{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T08:55:03Z","timestamp":1785488103967,"version":"3.56.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["ajogmfm.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics & Gynecology MFM"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.ajogmf.2024.101541","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T20:33:19Z","timestamp":1731443599000},"page":"101541","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Role of prophylactic intravenous calcium in prevention of postspinal hypotension among women with preeclampsia undergoing cesarean delivery: a placebo controlled randomized clinical trial"],"prefix":"10.1016","volume":"7","author":[{"given":"Navin Kumar","family":"Yadav","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suman","family":"Lata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nivedita","family":"Jha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak","family":"Chakravarthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8968-9216","authenticated-orcid":false,"given":"Ajay Kumar","family":"Jha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.ajogmf.2024.101541_bib0001","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0207388","article-title":"Effect of anaesthetic technique on neonatal morbidity in emergency caesarean section for foetal distress","volume":"13","author":"Edipoglu","year":"2018","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.ajogmf.2024.101541_bib0002","first-page":"686","article-title":"Focused review: spinal anesthesia in severe preeclampsia","volume":"117","author":"Henke","year":"2013","journal-title":"AnesthAnalg"},{"issue":"3","key":"10.1016\/j.ajogmf.2024.101541_bib0003","doi-asserted-by":"crossref","first-page":"e11519","DOI":"10.5812\/aapm.11519","article-title":"Comparing the hemodynamic effects of spinal anesthesia in preeclamptic and healthy parturients during cesarean section","volume":"6","author":"Nikooseresht","year":"2016","journal-title":"Anesth Pain Med"},{"key":"10.1016\/j.ajogmf.2024.101541_bib0004","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s13037-020-00234-w","article-title":"Hemodynamic changes after spinal anesthesia in preeclamptic patients undergoing cesarean section at a tertiary referral center in Ethiopia: a prospective cohort study","volume":"14","author":"Alemayehu","year":"2020","journal-title":"Patient Saf Surg"},{"issue":"5","key":"10.1016\/j.ajogmf.2024.101541_bib0005","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1097\/01.anes.0000311153.84687.c7","article-title":"Hemodynamic changes associated with spinal anesthesia for cesarean delivery in severe preeclampsia","volume":"108","author":"Dyer","year":"2008","journal-title":"Anesthesiology"},{"issue":"10","key":"10.1016\/j.ajogmf.2024.101541_bib0006","doi-asserted-by":"crossref","first-page":"786","DOI":"10.2174\/1389201019666180925120109","article-title":"Preeclampsia\u2014current management and future approach","volume":"19","author":"Dymara-Konopka","year":"2018","journal-title":"Curr Pharm Biotechnol"},{"key":"10.1016\/j.ajogmf.2024.101541_bib0007","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1139\/y87-120","article-title":"Mg2+-Ca2+ interaction in contractility of vascular smooth muscle: Mg2+ versus organic calcium channel blockers on myogenic tone and agonist-induced responsiveness of blood vessels","volume":"65","author":"Altura","year":"1987","journal-title":"Can J Physiol Pharmacol"},{"issue":"1","key":"10.1016\/j.ajogmf.2024.101541_bib0008","doi-asserted-by":"crossref","first-page":"R27","DOI":"10.1530\/JOE-16-0340","article-title":"Vascular adaptation in pregnancy and endothelial dysfunction in preeclampsia","volume":"232","author":"Boeldt","year":"2017","journal-title":"J Endocrinol"},{"key":"10.1016\/j.ajogmf.2024.101541_bib0009","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/978-3-319-77932-4_28","article-title":"Cardiovascular sequels during and after preeclampsia","volume":"1065","author":"Paauw","year":"2018","journal-title":"Adv Exp Med Biol"},{"issue":"3","key":"10.1016\/j.ajogmf.2024.101541_bib0010","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.bpobgyn.2009.11.004","article-title":"Magnesium in obstetrics","volume":"24","author":"James","year":"2010","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"issue":"1","key":"10.1016\/j.ajogmf.2024.101541_bib0011","first-page":"104","article-title":"Intravenous calcium to decrease blood loss during intrapartum cesarean delivery: a randomized controlled trial","volume":"143","author":"Ansari","year":"2024","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2024.101541_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinane.2022.110796","article-title":"Calcium chloride for the prevention of uterine atony during cesarean delivery: a pilot randomized controlled trial and pharmacokinetic study","volume":"80","author":"Ansari","year":"2022","journal-title":"J Clin Anesth"},{"issue":"11","key":"10.1016\/j.ajogmf.2024.101541_bib0013","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1016\/j.bpj.2020.08.045","article-title":"Allosteric changes in the NMDA receptor associated with calcium-dependent inactivation","volume":"119","author":"Bhatia","year":"2020","journal-title":"Biophys J"},{"issue":"1","key":"10.1016\/j.ajogmf.2024.101541_bib0014","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1523\/JNEUROSCI.3791-04.2005","article-title":"A functional interaction of sodium and calcium in the regulation of NMDA receptor activity by remote NMDA receptors","volume":"25","author":"Xin","year":"2005","journal-title":"J Neurosci"},{"issue":"3","key":"10.1016\/j.ajogmf.2024.101541_bib0015","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.bpj.2023.12.018","article-title":"Calcium- and calmodulin-dependent inhibition of NMDA receptor currents","volume":"123","author":"Iacobucci","year":"2024","journal-title":"Biophys J"},{"key":"10.1016\/j.ajogmf.2024.101541_bib0016","unstructured":"National Institute for Care and Health Excellence guidelines (NG 192). Available at: https:\/\/www.nice.org.uk\/guidance\/ng192\/chapter\/recommendations. accessed 28 August 2024."},{"issue":"5","key":"10.1016\/j.ajogmf.2024.101541_bib0017","first-page":"1122","article-title":"Report of the American College of Obstetricians and Gynecologists' Task Force on hypertension in pregnancy","volume":"122","year":"2013","journal-title":"Obstet Gynecol"},{"issue":"Suppl 1","key":"10.1016\/j.ajogmf.2024.101541_bib0018","first-page":"90","article-title":"Spinal anaesthesia-induced hypotension in obstetrics: prevention and therapy","volume":"58","author":"\u0160klebar","year":"2019","journal-title":"Acta Clin Croat"},{"issue":"4","key":"10.1016\/j.ajogmf.2024.101541_bib0019","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1161\/STROKEAHA.108.527788","article-title":"Magnesium sulphate for the treatment of eclampsia: a brief review","volume":"40","author":"Euser","year":"2009","journal-title":"Stroke"},{"issue":"6","key":"10.1016\/j.ajogmf.2024.101541_bib0020","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1093\/bja\/ael085","article-title":"Magnesium sulphate as a technique of hypotensive anaesthesia","volume":"96","author":"Elsharnouby","year":"2006","journal-title":"Br J Anaesth"},{"issue":"5","key":"10.1016\/j.ajogmf.2024.101541_bib0021","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/j.bja.2020.11.020","article-title":"Association between ionised calcium and severity of postpartum haemorrhage: a retrospective cohort study","volume":"126","author":"Epstein","year":"2021","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.ajogmf.2024.101541_bib0022","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/325098","article-title":"Fetomaternal outcome in severe preeclamptic women undergoing emergency cesarean section under either general or spinal anesthesia","volume":"2014","author":"Chattopadhyay","year":"2014","journal-title":"J Pregnancy"},{"key":"10.1016\/j.ajogmf.2024.101541_bib0023","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1213\/ANE.0b013e3182373a3e","article-title":"A review of the impact of phenylephrine administration on maternal hemodynamics and maternal and neonatal outcomes in women undergoing cesarean delivery under spinal anesthesia","volume":"114","author":"Habib","year":"2012","journal-title":"Anesth Analg"},{"issue":"1","key":"10.1016\/j.ajogmf.2024.101541_bib0024","doi-asserted-by":"crossref","first-page":"89","DOI":"10.33314\/jnhrc.v20i01.3882","article-title":"Effect of intravenous calcium gluconate on prevention of post spinal hypotension during spinal anaesthesia for caesarean section: a randomized double-blind controlled study","volume":"20","author":"Agarwal","year":"2022","journal-title":"J Nepal Health Res Counc"},{"issue":"1","key":"10.1016\/j.ajogmf.2024.101541_bib0025","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/anae.16172","article-title":"Effects of phenylephrine on systemic and cerebral circulations in humans: a systematic review with mechanistic explanations","volume":"79","author":"Meng","year":"2024","journal-title":"Anaesthesia"},{"key":"10.1016\/j.ajogmf.2024.101541_bib0026","article-title":"Norepinephrine as a potential aggravator of symptomatic cerebral vasospasm: two cases and argument for milrinone therapy","volume":"2014","author":"Zeiler","year":"2014","journal-title":"Case Rep Crit Care"},{"issue":"2","key":"10.1016\/j.ajogmf.2024.101541_bib0027","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1017\/S0965539511000040","article-title":"Seizures in women with preeclampsia: mechanisms and management","volume":"22","author":"Cipolla","year":"2011","journal-title":"Fetal Matern Med Rev"}],"container-title":["American Journal of Obstetrics & Gynecology MFM"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589933324002672?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589933324002672?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T05:35:04Z","timestamp":1738647304000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589933324002672"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["S2589933324002672"],"URL":"https:\/\/doi.org\/10.1016\/j.ajogmf.2024.101541","relation":{},"ISSN":["2589-9333"],"issn-type":[{"value":"2589-9333","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of prophylactic intravenous calcium in prevention of postspinal hypotension among women with preeclampsia undergoing cesarean delivery: a placebo controlled randomized clinical trial","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics & Gynecology MFM","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajogmf.2024.101541","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101541"}}