{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T07:02:27Z","timestamp":1791874947062,"version":"4.3.4"},"reference-count":35,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["ajogmfm.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Obstetrics & Gynecology MFM"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.ajogmf.2025.101602","type":"journal-article","created":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T19:10:29Z","timestamp":1738005029000},"page":"101602","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Cerclage in singleton pregnancies with no prior spontaneous preterm birth and short cervix: a randomized controlled trial"],"prefix":"10.1016","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3705-6943","authenticated-orcid":false,"given":"Rupsa C.","family":"Boelig","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Tersigni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicoletta","family":"Di Simone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Saccone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Facchinetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Scambia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Berghella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajogmf.2025.101602_bib0001","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1016\/S0140-6736(23)00878-4","article-title":"National, regional, and global estimates of preterm birth in 2020, with trends from 2010: a systematic analysis","volume":"402","author":"Ohuma","year":"2023","journal-title":"Lancet"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0002","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/S2352-4642(21)00311-4","article-title":"Global, regional, and national causes of under-5 mortality in 2000\u201319: an updated systematic analysis with implications for the Sustainable Development Goals","volume":"6","author":"Perin","year":"2022","journal-title":"Lancet Child Adolesc Health"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0003","doi-asserted-by":"crossref","first-page":"233.e1","DOI":"10.1016\/j.ajog.2016.02.026","article-title":"Confirmed severe maternal morbidity is associated with high rate of preterm delivery","volume":"215","author":"Kilpatrick","year":"2016","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0004","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1186\/s12916-022-02659-9","article-title":"Longitudinal risk of maternal hospitalization for mental illness following preterm birth","volume":"20","author":"C\u00f4t\u00e9-Corriveau","year":"2022","journal-title":"BMC Med"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0005","doi-asserted-by":"crossref","first-page":"e1048","DOI":"10.1542\/peds.2005-2637","article-title":"Maternal birthplace and breastfeeding initiation among term and preterm infants: a statewide assessment for Massachusetts","volume":"118","author":"Merewood","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0006","doi-asserted-by":"crossref","first-page":"275.e1","DOI":"10.1016\/j.ajog.2011.06.043","article-title":"Influence of gestational age and reason for prior preterm birth on rates of recurrent preterm delivery","volume":"205","author":"Gonzalez-Quintero","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0007","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1111\/1471-0528.14906","article-title":"Risk of stillbirth, preterm delivery, and fetal growth restriction following exposure in a previous birth: systematic review and meta-analysis","volume":"125","author":"Malacova","year":"2018","journal-title":"BJOG"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0008","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.ejogrb.2018.06.018","article-title":"Spontaneous and iatrogenic preterm birth rates among unselected women in three consecutive pregnancies","volume":"228","author":"Kamphuis","year":"2018","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0009","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1053\/j.semperi.2017.07.009","article-title":"Epidemiology of preterm birth","volume":"41","author":"Purisch","year":"2017","journal-title":"Semin Perinatol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0010","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1161\/CIRCULATIONAHA.117.031403","article-title":"Association of spontaneous preterm delivery and future maternal cardiovascular disease","volume":"137","author":"Minissian","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0011","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/clc.22887","article-title":"Adverse pregnancy outcomes and future maternal cardiovascular disease","volume":"41","author":"Hauspurg","year":"2018","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0012","first-page":"1","article-title":"Births: final data for 2019","volume":"70","author":"Martin","year":"2021","journal-title":"Natl Vital Stat Rep"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0013","first-page":"1","article-title":"Cause-of-death data from the fetal death file, 2015\u20132017","volume":"69","author":"Hoyert","year":"2020","journal-title":"Natl Vital Stat Rep"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0014","article-title":"Multicenter randomized trial of cerclage for preterm birth prevention in high-risk women with shortened midtrimester cervical length","volume":"201","author":"Owen","year":"2009","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0015","doi-asserted-by":"crossref","first-page":"e65","DOI":"10.1097\/AOG.0000000000004479","article-title":"Prediction and prevention of spontaneous preterm birth: ACOG Practice Bulletin, number 234","volume":"138","year":"2021","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0016","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1002\/uog.26020","article-title":"ISUOG Practice Guidelines: role of ultrasound in the prediction of spontaneous preterm birth","volume":"60","author":"Coutinho","year":"2022","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2021.02.017","article-title":"Cervical length distribution and other sonographic ancillary findings of singleton nulliparous patients at midgestation","volume":"225","author":"Costantine","year":"2021","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0018","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1097\/AOG.0000000000000428","article-title":"A universal transvaginal cervical length screening program for preterm Birth prevention","volume":"124","author":"Orzechowski","year":"2014","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0019","doi-asserted-by":"crossref","first-page":"2840","DOI":"10.3109\/14767058.2015.1105957","article-title":"Cervical length, risk factors, and delivery outcomes among women with spontaneous preterm birth","volume":"29","author":"Boelig","year":"2016","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0020","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1001\/jama.2017.1373","article-title":"Predictive accuracy of serial transvaginal cervical lengths and quantitative vaginal fetal fibronectin levels for spontaneous preterm birth among nulliparous women","volume":"317","author":"Esplin","year":"2017","journal-title":"JAMA"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0021","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.ajog.2017.11.576","article-title":"Vaginal progesterone for preventing preterm birth and adverse perinatal outcomes in singleton gestations with a short cervix: a meta-analysis of individual patient data","volume":"218","author":"Romero","year":"2018","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0022","article-title":"Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy","volume":"6","author":"Alfirevic","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0023","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1002\/uog.17457","article-title":"Cerclage for sonographic short cervix in singleton gestations without prior spontaneous preterm birth: a systematic review and meta-analysis of trials using individual patient-level data","volume":"50","author":"Berghella","year":"2017","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0024","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1002\/uog.18908","article-title":"Prevention of preterm Birth with Pessary in Singletons (PoPPS): randomized controlled trial","volume":"51","author":"Dugoff","year":"2018","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0025","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1001\/jama.2023.10812","article-title":"Cervical pessary for prevention of preterm birth in individuals with a short cervix: the TOPS randomized clinical trial","volume":"330","author":"Hoffman","year":"2023","journal-title":"JAMA"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0026","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1002\/uog.9017","article-title":"Vaginal progesterone reduces the rate of preterm birth in women with a sonographic short cervix: a multicenter, randomized, double-blind, placebo-controlled trial","volume":"38","author":"Hassan","year":"2011","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0027","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbi.2019.103208","article-title":"The REDCap consortium: building an international community of software partners","volume":"95","author":"Harris","year":"2019","journal-title":"J Biomed Inform"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0028","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1097\/AOG.0b013e31820ca847","article-title":"Cerclage for short cervix on ultrasonography in women with singleton gestations and previous preterm birth: a meta-analysis","volume":"117","author":"Berghella","year":"2011","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajogmf.2023.101024","article-title":"Combined vaginal progesterone and cervical cerclage in the prevention of preterm birth: a systematic review and meta-analysis","volume":"5","author":"Aubin","year":"2023","journal-title":"Am J Obstet Gynecol MFM"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajogmf.2024.101351","article-title":"Concurrent Progestogen and cerclage to Reduce preterm Birth: a multicenter international retrospective cohort","volume":"6","author":"Tolosa","year":"2024","journal-title":"Am J Obstet Gynecol MFM"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0031","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/S0140-6736(21)00217-8","article-title":"Evaluating Progestogens for Preventing preterm birth International Collaborative (EPPPIC): meta-analysis of individual participant data from randomised controlled trials","volume":"397","author":"Group","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0032","doi-asserted-by":"crossref","first-page":"B2","DOI":"10.1016\/j.ajog.2024.05.006","article-title":"SMFM Publications Committee. SMFM consult series #70: management of short cervix in individuals without a history of spontaneous preterm birth","volume":"231","author":"Biggio","year":"2024","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0033","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.ajog.2015.10.934","article-title":"Prevention of preterm birth with vaginal progesterone or 17-alpha-hydroxyprogesterone caproate: a critical examination of efficacy and safety","volume":"214","author":"O'Brien","year":"2016","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0034","doi-asserted-by":"crossref","first-page":"846.e1","DOI":"10.1016\/j.ajog.2015.08.010","article-title":"Vaginal progesterone, but not 17\u03b1-hydroxyprogesterone caproate, has antiinflammatory effects at the murine maternal-fetal interface","volume":"213","author":"Furcron","year":"2015","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajogmf.2025.101602_bib0035","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1002\/uog.7338","article-title":"Effect of progesterone on cervical shortening in women at risk for preterm birth: secondary analysis from a multinational, randomized, double-blind, placebo-controlled trial","volume":"34","author":"O'Brien","year":"2009","journal-title":"Ultrasound Obstet Gynecol"}],"container-title":["American Journal of Obstetrics & Gynecology MFM"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589933325000035?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589933325000035?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,20]],"date-time":"2025-03-20T00:37:46Z","timestamp":1742431066000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589933325000035"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":35,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["S2589933325000035"],"URL":"https:\/\/doi.org\/10.1016\/j.ajogmf.2025.101602","relation":{},"ISSN":["2589-9333"],"issn-type":[{"value":"2589-9333","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cerclage in singleton pregnancies with no prior spontaneous preterm birth and short cervix: a randomized controlled trial","name":"articletitle","label":"Article Title"},{"value":"American Journal of Obstetrics & Gynecology MFM","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajogmf.2025.101602","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101602"}}