{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:30:30Z","timestamp":1786984230407,"version":"build-2736575974"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Asian Journal of Psychiatry"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1016\/j.ajp.2017.11.027","type":"journal-article","created":{"date-parts":[[2017,11,29]],"date-time":"2017-11-29T17:00:12Z","timestamp":1511974812000},"page":"29-33","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Association study of methylenetetrahydrofolate reductase genetic polymorphism 677C>T with schizophrenia in hospitalized patients in population of European Russia"],"prefix":"10.1016","volume":"32","author":[{"given":"T.V.","family":"Zhilyaeva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.V.","family":"Sergeeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.S.","family":"Blagonravova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.N.","family":"Kasimova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.V.","family":"Kuznetsov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.I.","family":"Golovanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.B.","family":"Shebolkova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.A.","family":"Korshunova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.ajp.2017.11.027_bib0005","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1038\/ng.171","article-title":"Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database","volume":"40","author":"Allen","year":"2008","journal-title":"Nat. Genet."},{"issue":"4","key":"10.1016\/j.ajp.2017.11.027_bib0010","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1093\/schbul\/6.4.606","article-title":"Catamnestic long-term study on the course of life and aging of schizophrenics","volume":"6","author":"Ciompi","year":"1980","journal-title":"Schizophr. Bull."},{"issue":"1","key":"10.1016\/j.ajp.2017.11.027_bib0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/aje\/kwj347","article-title":"Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE review","volume":"165","author":"Gilbody","year":"2007","journal-title":"Am. J. Epidemiol."},{"issue":"6","key":"10.1016\/j.ajp.2017.11.027_bib0020","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/j.pnpbp.2007.05.011","article-title":"Plasma homocysteine, folate and B12 in chronic schizophrenia","volume":"31","author":"Haidemenos","year":"2007","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"4","key":"10.1016\/j.ajp.2017.11.027_bib0025","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1093\/schbul\/14.4.633","article-title":"Course types in schizophrenia: an analysis of European and American studies","volume":"14","author":"Harding","year":"1988","journal-title":"Schizophr. Bull."},{"issue":"3","key":"10.1016\/j.ajp.2017.11.027_bib0030","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/sj.mp.4000724","article-title":"Association between the methylenetetrahydrofolate reductase 677C\u2192T missense mutation and schizophrenia","volume":"5","author":"Joober","year":"2000","journal-title":"Mol. Psychiatry"},{"issue":"2","key":"10.1016\/j.ajp.2017.11.027_bib0035","doi-asserted-by":"crossref","first-page":"134","DOI":"10.4306\/pi.2011.8.2.134","article-title":"Serum homocysteine and folate levels in korean schizophrenic patients","volume":"8","author":"Kim","year":"2011","journal-title":"Psychiatry Investig."},{"issue":"2","key":"10.1016\/j.ajp.2017.11.027_bib0040","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/sj.mp.4001746","article-title":"Homocysteine, methylenetetrahydrofolate reductase and risk of schizophrenia: a meta-analysis","volume":"11","author":"Muntjewerff","year":"2006","journal-title":"Mol. Psychiatry"},{"issue":"1\u20133","key":"10.1016\/j.ajp.2017.11.027_bib0045","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.schres.2007.01.003","article-title":"Effects of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism on executive function in schizophrenia","volume":"92","author":"Roffman","year":"2007","journal-title":"Schizophr. Res."},{"issue":"1","key":"10.1016\/j.ajp.2017.11.027_bib0050","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.biopsych.2006.12.017","article-title":"Contribution of methylenetetrahydrofolate reductase (MTHFR) polymorphisms to negative symptoms in schizophrenia","volume":"63","author":"Roffman","year":"2008","journal-title":"Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.ajp.2017.11.027_bib0055","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s11682-010-9111-2","article-title":"MTHFR 677C>T effects on anterior cingulate structure and function during response monitoring in schizophrenia: a preliminary study","volume":"5","author":"Roffman","year":"2011","journal-title":"Brain Imaging Behav."},{"issue":"2","key":"10.1016\/j.ajp.2017.11.027_bib0060","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1093\/schbul\/sbr150","article-title":"Genetic variation throughout the folate metabolic pathway influences negative symptom severity in schizophrenia","volume":"39","author":"Roffman","year":"2011","journal-title":"Schizophrenia Bull."},{"key":"10.1016\/j.ajp.2017.11.027_bib0065","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1002\/ajmg.b.32104","article-title":"Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age at onset of schizophrenia: no consistent evidence for an association in the Nordic population","volume":"159B","author":"Saetre","year":"2012","journal-title":"Am. J. Med. Genet. Part B"},{"issue":"7","key":"10.1016\/j.ajp.2017.11.027_bib0070","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/j.pnpbp.2005.06.022","article-title":"Association of the C677T and A1298C polymorphisms of methylenetetrahydrofolate reductase gene with schizophrenia: association is significant in men but not in women","volume":"29","author":"Sazci","year":"2005","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry."},{"issue":"4","key":"10.1016\/j.ajp.2017.11.027_bib0075","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1097\/00041444-200412000-00012","article-title":"Genetic analysis of the thermolabile methylenetetrahydrofolate reductase variant in schizophrenia and mood disorders","volume":"14","author":"Tan","year":"2004","journal-title":"Psychiatr. Genet."},{"issue":"2","key":"10.1016\/j.ajp.2017.11.027_bib0080","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1002\/ajmg.b.31030","article-title":"Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia","volume":"153B","author":"Vares","year":"2010","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"key":"10.1016\/j.ajp.2017.11.027_bib0085","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.ajp.2016.02.002","article-title":"Role of MTHFR C677T gene polymorphism in the susceptibility of schizophrenia: an updated meta-analysis","volume":"20","author":"Yadav","year":"2016","journal-title":"Asian J. Psychiatr."},{"issue":"1\u20133","key":"10.1016\/j.ajp.2017.11.027_bib0090","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.schres.2010.07.011","article-title":"Gene-wide association study between the methylenetetrahydrofolate reductase gene (MTHFR) and schizophrenia in the Japanese population, with an updated meta-analysis on currently available data","volume":"124","author":"Yoshimi","year":"2010","journal-title":"Schizophr. Res."},{"issue":"3","key":"10.1016\/j.ajp.2017.11.027_bib0095","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1097\/01.ypg.0000199444.77291.e2","article-title":"C677T and A1298C methylenetetrahydrofolate reductase gene polymorphisms in schizophrenia, bipolar disorder and depression: a meta-analysis of genetic association studies","volume":"16","author":"Zintzaras","year":"2006","journal-title":"Psychiatr. Genet"}],"container-title":["Asian Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1876201817304756?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1876201817304756?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T16:29:41Z","timestamp":1761755381000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1876201817304756"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":19,"alternative-id":["S1876201817304756"],"URL":"https:\/\/doi.org\/10.1016\/j.ajp.2017.11.027","relation":{},"ISSN":["1876-2018"],"issn-type":[{"value":"1876-2018","type":"print"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association study of methylenetetrahydrofolate reductase genetic polymorphism 677C>T with schizophrenia in hospitalized patients in population of European Russia","name":"articletitle","label":"Article Title"},{"value":"Asian Journal of Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajp.2017.11.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}