{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T06:47:43Z","timestamp":1793170063023,"version":"4.5.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajogmfm.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics & Gynecology MFM"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.ajogmf.2020.100219","type":"journal-article","created":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T12:40:14Z","timestamp":1599050414000},"page":"100219","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Pregnancy duration with use of 17-\u03b1-hydroxyprogesterone caproate in a retrospective cohort at high risk of recurrent preterm birth"],"prefix":"10.1016","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9199-2134","authenticated-orcid":false,"given":"Katherine","family":"Massa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Childress","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura K.","family":"Vricella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"Boerrigter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Briana H.K.","family":"Franklin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Sauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raina","family":"Armbruster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy","family":"Tomlinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajogmf.2020.100219_bib1","doi-asserted-by":"crossref","first-page":"3027","DOI":"10.1016\/S0140-6736(16)31593-8","article-title":"Global, regional, and national causes of under-5 mortality in 2000-15: an updated systematic analysis with implications for the sustainable development goals","volume":"388","author":"Liu","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.ajogmf.2020.100219_bib2","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.clp.2017.01.003","article-title":"Long-term impact of preterm birth: neurodevelopmental and physical health outcomes","volume":"44","author":"Luu","year":"2017","journal-title":"Clin Perinatol"},{"key":"10.1016\/j.ajogmf.2020.100219_bib3","doi-asserted-by":"crossref","first-page":"103.e1","DOI":"10.1016\/j.ajog.2016.01.004","article-title":"Preterm neonatal morbidity and mortality by gestational age: a contemporary cohort","volume":"215","author":"Manuck","year":"2016","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2020.100219_bib4","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1080\/14767058.2016.1220521","article-title":"Universal cervical length screening for preterm birth prevention in the United States","volume":"30","author":"Khalifeh","year":"2017","journal-title":"J\u00a0Matern Fetal Neonatal Med"},{"key":"10.1016\/j.ajogmf.2020.100219_bib5","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1007\/s00404-017-4619-y","article-title":"Screening and treatment for short cervical length in pregnancy: a physician survey in the United States","volume":"297","author":"Martell","year":"2018","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.ajogmf.2020.100219_bib7","first-page":"1","article-title":"Births: final data for 2018","volume":"68","author":"Martin","year":"2019","journal-title":"Natl Vital Stat Rep"},{"key":"10.1016\/j.ajogmf.2020.100219_bib8","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1067\/mob.2003.41","article-title":"Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterm birth in women at increased risk: a randomized placebo-controlled double-blind study","volume":"188","author":"da Fonseca","year":"2003","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2020.100219_bib9","doi-asserted-by":"crossref","first-page":"375.e1","DOI":"10.1016\/j.ajog.2009.08.015","article-title":"Multicenter randomized trial of cerclage for preterm birth prevention in high-risk women with shortened midtrimester cervical length","volume":"201","author":"Owen","year":"2009","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2020.100219_bib10","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.1056\/NEJMoa035140","article-title":"Prevention of recurrent preterm delivery by 17 alpha-hydroxyprogesterone caproate","volume":"348","author":"Meis","year":"2003","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ajogmf.2020.100219_bib11","first-page":"963","article-title":"ACOG Committee Opinion number 419 October 2008 (replaces no. 291, November 2003). Use of progesterone to reduce preterm birth","volume":"112","year":"2008","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2020.100219_bib12","doi-asserted-by":"crossref","first-page":"B11","DOI":"10.1016\/j.ajog.2017.01.022","article-title":"The choice of progestogen for the prevention of preterm birth in women with singleton pregnancy and prior preterm birth","volume":"216","year":"2017","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2020.100219_bib13","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1055\/s-0039-3400227","article-title":"17-OHPC to prevent recurrent preterm birth in singleton gestations (PROLONG study): a multicenter, international, randomized double-blind trial","volume":"37","author":"Blackwell","year":"2020","journal-title":"Am J Perinatol"},{"key":"10.1016\/j.ajogmf.2020.100219_bib14","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1111\/j.1471-0528.2011.03045.x","article-title":"Perinatal morbidity associated with late preterm deliveries compared with deliveries between 37 and 40 weeks of gestation","volume":"118","author":"Cheng","year":"2011","journal-title":"BJOG"},{"key":"10.1016\/j.ajogmf.2020.100219_bib15","doi-asserted-by":"crossref","first-page":"622.e1","DOI":"10.1016\/j.ajog.2016.07.013","article-title":"Nonresponse to 17-alpha hydroxyprogesterone caproate for recurrent spontaneous preterm birth prevention: clinical prediction and generation of a risk scoring system","volume":"215","author":"Manuck","year":"2016","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2020.100219_bib16","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1093\/ije\/dyq195","article-title":"Maternal underweight and the risk of preterm birth and low birth weight: a systematic review and meta-analyses","volume":"40","author":"Han","year":"2011","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.ajogmf.2020.100219_bib17","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1001\/jama.2017.3635","article-title":"Association of gestational weight gain with maternal and infant outcomes: a systematic review and meta-analysis","volume":"317","author":"Goldstein","year":"2017","journal-title":"JAMA"},{"key":"10.1016\/j.ajogmf.2020.100219_bib18","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0140-6736(08)60074-4","article-title":"Epidemiology and causes of preterm birth","volume":"371","author":"Goldenberg","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.ajogmf.2020.100219_bib19","doi-asserted-by":"crossref","first-page":"2762","DOI":"10.1093\/humrep\/17.10.2762","article-title":"Fetal sex and preterm birth: are males at greater risk?","volume":"17","author":"Zeitlin","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ajogmf.2020.100219_bib20","doi-asserted-by":"crossref","first-page":"576.e1","DOI":"10.1016\/j.ajog.2007.01.039","article-title":"Recurrence risk for preterm delivery","volume":"196","author":"McManemy","year":"2007","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2020.100219_bib21","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/ijgo.12940","article-title":"A\u00a0systematic review and meta-analysis of randomized controlled trials comparing 17-alpha-hydroxyprogesterone caproate versus placebo for the prevention of recurrent preterm birth","volume":"147","author":"Fernandez-Macias","year":"2019","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.ajogmf.2020.100219_bib22","doi-asserted-by":"crossref","first-page":"351.e1","DOI":"10.1016\/j.ajog.2010.02.019","article-title":"17-alpha-hydroxyprogesterone caproate for the prevention of preterm birth in women with prior preterm birth and a short cervical length","volume":"202","author":"Berghella","year":"2010","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2020.100219_bib23","doi-asserted-by":"crossref","first-page":"600.e1","DOI":"10.1016\/j.ajog.2017.02.025","article-title":"17-alpha hydroxyprogesterone caproate did not reduce the rate of recurrent preterm birth in a prospective cohort study","volume":"216","author":"Nelson","year":"2017","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2020.100219_bib24","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jri.2014.03.008","article-title":"The effect of progesterone on genes involved in preterm labor","volume":"104\u2013105","author":"Okabe","year":"2014","journal-title":"J\u00a0Reprod Immunol"},{"key":"10.1016\/j.ajogmf.2020.100219_bib25","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.jsgi.2003.12.004","article-title":"Myometrial progesterone responsiveness and the control of human parturition","volume":"11","author":"Mesiano","year":"2004","journal-title":"J\u00a0Soc Gynecol Investig"},{"key":"10.1016\/j.ajogmf.2020.100219_bib26","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.jri.2017.12.004","article-title":"Intrauterine inflammatory activation, functional progesterone withdrawal, and the timing of term and preterm birth","volume":"125","author":"Keelan","year":"2018","journal-title":"J\u00a0Reprod Immunol"},{"key":"10.1016\/j.ajogmf.2020.100219_bib27","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1177\/1933719116650756","article-title":"Progesterone receptor-mediated actions regulate remodeling of the cervix in preparation for preterm parturition","volume":"23","author":"Kirby","year":"2016","journal-title":"Reprod Sci"},{"key":"10.1016\/j.ajogmf.2020.100219_bib28","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/nrendo.2013.96","article-title":"MicroRNAs--mediators of myometrial contractility during pregnancy and labour","volume":"9","author":"Renthal","year":"2013","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.ajogmf.2020.100219_bib29","doi-asserted-by":"crossref","first-page":"223.e1","DOI":"10.1016\/j.ajog.2013.01.020","article-title":"Prevention of preterm birth by progestational agents: what are the molecular mechanisms?","volume":"208","author":"Nold","year":"2013","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2020.100219_bib30","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/j.1365-3016.2012.01303.x","article-title":"Validity of using ICD-9-CM codes to identify selected categories of obstetric complications, procedures and co-morbidities","volume":"26","author":"Goff","year":"2012","journal-title":"Paediatr Perinat Epidemiol"}],"container-title":["American Journal of Obstetrics & Gynecology MFM"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589933320301877?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589933320301877?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T23:47:56Z","timestamp":1762904876000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589933320301877"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["S2589933320301877"],"URL":"https:\/\/doi.org\/10.1016\/j.ajogmf.2020.100219","relation":{},"ISSN":["2589-9333"],"issn-type":[{"value":"2589-9333","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pregnancy duration with use of 17-\u03b1-hydroxyprogesterone caproate in a retrospective cohort at high risk of recurrent preterm birth","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics & Gynecology MFM","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajogmf.2020.100219","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"100219"}}