{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T00:28:27Z","timestamp":1793320107029,"version":"4.5.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:00:00Z","timestamp":1771545600000},"content-version":"am","delay-in-days":356,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["HL 071944"],"award-info":[{"award-number":["HL 071944"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","ajog.org","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.ajog.2024.05.031","type":"journal-article","created":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T03:08:23Z","timestamp":1716433703000},"page":"314.e1-314.e12","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Prepregnancy physiology and subsequent preterm preeclampsia"],"prefix":"10.1016","volume":"232","author":[{"given":"Ira M.","family":"Bernstein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary J.","family":"Badger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole A.","family":"McBride","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajog.2024.05.031_bib1","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1161\/HYPERTENSIONAHA.110.150078","article-title":"Preeclampsia and cardiovascular disease death: prospective evidence from the child health and development studies cohort","volume":"56","author":"Mongraw-Chaffin","year":"2010","journal-title":"Hypertension"},{"key":"10.1016\/j.ajog.2024.05.031_bib2","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s11906-015-0595-4","article-title":"Preeclampsia: syndrome or disease?","volume":"17","author":"Myatt","year":"2015","journal-title":"Curr Hypertens Rep"},{"key":"10.1016\/j.ajog.2024.05.031_bib3","doi-asserted-by":"crossref","first-page":"622","DOI":"10.3109\/14767050903258746","article-title":"Evidence for distinct preterm and term phenotypes of preeclampsia","volume":"23","author":"Phillips","year":"2010","journal-title":"J\u00a0Matern Fetal Neonatal Med"},{"key":"10.1016\/j.ajog.2024.05.031_bib4","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1161\/HYPERTENSIONAHA.108.117358","article-title":"Early and late preeclampsia: two different maternal hemodynamic states in the latent phase of the disease","volume":"52","author":"Valensise","year":"2008","journal-title":"Hypertension"},{"key":"10.1016\/j.ajog.2024.05.031_bib5","first-page":"306","article-title":"Intolerance to volume expansion: a theorized mechanism for the development of preeclampsia","volume":"92","author":"Bernstein","year":"1998","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2024.05.031_bib6","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1038\/s41572-023-00417-6","article-title":"Pre-eclampsia","volume":"9","author":"Dimitriadis","year":"2023","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.ajog.2024.05.031_bib7","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1111\/1471-0528.17370","article-title":"Preterm and term pre-eclampsia: relative burdens of maternal and perinatal complications","volume":"130","author":"von Dadelszen","year":"2023","journal-title":"BJOG"},{"key":"10.1016\/j.ajog.2024.05.031_bib8","doi-asserted-by":"crossref","first-page":"2198","DOI":"10.3109\/14767058.2012.684110","article-title":"Preterm preeclampsia: 32 to 37 weeks gestation","volume":"25","author":"Jelin","year":"2012","journal-title":"J\u00a0Matern Fetal Neonatal Med"},{"key":"10.1016\/j.ajog.2024.05.031_bib9","doi-asserted-by":"crossref","first-page":"772","DOI":"10.3109\/00016349509021195","article-title":"Death rates from ischemic heart disease in women with a history of hypertension in pregnancy","volume":"74","author":"J\u00f3nsd\u00f3ttir","year":"1995","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.ajog.2024.05.031_bib10","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1177\/1933719109338876","article-title":"The relationship of plasma volume, sympathetic tone, and proinflammatory cytokines in young healthy nonpregnant women","volume":"16","author":"Bernstein","year":"2009","journal-title":"Reprod Sci"},{"key":"10.1016\/j.ajog.2024.05.031_bib11","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1097\/01.AOG.0000124805.04957.05","article-title":"Platelet activation, sympathetic tone, and plasma volume in nulligravid women of reproductive age","volume":"103","author":"Damron","year":"2004","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2024.05.031_bib12","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.preghy.2013.01.006","article-title":"Prepregnancy vascular dysfunction in women who subsequently develop hypertension during pregnancy","volume":"3","author":"Hale","year":"2013","journal-title":"Pregnancy Hypertens"},{"key":"10.1016\/j.ajog.2024.05.031_bib13","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2023.1055223","article-title":"Association between android fat mass, gynoid fat mass and cardiovascular and all-cause mortality in adults: NHANES 2003-2007","volume":"10","author":"Ma","year":"2023","journal-title":"Front Cardiovasc Med"},{"key":"10.1016\/j.ajog.2024.05.031_bib14","doi-asserted-by":"crossref","first-page":"4360","DOI":"10.1210\/jc.2008-0804","article-title":"Abdominal and gynoid fat mass are associated with cardiovascular risk factors in men and women","volume":"93","author":"Wiklund","year":"2008","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.ajog.2024.05.031_bib15","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"A\u00a0new equation to estimate glomerular filtration\u00a0rate","volume":"150","author":"Levey","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ajog.2024.05.031_bib16","first-page":"620","article-title":"Uterine artery hemodynamic adaptations through the menstrual cycle into early pregnancy","volume":"99","author":"Bernstein","year":"2002","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2024.05.031_bib17","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1097\/01.AOG.0000152346.45920.45","article-title":"The influence of pregnancy on arterial compliance","volume":"105","author":"Bernstein","year":"2005","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2024.05.031_bib18","first-page":"171","article-title":"Angiotensinogen genotype and plasma volume in nulligravid women","volume":"92","author":"Bernstein","year":"1998","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2024.05.031_bib19","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1161\/01.CIR.70.3.425","article-title":"Pulsed Doppler echocardiographic determination of stroke volume and cardiac output: clinical validation of two new methods using the apical window","volume":"70","author":"Lewis","year":"1984","journal-title":"Circulation"},{"key":"10.1016\/j.ajog.2024.05.031_bib20","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.preghy.2016.07.001","article-title":"Differences in cardiovascular function comparing prior preeclamptics with nulliparous controls","volume":"6","author":"Bernstein","year":"2016","journal-title":"Pregnancy Hypertens"},{"key":"10.1016\/j.ajog.2024.05.031_bib21","doi-asserted-by":"crossref","first-page":"633.e1","DOI":"10.1016\/j.ajog.2015.01.005","article-title":"Pregnancy induces persistent changes in vascular compliance in primiparous women","volume":"212","author":"Morris","year":"2015","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajog.2024.05.031_bib22","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1097\/00004691-199811000-00013","article-title":"Normative data on phases of the Valsalva maneuver","volume":"15","author":"Denq","year":"1998","journal-title":"J\u00a0Clin Neurophysiol"},{"key":"10.1016\/j.ajog.2024.05.031_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF02291382","article-title":"Mechanisms of blood pressure alterations in response to the Valsalva maneuver in postural tachycardia syndrome","volume":"10","author":"Sandroni","year":"2000","journal-title":"Clin Auton Res"},{"key":"10.1016\/j.ajog.2024.05.031_bib24","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J\u00a0Biomed Inform"},{"key":"10.1016\/j.ajog.2024.05.031_bib25","series-title":"Chesley's hypertensive disorders in pregnancy [internet]","first-page":"71","article-title":"Preconceptional, nutritional and periconceptional pathways to preeclampsia","author":"Conrad","year":"2015"},{"key":"10.1016\/j.ajog.2024.05.031_bib26","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1093\/humrep\/17.6.1649","article-title":"Paternal age and maternal age are risk factors for miscarriage; results of a multicentre European study","volume":"17","author":"de la Rochebrochard","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ajog.2024.05.031_bib27","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/uog.20126","article-title":"Metabolic syndrome and pre-eclampsia","volume":"54","author":"Hooijschuur","year":"2019","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajog.2024.05.031_bib28","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1111\/1471-0528.12189","article-title":"Metabolic syndrome and the risk for recurrent pre-eclampsia: a retrospective cohort study","volume":"120","author":"Stekkinger","year":"2013","journal-title":"BJOG"},{"key":"10.1016\/j.ajog.2024.05.031_bib29","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1136\/bmj.39335.385301.BE","article-title":"Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis","volume":"335","author":"Bellamy","year":"2007","journal-title":"BMJ"},{"key":"10.1016\/j.ajog.2024.05.031_bib30","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1016\/S0140-6736(05)67726-4","article-title":"Cardiovascular health after maternal placental syndromes (CHAMPS): population-based retrospective cohort study","volume":"366","author":"Ray","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.ajog.2024.05.031_bib31","doi-asserted-by":"crossref","first-page":"6239","DOI":"10.1210\/jc.2004-0548","article-title":"Preeclampsia and future cardiovascular disease: potential role of altered angiogenesis and insulin resistance","volume":"89","author":"Wolf","year":"2004","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.ajog.2024.05.031_bib32","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1136\/heartjnl-2018-313453","article-title":"Future risk of cardiovascular disease risk factors and events in women after a hypertensive disorder of pregnancy","volume":"105","author":"Benschop","year":"2019","journal-title":"Heart"},{"key":"10.1016\/j.ajog.2024.05.031_bib33","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1016\/j.jacc.2020.03.028","article-title":"Incidence and long-term outcomes of hypertensive disorders of pregnancy","volume":"75","author":"Garovic","year":"2020","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.ajog.2024.05.031_bib34","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1111\/ppe.12388","article-title":"Hypertensive disorders in pregnancy and the risk of subsequent cardiovascular disease","volume":"31","author":"Grandi","year":"2017","journal-title":"Paediatr Perinat Epidemiol"},{"key":"10.1016\/j.ajog.2024.05.031_bib35","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1016\/j.jacc.2020.01.064","article-title":"Women's cardiovascular health after hypertensive pregnancy: the long view from labor and delivery becomes clearer","volume":"75","author":"Honigberg","year":"2020","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.ajog.2024.05.031_bib36","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1093\/eurheartj\/ehaa1044","article-title":"Cardiovascular health after menopause transition, pregnancy disorders, and other gynaecologic conditions: a consensus document from European cardiologists, gynaecologists, and endocrinologists","volume":"42","author":"Maas","year":"2021","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ajog.2024.05.031_bib37","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1093\/eurheartj\/ehy863","article-title":"Does pregnancy complication history improve cardiovascular disease risk prediction? Findings from the HUNT study in Norway","volume":"40","author":"Markovitz","year":"2019","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ajog.2024.05.031_bib38","article-title":"Hypertensive disorders of pregnancy and future maternal cardiovascular risk","volume":"7","author":"Ying","year":"2018","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.ajog.2024.05.031_bib39","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1159\/000367627","article-title":"Preeclampsia and maternal cardiovascular disease: consequence or predisposition?","volume":"51","author":"Osol","year":"2014","journal-title":"J\u00a0Vasc Res"},{"key":"10.1016\/j.ajog.2024.05.031_bib40","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1097\/00001703-200312000-00002","article-title":"Pregnancy: a stress test for life","volume":"15","author":"Williams","year":"2003","journal-title":"Curr Opin Obstet Gynecol"},{"key":"10.1016\/j.ajog.2024.05.031_bib41","first-page":"303","article-title":"The familial factor in toxemia of pregnancy","volume":"32","author":"Chesley","year":"1968","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2024.05.031_bib42","first-page":"1","article-title":"Preterm preeclampsia risk modelling: examining hemodynamic, biochemical, and biophysical markers prior to pregnancy","volume":"2023","author":"Loftness","year":"2023","journal-title":"Ann Int Conf IEEE Eng Med Biol Soc."},{"key":"10.1016\/j.ajog.2024.05.031_bib43","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1177\/1933719117725815","article-title":"Effect of pregnancy interval on second pregnancy blood pressure following prior preeclampsia","volume":"25","author":"Howe","year":"2018","journal-title":"Reprod Sci"},{"key":"10.1016\/j.ajog.2024.05.031_bib44","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1055\/s-2007-1016248","article-title":"Endothelial dysfunction in preeclampsia","volume":"16","author":"Roberts","year":"1998","journal-title":"Semin Reprod Endocrinol"},{"key":"10.1016\/j.ajog.2024.05.031_bib45","doi-asserted-by":"crossref","first-page":"R1062","DOI":"10.1152\/ajpregu.00204.2018","article-title":"Residual vascular dysfunction in women with a history of preeclampsia","volume":"315","author":"Stanhewicz","year":"2018","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.ajog.2024.05.031_bib46","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1038\/hr.2016.152","article-title":"Pathophysiology of preeclampsia: an angiogenic imbalance and long-lasting systemic vascular dysfunction","volume":"40","author":"Tomimatsu","year":"2017","journal-title":"Hypertens Res"},{"key":"10.1016\/j.ajog.2024.05.031_bib47","first-page":"1122","article-title":"Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists\u2019 Task Force on Hypertension in Pregnancy","volume":"122","year":"2013","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajog.2024.05.031_bib48","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.jsgi.2005.11.006","article-title":"Agonistic antibodies directed at the angiotensin II, AT1 receptor in preeclampsia","volume":"13","author":"Dechend","year":"2006","journal-title":"J\u00a0Soc Gynecol Investig"},{"key":"10.1016\/j.ajog.2024.05.031_bib49","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1172\/JCI107462","article-title":"A\u00a0study of angiotensin II pressor response throughout primigravid pregnancy","volume":"52","author":"Gant","year":"1973","journal-title":"J\u00a0Clin Invest"}],"container-title":["American Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937824006136?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002937824006136?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T17:21:46Z","timestamp":1740072106000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002937824006136"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":49,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S0002937824006136"],"URL":"https:\/\/doi.org\/10.1016\/j.ajog.2024.05.031","relation":{},"ISSN":["0002-9378"],"issn-type":[{"value":"0002-9378","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prepregnancy physiology and subsequent preterm preeclampsia","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajog.2024.05.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}