{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T18:15:09Z","timestamp":1790273709069,"version":"4.1.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T00:00:00Z","timestamp":1724457600000},"content-version":"am","delay-in-days":358,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100029613","name":"American Association of Obstetricians and Gynecologists Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100029613","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01 AG047290"],"award-info":[{"award-number":["R01 AG047290"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.ajog.2023.05.023","type":"journal-article","created":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T12:02:47Z","timestamp":1685016167000},"page":"309.e1-309.e10","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Effects of preoperative intravaginal estrogen on pelvic floor disorder symptoms in postmenopausal women with pelvic organ prolapse"],"prefix":"10.1016","volume":"229","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4775-2368","authenticated-orcid":false,"given":"David D.","family":"Rahn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holly E.","family":"Richter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivian W.","family":"Sung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda S.","family":"Hynan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica E.","family":"Pruszynski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2023.05.023_bib1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s00192-014-2464-0","article-title":"Assessment of vaginal atrophy: a review","volume":"26","author":"Weber","year":"2015","journal-title":"Int Urogynecol J"},{"issue":"Suppl","key":"10.1016\/j.ajog.2023.05.023_bib2","doi-asserted-by":"crossref","first-page":"S17","DOI":"10.1016\/0378-5122(95)00958-2","article-title":"The prevalence of urogenital symptoms in postmenopausal women","volume":"22","author":"Stenberg","year":"1995","journal-title":"Maturitas"},{"key":"10.1016\/j.ajog.2023.05.023_bib3","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1097\/AOG.0000000000000526","article-title":"Vaginal estrogen for genitourinary syndrome of menopause: a systematic review","volume":"124","author":"Rahn","year":"2014","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2023.05.023_bib4","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00192-014-2554-z","article-title":"Vaginal estrogen use in postmenopausal women with pelvic floor disorders: systematic review and practice guidelines","volume":"26","author":"Rahn","year":"2015","journal-title":"Int Urogynecol J"},{"key":"10.1016\/j.ajog.2023.05.023_bib5","first-page":"CD001405","article-title":"Oestrogen therapy for urinary incontinence in post-menopausal women","volume":"10","author":"Cody","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ajog.2023.05.023_bib6","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.fertnstert.2005.06.042","article-title":"A\u00a0randomized comparative study of the effects of oral and topical estrogen therapy on the lower urinary tract of hysterectomized postmenopausal women","volume":"85","author":"Long","year":"2006","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ajog.2023.05.023_bib7","doi-asserted-by":"crossref","first-page":"e227","DOI":"10.1097\/SPV.0000000000000899","article-title":"Design of a randomized clinical trial of perioperative vaginal estrogen versus placebo with transvaginal native tissue apical prolapse repair (Investigation to Minimize Prolapse Recurrence Of the Vagina using Estrogen: IMPROVE)","volume":"27","author":"Rahn","year":"2021","journal-title":"Female Pelvic Med Reconstr Surg"},{"key":"10.1016\/j.ajog.2023.05.023_bib8","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1447-0756.2001.tb01266.x","article-title":"The effect of estradiol vaginal tablet and conjugated estrogen cream on urogenital symptoms in postmenopausal women: a comparative study","volume":"27","author":"Manonai","year":"2001","journal-title":"J\u00a0Obstet Gynaecol Res"},{"key":"10.1016\/j.ajog.2023.05.023_bib9","doi-asserted-by":"crossref","first-page":"3728","DOI":"10.1210\/jc.2014-1216","article-title":"Effects of preoperative local estrogen in postmenopausal women with prolapse: a randomized trial","volume":"99","author":"Rahn","year":"2014","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.ajog.2023.05.023_bib10","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.ajog.2004.12.025","article-title":"Short forms of two condition-specific quality-of-life questionnaires for women with pelvic floor disorders (PFDI-20 and PFIQ-7)","volume":"193","author":"Barber","year":"2005","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2023.05.023_bib11","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1007\/s00192-012-2020-8","article-title":"A\u00a0new measure of sexual function in women with pelvic floor disorders (PFD): the Pelvic Organ prolapse\/Incontinence Sexual Questionnaire, IUGA-revised (PISQ-IR)","volume":"24","author":"Rogers","year":"2013","journal-title":"Int Urogynecol J"},{"key":"10.1016\/j.ajog.2023.05.023_bib12","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1097\/gme.0b013e3181a48c4e","article-title":"Efficacy and safety of low-dose regimens of conjugated estrogens cream administered vaginally","volume":"16","author":"Bachmann","year":"2009","journal-title":"Menopause"},{"key":"10.1016\/j.ajog.2023.05.023_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0136265","article-title":"Local oestrogen for pelvic floor disorders: a systematic review","volume":"10","author":"Weber","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.ajog.2023.05.023_bib14","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1097\/gme.0b013e3182104977","article-title":"Randomized trial of estradiol vaginal ring versus oral oxybutynin for the treatment of overactive bladder","volume":"18","author":"Nelken","year":"2011","journal-title":"Menopause"},{"key":"10.1016\/j.ajog.2023.05.023_bib15","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.eururo.2008.06.051","article-title":"Is there a synergistic effect of topical oestrogens when administered with antimuscarinics in the treatment of symptomatic detrusor overactivity?","volume":"55","author":"Serati","year":"2009","journal-title":"Eur Urol"},{"key":"10.1016\/j.ajog.2023.05.023_bib16","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/nau.20583","article-title":"Randomized comparison of tolterodine with vaginal estrogen cream versus tolterodine alone for the treatment of postmenopausal women with overactive bladder syndrome","volume":"28","author":"Tseng","year":"2009","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.ajog.2023.05.023_bib17","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.maturitas.2008.07.015","article-title":"Estrogen therapy influence on periurethral vessels in postmenopausal incontinent women using Doppler velocimetry analysis","volume":"61","author":"Kobata","year":"2008","journal-title":"Maturitas"},{"key":"10.1016\/j.ajog.2023.05.023_bib18","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1097\/SPV.0000000000000256","article-title":"Combined tolterodine and vaginal estradiol cream for overactive bladder symptoms after randomized single-therapy treatment","volume":"22","author":"Ellington","year":"2016","journal-title":"Female Pelvic Med Reconstr Surg"},{"key":"10.1016\/j.ajog.2023.05.023_bib19","doi-asserted-by":"crossref","first-page":"e227","DOI":"10.1097\/SPV.0000000000000899","article-title":"Design of a randomized clinical trial of perioperative vaginal estrogen versus placebo with transvaginal native tissue apical prolapse repair (Investigation to Minimize Prolapse Recurrence of the Vagina using Estrogen: IMPROVE)","volume":"27","author":"Rahn","year":"2021","journal-title":"Female Pelvic Med Reconstr Surg"},{"key":"10.1016\/j.ajog.2023.05.023_bib20","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/s12955-021-01721-z","article-title":"Identification of the urogenital Distress Inventory-6 and the Incontinence Impact Questionnaire-7 cutoff scores in urinary incontinent women","volume":"19","author":"Skorupska","year":"2021","journal-title":"Health Qual Life Outcomes"},{"key":"10.1016\/j.ajog.2023.05.023_bib21","first-page":"99","article-title":"Genitourinary syndrome of menopause assessment tools","volume":"12","author":"Mension","year":"2021","journal-title":"J\u00a0Midlife Health"},{"key":"10.1016\/j.ajog.2023.05.023_bib22","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.maturitas.2017.03.315","article-title":"Relationship between changes in vulvar-vaginal atrophy and changes in sexual functioning","volume":"100","author":"Pinkerton","year":"2017","journal-title":"Maturitas"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937823003526?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937823003526?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:37:25Z","timestamp":1762079845000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937823003526"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["S0002937823003526"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2023.05.023","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of preoperative intravaginal estrogen on pelvic floor disorder symptoms in postmenopausal women with pelvic organ prolapse","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2023.05.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}