{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:53:57Z","timestamp":1761490437666,"version":"3.37.3"},"reference-count":51,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,13]],"date-time":"2019-12-13T00:00:00Z","timestamp":1576195200000},"content-version":"vor","delay-in-days":711,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100007880","name":"Johns Hopkins University","doi-asserted-by":"publisher","award":["P30AI094189","R01NS097221","K01OD018244","P01MH070306","T32OD011089","P40OD0131117","R01NS089482","K01OD021323","R01NS077869"],"award-info":[{"award-number":["P30AI094189","R01NS097221","K01OD018244","P01MH070306","T32OD011089","P40OD0131117","R01NS089482","K01OD021323","R01NS077869"]}],"id":[{"id":"10.13039\/100007880","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30AI094189","R01NS097221","K01OD018244","P01MH070306","T32OD011089","P40OD0131117","R01NS089482","K01OD021323","R01NS077869"],"award-info":[{"award-number":["P30AI094189","R01NS097221","K01OD018244","P01MH070306","T32OD011089","P40OD0131117","R01NS089482","K01OD021323","R01NS077869"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","ajp.amjpathol.org","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Pathology"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.ajpath.2017.08.035","type":"journal-article","created":{"date-parts":[[2017,12,8]],"date-time":"2017-12-08T14:30:19Z","timestamp":1512743419000},"page":"125-134","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Lymphocyte-Dominant Encephalitis and Meningitis in Simian Immunodeficiency Virus\u2013Infected Macaques Receiving Antiretroviral Therapy"],"prefix":"10.1016","volume":"188","author":[{"given":"Lisa M.","family":"Mangus","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah E.","family":"Beck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne E.","family":"Queen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel A.","family":"Brill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin N.","family":"Shirk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly A.","family":"Metcalf Pate","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4550-3755","authenticated-orcid":false,"given":"Dillon C.","family":"Muth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert J.","family":"Adams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9511-012X","authenticated-orcid":false,"given":"Lucio","family":"Gama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janice E.","family":"Clements","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph L.","family":"Mankowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajpath.2017.08.035_bib1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1093\/infdis\/jis326","article-title":"Central nervous system viral invasion and inflammation during acute HIV infection","volume":"206","author":"Valcour","year":"2012","journal-title":"J Infect Dis"},{"key":"10.1016\/j.ajpath.2017.08.035_bib2","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/imr.12068","article-title":"Monocyte\/macrophages and their role in HIV neuropathogenesis","volume":"254","author":"Burdo","year":"2013","journal-title":"Immunol Rev"},{"key":"10.1016\/j.ajpath.2017.08.035_bib3","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1086\/343768","article-title":"The central nervous system as a reservoir for simian immunodeficiency virus (SIV): steady-state levels of SIV DNA in brain from acute through asymptomatic infection","volume":"186","author":"Clements","year":"2002","journal-title":"J Infect Dis"},{"key":"10.1016\/j.ajpath.2017.08.035_bib4","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1111\/j.1750-3639.1991.tb00653.x","article-title":"HIV-associated disease of the nervous system: review of nomenclature and proposal for neuropathology-based terminology","volume":"1","author":"Budka","year":"1991","journal-title":"Brain Pathol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib5","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1750-3639.1991.tb00656.x","article-title":"Neuropathology of human immunodeficiency virus infection","volume":"1","author":"Budka","year":"1991","journal-title":"Brain Pathol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib6","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1093\/ije\/dyu092","article-title":"Cohort profile: recruitment cohorts in the neuropsychological substudy of the Multicenter AIDS Cohort Study","volume":"44","author":"Becker","year":"2015","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib7","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1212\/WNL.43.11.2245","article-title":"Dementia in AIDS patients: incidence and risk factors. Multicenter AIDS Cohort Study","volume":"43","author":"McArthur","year":"1993","journal-title":"Neurology"},{"key":"10.1016\/j.ajpath.2017.08.035_bib8","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1212\/WNL.0b013e318200d727","article-title":"HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy CHARTER Study","volume":"75","author":"Heaton","year":"2010","journal-title":"Neurology"},{"key":"10.1016\/j.ajpath.2017.08.035_bib9","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1038\/nrneurol.2016.27","article-title":"HIV-associated neurocognitive disorder\u2013pathogenesis and prospects for treatment","volume":"12","author":"Saylor","year":"2016","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib10","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1007\/s11904-015-0266-8","article-title":"Neuropathology of HAND with suppressive antiretroviral therapy: encephalitis and neurodegeneration reconsidered","volume":"12","author":"Gelman","year":"2015","journal-title":"Curr HIV\/AIDS Rep"},{"key":"10.1016\/j.ajpath.2017.08.035_bib11","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/QAI.0000000000000532","article-title":"Plasma and cerebrospinal fluid biomarkers predict cerebral injury in HIV-infected individuals on stable combination antiretroviral therapy","volume":"69","author":"Anderson","year":"2015","journal-title":"J Acquir Immune Defic Syndr"},{"key":"10.1016\/j.ajpath.2017.08.035_bib12","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1097\/QAD.0b013e32836010bd","article-title":"Elevated sCD163 in plasma but not cerebrospinal fluid is a marker of neurocognitive impairment in HIV infection","volume":"27","author":"Burdo","year":"2013","journal-title":"AIDS"},{"key":"10.1016\/j.ajpath.2017.08.035_bib13","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1097\/QAI.0b013e318256f3bc","article-title":"Monocyte activation markers in cerebrospinal fluid associated with impaired neurocognitive testing in advanced HIV infection","volume":"60","author":"Kamat","year":"2012","journal-title":"J Acquir Immune Defic Syndr"},{"key":"10.1016\/j.ajpath.2017.08.035_bib14","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1097\/QAD.0000000000000580","article-title":"Cerebrospinal fluid metabolomics implicate bioenergetic adaptation as a neural mechanism regulating shifts in cognitive states of HIV-infected patients","volume":"29","author":"Dickens","year":"2015","journal-title":"AIDS"},{"key":"10.1016\/j.ajpath.2017.08.035_bib15","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1097\/QAD.0000000000000303","article-title":"Cerebrospinal fluid metabolomics reveals altered waste clearance and accelerated aging in HIV patients with neurocognitive impairment","volume":"28","author":"Cassol","year":"2014","journal-title":"AIDS"},{"key":"10.1016\/j.ajpath.2017.08.035_bib16","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s13365-013-0162-1","article-title":"Progressive cerebral injury in the setting of chronic HIV infection and antiretroviral therapy","volume":"19","author":"Gongvatana","year":"2013","journal-title":"J Neurovirol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib17","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1212\/WNL.0b013e3182478d64","article-title":"Role of obesity, metabolic variables, and diabetes in HIV-associated neurocognitive disorder","volume":"78","author":"McCutchan","year":"2012","journal-title":"Neurology"},{"key":"10.1016\/j.ajpath.2017.08.035_bib18","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1086\/503903","article-title":"Immune reconstitution syndrome in HIV: validating a case definition and identifying clinical predictors in persons initiating antiretroviral therapy","volume":"42","author":"Robertson","year":"2006","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ajpath.2017.08.035_bib19","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1212\/01.wnl.0000227922.22293.93","article-title":"Immune reconstitution inflammatory syndrome in the CNS of HIV-infected patients","volume":"67","author":"Venkataramana","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.ajpath.2017.08.035_bib20","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1111\/j.1749-6632.2009.05111.x","article-title":"Neurological complications of immune reconstitution in HIV-infected populations","volume":"1184","author":"Johnson","year":"2010","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.ajpath.2017.08.035_bib21","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1093\/brain\/awq365","article-title":"Pathogenesis of the immune reconstitution inflammatory syndrome affecting the central nervous system in patients infected with HIV","volume":"134","author":"Martin-Blondel","year":"2011","journal-title":"Brain"},{"key":"10.1016\/j.ajpath.2017.08.035_bib22","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1097\/NEN.0b013e318181b4da","article-title":"Immune reconstitution inflammatory syndrome of the brain: case illustrations of a challenging entity","volume":"67","author":"Rushing","year":"2008","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib23","doi-asserted-by":"crossref","first-page":"13588","DOI":"10.1073\/pnas.1308673110","article-title":"Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein","volume":"110","author":"Johnson","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ajpath.2017.08.035_bib24","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1080\/13550280802304753","article-title":"Progressive tumefactive inflammatory central nervous system demyelinating disease in an acquired immunodeficiency syndrome patient treated with highly active antiretroviral therapy","volume":"14","author":"Lindzen","year":"2008","journal-title":"J Neurovirol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib25","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1097\/QAD.0b013e328355e6b2","article-title":"Cerebrospinal fluid HIV escape associated with progressive neurologic dysfunction in patients on antiretroviral therapy with well controlled plasma viral load","volume":"26","author":"Peluso","year":"2012","journal-title":"AIDS"},{"key":"10.1016\/j.ajpath.2017.08.035_bib26","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s00401-004-0852-0","article-title":"Cerebral CD8+ lymphocytosis in HIV-1 infected patients with immune restoration induced by HAART","volume":"108","author":"Miller","year":"2004","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib27","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/bpa.12038","article-title":"Encephalitis with infiltration by CD8+ lymphocytes in HIV patients receiving combination antiretroviral treatment","volume":"23","author":"Gray","year":"2013","journal-title":"Brain Pathol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib28","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1093\/cid\/cit175","article-title":"CD8 encephalitis in HIV-infected patients receiving cART: a treatable entity","volume":"57","author":"Lescure","year":"2013","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ajpath.2017.08.035_bib29","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1097\/COH.0000000000000107","article-title":"New insights into immune reconstitution inflammatory syndrome of the central nervous system","volume":"9","author":"Johnson","year":"2014","journal-title":"Curr Opin HIV AIDS"},{"key":"10.1016\/j.ajpath.2017.08.035_bib30","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1097\/COH.0000000000000243","article-title":"Immune activation in the central nervous system throughout the course of HIV infection","volume":"11","author":"Spudich","year":"2016","journal-title":"Curr Opin HIV AIDS"},{"key":"10.1016\/j.ajpath.2017.08.035_bib31","doi-asserted-by":"crossref","first-page":"10480","DOI":"10.1128\/JVI.73.12.10480-10488.1999","article-title":"High viral load in the cerebrospinal fluid and brain correlates with severity of simian immunodeficiency virus encephalitis","volume":"73","author":"Zink","year":"1999","journal-title":"J Virol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib32","doi-asserted-by":"crossref","first-page":"9167","DOI":"10.1128\/JVI.00366-11","article-title":"Replication-competent simian immunodeficiency virus (SIV) gag escape mutations archived in latent reservoirs during antiretroviral treatment of SIV-infected macaques","volume":"85","author":"Queen","year":"2011","journal-title":"J Virol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib33","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1086\/653213","article-title":"Simian immunodeficiency virus-infected macaques treated with highly active antiretroviral therapy have reduced central nervous system viral replication and inflammation but persistence of viral DNA","volume":"202","author":"Zink","year":"2010","journal-title":"J Infect Dis"},{"key":"10.1016\/j.ajpath.2017.08.035_bib34","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1097\/QAD.0b013e32834a40cd","article-title":"CD4 nadir is a predictor of HIV neurocognitive impairment in the era of combination antiretroviral therapy","volume":"25","author":"Ellis","year":"2011","journal-title":"AIDS"},{"key":"10.1016\/j.ajpath.2017.08.035_bib35","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.ejphar.2015.03.018","article-title":"Paving the path to HIV neurotherapy: predicting SIV CNS disease","volume":"759","author":"Beck","year":"2015","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib36","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1002\/jcb.25606","article-title":"Fully automated RNAscope in situ hybridization assays for formalin-fixed paraffin-embedded cells and tissues","volume":"117","author":"Anderson","year":"2016","journal-title":"J Cell Biochem"},{"key":"10.1016\/j.ajpath.2017.08.035_bib37","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1097\/QAD.0000000000001267","article-title":"Reactivation of simian immunodeficiency virus reservoirs in the brain of virally suppressed macaques","volume":"31","author":"Gama","year":"2017","journal-title":"AIDS"},{"key":"10.1016\/j.ajpath.2017.08.035_bib38","first-page":"208","article-title":"Searching for clues: tracking the pathogenesis of human immunodeficiency virus central nervous system disease by use of an accelerated, consistent simian immunodeficiency virus macaque model","volume":"186 Suppl 2","author":"Mankowski","year":"2002","journal-title":"J Infect Dis"},{"key":"10.1016\/j.ajpath.2017.08.035_bib39","first-page":"793","article-title":"Pathogenesis of SIV encephalitis. Selection and replication of neurovirulent SIV","volume":"151","author":"Zink","year":"1997","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib40","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1086\/650538","article-title":"Discordance between cerebral spinal fluid and plasma HIV replication in patients with neurological symptoms who are receiving suppressive antiretroviral therapy","volume":"50","author":"Canestri","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ajpath.2017.08.035_bib41","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1097\/QAD.0b013e32832c4101","article-title":"Severe aseptic leucoencephalopathy as immune reconstitution inflammatory syndrome in Caucasian and African patients","volume":"23","author":"Ringelstein","year":"2009","journal-title":"AIDS"},{"key":"10.1016\/j.ajpath.2017.08.035_bib42","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3389\/fneur.2013.00012","article-title":"Late onset CNS immune reconstitution inflammatory syndrome in an immunocompetent patient","volume":"4","author":"Hornik","year":"2013","journal-title":"Front Neurol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib43","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1007\/s13365-013-0161-2","article-title":"Reversible severe encephalitis and word deafness following rapid immune reconstitution in AIDS: a case report","volume":"19","author":"Roh","year":"2013","journal-title":"J Neurovirol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib44","doi-asserted-by":"crossref","first-page":"5571","DOI":"10.1182\/blood-2010-05-285528","article-title":"B cells in early and chronic HIV infection: evidence for preservation of immune function associated with early initiation of antiretroviral therapy","volume":"116","author":"Moir","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.ajpath.2017.08.035_bib45","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1056\/NEJMoa1110187","article-title":"Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy","volume":"368","author":"Le","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajpath.2017.08.035_bib46","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1111\/j.1468-1293.2005.00281.x","article-title":"Effects of antiretroviral treatment on blood-brain barrier integrity and intrathecal immunoglobulin production in neuroasymptomatic HIV-1-infected patients","volume":"6","author":"Abdulle","year":"2005","journal-title":"HIV Med"},{"key":"10.1016\/j.ajpath.2017.08.035_bib47","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.jneuroim.2015.05.015","article-title":"Compartmentalized intrathecal immunoglobulin synthesis during HIV infection - a model of chronic CNS inflammation?","volume":"285","author":"Bonnan","year":"2015","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib48","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/BF00314332","article-title":"Analysis of oligoclonal antibody bands against individual HIV structural proteins in the CSF of patients infected with HIV","volume":"236","author":"Kaiser","year":"1989","journal-title":"J Neurol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib49","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1002\/ana.410260504","article-title":"Low prevalence of neurological and neuropsychological abnormalities in otherwise healthy HIV-1-infected individuals: results from the multicenter AIDS Cohort Study","volume":"26","author":"McArthur","year":"1989","journal-title":"Ann Neurol"},{"key":"10.1016\/j.ajpath.2017.08.035_bib50","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1093\/brain\/awg118","article-title":"B lymphocytes in the normal brain: contrasts with HIV-associated lymphoid infiltrates and lymphomas","volume":"126","author":"Anthony","year":"2003","journal-title":"Brain"},{"key":"10.1016\/j.ajpath.2017.08.035_bib51","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/1742-2094-7-79","article-title":"Antibodies to myelin oligodendrocyte glycoprotein in HIV-1 associated neurocognitive disorder: a cross-sectional cohort study","volume":"7","author":"Lackner","year":"2010","journal-title":"J Neuroinflammation"}],"container-title":["The American Journal of Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944017306764?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944017306764?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,3,31]],"date-time":"2021-03-31T23:56:19Z","timestamp":1617234979000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002944017306764"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":51,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["S0002944017306764"],"URL":"https:\/\/doi.org\/10.1016\/j.ajpath.2017.08.035","relation":{},"ISSN":["0002-9440"],"issn-type":[{"type":"print","value":"0002-9440"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lymphocyte-Dominant Encephalitis and Meningitis in Simian Immunodeficiency Virus\u2013Infected Macaques Receiving Antiretroviral Therapy","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajpath.2017.08.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 American Society for Investigative Pathology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}