{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:35:10Z","timestamp":1787315710219,"version":"build-2736575974"},"reference-count":57,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,22]],"date-time":"2013-07-22T00:00:00Z","timestamp":1374451200000},"content-version":"vor","delay-in-days":416,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000901","name":"Juvenile Diabetes Research Foundation International","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000901","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["EY018138"],"award-info":[{"award-number":["EY018138"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajp.amjpathol.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Pathology"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1016\/j.ajpath.2012.02.021","type":"journal-article","created":{"date-parts":[[2012,4,19]],"date-time":"2012-04-19T03:50:43Z","timestamp":1334807443000},"page":"2548-2560","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"title":["MEF2C Ablation in Endothelial Cells Reduces Retinal Vessel Loss and Suppresses Pathologic Retinal Neovascularization in Oxygen-Induced Retinopathy"],"prefix":"10.1016","volume":"180","author":[{"given":"Zhenhua","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junsong","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debasish","family":"Maiti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linh","family":"Vong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijuan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"Schwarz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elia J.","family":"Duh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajpath.2012.02.021_bib1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s10633-009-9181-x","article-title":"The effects of oxygen stresses on the development of features of severe retinopathy of prematurity: knowledge from the 50\/10 OIR model","volume":"120","author":"Hartnett","year":"2010","journal-title":"Doc Ophthalmol"},{"key":"10.1016\/j.ajpath.2012.02.021_bib2","doi-asserted-by":"crossref","first-page":"3022","DOI":"10.1172\/JCI42142","article-title":"Retinopathy of prematurity: understanding ischemic retinal vasculopathies at an extreme of life","volume":"120","author":"Sapieha","year":"2010","journal-title":"J Clin Invest"},{"key":"10.1016\/j.ajpath.2012.02.021_bib3","doi-asserted-by":"crossref","first-page":"5177","DOI":"10.1167\/iovs.08-2584","article-title":"Through the eyes of a child: understanding retinopathy through ROP the Friedenwald lecture","volume":"49","author":"Smith","year":"2008","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ajpath.2012.02.021_bib4","doi-asserted-by":"crossref","first-page":"d1030","DOI":"10.2741\/1056","article-title":"Animal models of oxygen-induced retinopathy","volume":"8","author":"Madan","year":"2003","journal-title":"Front Biosci"},{"key":"10.1016\/j.ajpath.2012.02.021_bib5","first-page":"101","article-title":"Oxygen-induced retinopathy in the mouse","volume":"35","author":"Smith","year":"1994","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ajpath.2012.02.021_bib6","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1167\/iovs.10-5176","article-title":"The mouse retina as an angiogenesis model","volume":"51","author":"Stahl","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ajpath.2012.02.021_bib7","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s10633-009-9201-x","article-title":"Understanding ischemic retinopathies: emerging concepts from oxygen-induced retinopathy","volume":"120","author":"Kermorvant-Duchemin","year":"2009","journal-title":"Doc Ophthalmol"},{"key":"10.1016\/j.ajpath.2012.02.021_bib8","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1006\/dbio.1999.9307","article-title":"The transcription factor MEF2C-null mouse exhibits complex vascular malformations and reduced cardiac expression of angiopoietin 1 and VEGF","volume":"211","author":"Bi","year":"1999","journal-title":"Dev Biol"},{"key":"10.1016\/j.ajpath.2012.02.021_bib9","doi-asserted-by":"crossref","first-page":"4565","DOI":"10.1242\/dev.125.22.4565","article-title":"Requirement of the MADS-box transcription factor MEF2C for vascular development","volume":"125","author":"Lin","year":"1998","journal-title":"Development"},{"key":"10.1016\/j.ajpath.2012.02.021_bib10","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1126\/science.276.5317.1404","article-title":"Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C","volume":"276","author":"Lin","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.ajpath.2012.02.021_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1432-1033.1995.tb20430.x","article-title":"The MADS-box family of transcription factors","volume":"229","author":"Shore","year":"1995","journal-title":"Eur J Biochem"},{"key":"10.1016\/j.ajpath.2012.02.021_bib12","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1006\/dbio.1995.0002","article-title":"Regulation of muscle differentiation by the MEF2 family of MADS box transcription factors","volume":"172","author":"Olson","year":"1995","journal-title":"Dev Biol"},{"key":"10.1016\/j.ajpath.2012.02.021_bib13","doi-asserted-by":"crossref","first-page":"4131","DOI":"10.1242\/dev.008367","article-title":"MEF2: a central regulator of diverse developmental programs","volume":"134","author":"Potthoff","year":"2007","journal-title":"Development"},{"key":"10.1016\/j.ajpath.2012.02.021_bib14","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1006\/bbrc.2001.5589","article-title":"SOX18 directly interacts with MEF2C in endothelial cells","volume":"287","author":"Hosking","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.ajpath.2012.02.021_bib15","doi-asserted-by":"crossref","first-page":"3640","DOI":"10.1167\/iovs.08-1760","article-title":"Vascular endothelial growth factor induces MEF2C and MEF2-dependent activity in endothelial cells","volume":"49","author":"Maiti","year":"2008","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ajpath.2012.02.021_bib16","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1084\/jem.193.6.741","article-title":"Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrow","volume":"193","author":"Koni","year":"2001","journal-title":"J Exp Med"},{"key":"10.1016\/j.ajpath.2012.02.021_bib17","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/gene.20152","article-title":"Generation of conditional Mef2cloxP\/loxP mice for temporal- and tissue-specific analyses","volume":"43","author":"Vong","year":"2005","journal-title":"Genesis"},{"key":"10.1016\/j.ajpath.2012.02.021_bib18","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1002\/dvdy.20828","article-title":"MEF2C is required for the normal allocation of cells between the ventricular and sinoatrial precursors of the primary heart field","volume":"235","author":"Vong","year":"2006","journal-title":"Dev Dyn"},{"key":"10.1016\/j.ajpath.2012.02.021_bib19","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/5007","article-title":"Generalized lacZ expression with the ROSA26 Cre reporter strain","volume":"21","author":"Soriano","year":"1999","journal-title":"Nat Genet"},{"key":"10.1016\/j.ajpath.2012.02.021_bib20","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1038\/nprot.2009.187","article-title":"Quantification of oxygen-induced retinopathy in the mouse: a model of vessel loss, vessel regrowth and pathological angiogenesis","volume":"4","author":"Connor","year":"2009","journal-title":"Nat Protoc"},{"key":"10.1016\/j.ajpath.2012.02.021_bib21","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1002\/dvdy.1200","article-title":"NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis","volume":"222","author":"Ozerdem","year":"2001","journal-title":"Dev Dyn"},{"key":"10.1016\/j.ajpath.2012.02.021_bib22","first-page":"2462","article-title":"Quantitative assessment of the integrity of the blood-retinal barrier in mice","volume":"43","author":"Derevjanik","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ajpath.2012.02.021_bib23","doi-asserted-by":"crossref","first-page":"7565","DOI":"10.1167\/iovs.11-8002","article-title":"Reduced retinal neovascularization, vascular permeability, and apoptosis in ischemic retinopathy in the absence of prolyl hydroxylase-1 due to the prevention of hyperoxia-induced vascular obliteration","volume":"52","author":"Huang","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ajpath.2012.02.021_bib24","doi-asserted-by":"crossref","first-page":"3488","DOI":"10.1091\/mbc.e04-11-1029","article-title":"Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells","volume":"16","author":"Im","year":"2005","journal-title":"Mol Biol Cell"},{"key":"10.1016\/j.ajpath.2012.02.021_bib25","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1038\/sj.emboj.7601100","article-title":"Regulating angiogenesis at the level of PtdIns-4,5-P2","volume":"25","author":"Im","year":"2006","journal-title":"EMBO J"},{"key":"10.1016\/j.ajpath.2012.02.021_bib26","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1128\/MCB.01275-09","article-title":"Phospholipase C\u03b3 activation drives increased production of autotaxin in endothelial cells and lysophosphatidic acid-dependent regression","volume":"30","author":"Im","year":"2010","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.ajpath.2012.02.021_bib27","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1016\/S0002-9440(10)63741-8","article-title":"Transcription factor Ets-1 mediates ischemia- and vascular endothelial growth factor-dependent retinal neovascularization","volume":"164","author":"Watanabe","year":"2004","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ajpath.2012.02.021_bib28","doi-asserted-by":"crossref","first-page":"2819","DOI":"10.1161\/01.ATV.0000248731.55781.87","article-title":"Tissue factor pathway inhibitor-2 is upregulated by vascular endothelial growth factor and suppresses growth factor-induced proliferation of endothelial cells","volume":"26","author":"Xu","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.ajpath.2012.02.021_bib29","doi-asserted-by":"crossref","first-page":"9152","DOI":"10.1074\/jbc.M510217200","article-title":"Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice","volume":"281","author":"Xu","year":"2006","journal-title":"J Biol Chem"},{"key":"10.1016\/j.ajpath.2012.02.021_bib30","doi-asserted-by":"crossref","first-page":"17067","DOI":"10.1073\/pnas.0804868105","article-title":"A p38 MAPK-MEF2C pathway regulates B-cell proliferation","volume":"105","author":"Khiem","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ajpath.2012.02.021_bib31","doi-asserted-by":"crossref","first-page":"9397","DOI":"10.1073\/pnas.0802876105","article-title":"Transcription factor MEF2C influences neural stem\/progenitor cell differentiation and maturation in vivo","volume":"105","author":"Li","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ajpath.2012.02.021_bib32","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.devcel.2007.03.007","article-title":"The transcription factor MEF2C is required for craniofacial development","volume":"12","author":"Verzi","year":"2007","journal-title":"Dev Cell"},{"key":"10.1016\/j.ajpath.2012.02.021_bib33","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/ni.1609","article-title":"Transcription factor Mef2c is required for B cell proliferation and survival after antigen receptor stimulation","volume":"9","author":"Wilker","year":"2008","journal-title":"Nat Immunol"},{"key":"10.1016\/j.ajpath.2012.02.021_bib34","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/dvg.20367","article-title":"Efficient, inducible Cre-recombinase activation in vascular endothelium","volume":"46","author":"Claxton","year":"2008","journal-title":"Genesis"},{"key":"10.1016\/j.ajpath.2012.02.021_bib35","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1038\/nm1591","article-title":"Increased dietary intake of omega-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis","volume":"13","author":"Connor","year":"2007","journal-title":"Nat Med"},{"key":"10.1016\/j.ajpath.2012.02.021_bib36","doi-asserted-by":"crossref","first-page":"6024","DOI":"10.1182\/blood-2010-10-311589","article-title":"Ischemic neurons prevent vascular regeneration of neural tissue by secreting semaphorin 3A","volume":"117","author":"Joyal","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.ajpath.2012.02.021_bib37","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1007\/s00417-009-1116-4","article-title":"Kinetics of retinal vaso-obliteration and neovascularisation in the oxygen-induced retinopathy (OIR) mouse model","volume":"247","author":"Lange","year":"2009","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.ajpath.2012.02.021_bib38","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1038\/nm1095-1024","article-title":"Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity","volume":"1","author":"Alon","year":"1995","journal-title":"Nat Med"},{"key":"10.1016\/j.ajpath.2012.02.021_bib39","doi-asserted-by":"crossref","first-page":"5933","DOI":"10.1167\/iovs.10-6978","article-title":"Altered expression of the transcription factor Mef2c during retinal degeneration in Rpe65\u2212\/\u2212 mice","volume":"52","author":"Escher","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ajpath.2012.02.021_bib40","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1016\/j.ajpath.2010.12.031","article-title":"Novel protective properties of IGFBP-3 result in enhanced pericyte ensheathment, reduced microglial activation, increased microglial apoptosis, and neuronal protection after ischemic retinal injury","volume":"178","author":"Kielczewski","year":"2011","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ajpath.2012.02.021_bib41","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1097\/MOL.0b013e32830d81e9","article-title":"Effect of heme oxygenase-1 on vascular function and disease","volume":"19","author":"Dulak","year":"2008","journal-title":"Curr Opin Lipidol"},{"key":"10.1016\/j.ajpath.2012.02.021_bib42","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1161\/CIRCULATIONAHA.107.698316","article-title":"Heme oxygenase-1 and carbon monoxide in vascular pathobiology: focus on angiogenesis","volume":"117","author":"Dulak","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.ajpath.2012.02.021_bib43","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1172\/JCI4165","article-title":"Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency","volume":"103","author":"Yachie","year":"1999","journal-title":"J Clin Invest"},{"key":"10.1016\/j.ajpath.2012.02.021_bib44","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1002\/gene.1030","article-title":"Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line","volume":"30","author":"Constien","year":"2001","journal-title":"Genesis"},{"key":"10.1016\/j.ajpath.2012.02.021_bib45","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1161\/CIRCRESAHA.109.199059","article-title":"Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation","volume":"105","author":"Kielczewski","year":"2009","journal-title":"Circ Res"},{"key":"10.1016\/j.ajpath.2012.02.021_bib46","doi-asserted-by":"crossref","first-page":"10589","DOI":"10.1073\/pnas.0702031104","article-title":"IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth","volume":"104","author":"Lofqvist","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ajpath.2012.02.021_bib47","first-page":"526","article-title":"Erythropoietin deficiency decreases vascular stability in mice","volume":"118","author":"Chen","year":"2008","journal-title":"J Clin Invest"},{"key":"10.1016\/j.ajpath.2012.02.021_bib48","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1523\/JNEUROSCI.3210-09.2010","article-title":"Norrin promotes vascular regrowth after oxygen-induced retinal vessel loss and suppresses retinopathy in mice","volume":"30","author":"Ohlmann","year":"2010","journal-title":"J Neurosci"},{"key":"10.1016\/j.ajpath.2012.02.021_bib49","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1002\/dvdy.10412","article-title":"Thrombospondin-1-deficient mice exhibit increased vascular density during retinal vascular development and are less sensitive to hyperoxia-mediated vessel obliteration","volume":"228","author":"Wang","year":"2003","journal-title":"Dev Dyn"},{"key":"10.1016\/j.ajpath.2012.02.021_bib50","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/S0002-9440(10)62284-5","article-title":"Inhibition of tumor necrosis factor-\u03b1 improves physiological angiogenesis and reduces pathological neovascularization in ischemic retinopathy","volume":"166","author":"Gardiner","year":"2005","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ajpath.2012.02.021_bib51","first-page":"840","article-title":"Inhibition of NAD(P)H oxidase reduces apoptosis and avascular retina in an animal model of retinopathy of prematurity","volume":"13","author":"Saito","year":"2007","journal-title":"Mol Vis"},{"key":"10.1016\/j.ajpath.2012.02.021_bib52","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1167\/iovs.07-1356","article-title":"Activated NAD(P)H oxidase from supplemental oxygen induces neovascularization independent of VEGF in retinopathy of prematurity model","volume":"49","author":"Saito","year":"2008","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ajpath.2012.02.021_bib53","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/S0002-9440(10)63001-5","article-title":"Inhibition of NAD(P)H oxidase activity blocks vascular endothelial growth factor overexpression and neovascularization during ischemic retinopathy","volume":"167","author":"Al-Shabrawey","year":"2005","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ajpath.2012.02.021_bib54","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1016\/j.freeradbiomed.2004.09.008","article-title":"Redox-dependent effects of nitric oxide on microvascular integrity in oxygen-induced retinopathy","volume":"37","author":"Beauchamp","year":"2004","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.ajpath.2012.02.021_bib55","first-page":"222","article-title":"Reduced severity of oxygen-induced retinopathy in eNOS-deficient mice","volume":"42","author":"Brooks","year":"2001","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ajpath.2012.02.021_bib56","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1038\/nm1336","article-title":"Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration","volume":"11","author":"Kermorvant-Duchemin","year":"2005","journal-title":"Nat Med"},{"key":"10.1016\/j.ajpath.2012.02.021_bib57","doi-asserted-by":"crossref","first-page":"5785","DOI":"10.1182\/blood-2011-03-343228","article-title":"Sema 3A resists retinal revascularization","volume":"117","author":"Duh","year":"2011","journal-title":"Blood"}],"container-title":["The American Journal of Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944012002441?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944012002441?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T14:39:58Z","timestamp":1757601598000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002944012002441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":57,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["S0002944012002441"],"URL":"https:\/\/doi.org\/10.1016\/j.ajpath.2012.02.021","relation":{},"ISSN":["0002-9440"],"issn-type":[{"value":"0002-9440","type":"print"}],"subject":[],"published":{"date-parts":[[2012,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MEF2C Ablation in Endothelial Cells Reduces Retinal Vessel Loss and Suppresses Pathologic Retinal Neovascularization in Oxygen-Induced Retinopathy","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajpath.2012.02.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 American Society for Investigative Pathology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}