{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:32:30Z","timestamp":1786984350325,"version":"build-2736575974"},"reference-count":69,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,4,21]],"date-time":"2015-04-21T00:00:00Z","timestamp":1429574400000},"content-version":"vor","delay-in-days":355,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The American Journal of Pathology"],"published-print":{"date-parts":[[2014,5]]},"DOI":"10.1016\/j.ajpath.2014.01.021","type":"journal-article","created":{"date-parts":[[2014,3,11]],"date-time":"2014-03-11T20:00:40Z","timestamp":1394568040000},"page":"1577-1592","source":"Crossref","is-referenced-by-count":53,"title":["Preferential Lymphatic Growth in Bronchus-Associated Lymphoid Tissue in Sustained Lung Inflammation"],"prefix":"10.1016","volume":"184","author":[{"given":"Peter","family":"Baluk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Adams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keeley","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Kwon","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary B.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald M.","family":"McDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajpath.2014.01.021_bib1","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1196\/annals.1413.017","article-title":"Lymphatics in lung disease","volume":"1131","author":"El-Chemaly","year":"2008","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.ajpath.2014.01.021_bib2","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.pathophys.2009.10.008","article-title":"Lung lymphatic anatomy and correlates","volume":"17","author":"Schraufnagel","year":"2010","journal-title":"Pathophysiology"},{"key":"10.1016\/j.ajpath.2014.01.021_bib3","doi-asserted-by":"crossref","first-page":"165","DOI":"10.2332\/allergolint.O-07-497","article-title":"Remodeling of airway walls in fatal asthmatics decreases lymphatic distribution: beyond thickening of airway smooth muscle layers","volume":"57","author":"Ebina","year":"2008","journal-title":"Allergol Int"},{"key":"10.1016\/j.ajpath.2014.01.021_bib4","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1016\/j.humpath.2008.01.002","article-title":"Organizing pneumonia and pulmonary lymphatic architecture in diffuse alveolar damage","volume":"39","author":"Mandal","year":"2008","journal-title":"Hum Pathol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib5","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1136\/thoraxjnl-2012-202879","article-title":"Appearance of remodelled and dendritic cell-rich alveolar-lymphoid interfaces provides a structural basis for increased alveolar antigen uptake in chronic obstructive pulmonary disease","volume":"68","author":"Mori","year":"2013","journal-title":"Thorax"},{"key":"10.1016\/j.ajpath.2014.01.021_bib6","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/1465-9921-14-65","article-title":"Increased number and altered phenotype of lymphatic vessels in peripheral lung compartments of patients with COPD","volume":"14","author":"Mori","year":"2013","journal-title":"Respir Res"},{"key":"10.1016\/j.ajpath.2014.01.021_bib7","doi-asserted-by":"crossref","first-page":"3958","DOI":"10.1073\/pnas.0813368106","article-title":"Abnormal lymphangiogenesis in idiopathic pulmonary fibrosis with insights into cellular and molecular mechanisms","volume":"106","author":"El-Chemaly","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ajpath.2014.01.021_bib8","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.humpath.2008.06.031","article-title":"Characterization of lymphangiogenesis in various stages of idiopathic diffuse alveolar damage","volume":"40","author":"Yamashita","year":"2009","journal-title":"Hum Pathol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib9","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1089\/lrb.2010.0008","article-title":"The disappearance of subpleural and interlobular lymphatics in idiopathic pulmonary fibrosis","volume":"8","author":"Ebina","year":"2010","journal-title":"Lymphat Res Biol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib10","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1289\/ehp.803555","article-title":"Lymphatic removal of fluids and particles in the mammalian lung","volume":"35","author":"Leak","year":"1980","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.ajpath.2014.01.021_bib11","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/nri1670","article-title":"Dendritic-cell trafficking to lymph nodes through lymphatic vessels","volume":"5","author":"Randolph","year":"2005","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib12","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1084\/jem.20112667","article-title":"Spatiotemporally separated antigen uptake by alveolar dendritic cells and airway presentation to T cells in the lung","volume":"209","author":"Thornton","year":"2012","journal-title":"J Exp Med"},{"key":"10.1016\/j.ajpath.2014.01.021_bib13","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1182\/blood-2003-08-2964","article-title":"Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia","volume":"104","author":"Kunstfeld","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.ajpath.2014.01.021_bib14","doi-asserted-by":"crossref","first-page":"R118","DOI":"10.1186\/ar2326","article-title":"Increased lymphangiogenesis in joints of mice with inflammatory arthritis","volume":"9","author":"Zhang","year":"2007","journal-title":"Arthritis Res Ther"},{"issue":"Suppl 1","key":"10.1016\/j.ajpath.2014.01.021_bib15","doi-asserted-by":"crossref","first-page":"E75","DOI":"10.1111\/j.1749-6632.2010.05757.x","article-title":"Emerging roles of lymphatics in inflammatory bowel disease","volume":"1207","author":"Alexander","year":"2010","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.ajpath.2014.01.021_bib16","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1084\/jem.20100559","article-title":"Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation","volume":"207","author":"Huggenberger","year":"2010","journal-title":"J Exp Med"},{"key":"10.1016\/j.ajpath.2014.01.021_bib17","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1172\/JCI200522037","article-title":"Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation","volume":"115","author":"Baluk","year":"2005","journal-title":"J Clin Invest"},{"key":"10.1016\/j.ajpath.2014.01.021_bib18","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.2353\/ajpath.2010.090909","article-title":"Steroid-resistant lymphatic remodeling in chronically inflamed mouse airways","volume":"176","author":"Yao","year":"2010","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib19","doi-asserted-by":"crossref","first-page":"e55201","DOI":"10.1371\/journal.pone.0055201","article-title":"Visualization of intrapulmonary lymph vessels in healthy and inflamed murine lung using CD90\/Thy-1 as a marker","volume":"8","author":"Kretschmer","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.ajpath.2014.01.021_bib20","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.cell.2010.01.045","article-title":"Lymphangiogenesis: molecular mechanisms and future promise","volume":"140","author":"Tammela","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.ajpath.2014.01.021_bib21","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1093\/jnci\/dji003","article-title":"Complete and specific inhibition of adult lymphatic regeneration by a novel VEGFR-3 neutralizing antibody","volume":"97","author":"Pytowski","year":"2005","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ajpath.2014.01.021_bib22","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s00417-007-0683-5","article-title":"Blockade of VEGFR3-signalling specifically inhibits lymphangiogenesis in inflammatory corneal neovascularisation","volume":"246","author":"Bock","year":"2008","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib23","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1096\/fj.06-6656com","article-title":"Cooperative and redundant roles of VEGFR-2 and VEGFR-3 signaling in adult lymphangiogenesis","volume":"21","author":"Goldman","year":"2007","journal-title":"FASEB J"},{"key":"10.1016\/j.ajpath.2014.01.021_bib24","doi-asserted-by":"crossref","first-page":"2666","DOI":"10.1002\/art.24764","article-title":"Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis","volume":"60","author":"Guo","year":"2009","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.ajpath.2014.01.021_bib25","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.immuni.2006.01.003","article-title":"B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization","volume":"24","author":"Angeli","year":"2006","journal-title":"Immunity"},{"key":"10.1016\/j.ajpath.2014.01.021_bib26","doi-asserted-by":"crossref","first-page":"2650","DOI":"10.1158\/0008-5472.CAN-05-1843","article-title":"Inhibition of VEGFR-3 activation with the antagonistic antibody more potently suppresses lymph node and distant metastases than inactivation of VEGFR-2","volume":"66","author":"Roberts","year":"2006","journal-title":"Cancer Res"},{"key":"10.1016\/j.ajpath.2014.01.021_bib27","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1182\/blood-2010-07-298562","article-title":"Visualization of lymphatic vessels by Prox1-promoter directed GFP reporter in a bacterial artificial chromosome-based transgenic mouse","volume":"117","author":"Choi","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.ajpath.2014.01.021_bib28","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/S0002-9440(10)63369-X","article-title":"Regulated angiogenesis and vascular regression in mice overexpressing vascular endothelial growth factor in airways","volume":"165","author":"Baluk","year":"2004","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib29","first-page":"63","article-title":"Experimental Mycoplasma pulmonis infection in pathogen-free mice: models for studying mycoplasmosis of the respiratory tract","volume":"72","author":"Lindsey","year":"1973","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib30","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/j.0105-2896.2005.00299.x","article-title":"Bronchus- and nasal-associated lymphoid tissues","volume":"206","author":"Bienenstock","year":"2005","journal-title":"Immunol Rev"},{"key":"10.1016\/j.ajpath.2014.01.021_bib31","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1165\/rcmb.2010-0152RT","article-title":"Bronchus-associated lymphoid tissue: an entry site for antigens for successful mucosal vaccinations?","volume":"43","author":"Pabst","year":"2010","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib32","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/B978-0-12-381300-8.00007-1","article-title":"Bronchus-associated lymphoid tissue (BALT) structure and function","volume":"107","author":"Randall","year":"2010","journal-title":"Adv Immunol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib33","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1146\/annurev.immunol.26.021607.090257","article-title":"Development of secondary lymphoid organs","volume":"26","author":"Randall","year":"2008","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib34","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1679\/aohc.63.81","article-title":"The presence of specialized epithelial cells on the bronchus-associated lymphoid tissue (BALT) in the mouse","volume":"63","author":"Tango","year":"2000","journal-title":"Arch Histol Cytol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib35","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.smim.2007.12.004","article-title":"Ectopic lymphoid tissues and local immunity","volume":"20","author":"Carragher","year":"2008","journal-title":"Semin Immunol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib36","doi-asserted-by":"crossref","first-page":"3183","DOI":"10.1172\/JCI28756","article-title":"Inducible bronchus-associated lymphoid tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis","volume":"116","author":"Rangel-Moreno","year":"2006","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.ajpath.2014.01.021_bib37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1679\/aohc.71.1","article-title":"Organization and developmental aspects of lymphatic vessels","volume":"71","author":"Ohtani","year":"2008","journal-title":"Arch Histol Cytol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib38","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/aja.1001650305","article-title":"Structure, blood supply, and lymphatic vessels of the sheep\u2019s visceral pleura","volume":"165","author":"Albertine","year":"1982","journal-title":"Am J Anat"},{"key":"10.1016\/j.ajpath.2014.01.021_bib39","series-title":"The Lung","first-page":"209","author":"Miller","year":"1937"},{"key":"10.1016\/j.ajpath.2014.01.021_bib40","doi-asserted-by":"crossref","first-page":"6319","DOI":"10.4049\/jimmunol.175.10.6319","article-title":"Immune complex-dependent remodeling of the airway vasculature in response to a chronic bacterial infection","volume":"175","author":"Aurora","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib41","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1084\/jem.20062596","article-title":"Functionally specialized junctions between endothelial cells of lymphatic vessels","volume":"204","author":"Baluk","year":"2007","journal-title":"J Exp Med"},{"key":"10.1016\/j.ajpath.2014.01.021_bib42","first-page":"2954","article-title":"TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice","volume":"119","author":"Baluk","year":"2009","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.ajpath.2014.01.021_bib43","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1093\/intimm\/dxq435","article-title":"Inflammation-induced secretion of CCL21 in lymphatic endothelium is a key regulator of integrin-mediated dendritic cell transmigration","volume":"22","author":"Johnson","year":"2010","journal-title":"Int Immunol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib44","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1084\/jem.20102392","article-title":"DC mobilization from the skin requires docking to immobilized CCL21 on lymphatic endothelium and intralymphatic crawling","volume":"208","author":"Tal","year":"2011","journal-title":"J Exp Med"},{"key":"10.1016\/j.ajpath.2014.01.021_bib45","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1182\/blood-2010-12-326447","article-title":"Tissue inflammation modulates gene expression of lymphatic endothelial cells and dendritic cell migration in a stimulus-dependent manner","volume":"118","author":"Vigl","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.ajpath.2014.01.021_bib46","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1126\/science.1228456","article-title":"Interstitial dendritic cell guidance by haptotactic chemokine gradients","volume":"339","author":"Weber","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.ajpath.2014.01.021_bib47","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1038\/nm1091","article-title":"Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity","volume":"10","author":"Moyron-Quiroz","year":"2004","journal-title":"Nat Med"},{"key":"10.1016\/j.ajpath.2014.01.021_bib48","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/mi.2010.52","article-title":"Regulation of inducible BALT formation and contribution to immunity and pathology","volume":"3","author":"Foo","year":"2010","journal-title":"Mucosal Immunol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib49","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1146\/annurev.immunol.21.090501.080131","article-title":"Ligands for L-selectin: homing, inflammation, and beyond","volume":"22","author":"Rosen","year":"2004","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib50","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1128\/IAI.5.6.953-956.1972","article-title":"Respiratory diseases in cyclophosphamide-treated mice, I: increased virulence of Mycoplasma pulmonis","volume":"5","author":"Singer","year":"1972","journal-title":"Infect Immun"},{"key":"10.1016\/j.ajpath.2014.01.021_bib51","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1111\/j.1365-2249.1994.tb05502.x","article-title":"Intranasal inoculation of Mycoplasma pulmonis in mice with severe combined immunodeficiency (SCID) causes a wasting disease with grave arthritis","volume":"98","author":"Evengard","year":"1994","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib52","doi-asserted-by":"crossref","first-page":"3485","DOI":"10.1128\/IAI.66.8.3485-3491.1998","article-title":"Roles of innate and adaptive immunity in respiratory mycoplasmosis","volume":"66","author":"Cartner","year":"1998","journal-title":"Infect Immun"},{"key":"10.1016\/j.ajpath.2014.01.021_bib53","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1084\/jem.20021244","article-title":"Vascular permeability factor\/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis","volume":"196","author":"Nagy","year":"2002","journal-title":"J Exp Med"},{"key":"10.1016\/j.ajpath.2014.01.021_bib54","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1096\/fj.03-1179fje","article-title":"VEGF-A promotes tissue repair-associated lymphatic vessel formation via VEGFR-2 and the alpha1beta1 and alpha2beta1 integrins","volume":"18","author":"Hong","year":"2004","journal-title":"FASEB J"},{"key":"10.1016\/j.ajpath.2014.01.021_bib55","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1084\/jem.20062642","article-title":"Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting","volume":"204","author":"Wirzenius","year":"2007","journal-title":"J Exp Med"},{"key":"10.1016\/j.ajpath.2014.01.021_bib56","doi-asserted-by":"crossref","first-page":"3158","DOI":"10.1182\/blood-2007-01-066811","article-title":"VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes","volume":"110","author":"Halin","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.ajpath.2014.01.021_bib57","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1172\/JCI20465","article-title":"VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment","volume":"113","author":"Cursiefen","year":"2004","journal-title":"J Clin Invest"},{"key":"10.1016\/j.ajpath.2014.01.021_bib58","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.mvr.2006.05.002","article-title":"Lymphangiogenesis in the developing lung promoted by VEGF-A","volume":"72","author":"Mallory","year":"2006","journal-title":"Microvasc Res"},{"key":"10.1016\/j.ajpath.2014.01.021_bib59","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1038\/emboj.2010.30","article-title":"VEGF receptor 2\/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts","volume":"29","author":"Nilsson","year":"2010","journal-title":"EMBO J"},{"key":"10.1016\/j.ajpath.2014.01.021_bib60","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.ccr.2010.11.001","article-title":"Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization","volume":"18","author":"Tvorogov","year":"2010","journal-title":"Cancer Cell"},{"key":"10.1016\/j.ajpath.2014.01.021_bib61","doi-asserted-by":"crossref","first-page":"2553","DOI":"10.1161\/ATVBAHA.110.214999","article-title":"Functional analyses of the bone marrow kinase in the X chromosome in vascular endothelial growth factor-induced lymphangiogenesis","volume":"30","author":"Jones","year":"2010","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib62","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1038\/nm1105","article-title":"Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung","volume":"10","author":"Lee","year":"2004","journal-title":"Nat Med"},{"key":"10.1016\/j.ajpath.2014.01.021_bib63","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/nmeth.1543","article-title":"Stabilized imaging of immune surveillance in the mouse lung","volume":"8","author":"Looney","year":"2011","journal-title":"Nat Methods"},{"key":"10.1016\/j.ajpath.2014.01.021_bib64","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s10456-013-9332-2","article-title":"Non-invasive dynamic near-infrared imaging and quantification of vascular leakage in\u00a0vivo","volume":"16","author":"Proulx","year":"2013","journal-title":"Angiogenesis"},{"key":"10.1016\/j.ajpath.2014.01.021_bib65","doi-asserted-by":"crossref","first-page":"5026","DOI":"10.1073\/pnas.0606697104","article-title":"Lymphotoxin beta receptor signaling is required for inflammatory lymphangiogenesis in the thyroid","volume":"104","author":"Furtado","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ajpath.2014.01.021_bib66","doi-asserted-by":"crossref","first-page":"2622","DOI":"10.1172\/JCI28993.","article-title":"Interaction of mature CD3+CD4+ T cells with dendritic cells triggers the development of tertiary lymphoid structures in the thyroid","volume":"116","author":"Marinkovic","year":"2006","journal-title":"J Clin Invest"},{"key":"10.1016\/j.ajpath.2014.01.021_bib67","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1038\/nm1340","article-title":"Lymphatic endothelial progenitor cells contribute to de novo lymphangiogenesis in human renal transplants","volume":"12","author":"Kerjaschki","year":"2006","journal-title":"Nat Med"},{"key":"10.1016\/j.ajpath.2014.01.021_bib68","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1097\/01.ASN.0000113316.52371.2E","article-title":"Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates","volume":"15","author":"Kerjaschki","year":"2004","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.ajpath.2014.01.021_bib69","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.it.2006.08.003","article-title":"Is defective lymphatic drainage a trigger for lymphoid neogenesis?","volume":"27","author":"Thaunat","year":"2006","journal-title":"Trends Immunol"}],"container-title":["The American Journal of Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944014000959?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944014000959?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,8,16]],"date-time":"2020-08-16T02:56:54Z","timestamp":1597546614000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002944014000959"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5]]},"references-count":69,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["S0002944014000959"],"URL":"https:\/\/doi.org\/10.1016\/j.ajpath.2014.01.021","relation":{},"ISSN":["0002-9440"],"issn-type":[{"value":"0002-9440","type":"print"}],"subject":[],"published":{"date-parts":[[2014,5]]}}}