{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T21:39:33Z","timestamp":1779917973354,"version":"3.53.1"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Asian Journal of Psychiatry"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.ajp.2025.104624","type":"journal-article","created":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T20:01:40Z","timestamp":1752609700000},"page":"104624","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Cannabis and suicide risk in first-episode psychosis: Mechanisms, interactions, and intervention strategies"],"prefix":"10.1016","volume":"110","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1717-2530","authenticated-orcid":false,"given":"Valerio","family":"Ricci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Sarni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marialuiga","family":"Barresi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Remondino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Martinotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Maina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7374","key":"10.1016\/j.ajp.2025.104624_bib1","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1136\/bmj.325.7374.1212","article-title":"Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study","volume":"325","author":"Arseneault","year":"2002","journal-title":"BMJ"},{"issue":"1-3","key":"10.1016\/j.ajp.2025.104624_bib2","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.schres.2015.01.004","article-title":"The development of insight and its relationship with suicidality over one year follow-up in patients with first episode psychosis","volume":"162","author":"Barrett","year":"2015","journal-title":"Schizophr. Res."},{"issue":"1-3","key":"10.1016\/j.ajp.2025.104624_bib3","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.schres.2010.03.022","article-title":"Suicidality before and in the early phases of first episode psychosis","volume":"119","author":"Barrett","year":"2010","journal-title":"Schizophr. Res."},{"issue":"2","key":"10.1016\/j.ajp.2025.104624_bib4","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.comppsych.2010.06.001","article-title":"Neurocognitive functioning and suicidality in schizophrenia spectrum disorders","volume":"52","author":"Barrett","year":"2011","journal-title":"Compr. Psychiatry"},{"key":"10.1016\/j.ajp.2025.104624_bib5","doi-asserted-by":"crossref","first-page":"c6325","DOI":"10.1136\/bmj.c6325","article-title":"Integrated motivational interviewing and cognitive behavioural therapy for people with psychosis and comorbid substance misuse: randomised controlled trial","volume":"341","author":"Barrowclough","year":"2010","journal-title":"BMJ"},{"issue":"13","key":"10.1016\/j.ajp.2025.104624_bib6","doi-asserted-by":"crossref","first-page":"2568","DOI":"10.1038\/npp.2013.165","article-title":"Peripheral endocannabinoid system dysregulation in first-episode psychosis","volume":"38","author":"Bioque","year":"2013","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.ajp.2025.104624_bib7","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.jad.2016.02.007","article-title":"A literature review and meta-analyses of cannabis use and suicidality","volume":"195","author":"Borges","year":"2016","journal-title":"J. Affect. Disord."},{"issue":"32","key":"10.1016\/j.ajp.2025.104624_bib8","doi-asserted-by":"crossref","first-page":"5093","DOI":"10.2174\/138161212802884672","article-title":"Cannabis use and duration of untreated psychosis: a systematic review and meta-analysis","volume":"18","author":"Burns","year":"2012","journal-title":"Curr. Pharm. Des."},{"issue":"10","key":"10.1016\/j.ajp.2025.104624_bib9","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/j.biopsych.2005.01.026","article-title":"Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction","volume":"57","author":"Caspi","year":"2005","journal-title":"Biol. Psychiatry"},{"issue":"6","key":"10.1016\/j.ajp.2025.104624_bib10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0129263","article-title":"Suicide in recent onset psychosis revisited: significant reduction of suicide rate over the last two decades - a replication study of a Dutch incidence cohort","volume":"10","author":"Castelein","year":"2015","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.ajp.2025.104624_bib11","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s00406-019-00983-5","article-title":"New trends in cannabis potency in USA and Europe during the last decade (2008\u20132017)","volume":"269","author":"Chandra","year":"2019","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"issue":"2","key":"10.1016\/j.ajp.2025.104624_bib12","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s00127-014-0946-5","article-title":"Prevalence and risk factors for suicidal behavior in young people presenting with first-episode psychosis in Hong Kong: a 3-year follow-up study","volume":"50","author":"Chang","year":"2015","journal-title":"Soc. Psychiatry Psychiatr. Epidemiol."},{"issue":"1","key":"10.1016\/j.ajp.2025.104624_bib13","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1017\/S0033291713000433","article-title":"Change in cannabis use, clinical symptoms and social functioning among patients with first-episode psychosis: a 5-year follow-up study of patients in the OPUS trial","volume":"44","author":"Clausen","year":"2014","journal-title":"Psychol. Med."},{"issue":"5","key":"10.1016\/j.ajp.2025.104624_bib14","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1093\/schbul\/sbv032","article-title":"Interaction between functional genetic variation of DRD2 and cannabis use on risk of psychosis","volume":"41","author":"Colizzi","year":"2015","journal-title":"Schizophr. Bull."},{"issue":"32","key":"10.1016\/j.ajp.2025.104624_bib15","doi-asserted-by":"crossref","first-page":"5036","DOI":"10.2174\/138161212802884762","article-title":"Cannabis use in patients at clinical high risk of psychosis: impact on prodromal symptoms and transition to psychosis","volume":"18","author":"van der Meer","year":"2012","journal-title":"Curr. Pharm. Des."},{"issue":"10","key":"10.1016\/j.ajp.2025.104624_bib16","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.biopsych.2012.06.020","article-title":"Confirmation that the AKT1 (rs2494732) genotype influences the risk of psychosis in cannabis users","volume":"72","author":"Di Forti","year":"2012","journal-title":"Biol. Psychiatry"},{"issue":"3","key":"10.1016\/j.ajp.2025.104624_bib17","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S2215-0366(14)00117-5","article-title":"Proportion of patients in south London with first-episode psychosis attributable to use of high potency cannabis: a case-control study","volume":"2","author":"Di Forti","year":"2015","journal-title":"Lancet Psychiatry"},{"issue":"6","key":"10.1016\/j.ajp.2025.104624_bib18","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1192\/bjp.bp.109.064220","article-title":"High-potency cannabis and the risk of psychosis","volume":"195","author":"Di Forti","year":"2009","journal-title":"Br. J. Psychiatry"},{"issue":"5","key":"10.1016\/j.ajp.2025.104624_bib19","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S2215-0366(19)30048-3","article-title":"The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control study","volume":"6","author":"Di Forti","year":"2019","journal-title":"Lancet Psychiatry"},{"issue":"3","key":"10.1016\/j.ajp.2025.104624_bib20","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.psychres.2013.12.038","article-title":"Cannabis use, gender and age of onset of schizophrenia: data from the \u00c6SOP study","volume":"215","author":"Donoghue","year":"2014","journal-title":"Psychiatry Res"},{"issue":"2","key":"10.1016\/j.ajp.2025.104624_bib21","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1600-0447.2006.00783.x","article-title":"Randomized controlled trial of a cannabis-focused intervention for young people with first-episode psychosis","volume":"114","author":"Edwards","year":"2006","journal-title":"Acta Psychiatr. Scand."},{"issue":"7","key":"10.1016\/j.ajp.2025.104624_bib22","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.biopsych.2016.01.004","article-title":"Changes in cannabis potency over the last 2 decades (1995\u20132014): analysis of current data in the United States","volume":"79","author":"ElSohly","year":"2016","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.ajp.2025.104624_bib23","unstructured":"European Monitoring Centre for Drugs and Drug Addiction, 2023. European Drug Report 2023: Trends and Developments. Publications Office of the European Union, Luxembourg."},{"issue":"1-2","key":"10.1016\/j.ajp.2025.104624_bib24","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.psychres.2008.10.006","article-title":"Temporal pattern of suicide risk in young individuals with early psychosis","volume":"175","author":"Fedyszyn","year":"2010","journal-title":"Psychiatry Res"},{"issue":"6","key":"10.1016\/j.ajp.2025.104624_bib25","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1111\/add.14525","article-title":"Increasing potency and price of cannabis in Europe, 2006-16","volume":"114","author":"Freeman","year":"2019","journal-title":"Addiction"},{"issue":"4","key":"10.1016\/j.ajp.2025.104624_bib26","doi-asserted-by":"crossref","first-page":"475","DOI":"10.4088\/JCP.08m04672yel","article-title":"Family outcomes from a randomized control trial of relapse prevention therapy in first-episode psychosis","volume":"71","author":"Gleeson","year":"2010","journal-title":"J. Clin. Psychiatry"},{"issue":"4","key":"10.1016\/j.ajp.2025.104624_bib27","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1001\/jamapsychiatry.2018.4500","article-title":"Association of cannabis use in adolescence and risk of depression, anxiety, and suicidality in young adulthood: a systematic review and meta-analysis","volume":"76","author":"Gobbi","year":"2019","journal-title":"JAMA Psychiatry"},{"issue":"3","key":"10.1016\/j.ajp.2025.104624_bib28","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1093\/schbul\/sbp126","article-title":"Cannabis and first-episode psychosis: different long-term outcomes depending on continued or discontinued use","volume":"37","author":"Gonz\u00e1lez-Pinto","year":"2011","journal-title":"Schizophr. Bull."},{"issue":"2","key":"10.1016\/j.ajp.2025.104624_bib29","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1521-0391.2009.00027.x","article-title":"N-acetylcysteine (NAC) in young marijuana users: an open-label pilot study","volume":"19","author":"Gray","year":"2010","journal-title":"Am. J. Addict."},{"issue":"7650","key":"10.1016\/j.ajp.2025.104624_bib30","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"issue":"1","key":"10.1016\/j.ajp.2025.104624_bib31","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.schres.2015.11.027","article-title":"Cannabis use is associated with 3years earlier onset of schizophrenia spectrum disorder in a naturalistic, multi-site sample (N=1119)","volume":"170","author":"Helle","year":"2016","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.ajp.2025.104624_bib32","doi-asserted-by":"crossref","first-page":"d5928","DOI":"10.1136\/bmj.d5928","article-title":"The Cochrane Collaboration's tool for assessing risk of bias in randomised trials","volume":"343","author":"Higgins","year":"2011","journal-title":"BMJ"},{"issue":"4","key":"10.1016\/j.ajp.2025.104624_bib33","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1176\/appi.ajp.2015.15050632","article-title":"Comprehensive versus usual community care for first-episode psychosis: 2-year outcomes from the NIMH RAISE Early Treatment Program","volume":"173","author":"Kane","year":"2016","journal-title":"Am. J. Psychiatry"},{"issue":"2","key":"10.1016\/j.ajp.2025.104624_bib34","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1080\/09595230410001704127","article-title":"A brief motivational intervention for substance misuse in recent-onset psychosis","volume":"23","author":"Kavanagh","year":"2004","journal-title":"Drug Alcohol Rev."},{"issue":"6","key":"10.1016\/j.ajp.2025.104624_bib35","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1001\/archgenpsychiatry.2011.5","article-title":"Cannabis use and earlier onset of psychosis: a systematic meta-analysis","volume":"68","author":"Large","year":"2011","journal-title":"Arch. Gen. Psychiatry"},{"issue":"1-3","key":"10.1016\/j.ajp.2025.104624_bib36","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.schres.2007.04.025","article-title":"Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: impact of cannabis use","volume":"94","author":"Leweke","year":"2007","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.ajp.2025.104624_bib37","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.psychres.2017.01.045","article-title":"Cannabis use, COMT, BDNF and age at first-episode psychosis","volume":"250","author":"Man\u00e9","year":"2017","journal-title":"Psychiatry Res"},{"issue":"5","key":"10.1016\/j.ajp.2025.104624_bib38","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1093\/schbul\/sbw003","article-title":"Meta-analysis of the association between the level of cannabis use and risk of psychosis","volume":"42","author":"Marconi","year":"2016","journal-title":"Schizophr. Bull."},{"issue":"3","key":"10.1016\/j.ajp.2025.104624_bib39","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1176\/appi.ajp.2017.17030325","article-title":"Cannabidiol (CBD) as an adjunctive therapy in schizophrenia: a multicenter randomized controlled trial","volume":"175","author":"McGuire","year":"2018","journal-title":"Am. J. Psychiatry"},{"issue":"2","key":"10.1016\/j.ajp.2025.104624_bib40","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1080\/13811111003704787","article-title":"Course and predictors of suicidality over the first two years of treatment in first-episode schizophrenia spectrum psychosis","volume":"14","author":"Melle","year":"2010","journal-title":"Arch. Suicide Res."},{"issue":"5","key":"10.1016\/j.ajp.2025.104624_bib41","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1192\/bjp.168.5.612","article-title":"Drug and alcohol problems among individuals with severe mental illness in south London","volume":"168","author":"Menezes","year":"1996","journal-title":"Br. J. Psychiatry"},{"issue":"2-3","key":"10.1016\/j.ajp.2025.104624_bib42","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.schres.2009.04.018","article-title":"A prospective study of cannabis use as a risk factor for non-adherence and treatment dropout in first-episode schizophrenia","volume":"113","author":"Miller","year":"2009","journal-title":"Schizophr. Res."},{"issue":"9","key":"10.1016\/j.ajp.2025.104624_bib43","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1016\/j.addbeh.2013.03.011","article-title":"Cannabidiol reduces cigarette consumption in tobacco smokers: preliminary findings","volume":"38","author":"Morgan","year":"2013","journal-title":"Addict. Behav."},{"issue":"2","key":"10.1016\/j.ajp.2025.104624_bib44","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2015.219","article-title":"AKT1 genotype moderates the acute psychotomimetic effects of naturalistically smoked cannabis in young cannabis smokers","volume":"6","author":"Morgan","year":"2016","journal-title":"Transl. Psychiatry"},{"issue":"3","key":"10.1016\/j.ajp.2025.104624_bib45","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1177\/0004867415599846","article-title":"Cannabis use in first episode psychosis: meta-analysis of prevalence, and the time course of initiation and continued use","volume":"50","author":"Myles","year":"2016","journal-title":"Aust. NZ. J. Psychiatry"},{"key":"10.1016\/j.ajp.2025.104624_bib46","first-page":"s120","article-title":"OPUS study: suicidal behaviour, suicidal ideation and hopelessness among patients with first-episode psychosis. One-year follow-up of a randomised controlled trial","volume":"43","author":"Nordentoft","year":"2002","journal-title":"Br. J. Psychiatry Suppl."},{"issue":"16","key":"10.1016\/j.ajp.2025.104624_bib47","first-page":"3497","article-title":"Suicidal behavior in a national cohort of first-episode psychosis patients","volume":"45","author":"Nordentoft","year":"2015","journal-title":"Psychol. Med."},{"issue":"1","key":"10.1016\/j.ajp.2025.104624_bib48","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/eip.12542","article-title":"The impact of tobacco, alcohol, and cannabis use in patients with first-episode psychosis: data from the national RAISE-ETP study","volume":"13","author":"Oluwoye","year":"2019","journal-title":"Early Interv. Psychiatry"},{"issue":"7","key":"10.1016\/j.ajp.2025.104624_bib49","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1111\/add.13788","volume":"112","author":"\u00d8stergaard","year":"2017","journal-title":"Addiction"},{"key":"10.1016\/j.ajp.2025.104624_bib50","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"issue":"3","key":"10.1016\/j.ajp.2025.104624_bib51","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2015-009888","article-title":"Association of cannabis use with hospital admission and antipsychotic treatment failure in first episode psychosis: an observational study","volume":"6","author":"Patel","year":"2016","journal-title":"BMJ Open"},{"issue":"4","key":"10.1016\/j.ajp.2025.104624_bib52","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1046\/j.1440-1614.2003.01209.x","article-title":"Suicide prevention in first episode psychosis: the development of a randomised controlled trial of cognitive therapy for acutely suicidal patients with early psychosis","volume":"37","author":"Power","year":"2003","journal-title":"Aust. N. Z. J. Psychiatry"},{"issue":"Pt A","key":"10.1016\/j.ajp.2025.104624_bib53","article-title":"Cannabis use disorder and dissociation: a report from a prospective first-episode psychosis study","volume":"229","author":"Ricci","year":"2021","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.ajp.2025.104624_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2023.115053","article-title":"First episode psychosis with and without the use of cannabis and synthetic cannabinoids: psychopathology, global functioning and suicidal ideation and antipsychotic effectiveness","volume":"320","author":"Ricci","year":"2023","journal-title":"Psychiatry Res"},{"issue":"3","key":"10.1016\/j.ajp.2025.104624_bib55","doi-asserted-by":"crossref","first-page":"307","DOI":"10.24869\/psyd.2023.307","article-title":"Cannabis use and suicide in non-affective psychosis: a mini-review of recent literature","volume":"35","author":"Ricci","year":"2023","journal-title":"Psychiatr. Danub"},{"issue":"23","key":"10.1016\/j.ajp.2025.104624_bib56","doi-asserted-by":"crossref","first-page":"12632","DOI":"10.3390\/ijerph182312632","article-title":"Duration of untreated disorder and cannabis use: an observational study on a cohort of young italian patients experiencing psychotic experiences and dissociative symptoms","volume":"18","author":"Ricci","year":"2021","journal-title":"Int. J. Environ. Res. Public Health"},{"issue":"2","key":"10.1016\/j.ajp.2025.104624_bib57","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1600-0447.2007.01135.x","article-title":"Illicit drug use in patients with psychotic disorders compared with that in the general population: a cross-sectional study","volume":"117","author":"Ringen","year":"2008","journal-title":"Acta Psychiatr. Scand."},{"issue":"2","key":"10.1016\/j.ajp.2025.104624_bib58","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1080\/00048670802607162","article-title":"Prevalence and predictors of suicide attempt in an incidence cohort of 661 young people with first-episode psychosis","volume":"43","author":"Robinson","year":"2009","journal-title":"Aust. NZ. J. Psychiatry"},{"issue":"3","key":"10.1016\/j.ajp.2025.104624_bib59","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S2215-0366(15)00363-6","article-title":"Continued versus discontinued cannabis use in patients with psychosis: a systematic review and meta-analysis","volume":"3","author":"Schoeler","year":"2016","journal-title":"Lancet Psychiatry"},{"issue":"8","key":"10.1016\/j.ajp.2025.104624_bib60","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1017\/S0033291715003001","article-title":"Continuity of cannabis use and violent offending over the life course","volume":"46","author":"Schoeler","year":"2016","journal-title":"Psychol. Med."},{"issue":"3","key":"10.1016\/j.ajp.2025.104624_bib61","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1093\/schbul\/sbv154","article-title":"Cannabis use is associated with increased psychotic symptoms and poorer psychosocial functioning in first-episode psychosis: a report from the UK National EDEN Study","volume":"42","author":"Seddon","year":"2016","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.ajp.2025.104624_bib62","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.schres.2018.05.036","article-title":"Age of onset of cannabis use and cognitive function in first-episode non-affective psychosis patients: outcome at three-year follow-up","volume":"201","author":"Seti\u00e9n-Suero","year":"2018","journal-title":"Schizophr. Res."},{"issue":"5","key":"10.1016\/j.ajp.2025.104624_bib63","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1111\/j.1600-0447.2001.00452.x","article-title":"Correlates of substance misuse in patients with first-episode schizophrenia and schizoaffective disorder","volume":"104","author":"Sevy","year":"2001","journal-title":"Acta Psychiatr. Scand."},{"issue":"1-3","key":"10.1016\/j.ajp.2025.104624_bib64","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.schres.2010.03.037","article-title":"Are cannabis use disorders associated with an earlier age at onset of psychosis? A study in first episode schizophrenia","volume":"120","author":"Sevy","year":"2010","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.ajp.2025.104624_bib65","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.jad.2016.07.010","article-title":"The association between cannabis use and suicidality among men and women: a population-based longitudinal study","volume":"205","author":"Shalit","year":"2016","journal-title":"J. Affect. Disord."},{"issue":"10","key":"10.1016\/j.ajp.2025.104624_bib66","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1111\/j.1360-0443.2004.00806.x","article-title":"Early adolescent cannabis exposure and positive and negative dimensions of psychosis","volume":"99","author":"Stefanis","year":"2004","journal-title":"Addiction"},{"issue":"3","key":"10.1016\/j.ajp.2025.104624_bib67","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1017\/S0033291713000883","article-title":"Cannabis use and first-episode psychosis: relationship with manic and psychotic symptoms, and with age at presentation","volume":"44","author":"Stone","year":"2014","journal-title":"Psychol. Med."},{"key":"10.1016\/j.ajp.2025.104624_bib68","unstructured":"Substance Abuse and Mental Health Services Administration, 2022. Key substance use and mental health indicators in the United States: Results from the 2021 National Survey on Drug Use and Health. Center for Behavioral Health Statistics and Quality, Rockville, MD."},{"issue":"1","key":"10.1016\/j.ajp.2025.104624_bib69","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s00127-006-0127-2","article-title":"The subjective consequences of suffering a first episode psychosis: trauma and suicide behaviour","volume":"42","author":"Tarrier","year":"2007","journal-title":"Soc. Psychiatry Psychiatr. Epidemiol."},{"key":"10.1016\/j.ajp.2025.104624_bib70","unstructured":"United Nations Office on Drugs and Crime, 2023. World Drug Report 2023. United Nations Publication, Vienna."},{"issue":"1-2","key":"10.1016\/j.ajp.2025.104624_bib71","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.schres.2015.07.050","article-title":"Social defeat predicts paranoid appraisals in people at high risk for psychosis","volume":"168","author":"Valmaggia","year":"2015","journal-title":"Schizophr. Res."},{"issue":"12","key":"10.1016\/j.ajp.2025.104624_bib72","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1017\/S0033291714000117","article-title":"Cannabis use and transition to psychosis in people at ultra-high risk","volume":"44","author":"Valmaggia","year":"2014","journal-title":"Psychol. Med."},{"issue":"8","key":"10.1016\/j.ajp.2025.104624_bib73","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1177\/0004867412450471","article-title":"Medication for psychosis-consumption and consequences: the second Australian national survey of psychosis","volume":"46","author":"Waterreus","year":"2012","journal-title":"Aust. NZ J. Psychiatry"}],"container-title":["Asian Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1876201825002679?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1876201825002679?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T08:10:58Z","timestamp":1767773458000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1876201825002679"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":73,"alternative-id":["S1876201825002679"],"URL":"https:\/\/doi.org\/10.1016\/j.ajp.2025.104624","relation":{},"ISSN":["1876-2018"],"issn-type":[{"value":"1876-2018","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cannabis and suicide risk in first-episode psychosis: Mechanisms, interactions, and intervention strategies","name":"articletitle","label":"Article Title"},{"value":"Asian Journal of Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajp.2025.104624","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"104624"}}