{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T17:41:05Z","timestamp":1788543665937,"version":"build-2803163510"},"reference-count":48,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["ajogmfm.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics &amp; Gynecology MFM"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.ajogmf.2022.100659","type":"journal-article","created":{"date-parts":[[2022,5,11]],"date-time":"2022-05-11T13:54:08Z","timestamp":1652277248000},"page":"100659","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Maternal electronic cigarette exposure in relation to offspring development: a comprehensive review"],"prefix":"10.1016","volume":"4","author":[{"given":"Yijia","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghan","family":"Angley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinran","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E.","family":"D'Alton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ka","family":"Kahe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajogmf.2022.100659_bib0001","doi-asserted-by":"crossref","DOI":"10.1016\/j.drugalcdep.2020.108361","article-title":"Prevalence of e-cigarette use (2016 to 2018) and cigarette smoking (2012 to 2019) among U.S. adults by state: an interactive data visualization dashboard","volume":"218","author":"Kianersi","year":"2021","journal-title":"Drug Alcohol Depend"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0002","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1002\/bdra.23333","article-title":"Is there evidence for potential harm of electronic cigarette use in pregnancy?","volume":"103","author":"Suter","year":"2015","journal-title":"Birth Defects Res A Clin Mol Teratol"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0003","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.15585\/mmwr.mm6937e1","article-title":"E-cigarette use among middle and high school students - United States, 2020","volume":"69","author":"Wang","year":"2020","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0004","doi-asserted-by":"crossref","first-page":"389","DOI":"10.2217\/17455057.2.3.389","article-title":"Pregnancy, smoking and birth outcomes","volume":"2","author":"Delpisheh","year":"2006","journal-title":"Womens Health (Lond)"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0005","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1007\/s10995-016-2257-9","article-title":"Prevalence and perceptions of electronic cigarette use during pregnancy","volume":"21","author":"Wagner","year":"2017","journal-title":"Matern Child Health J"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0006","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1001\/jamapediatrics.2019.0658","article-title":"National estimates of e-cigarette use Among pregnant and nonpregnant women of reproductive age in the United States, 2014-2017","volume":"173","author":"Liu","year":"2019","journal-title":"JAMA Pediatr"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0007","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.amepre.2020.02.015","article-title":"E-cigarette use patterns and high-risk behaviors in pregnancy: behavioral risk factor surveillance system, 2016-2018","volume":"59","author":"Obisesan","year":"2020","journal-title":"Am J Prev Med"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0008","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.ypmed.2017.07.030","article-title":"Tobacco and nicotine delivery product use in a national sample of pregnant women","volume":"104","author":"Kurti","year":"2017","journal-title":"Prev Med"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0009","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.cotox.2019.05.001","article-title":"Impact of electronic cigarette aerosols on pregnancy and early development","volume":"14","author":"Orzabal","year":"2019","journal-title":"Curr Opin Toxicol"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0010","doi-asserted-by":"crossref","first-page":"35","DOI":"10.14423\/SMJ.0000000000000749","article-title":"E-cigarette toxicity?","volume":"111","author":"Tegin","year":"2018","journal-title":"South Med J"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0011","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1093\/ntr\/ntab017","article-title":"Vaping in pregnancy: a systematic review","volume":"23","author":"Calder","year":"2021","journal-title":"Nicotine Tob Res"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0012","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1177\/1753495X19893224","article-title":"Smoking and pregnancy: the era of electronic nicotine delivery systems","volume":"13","author":"Desai","year":"2020","journal-title":"Obstet Med"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0013","doi-asserted-by":"crossref","first-page":"13508","DOI":"10.1038\/s41598-021-92930-5","article-title":"Patterns of combustible and electronic cigarette use during pregnancy and associated pregnancy outcomes","volume":"11","author":"Regan","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0014","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1186\/s12884-020-03247-6","article-title":"Electronic cigarettes may not be a \u201csafer alternative\u201d of conventional cigarettes during pregnancy: evidence from the nationally representative PRAMS data","volume":"20","author":"Kim","year":"2020","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2021.105995","article-title":"E-cigarette vaping liquids and the flavoring chemical cinnamaldehyde perturb bone, cartilage and vascular development in zebrafish embryos","volume":"240","author":"Bhattacharya","year":"2021","journal-title":"Aquat Toxicol"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0016","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s43188-021-00103-3","article-title":"In utero exposure to electronic-cigarette aerosols decreases lung fibrillar collagen content, increases Newtonian resistance and induces sex-specific molecular signatures in neonatal mice","volume":"38","author":"Cahill","year":"2022","journal-title":"Toxicol Res"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0017","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1177\/0960327120947785","article-title":"In vivo assessment of the toxicity of electronic cigarettes to zebrafish (Danio rerio) embryos, following gestational exposure, in terms of mortality, developmental toxicity, and hair cell damage: toxicity of E-cigs to zebrafish embryos","volume":"40","author":"Chang","year":"2021","journal-title":"Hum Exp Toxicol"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0018","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1002\/bdr2.1951","article-title":"Cardiovascular function during early development is suppressed by cinnamon flavored, nicotine-free, electronic cigarette vapor","volume":"113","author":"Piechowski","year":"2021","journal-title":"Birth Defects Res"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2020.112911","article-title":"Effect of electronic cigarette aerosol exposure during gestation and lactation on learning and memory of adult male offspring rats","volume":"221","author":"Al-Sawalha","year":"2020","journal-title":"Physiol Behav"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0020","doi-asserted-by":"crossref","DOI":"10.1098\/rsbl.2020.0361","article-title":"Vape flavourants dull sensory perception and cause hyperactivity in developing zebrafish embryos","volume":"16","author":"Gauthier","year":"2020","journal-title":"Biol Lett"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0021","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.reprotox.2020.07.012","article-title":"Replacing smoking with vaping during pregnancy: impacts on metabolic health in mice","volume":"96","author":"Li","year":"2020","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0022","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1093\/toxsci\/kfz194","article-title":"Neurological effects in the offspring after switching from tobacco cigarettes to E-cigarettes during pregnancy in a mouse model","volume":"172","author":"Nguyen","year":"2019","journal-title":"Toxicol Sci"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0023","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.trsl.2019.01.001","article-title":"Chronic exposure to e-cig aerosols during early development causes vascular dysfunction and offspring growth deficits","volume":"207","author":"Orzabal","year":"2019","journal-title":"Transl Res"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0024","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/jnc.14947","article-title":"Prenatal electronic cigarette exposure decreases brain glucose utilization and worsens outcome in offspring hypoxic-ischemic brain injury","volume":"153","author":"Sifat","year":"2020","journal-title":"J Neurochem"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0025","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1210\/js.2019-00216","article-title":"E-cigarette exposure delays implantation and causes reduced weight gain in female offspring exposed in utero","volume":"3","author":"Wetendorf","year":"2019","journal-title":"J Endocr Soc"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0026","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.neulet.2018.07.001","article-title":"Modulation of neural regulators of energy homeostasis, and of inflammation, in the pups of mice exposed to e-cigarettes","volume":"684","author":"Chen","year":"2018","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0027","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1021\/acs.chemrestox.8b00084","article-title":"Maternal E-cigarette exposure results in cognitive and epigenetic alterations in offspring in a mouse model","volume":"31","author":"Nguyen","year":"2018","journal-title":"Chem Res Toxicol"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0028","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1165\/rcmb.2017-0206RC","article-title":"Maternal E-cigarette exposure in mice alters DNA methylation and lung cytokine expression in offspring","volume":"58","author":"Chen","year":"2018","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0029","article-title":"Associations between electronic nicotine delivery systems and birth outcomes","author":"Hawkins","year":"2021","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0030","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1097\/AOG.0000000000004432","article-title":"Adverse birth outcomes associated with prepregnancy and prenatal electronic cigarette use","volume":"138","author":"Regan","year":"2021","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0031","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2020.100602","article-title":"The effects of prenatal cigarette and e-cigarette exposure on infant neurobehaviour: a comparison to a control group","volume":"28","author":"Froggatt","year":"2020","journal-title":"EClinicalMedicine"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0032","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1111\/1471-0528.16110","article-title":"Electronic cigarettes and obstetric outcomes: a prospective observational study","volume":"127","author":"McDonnell","year":"2020","journal-title":"BJOG"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0033","doi-asserted-by":"crossref","DOI":"10.1016\/j.ypmed.2020.106041","article-title":"Smoking and use of electronic cigarettes (vaping) in relation to preterm birth and small-for-gestational-age in a 2016 U.S. national sample","volume":"134","author":"Wang","year":"2020","journal-title":"Prev Med"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0034","doi-asserted-by":"crossref","first-page":"44","DOI":"10.18332\/tid\/106089","article-title":"Use of electronic nicotine delivery systems (ENDS) by pregnant women I: risk of small-for-gestational-age birth","volume":"17","author":"Cardenas","year":"2019","journal-title":"Tob Induc Dis"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0035","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1203\/PDR.0b013e318186e609","article-title":"Zebrafish as a developmental model organism for pediatric research","volume":"64","author":"Veldman","year":"2008","journal-title":"Pediatr Res"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0036","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1093\/humupd\/dmr022","article-title":"Maternal smoking in pregnancy and birth defects: a systematic review based on 173 687 malformed cases and 11.7 million controls","volume":"17","author":"Hackshaw","year":"2011","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0037","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.psyneuen.2014.05.017","article-title":"Maternal smoking during pregnancy and infant stress response: test of a prenatal programming hypothesis","volume":"48","author":"Stroud","year":"2014","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0038","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1038\/s41398-019-0640-1","article-title":"Prenatal nicotine sex-dependently alters adolescent dopamine system development","volume":"9","author":"Dwyer","year":"2019","journal-title":"Transl Psychiatry"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0039","doi-asserted-by":"crossref","first-page":"36001","DOI":"10.1289\/EHP5686","article-title":"Metal\/metalloid levels in electronic cigarette liquids, aerosols, and human biosamples: a systematic review","volume":"128","author":"Zhao","year":"2020","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0040","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.ntt.2011.05.010","article-title":"Prenatal exposure to multiple toxic heavy metals and neonatal neurobehavioral development in Shanghai, China","volume":"33","author":"Yu","year":"2011","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0041","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1080\/15592294.2017.1320637","article-title":"Prenatal exposure to neurotoxic metals is associated with increased placental glucocorticoid receptor DNA methylation","volume":"12","author":"Appleton","year":"2017","journal-title":"Epigenetics"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0042","doi-asserted-by":"crossref","first-page":"363","DOI":"10.3109\/10408444.2013.792328","article-title":"A toxicological review of the propylene glycols","volume":"43","author":"Fowles","year":"2013","journal-title":"Crit Rev Toxicol"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0043","first-page":"105","article-title":"The toxic effects of formaldehyde on the nervous system","volume":"203","author":"Songur","year":"2010","journal-title":"Rev Environ Contam Toxicol"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0044","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.neuro.2018.02.007","article-title":"Neurobehavioral effects of 1,2-propanediol in zebrafish (Danio rerio)","volume":"65","author":"Massarsky","year":"2018","journal-title":"NeuroToxicology"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0045","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0118344","article-title":"The effects of electronic cigarette emissions on systemic cotinine levels, weight and postnatal lung growth in neonatal mice","volume":"10","author":"McGrath-Morrow","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0046","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0137953","article-title":"Adult behavior in male mice exposed to E-cigarette nicotine vapors during late prenatal and early postnatal life","volume":"10","author":"Smith","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0047","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1093\/toxsci\/kfx257","article-title":"Microglia activation and gene expression alteration of neurotrophins in the hippocampus following early-life exposure to E-cigarette aerosols in a murine model","volume":"162","author":"Zelikoff","year":"2018","journal-title":"Toxicol Sci"},{"key":"10.1016\/j.ajogmf.2022.100659_bib0048","unstructured":"National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Population Health and Public Health Practice; Committee on the Review of the Health Effects of Electronic Nicotine Delivery Systems; Eaton DL, Kwan LY, Stratton K, editors. Public Health Consequences of E-Cigarettes. Washington (DC): National Academies Press (US); 2018 Jan 23. 5, Toxicology of E-Cigarette Constituents. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK507184\/"}],"container-title":["American Journal of Obstetrics &amp; Gynecology MFM"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589933322000945?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589933322000945?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T23:50:35Z","timestamp":1762905035000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589933322000945"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":48,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["S2589933322000945"],"URL":"https:\/\/doi.org\/10.1016\/j.ajogmf.2022.100659","relation":{},"ISSN":["2589-9333"],"issn-type":[{"value":"2589-9333","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Maternal electronic cigarette exposure in relation to offspring development: a comprehensive review","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics & Gynecology MFM","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajogmf.2022.100659","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"100659"}}