{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T22:51:23Z","timestamp":1782255083620,"version":"3.54.5"},"reference-count":52,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["F31AA028423"],"award-info":[{"award-number":["F31AA028423"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["F32AA027950"],"award-info":[{"award-number":["F32AA027950"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P50AA011999"],"award-info":[{"award-number":["P50AA011999"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AA023681"],"award-info":[{"award-number":["R01AA023681"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AA024102"],"award-info":[{"award-number":["R01AA024102"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21AA028117"],"award-info":[{"award-number":["R21AA028117"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32ES011564"],"award-info":[{"award-number":["T32ES011564"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01AA021886"],"award-info":[{"award-number":["U01AA021886"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01AA021918"],"award-info":[{"award-number":["U01AA021918"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01AA026926"],"award-info":[{"award-number":["U01AA026926"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01AA026934"],"award-info":[{"award-number":["U01AA026934"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01AA026980"],"award-info":[{"award-number":["U01AA026980"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000015","name":"U.S. Department of Energy","doi-asserted-by":"publisher","award":["DE-AC05-76RLO 1830"],"award-info":[{"award-number":["DE-AC05-76RLO 1830"]}],"id":[{"id":"10.13039\/100000015","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["P50AA024337"],"award-info":[{"award-number":["P50AA024337"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["P20GM113226"],"award-info":[{"award-number":["P20GM113226"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["P41GM103493"],"award-info":[{"award-number":["P41GM103493"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"publisher","award":["I01BX000350"],"award-info":[{"award-number":["I01BX000350"]}],"id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajp.amjpathol.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Pathology"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.ajpath.2022.04.004","type":"journal-article","created":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T12:14:30Z","timestamp":1651148070000},"page":"1066-1082","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Hepatic Protein and Phosphoprotein Signatures of Alcohol-Associated Cirrhosis and Hepatitis"],"prefix":"10.1016","volume":"192","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1955-3046","authenticated-orcid":false,"given":"Josiah","family":"Hardesty","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le","family":"Day","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2022-7854","authenticated-orcid":false,"given":"Jeffrey","family":"Warner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"Warner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9992-9829","authenticated-orcid":false,"given":"Marina","family":"Gritsenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliya","family":"Asghar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Stolz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig","family":"McClain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0557-7338","authenticated-orcid":false,"given":"Jon","family":"Jacobs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina","family":"Kirpich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajpath.2022.04.004_bib1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.jhep.2018.09.014","article-title":"Burden of liver diseases in the world","volume":"70","author":"Asrani","year":"2019","journal-title":"J Hepatol"},{"key":"10.1016\/j.ajpath.2022.04.004_bib2","series-title":"Liver Cirrhosis Mortality in the United States: National, State, and Regional Trends, 2000-2017","first-page":"1","author":"Young-Hee Yoon","year":"2019"},{"key":"10.1016\/j.ajpath.2022.04.004_bib3","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/hep.23258","article-title":"Alcoholic liver disease","volume":"51","author":"O'Shea","year":"2010","journal-title":"Hepatology"},{"key":"10.1016\/j.ajpath.2022.04.004_bib4","doi-asserted-by":"crossref","first-page":"2758","DOI":"10.1056\/NEJMra0805786","article-title":"Alcoholic hepatitis","volume":"360","author":"Lucey","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajpath.2022.04.004_bib5","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1002\/hep.27779","article-title":"Systemic inflammatory response and serum lipopolysaccharide levels predict multiple organ failure and death in alcoholic hepatitis","volume":"62","author":"Michelena","year":"2015","journal-title":"Hepatology"},{"key":"10.1016\/j.ajpath.2022.04.004_bib6","series-title":"Alcohol Sales During the COVID-19 Pandemic","year":"2021"},{"key":"10.1016\/j.ajpath.2022.04.004_bib7","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1002\/hep4.1706","article-title":"COVID-19 aftershocks on alcohol-associated liver disease: an early cross-sectional report from the U.S. epicenter","volume":"5","author":"Rutledge","year":"2021","journal-title":"Hepatol Commun"},{"key":"10.1016\/j.ajpath.2022.04.004_bib8","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1002\/hep4.1747","article-title":"Alcohol-associated liver disease before and after COVID-19-an overview and call for ongoing investigation","volume":"5","author":"Moon","year":"2021","journal-title":"Hepatol Commun"},{"key":"10.1016\/j.ajpath.2022.04.004_bib9","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.jhep.2018.10.026","article-title":"Current trials and novel therapeutic targets for alcoholic hepatitis","volume":"70","author":"Singal","year":"2019","journal-title":"J Hepatol"},{"key":"10.1016\/j.ajpath.2022.04.004_bib10","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1053\/j.gastro.2020.06.014","article-title":"Genome-wide association study for alcohol-related cirrhosis identifies risk loci in MARC1 and HNRNPUL1","volume":"159","author":"Innes","year":"2020","journal-title":"Gastroenterology"},{"key":"10.1016\/j.ajpath.2022.04.004_bib11","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1080\/00365521.2017.1359664","article-title":"An exploratory genome-wide analysis of genetic risk for alcoholic hepatitis","volume":"52","author":"Beaudoin","year":"2017","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.ajpath.2022.04.004_bib12","doi-asserted-by":"crossref","first-page":"3126","DOI":"10.1038\/s41467-019-11004-3","article-title":"Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis","volume":"10","author":"Argemi","year":"2019","journal-title":"Nat Commun"},{"key":"10.1016\/j.ajpath.2022.04.004_bib13","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1053\/j.gastro.2020.12.008","article-title":"Integrated multiomics reveals glucose use reprogramming and identifies a novel hexokinase in alcoholic hepatitis","volume":"160","author":"Massey","year":"2021","journal-title":"Gastroenterology"},{"key":"10.1016\/j.ajpath.2022.04.004_bib14","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1002\/hep4.1686","article-title":"Linoleic acid-derived oxylipins differentiate early stage alcoholic hepatitis from mild alcohol-associated liver injury","volume":"5","author":"Warner","year":"2021","journal-title":"Hepatol Commun"},{"key":"10.1016\/j.ajpath.2022.04.004_bib15","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1038\/s41586-019-1742-x","article-title":"Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease","volume":"575","author":"Duan","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.ajpath.2022.04.004_bib16","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1002\/hep.21318","article-title":"HepatoProteomics: applying proteomic technologies to the study of liver function and disease","volume":"44","author":"Diamond","year":"2006","journal-title":"Hepatology"},{"key":"10.1016\/j.ajpath.2022.04.004_bib17","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1002\/pmic.201000722","article-title":"Reversed-phase chromatography with multiple fraction concatenation strategy for proteome profiling of human MCF10A cells","volume":"11","author":"Wang","year":"2011","journal-title":"Proteomics"},{"key":"10.1016\/j.ajpath.2022.04.004_bib18","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1038\/s41596-018-0006-9","article-title":"Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography-mass spectrometry","volume":"13","author":"Mertins","year":"2018","journal-title":"Nat Protoc"},{"key":"10.1016\/j.ajpath.2022.04.004_bib19","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.cell.2016.05.069","article-title":"Integrated proteogenomic characterization of human high-grade serous ovarian cancer","volume":"166","author":"Zhang","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.ajpath.2022.04.004_bib20","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nmeth1019","article-title":"Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry","volume":"4","author":"Elias","year":"2007","journal-title":"Nat Methods"},{"key":"10.1016\/j.ajpath.2022.04.004_bib21","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1021\/pr0498638","article-title":"Probability-based evaluation of peptide and protein identifications from tandem mass spectrometry and SEQUEST analysis: the human proteome","volume":"4","author":"Qian","year":"2005","journal-title":"J Proteome Res"},{"key":"10.1016\/j.ajpath.2022.04.004_bib22","doi-asserted-by":"crossref","first-page":"3354","DOI":"10.1021\/pr8001244","article-title":"Spectral probabilities and generating functions of tandem mass spectra: a strike against decoy databases","volume":"7","author":"Kim","year":"2008","journal-title":"J Proteome Res"},{"key":"10.1016\/j.ajpath.2022.04.004_bib23","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.3390\/ijms22041582","article-title":"Ileum gene expression in response to acute systemic inflammation in mice chronically fed ethanol: beneficial effects of elevated tissue n-3 PUFAs","volume":"22","author":"Hardesty","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.ajpath.2022.04.004_bib24","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1186\/1471-2105-7-191","article-title":"STEM: a tool for the analysis of short time series gene expression data","volume":"7","author":"Ernst","year":"2006","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.ajpath.2022.04.004_bib25","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1053\/jhep.2001.22172","article-title":"A model to predict survival in patients with end-stage liver disease","volume":"33","author":"Kamath","year":"2001","journal-title":"Hepatology"},{"key":"10.1016\/j.ajpath.2022.04.004_bib26","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1016\/j.jhep.2021.05.041","article-title":"Loss of hepatocyte identity following aberrant YAP activation: a key mechanism in alcoholic hepatitis","volume":"75","author":"Bou Saleh","year":"2021","journal-title":"J Hepatol"},{"key":"10.1016\/j.ajpath.2022.04.004_bib27","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1101\/gad.1843810","article-title":"A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)","volume":"24","author":"Zhao","year":"2010","journal-title":"Genes Dev"},{"key":"10.1016\/j.ajpath.2022.04.004_bib28","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1053\/j.gastro.2019.07.029","article-title":"Fibrogenic activity of MECP2 is regulated by phosphorylation in hepatic stellate cells","volume":"157","author":"Moran-Salvador","year":"2019","journal-title":"Gastroenterology"},{"key":"10.1016\/j.ajpath.2022.04.004_bib29","doi-asserted-by":"crossref","first-page":"2894","DOI":"10.1128\/MCB.06728-11","article-title":"Phosphorylation of distinct sites in MeCP2 modifies cofactor associations and the dynamics of transcriptional regulation","volume":"32","author":"Gonzales","year":"2012","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.ajpath.2022.04.004_bib30","doi-asserted-by":"crossref","first-page":"2848","DOI":"10.1002\/hep.31836","article-title":"Albumin in advanced liver diseases: the good and bad of a drug!","volume":"74","author":"Jagdish","year":"2021","journal-title":"Hepatology"},{"key":"10.1016\/j.ajpath.2022.04.004_bib31","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1016\/j.cell.2015.05.028","article-title":"A single kinase generates the majority of the secreted phosphoproteome","volume":"161","author":"Tagliabracci","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.ajpath.2022.04.004_bib32","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.4049\/jimmunol.1301410","article-title":"Complement component C5 recruits neutrophils in the absence of C3 during respiratory infection with modified vaccinia virus Ankara","volume":"194","author":"Price","year":"2015","journal-title":"J Immunol"},{"key":"10.1016\/j.ajpath.2022.04.004_bib33","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1038\/s41392-020-0128-8","article-title":"Mitochondrial dysfunction and alcohol-associated liver disease: a novel pathway and therapeutic target","volume":"5","author":"Abdallah","year":"2020","journal-title":"Signal Transduct Target Ther"},{"key":"10.1016\/j.ajpath.2022.04.004_bib34","doi-asserted-by":"crossref","first-page":"90","DOI":"10.3389\/fcell.2017.00090","article-title":"Role of cardiolipin in mitochondrial signaling pathways","volume":"5","author":"Dudek","year":"2017","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.ajpath.2022.04.004_bib35","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1042\/BJ20040655","article-title":"On the mechanism of the increase in cardiolipin biosynthesis and resynthesis in hepatocytes during rat liver regeneration","volume":"386","author":"Webster","year":"2005","journal-title":"Biochem J"},{"key":"10.1016\/j.ajpath.2022.04.004_bib36","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.tem.2021.01.006","article-title":"Cardiolipin, mitochondria, and neurological disease","volume":"32","author":"Falabella","year":"2021","journal-title":"Trends Endocrinol Metab"},{"key":"10.1016\/j.ajpath.2022.04.004_bib37","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1172\/JCI132691","article-title":"Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis","volume":"130","author":"Hyun","year":"2020","journal-title":"J Clin Invest"},{"key":"10.1016\/j.ajpath.2022.04.004_bib38","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1258\/ebm.2011.010360","article-title":"The emerging role of autophagy in alcoholic liver disease","volume":"236","author":"Ding","year":"2011","journal-title":"Exp Biol Med (Maywood)"},{"key":"10.1016\/j.ajpath.2022.04.004_bib39","doi-asserted-by":"crossref","first-page":"4962","DOI":"10.1038\/s41467-018-07338-z","article-title":"Autophagy is a gatekeeper of hepatic differentiation and carcinogenesis by controlling the degradation of Yap","volume":"9","author":"Lee","year":"2018","journal-title":"Nat Commun"},{"key":"10.1016\/j.ajpath.2022.04.004_bib40","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.jhep.2015.04.011","article-title":"The Hippo pathway effector YAP controls mouse hepatic stellate cell activation","volume":"63","author":"Mannaerts","year":"2015","journal-title":"J Hepatol"},{"key":"10.1016\/j.ajpath.2022.04.004_bib41","doi-asserted-by":"crossref","first-page":"G471","DOI":"10.1152\/ajpgi.00153.2017","article-title":"Proliferation of hepatic stellate cells, mediated by YAP and TAZ, contributes to liver repair and regeneration after liver ischemia-reperfusion injury","volume":"314","author":"Konishi","year":"2018","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.ajpath.2022.04.004_bib42","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1002\/hep4.1232","article-title":"Hepatic nuclear receptor expression associates with features of histology in pediatric nonalcoholic fatty liver disease","volume":"2","author":"Elbel","year":"2018","journal-title":"Hepatol Commun"},{"key":"10.1016\/j.ajpath.2022.04.004_bib43","doi-asserted-by":"crossref","first-page":"e0219764","DOI":"10.1371\/journal.pone.0219764","article-title":"AEBP1 expression increases with severity of fibrosis in NASH and is regulated by glucose, palmitate, and miR-372-3p","volume":"14","author":"Gerhard","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.ajpath.2022.04.004_bib44","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/j.jhep.2016.11.003","article-title":"The orphan nuclear receptor COUP-TFII coordinates hypoxia-independent proangiogenic responses in hepatic stellate cells","volume":"66","author":"Ceni","year":"2017","journal-title":"J Hepatol"},{"key":"10.1016\/j.ajpath.2022.04.004_bib45","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/S0092-8674(00)81887-5","article-title":"MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin","volume":"88","author":"Nan","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.ajpath.2022.04.004_bib46","doi-asserted-by":"crossref","first-page":"C748","DOI":"10.1152\/ajpcell.00019.2005","article-title":"Constitutive secretion of serum albumin requires reversible protein tyrosine phosphorylation events in trans-Golgi","volume":"289","author":"Webb","year":"2005","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.ajpath.2022.04.004_bib47","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1056\/NEJMoa2022166","article-title":"A randomized trial of albumin infusions in hospitalized patients with cirrhosis","volume":"384","author":"China","year":"2021","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajpath.2022.04.004_bib48","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1002\/hep.31419","article-title":"Diagnostic and prognostic significance of complement in patients with alcohol-associated hepatitis","volume":"73","author":"Fan","year":"2021","journal-title":"Hepatology"},{"key":"10.1016\/j.ajpath.2022.04.004_bib49","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/s41423-020-0412-0","article-title":"Neutrophil chemoattractant receptors in health and disease: double-edged swords","volume":"17","author":"Metzemaekers","year":"2020","journal-title":"Cell Mol Immunol"},{"key":"10.1016\/j.ajpath.2022.04.004_bib50","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1002\/hep.21737","article-title":"Neutrophil dysfunction in alcoholic hepatitis superimposed on cirrhosis is reversible and predicts the outcome","volume":"46","author":"Mookerjee","year":"2007","journal-title":"Hepatology"},{"key":"10.1016\/j.ajpath.2022.04.004_bib51","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1053\/j.gastro.2014.01.018","article-title":"A histologic scoring system for prognosis of patients with alcoholic hepatitis","volume":"146","author":"Altamirano","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.ajpath.2022.04.004_bib52","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1136\/gut.49.6.852","article-title":"Antiphospholipid antibodies associated with alcoholic liver disease specifically recognise oxidised phospholipids","volume":"49","author":"Rolla","year":"2001","journal-title":"Gut"}],"container-title":["The American Journal of Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944022001213?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944022001213?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T16:41:32Z","timestamp":1757695292000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002944022001213"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":52,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["S0002944022001213"],"URL":"https:\/\/doi.org\/10.1016\/j.ajpath.2022.04.004","relation":{},"ISSN":["0002-9440"],"issn-type":[{"value":"0002-9440","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hepatic Protein and Phosphoprotein Signatures of Alcohol-Associated Cirrhosis and Hepatitis","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajpath.2022.04.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 American Society for Investigative Pathology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}