection","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2022.09.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}