{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T18:40:45Z","timestamp":1764700845472,"version":"3.45.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000133","name":"Agency for Healthcare Research and Quality","doi-asserted-by":"publisher","award":["5T32HS000084-22"],"award-info":[{"award-number":["5T32HS000084-22"]}],"id":[{"id":"10.13039\/100000133","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajogmfm.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics & Gynecology MFM"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.ajogmf.2021.100311","type":"journal-article","created":{"date-parts":[[2021,1,22]],"date-time":"2021-01-22T11:28:53Z","timestamp":1611314933000},"page":"100311","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Prophylactic anticoagulation for preterm premature rupture of membranes: a decision analysis"],"prefix":"10.1016","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3725-7582","authenticated-orcid":false,"given":"Cassandra B.","family":"Iroz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carly M.","family":"Dahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irina R.","family":"Cassimatis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annie B.","family":"Wescott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily S.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajogmf.2021.100311_bib1","first-page":"e1","article-title":"ACOG Practice Bulletin No. 188: prelabor rupture of membranes","volume":"131","year":"2018","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib2","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.ogc.2005.03.003","article-title":"Preterm premature rupture of the membranes: current approaches to evaluation and management","volume":"32","author":"Mercer","year":"2005","journal-title":"Obstet Gynecol Clin North Am"},{"key":"10.1016\/j.ajogmf.2021.100311_bib3","doi-asserted-by":"crossref","first-page":"697","DOI":"10.7326\/0003-4819-143-10-200511150-00006","article-title":"Trends in the incidence of venous thromboembolism during pregnancy or postpartum: a 30-year population-based study","volume":"143","author":"Heit","year":"2005","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ajogmf.2021.100311_bib4","first-page":"730","article-title":"Incidence, clinical characteristics, and timing of objectively diagnosed venous thromboembolism during pregnancy","volume":"94","author":"Gherman","year":"1999","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib5","first-page":"595","article-title":"Thrombotic risk during pregnancy: a population Sudy","volume":"94","author":"Lindqvist","year":"1999","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib6","first-page":"56","article-title":"Venous thromboembolism in pregnancy and the puerperium: incidence and additional risk factors from a London perinatal database","volume":"108","author":"Simpson","year":"2001","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib7","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/j.ajog.2005.11.008","article-title":"Venous thromboembolism during pregnancy and the postpartum period: incidence, risk factors, and mortality","volume":"194","author":"James","year":"2006","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib8","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S1701-2163(16)34240-2","article-title":"Epidemiology of pregnancy-associated venous thromboembolism: a population-based study in Canada","volume":"31","author":"Liu","year":"2009","journal-title":"J\u00a0Obstet Gynaecol Can"},{"key":"10.1016\/j.ajogmf.2021.100311_bib9","doi-asserted-by":"crossref","first-page":"457.e1","DOI":"10.1016\/j.ajog.2007.04.022","article-title":"Antithrombotic therapy and pregnancy: consensus report and recommendations for prevention and treatment of venous thromboembolism and adverse pregnancy outcomes","volume":"197","author":"Duhl","year":"2007","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib10","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1097\/AOG.0b013e3181f3588d","article-title":"Effectiveness of timing strategies for delivery of individuals with placenta previa and accreta","volume":"116","author":"Robinson","year":"2010","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib11","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1097\/AOG.0b013e31820b0ace","article-title":"Effectiveness of timing strategies for delivery of individuals with vasa previa","volume":"117","author":"Robinson","year":"2011","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib12","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1097\/01.ogx.0000234860.76274.19","article-title":"Decision analysis in obstetrics and gynecology","volume":"61","author":"Grobman","year":"2006","journal-title":"Obstet Gynecol Surv"},{"key":"10.1016\/j.ajogmf.2021.100311_bib13","first-page":"57","article-title":"Length of latency with preterm premature rupture of membranes before 32 weeks\u2019 gestation","volume":"32","author":"Peaceman","year":"2015","journal-title":"Am J Perinatol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib14","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1001\/jama.1997.03550120049032","article-title":"Antibiotic therapy for reduction of infant morbidity After preterm premature rupture of the membranes: a randomized controlled trial","volume":"278","author":"Mercer","year":"1997","journal-title":"JAMA"},{"key":"10.1016\/j.ajogmf.2021.100311_bib15","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/0029-7844(95)00303-9","article-title":"Intentional delivery versus expectant management with preterm ruptured membranes at 30-34 weeks' gestation","volume":"86","author":"Cox","year":"1995","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib16","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/S0002-9378(15)33270-1","article-title":"Prospective randomized study of corticosteroids in the management of premature rupture of the membranes and the premature gestation","volume":"141","author":"Garite","year":"1981","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib17","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/0002-9378(85)90419-3","article-title":"Management of preterm prematurely ruptured membranes: a prospective randomized comparison of observation versus use of steroids and timed delivery","volume":"151","author":"Iams","year":"1985","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib18","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/0002-9378(93)90004-3","article-title":"Induction versus expectant management in premature rupture of the membranes with mature amniotic fluid at 32 to 36 weeks: a randomized trial","volume":"169","author":"Mercer","year":"1993","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib19","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S0002-9378(98)70638-6","article-title":"Premature rupture of membranes at 34 to 37 weeks\u2019 gestation: aggressive versus conservative management","volume":"178","author":"Naef","year":"1998","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib20","first-page":"55","article-title":"Premature Rupture of Membranes: A Prospective, Randomized Evaluation of Steroids, Latent Phase, and Expectant Management","volume":"66","author":"Nelson","year":"1985","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib21","first-page":"196","article-title":"Preterm premature rupture of the membranes with fetal pulmonary maturity present: a prospective study","volume":"69","author":"Spinnato","year":"1987","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib22","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD004735.pub3","article-title":"Planned early birth versus expectant management for women with preterm prelabour rupture of membranes prior to 37 weeks\u2019 gestation for improving pregnancy outcome","volume":"3","author":"Buchanan","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ajogmf.2021.100311_bib23","doi-asserted-by":"crossref","first-page":"3761","DOI":"10.1080\/14767058.2019.1585422","article-title":"Predictors for cesarean delivery in preterm premature rupture of membranes","volume":"33","author":"Salman","year":"2020","journal-title":"J\u00a0Matern Fetal Neonatal Med"},{"key":"10.1016\/j.ajogmf.2021.100311_bib24","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1111\/j.1471-0528.1983.tb06458.x","article-title":"The risks of antenatal subcutaneous heparin prophylaxis: a controlled trial","volume":"90","author":"Howell","year":"1983","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib25","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/j.ajog.2006.06.080","article-title":"Bone density changes in women who receive thromboprophylaxis in pregnancy","volume":"195","author":"Casele","year":"2006","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib26","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0049-3848(99)00110-3","article-title":"Thromboprophylaxis with low molecular weight heparin (dalteparin) in pregnancy","volume":"96","author":"Pettil\u00e4","year":"1999","journal-title":"Thromb Res"},{"key":"10.1016\/j.ajogmf.2021.100311_bib27","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD001689.pub3","article-title":"Prophylaxis for venous thromboembolic disease in pregnancy and the early postnatal period","author":"Bain","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ajogmf.2021.100311_bib28","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD001689.pub2","article-title":"Prophylaxis for venous thromboembolic disease in pregnancy and the early postnatal period","volume":"5","author":"Tooher","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ajogmf.2021.100311_bib29","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/s10995-005-0009-3","article-title":"Variations in the incidence of postpartum hemorrhage across hospitals in California","volume":"9","author":"Lu","year":"2005","journal-title":"Matern Child Health J"},{"key":"10.1016\/j.ajogmf.2021.100311_bib30","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1186\/s12884-015-0788-5","article-title":"Trends and outcomes of postpartum haemorrhage, 2003\u20132011","volume":"15","author":"Ford","year":"2015","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.ajogmf.2021.100311_bib31","doi-asserted-by":"crossref","first-page":"353.e1","DOI":"10.1016\/j.ajog.2010.01.011","article-title":"Trends in postpartum hemorrhage: United States, 1994-2006","volume":"202","author":"Callaghan","year":"2010","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib32","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1213\/ANE.0b013e3181d74898","article-title":"The epidemiology of postpartum hemorrhage in a large, nationwide sample of deliveries","volume":"110","author":"Bateman","year":"2010","journal-title":"Anesth Analg"},{"key":"10.1016\/j.ajogmf.2021.100311_bib33","doi-asserted-by":"crossref","first-page":"344.e1","DOI":"10.1016\/j.ajog.2017.05.004","article-title":"The impact of postpartum hemorrhage on hospital length of stay and inpatient mortality: a National Inpatient Sample\u2013based analysis","volume":"217","author":"Marshall","year":"2017","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib34","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1177\/1753495X14520849","article-title":"Haemorrhagic complications of peripartum anticoagulation: a retrospective chart review","volume":"7","author":"Wang","year":"2014","journal-title":"Obstet Med"},{"key":"10.1016\/j.ajogmf.2021.100311_bib35","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1182\/blood-2005-02-0626","article-title":"Low-molecular-weight heparins for thromboprophylaxis and treatment of venous thromboembolism in pregnancy: a systematic review of safety and efficacy","volume":"106","author":"Greer","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.ajogmf.2021.100311_bib36","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/j.1538-7836.2011.04186.x","article-title":"Prophylaxis with low-dose low-molecular-weight heparin during pregnancy and postpartum: is it effective?","volume":"9","author":"Roeters Van Lennep","year":"2011","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.ajogmf.2021.100311_bib37","doi-asserted-by":"crossref","first-page":"463","DOI":"10.2165\/00003495-200262030-00004","article-title":"Low molecular weight heparins: a guide to their optimum use in pregnancy","volume":"62","author":"Laurent","year":"2002","journal-title":"Drugs"},{"key":"10.1016\/j.ajogmf.2021.100311_bib38","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.ejogrb.2011.08.005","article-title":"Tinzaparin use in pregnancy: an international, retrospective study of the safety and efficacy profile","volume":"159","author":"Nelson-Piercy","year":"2011","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib39","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/sj.jp.7211745","article-title":"Low-molecular-weight heparin in pregnancy: peripartum bleeding complications","volume":"27","author":"Kominiarek","year":"2007","journal-title":"J\u00a0Perinatol"},{"key":"10.1016\/j.ajogmf.2021.100311_bib40","first-page":"1","article-title":"Low molecular weight heparin use during pregnancy and risk of postpartum hemorrhage: a systematic review and meta-analysis","author":"Sirico","year":"2018","journal-title":"J\u00a0Matern Fetal Neonatal Med"},{"key":"10.1016\/j.ajogmf.2021.100311_bib41","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1097\/AOG.0b013e31820093a9","article-title":"Anesthesia-related maternal mortality in the United States: 1979-2002","volume":"117","author":"Hawkins","year":"2011","journal-title":"Obstet Gynecol"}],"container-title":["American Journal of Obstetrics & Gynecology MFM"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589933321000069?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589933321000069?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T23:47:07Z","timestamp":1762904827000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589933321000069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":41,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["S2589933321000069"],"URL":"https:\/\/doi.org\/10.1016\/j.ajogmf.2021.100311","relation":{},"ISSN":["2589-9333"],"issn-type":[{"type":"print","value":"2589-9333"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prophylactic anticoagulation for preterm premature rupture of membranes: a decision analysis","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics & Gynecology MFM","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajogmf.2021.100311","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"100311"}}