{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:13:50Z","timestamp":1791357230225,"version":"4.3.1"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004252","name":"Qatar University","doi-asserted-by":"publisher","award":["QUST-2-CPH-2017-9"],"award-info":[{"award-number":["QUST-2-CPH-2017-9"]}],"id":[{"id":"10.13039\/501100004252","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Asian Journal of Psychiatry"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.ajp.2018.12.011","type":"journal-article","created":{"date-parts":[[2018,12,21]],"date-time":"2018-12-21T20:00:01Z","timestamp":1545422401000},"page":"93-97","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"special_numbering":"C","title":["A qualitative exploration of clozapine prescribing and monitoring practices in the Arabian Gulf countries"],"prefix":"10.1016","volume":"39","author":[{"given":"Dalia","family":"Ismail","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2221-3387","authenticated-orcid":false,"given":"Karawen","family":"Tounsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Zolezzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5110-784X","authenticated-orcid":false,"given":"Yassin","family":"Eltorki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajp.2018.12.011_bib0005","doi-asserted-by":"crossref","first-page":"897","DOI":"10.2147\/NDT.S100405","article-title":"Patterns of psychotropic medication use in inpatient and outpatient psychiatric settings in Saudi Arabia","volume":"12","author":"Alhabbad","year":"2016","journal-title":"Neuropsychiatr. Dis. Treat."},{"issue":"04","key":"10.1016\/j.ajp.2018.12.011_bib0010","doi-asserted-by":"crossref","first-page":"276","DOI":"10.4236\/ijcm.2012.34054","article-title":"Psychotropic drug prescribing trends in Bahrain: implications for sexual functions","volume":"3","author":"Al-Khaja","year":"2012","journal-title":"Int. J. Clin. Med."},{"issue":"6","key":"10.1016\/j.ajp.2018.12.011_bib0015","article-title":"Utilization pattern of antipsychotics at a tertiary care hospital in Oman","volume":"17","author":"Al-Za\u2019abi","year":"2014","journal-title":"Afr. J. Psychiatry (Johannesbg)"},{"issue":"4","key":"10.1016\/j.ajp.2018.12.011_bib0020","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1192\/bjp.169.4.483","article-title":"Neutropenia and agranulocytosis in patients receiving clozapine in the UK and Ireland","volume":"169","author":"Atkin","year":"1996","journal-title":"Br. J. Psychiatry"},{"issue":"6","key":"10.1016\/j.ajp.2018.12.011_bib0025","doi-asserted-by":"crossref","first-page":"436","DOI":"10.4212\/cjhp.v67i6.1406","article-title":"Qualitative research: getting started","volume":"67","author":"Austin","year":"2014","journal-title":"Can. J. Hosp. Pharm."},{"key":"10.1016\/j.ajp.2018.12.011_bib0030","series-title":"Clozapine and the Risk of Neutropenia: an Overview for the Healthcare Provider","author":"Clozapine Risk Evaluation and Mitigation Strategy (REMS)","year":"2014"},{"issue":"5","key":"10.1016\/j.ajp.2018.12.011_bib0035","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1177\/2042098618756261","article-title":"Safety of antipsychotics for the treatment of schizophrenia: a focus on the adverse effects of clozapine","volume":"9","author":"De Berardis","year":"2018","journal-title":"Ther. Adv. Drug Saf."},{"issue":"2","key":"10.1016\/j.ajp.2018.12.011_bib0040","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1136\/eb-2014-101813","article-title":"Pharmacotherapy of treatment-resistant schizophrenia: a clinical perspective","volume":"17","author":"Dold","year":"2014","journal-title":"Evid Based Mental Health"},{"issue":"11","key":"10.1016\/j.ajp.2018.12.011_bib0045","doi-asserted-by":"crossref","DOI":"10.1176\/appi.ps.54.11.1453","article-title":"Psychopharmacology: underuse of evidence-based treatments in psychiatry","volume":"54","author":"Fayek","year":"2003","journal-title":"Psychiatr. Serv."},{"issue":"11","key":"10.1016\/j.ajp.2018.12.011_bib0050","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1176\/appi.ps.201500506","article-title":"Organizational characteristics of Veterans Affairs clinics with high and low utilization of clozapine","volume":"67","author":"G\u00f6ren","year":"2016","journal-title":"Psychiatr. Serv."},{"issue":"9","key":"10.1016\/j.ajp.2018.12.011_bib0055","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1177\/0269881112443744","article-title":"Choice of randomization to clozapine versus other second generation antipsychotics in the CATIE schizophrenia trial","volume":"26","author":"Hermes","year":"2012","journal-title":"J. Psychopharmacol. (Oxford)"},{"key":"10.1016\/j.ajp.2018.12.011_bib0060","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1007\/BF00442551","article-title":"The history of clozapine","volume":"99","author":"Hippius","year":"1989","journal-title":"Psychopharmacology"},{"issue":"1","key":"10.1016\/j.ajp.2018.12.011_bib0065","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/j.1447-0349.2007.00506.x","article-title":"Side effects and treatment with clozapine: a comparison between the views of consumers and their clinicians","volume":"17","author":"Hodge","year":"2008","journal-title":"Int. J. Ment. Health Nurs."},{"issue":"suppl 3","key":"10.1016\/j.ajp.2018.12.011_bib0070","first-page":"3","article-title":"Reducing clozapine-related morbidity and mortality: 5 years of experience with the Clozaril National Registry","volume":"59","author":"Honigfeld","year":"1998","journal-title":"J. Clin. Psychiatry"},{"issue":"6","key":"10.1016\/j.ajp.2018.12.011_bib0075","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1192\/bjp.bp.111.105833","article-title":"Adherence to treatment guidelines in clinical practice: study of antipsychotic treatment prior to clozapine initiation","volume":"201","author":"Howes","year":"2012","journal-title":"Br. J. Psychiatry"},{"issue":"1","key":"10.1016\/j.ajp.2018.12.011_bib0080","first-page":"92","article-title":"Why Not Clozapine? Clin Schizophrenia Relat","volume":"1","author":"Kelly","year":"2007","journal-title":"Psychoses"},{"issue":"7","key":"10.1016\/j.ajp.2018.12.011_bib0085","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1177\/0269881108100320","article-title":"Psychiatrists\u2019 attitude towards and knowledge of clozapine treatment","volume":"24","author":"Nielsen","year":"2010","journal-title":"J. Psychopharmacol. (Oxford)"},{"issue":"6","key":"10.1016\/j.ajp.2018.12.011_bib0090","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1192\/bjp.bp.112.114777","article-title":"Clinician hesitation prior to clozapine initiation: is it justifiable?","volume":"201","author":"Patel","year":"2012","journal-title":"Br. J. Psychiatry"},{"issue":"9","key":"10.1016\/j.ajp.2018.12.011_bib0095","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1177\/0706743717720448","article-title":"Guidelines for the pharmacotherapy of schizophrenia in adults","volume":"62","author":"Remington","year":"2017","journal-title":"Can. J. Psychiatry"},{"key":"10.1016\/j.ajp.2018.12.011_bib0100","series-title":"Interpretative Phenomenological Analysis: Theory, Method and Research","author":"Smith","year":"2009"},{"key":"10.1016\/j.ajp.2018.12.011_bib0105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.schres.2008.10.011","article-title":"Results of phase 3 of the CATIE schizophrenia trial","volume":"107","author":"Stroup","year":"2009","journal-title":"Schizophr. Res."},{"issue":"2","key":"10.1016\/j.ajp.2018.12.011_bib0110","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1176\/appi.ps.201300180","article-title":"Geographic and clinical variation in clozapine use in the United States","volume":"65","author":"Stroup","year":"2014","journal-title":"Psychiatr. Serv."},{"issue":"1","key":"10.1016\/j.ajp.2018.12.011_bib0115","doi-asserted-by":"crossref","first-page":"30","DOI":"10.4088\/JCP.v64n0107","article-title":"Prior antipsychotic prescribing in patients currently receiving clozapine: a case note review","volume":"64","author":"Taylor","year":"2003","journal-title":"J. Clin. Psychiatry"},{"issue":"2","key":"10.1016\/j.ajp.2018.12.011_bib0120","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1177\/2045125314566808","article-title":"Clozapine prescribing in the UK: views and experience of consultant psychiatrists","volume":"5","author":"Tungaraza","year":"2015","journal-title":"Ther. Adv. Psychopharmacol."},{"key":"10.1016\/j.ajp.2018.12.011_bib0125","series-title":"Drug Safety Communication. FDA Modifies Monitoring for Neutropenia Associated With Schizophrenia Medicine Clozapine; Approves New Shared REMS Program for All Clozapine Medicines","author":"United States Food and Drug Administration (FDA)","year":"2015"},{"issue":"1","key":"10.1016\/j.ajp.2018.12.011_bib0130","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1186\/1471-244X-14-102","article-title":"Clozapine: a review of clinical practice guidelines and prescribing trends","volume":"14","author":"Warnez","year":"2014","journal-title":"BMC Psychiatry"},{"issue":"6","key":"10.1016\/j.ajp.2018.12.011_bib0135","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1345\/aph.1K662","article-title":"Treatment pathway and patterns of clozapine prescribing for schizophrenia in New Zealand","volume":"42","author":"Wheeler","year":"2008","journal-title":"Ann. Pharmacother."},{"key":"10.1016\/j.ajp.2018.12.011_bib0140","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1111\/j.1365-2753.2008.01032.x","article-title":"Impact of audit and feedback on antipsychotic prescribing in schizophrenia","volume":"15","author":"Wheeler","year":"2009","journal-title":"J. Eval. Clin. Pract."},{"issue":"14","key":"10.1016\/j.ajp.2018.12.011_bib0145","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.2146\/ajhp110461","article-title":"Development of an outpatient pharmacist-managed clozapine clinic","volume":"69","author":"Williams","year":"2012","journal-title":"Am. J. Health. Syst. Pharm."}],"container-title":["Asian Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1876201818309730?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1876201818309730?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T16:33:07Z","timestamp":1761755587000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1876201818309730"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":29,"alternative-id":["S1876201818309730"],"URL":"https:\/\/doi.org\/10.1016\/j.ajp.2018.12.011","relation":{},"ISSN":["1876-2018"],"issn-type":[{"value":"1876-2018","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A qualitative exploration of clozapine prescribing and monitoring practices in the Arabian Gulf countries","name":"articletitle","label":"Article Title"},{"value":"Asian Journal of Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajp.2018.12.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}