{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T16:40:51Z","timestamp":1785516051048,"version":"3.56.0"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Asian Journal of Psychiatry"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.ajp.2024.104090","type":"journal-article","created":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T16:18:21Z","timestamp":1716308301000},"page":"104090","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Efficacy and safety of peri-partum Esketamine for prevention of post-partum depression in women undergoing caesarian section: A meta-analysis and systematic review of randomized controlled trials"],"prefix":"10.1016","volume":"97","author":[{"given":"Muhammad Anas","family":"Nayyer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suchna Meeral","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Umer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haim","family":"Imran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salman","family":"Khalid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Murtaza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arbab","family":"Sarfraz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noor","family":"Atiq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamna","family":"Rasool","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madah","family":"Fatima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajp.2024.104090_bib1","article-title":"A.n.dThe effect of ketamine on preventing postpartum depressionJOURNAL of MEDICINE and LIFE14https:\/\/doi.org\/10.25122\/jml-2020\u20130116","author":"Alipoor","year":"2013","journal-title":"O\u2019Hara"},{"key":"10.1016\/j.ajp.2024.104090_bib2","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyg.2021.648691","article-title":"Intranasal ketamine for depression in adults: a systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials","volume":"12","author":"An","year":"2021","journal-title":"Front. Psychol."},{"key":"10.1016\/j.ajp.2024.104090_bib3","article-title":"Zuranolone: The First FDA-approved oral treatment option for postpartum depression","author":"Barnes","year":"2023","journal-title":"Ann. Pharmacother."},{"key":"10.1016\/j.ajp.2024.104090_bib4","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1007\/s40263-019-00672-w","article-title":"Using Matching-Adjusted Indirect Comparisons and Network Meta-analyses to Compare Efficacy of Brexanolone Injection with Selective Serotonin Reuptake Inhibitors for Treating Postpartum Depression","volume":"33","author":"Cooper","year":"2019","journal-title":"CNS Drugs"},{"key":"10.1016\/j.ajp.2024.104090_bib5","doi-asserted-by":"crossref","first-page":"20901","DOI":"10.4088\/JCP.15r10174","article-title":"The Perinatal Depression Treatment Cascade: Baby Steps Toward Improving Outcomes","volume":"77","author":"Cox","year":"2016","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.ajp.2024.104090_bib6","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1176\/appi.ajp.20220785","article-title":"Zuranolone for the Treatment of Postpartum Depression","volume":"180","author":"Deligiannidis","year":"2023","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.ajp.2024.104090_bib7","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s40272-023-00561-2","article-title":"Benefits and Risks of Antidepressant Drugs During Pregnancy: A Systematic Review of Meta-analyses","volume":"25","author":"Desaunay","year":"2023","journal-title":"Paediatr. Drugs"},{"key":"10.1016\/j.ajp.2024.104090_bib8","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1038\/s41380-018-0256-5","article-title":"Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD)","volume":"25","author":"Fava","year":"2020","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.ajp.2024.104090_bib9","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/XEB.0000000000000141","article-title":"A new improved graphical and quantitative method for detecting bias in meta-analysis","volume":"16","author":"Furuya-Kanamori","year":"2018","journal-title":"Int. J. Evid. -Based Healthc."},{"key":"10.1016\/j.ajp.2024.104090_bib10","doi-asserted-by":"crossref","first-page":"4900","DOI":"10.3390\/ijerph19084900","article-title":"Associations among Caesarean Section Birth, Post-Traumatic Stress, and Postpartum Depression Symptoms","volume":"19","author":"Grisbrook","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.ajp.2024.104090_bib11","doi-asserted-by":"crossref","DOI":"10.1186\/s12871-022-01588-7","article-title":"S-ketamine as an adjuvant in patient-controlled intravenous analgesia for preventing postpartum depression: a randomized controlled trial","volume":"22","author":"Han","year":"2022","journal-title":"BMC Anesthesiol."},{"key":"10.1016\/j.ajp.2024.104090_bib12","doi-asserted-by":"crossref","first-page":"3116","DOI":"10.1038\/s41380-022-01587-7","article-title":"Ketamine: anesthetic, psychotomimetic, antidepressant, or anthelmintic?","volume":"27","author":"Hashimoto","year":"2022","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.ajp.2024.104090_bib13","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1016\/S0140-6736(14)61276-9","article-title":"Non-psychotic mental disorders in the perinatal period","volume":"384","author":"Howard","year":"2014","journal-title":"Lancet (Lond., Engl. )"},{"key":"10.1016\/j.ajp.2024.104090_bib14","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1176\/appi.ajp.20230025","article-title":"Pharmacotherapies for Treatment-Resistant Depression: How Antipsychotics Fit in the Rapidly Evolving Therapeutic Landscape","volume":"180","author":"Jha","year":"2023","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.ajp.2024.104090_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2022.114396","article-title":"A single intravenous administration of a sub-anesthetic ketamine dose during the perioperative period of cesarean section for preventing postpartum depression: A meta-analysis","volume":"310","author":"Li","year":"2022","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.ajp.2024.104090_bib16","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.jad.2024.01.202","article-title":"Effects of ketamine and esketamine on preventing postpartum depression after cesarean delivery: A meta-analysis","volume":"351","author":"Li","year":"2024","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.ajp.2024.104090_bib17","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/j.jad.2023.07.103","article-title":"Effects of perioperative use of esketamine on postpartum depression risk in patients undergoing cesarean section: a randomized controlled trial","volume":"339","author":"Liu","year":"2023","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.ajp.2024.104090_bib18","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.psychres.2019.03.026","article-title":"Prophylactic use of ketamine reduces postpartum depression in Chinese women undergoing cesarean section \u2606","volume":"279","author":"Ma","year":"2019","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.ajp.2024.104090_bib19","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.jad.2020.06.050","article-title":"The effect of intravenous, intranasal, and oral ketamine in mood disorders: A meta-analysis","volume":"276","author":"McIntyre","year":"2020","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.ajp.2024.104090_bib20","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1080\/14740338.2022.2066651","article-title":"Long-term safety of ketamine and esketamine in treatment of depression","volume":"21","author":"Nikayin","year":"2022","journal-title":"Expert Opin. Drug Saf."},{"key":"10.1016\/j.ajp.2024.104090_bib21","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/j.1600-079X.2007.00487.x","article-title":"Pineal melatonin and the innate immune response: the TNF-\u03b1 increase after cesarean section suppresses nocturnal melatonin production","volume":"43","author":"Pontes","year":"2007","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.ajp.2024.104090_bib22","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.psychres.2015.10.032","article-title":"Meta-analysis of short- and mid-term efficacy of ketamine in unipolar and bipolar depression","volume":"230","author":"Romeo","year":"2015","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.ajp.2024.104090_bib23","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1001\/jamapsychiatry.2017.0080","article-title":"A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders","volume":"74","author":"Sanacora","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.ajp.2024.104090_bib24","doi-asserted-by":"crossref","first-page":"1038379","DOI":"10.3389\/fpsyt.2022.1038379","article-title":"The effect of low-dose esketamine on pain and post-partum depression after cesarean section: A prospective, randomized, double-blind clinical trial","volume":"13","author":"Shen","year":"2023","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.ajp.2024.104090_bib25","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/S2215-0366(19)30533-4","article-title":"Approval of esketamine for treatment-resistant depression","volume":"7","author":"Singh","year":"2020","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.ajp.2024.104090_bib26","article-title":"Effect of pre-administration of esketamine intraoperatively on postpartum depression after cesarean section: A randomized, double-blinded controlled trial","volume":"102","author":"Wang","year":"2023","journal-title":"Medicine"},{"key":"10.1016\/j.ajp.2024.104090_bib27","article-title":"Effects of esketamine on analgesia and postpartum depression after cesarean section: a randomized, double-blinded controlled trial","volume":"101","author":"Wang","year":"2022","journal-title":"Medicine"},{"key":"10.1016\/j.ajp.2024.104090_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2021.105761","article-title":"Novel rapid-acting glutamatergic modulators: Targeting the synaptic plasticity in depression","volume":"171","author":"Wang","year":"2021","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.ajp.2024.104090_bib29","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1038\/s41380-021-01121-1","article-title":"Molecular mechanisms underlying the antidepressant actions of arketamine: beyond the NMDA receptor","volume":"27","author":"Wei","year":"2022","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.ajp.2024.104090_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2024.115765","article-title":"Efficacy and safety of perioperative application of esketamine on postpartum depression: A meta-analysis of randomized controlled studies","volume":"333","author":"Wen","year":"2024","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.ajp.2024.104090_bib31","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1007\/s00404-017-4334-8","article-title":"Single bolus low-dose of ketamine does not prevent postpartum depression: a randomized, double-blind, placebo-controlled, prospective clinical trial","volume":"295","author":"Xu","year":"2017","journal-title":"Arch. Gynecol. Obstet."},{"key":"10.1016\/j.ajp.2024.104090_bib32","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.jad.2023.07.007","article-title":"Effects of different doses of esketamine intervention on postpartum depressive symptoms in cesarean section women: A randomized, double-blind, controlled clinical study","volume":"339","author":"Yang","year":"2023","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.ajp.2024.104090_bib33","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.1715","article-title":"Intraoperative ketamine for reduction in postpartum depressive symptoms after cesarean delivery: A double-blind, randomized clinical trial","volume":"10","author":"Yao","year":"2020","journal-title":"Brain Behav."},{"key":"10.1016\/j.ajp.2024.104090_bib34","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1247646","article-title":"Esketamine combined with sufentanil versus sufentanil in patient-controlled intravenous analgesia: a meta-analysis","volume":"15","author":"Yao","year":"2024","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.ajp.2024.104090_bib35","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1001\/archpsyc.63.8.856","article-title":"A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression","volume":"63","author":"Zarate","year":"2006","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.ajp.2024.104090_bib36","doi-asserted-by":"crossref","DOI":"10.1186\/s12910-016-0087-3","article-title":"Is off-label repeat prescription of ketamine as a rapid antidepressant safe? Controversies, ethical concerns, and legal implications","volume":"17","author":"Zhang","year":"2016","journal-title":"BMC Med. Ethics"},{"key":"10.1016\/j.ajp.2024.104090_bib37","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1186\/s12884-021-04229-y","article-title":"Optimum dose of spinal ropivacaine with or without single intravenous bolus of S-ketamine during elective cesarean delivery: a randomized, double-blind, sequential dose-finding study","volume":"21","author":"Zhang","year":"2021","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.ajp.2024.104090_bib38","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/s12264-016-0081-2","article-title":"Risks associated with misuse of ketamine as a rapid-acting antidepressant","volume":"32","author":"Zhu","year":"2016","journal-title":"Neurosci. Bull."}],"container-title":["Asian Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1876201824001837?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1876201824001837?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T17:27:39Z","timestamp":1721237259000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1876201824001837"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":38,"alternative-id":["S1876201824001837"],"URL":"https:\/\/doi.org\/10.1016\/j.ajp.2024.104090","relation":{},"ISSN":["1876-2018"],"issn-type":[{"value":"1876-2018","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy and safety of peri-partum Esketamine for prevention of post-partum depression in women undergoing caesarian section: A meta-analysis and systematic review of randomized controlled trials","name":"articletitle","label":"Article Title"},{"value":"Asian Journal of Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajp.2024.104090","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"104090"}}