{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T02:15:33Z","timestamp":1793153733772,"version":"4.5.0"},"reference-count":12,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["ajogmfm.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics & Gynecology MFM"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.ajogmf.2023.100997","type":"journal-article","created":{"date-parts":[[2023,6,2]],"date-time":"2023-06-02T16:13:38Z","timestamp":1685722418000},"page":"100997","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["A pilot randomized control trial of topical capsaicin as adjunctive therapy for nausea and vomiting of pregnancy"],"prefix":"10.1016","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9648-4294","authenticated-orcid":false,"given":"Lauren M.","family":"Murphy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna R.","family":"Whelan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurie B.","family":"Griffin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maureen S.","family":"Hamel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajogmf.2023.100997_bib0001","doi-asserted-by":"crossref","first-page":"S182","DOI":"10.1067\/mob.2002.122594","article-title":"Nausea and vomiting in pregnancy: the problem of perception\u2013is it really a disease?","volume":"186","author":"Miller","year":"2002","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2023.100997_bib0002","first-page":"e149","article-title":"Economic burden of nausea and vomiting of pregnancy in the USA","volume":"20","author":"Piwko","year":"2013","journal-title":"J Popul Ther Clin Pharmacol"},{"key":"10.1016\/j.ajogmf.2023.100997_bib0003","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1097\/AOG.0000000000002604","article-title":"ACOG Practice Bulletin 189: nausea and vomiting of pregnancy","volume":"131","author":"Erick","year":"2018","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2023.100997_bib0004","first-page":"94","article-title":"Hospitalizations during pregnancy among managed care enrollees","volume":"100","author":"Gazmararian","year":"2002","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2023.100997_bib0005","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1111\/acem.14062","article-title":"A pilot trial of topical capsaicin cream for treatment of cannabinoid hyperemesis syndrome","volume":"27","author":"Dean","year":"2020","journal-title":"Acad Emerg Med"},{"key":"10.1016\/j.ajogmf.2023.100997_bib0006","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1111\/j.1553-2712.2009.00581.x","article-title":"Use of the visual analog scale to rate and monitor severity of nausea in the emergency department","volume":"16","author":"Meek","year":"2009","journal-title":"Acad Emerg Med"},{"key":"10.1016\/j.ajogmf.2023.100997_bib0007","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1034\/j.1399-6576.2000.440420.x","article-title":"Assessment of postoperative nausea using a visual analogue scale","volume":"44","author":"Boogaerts","year":"2000","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1016\/j.ajogmf.2023.100997_bib0008","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.clnu.2015.02.011","article-title":"Capsaicin-containing chili improved postprandial hyperglycemia, hyperinsulinemia, and fasting lipid disorders in women with gestational diabetes mellitus and lowered the incidence of large-for-gestational-age newborns","volume":"35","author":"Yuan","year":"2016","journal-title":"Clin Nutr"},{"key":"10.1016\/j.ajogmf.2023.100997_bib0009","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1080\/09546630510041079","article-title":"Topical capsaicin for the treatment of acute lipodermatosclerosis and lobular panniculitis","volume":"16","author":"Yosipovitch","year":"2005","journal-title":"J Dermatolog Treat"},{"key":"10.1016\/j.ajogmf.2023.100997_bib0010","doi-asserted-by":"crossref","first-page":"50","DOI":"10.4103\/nms.nms_58_17","article-title":"The effects of capsaicin ointment application to the K-K9 acupressure point on nausea and vomiting during cesarean section under spinal anesthesia","volume":"7","author":"Abedian","year":"2018","journal-title":"Nurs Midwifery Stud"},{"key":"10.1016\/j.ajogmf.2023.100997_bib0011","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1080\/15563650.2017.1349910","article-title":"Cannabinoid hyperemesis syndrome: potential mechanisms for the benefit of capsaicin and hot water hydrotherapy in treatment","volume":"56","author":"Richards","year":"2018","journal-title":"Clin Toxicol (Phila)"},{"key":"10.1016\/j.ajogmf.2023.100997_bib0012","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0014-2999(97)01370-8","article-title":"Capsaicin in the 4th ventricle abolishes retching and transmission of emetic vagal afferents to solitary nucleus neurons","volume":"339","author":"Shiroshita","year":"1997","journal-title":"Eur J Pharmacol"}],"container-title":["American Journal of Obstetrics & Gynecology MFM"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589933323001398?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589933323001398?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T23:54:32Z","timestamp":1762905272000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589933323001398"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":12,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["S2589933323001398"],"URL":"https:\/\/doi.org\/10.1016\/j.ajogmf.2023.100997","relation":{},"ISSN":["2589-9333"],"issn-type":[{"value":"2589-9333","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A pilot randomized control trial of topical capsaicin as adjunctive therapy for nausea and vomiting of pregnancy","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics & Gynecology MFM","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajogmf.2023.100997","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"100997"}}