{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T15:13:34Z","timestamp":1791472414950,"version":"4.3.4"},"reference-count":58,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R01 HD088712"],"award-info":[{"award-number":["R01 HD088712"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajp.amjpathol.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Pathology"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.ajpath.2023.04.007","type":"journal-article","created":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T20:41:06Z","timestamp":1683578466000},"page":"1046-1058","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Neurotrophins and Their Receptors, Novel Therapeutic Targets for Pelvic Pain in Endometriosis, Are Coordinately Regulated by IL-1\u03b2 via the JNK Signaling Pathway"],"prefix":"10.1016","volume":"193","author":[{"given":"Jie","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1885-0401","authenticated-orcid":false,"given":"Sarah L.","family":"Berga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew D.","family":"Schrepf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J.","family":"Clauw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sawsan","family":"As-Sanie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1423-6351","authenticated-orcid":false,"given":"Robert N.","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajpath.2023.04.007_bib1","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.ajog.2019.02.033","article-title":"Assessing research gaps and unmet needs in endometriosis","volume":"221","author":"As-Sanie","year":"2019","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajpath.2023.04.007_bib2","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1055\/s-0035-1554920","article-title":"Pathogenesis of endometriosis: roles of retinoids and inflammatory pathways","volume":"33","author":"Taylor","year":"2015","journal-title":"Semin Reprod Med"},{"key":"10.1016\/j.ajpath.2023.04.007_bib3","doi-asserted-by":"crossref","first-page":"568.e1","DOI":"10.1016\/j.ajog.2021.08.038","article-title":"Incidence and predictors of persistent pelvic pain following hysterectomy in women with chronic pelvic pain","volume":"225","author":"As-Sanie","year":"2021","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ajpath.2023.04.007_bib4","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-99177-0","article-title":"Eliapixant is a selective P2X3 receptor antagonist for the treatment of disorders associated with hypersensitive nerve fibers","volume":"11","author":"Davenport","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.ajpath.2023.04.007_bib5","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1146\/annurev-physiol-012110-142158","article-title":"Endometriosis: the role of neuroangiogenesis","volume":"73","author":"Asante","year":"2011","journal-title":"Annu Rev Physiol"},{"key":"10.1016\/j.ajpath.2023.04.007_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jpain.2015.09.008","article-title":"Functional connectivity is associated with altered brain chemistry in women with endometriosis-associated chronic pelvic pain","volume":"17","author":"As-Sanie","year":"2016","journal-title":"J Pain"},{"key":"10.1016\/j.ajpath.2023.04.007_bib7","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1177\/1933719118773405","article-title":"Spinal glial adaptations occur in a minimally invasive mouse model of endometriosis: potential implications for lesion etiology and persistent pelvic pain","volume":"26","author":"Dodds","year":"2019","journal-title":"Reprod Sci"},{"key":"10.1016\/j.ajpath.2023.04.007_bib8","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.gyobfe.2010.05.005","article-title":"Neurotrophins and pain in endometriosis","volume":"38","author":"Borghese","year":"2010","journal-title":"Gynecol Obstet Fertil"},{"key":"10.1016\/j.ajpath.2023.04.007_bib9","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1016\/S0002-9440(10)64664-0","article-title":"Regulated on activation, normal T-cell-expressed and -secreted mRNA expression in normal endometrium and endometriotic implants: assessment of autocrine\/paracrine regulation by in situ hybridization","volume":"158","author":"Hornung","year":"2001","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ajpath.2023.04.007_bib10","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.fertnstert.2007.12.067","article-title":"Expression of interleukin-8 and monocyte chemotactic protein 1 in women with endometriosis","volume":"91","author":"Ulukus","year":"2009","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ajpath.2023.04.007_bib11","doi-asserted-by":"crossref","first-page":"4270","DOI":"10.1210\/en.2017-00495","article-title":"IL-1beta inhibits connexin 43 and disrupts decidualization of human endometrial stromal cells through ERK1\/2 and p38 MAP kinase","volume":"158","author":"Yu","year":"2017","journal-title":"Endocrinology"},{"key":"10.1016\/j.ajpath.2023.04.007_bib12","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1002\/eji.201141550","article-title":"A clinical perspective of IL-1beta as the gatekeeper of inflammation","volume":"41","author":"Dinarello","year":"2011","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.ajpath.2023.04.007_bib13","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/112_2017_6","article-title":"Neurotrophin Trk receptors: new targets for cancer therapy","volume":"174","author":"Meldolesi","year":"2018","journal-title":"Rev Physiol Biochem Pharmacol"},{"key":"10.1016\/j.ajpath.2023.04.007_bib14","doi-asserted-by":"crossref","first-page":"2281","DOI":"10.1016\/j.ajpath.2018.06.011","article-title":"IL-1beta stimulates brain-derived neurotrophic factor production in eutopic endometriosis stromal cell cultures: a model for cytokine regulation of neuroangiogenesis","volume":"188","author":"Yu","year":"2018","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ajpath.2023.04.007_bib15","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.bpobgyn.2018.01.006","article-title":"Pathogenesis of endometriosis: interaction between endocrine and inflammatory pathways","volume":"50","author":"Patel","year":"2018","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"10.1016\/j.ajpath.2023.04.007_bib16","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.jsbmb.2014.12.008","article-title":"Dienogest, a synthetic progestin, down-regulates expression of CYP19A1 and inflammatory and neuroangiogenesis factors through progesterone receptor isoforms A and B in endometriotic cells","volume":"147","author":"Ichioka","year":"2015","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.ajpath.2023.04.007_bib17","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/S0015-0282(97)81391-X","article-title":"Revised American Society for Reproductive Medicine classification of endometriosis: 1996","volume":"67","year":"1997","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ajpath.2023.04.007_bib18","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.3892\/etm.2017.4794","article-title":"Circulating and peritoneal fluid interleukin-6 levels and gene expression in pelvic endometriosis","volume":"14","author":"De Andrade","year":"2017","journal-title":"Exp Ther Med"},{"key":"10.1016\/j.ajpath.2023.04.007_bib19","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1093\/molehr\/gat087","article-title":"Reduced connexin 43 in eutopic endometrium and cultured endometrial stromal cells from subjects with endometriosis","volume":"20","author":"Yu","year":"2014","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.ajpath.2023.04.007_bib20","doi-asserted-by":"crossref","first-page":"6298","DOI":"10.1002\/jcp.27360","article-title":"Curcumin attenuates proangiogenic and proinflammatory factors in human eutopic endometrial stromal cells through the NF-kappaB signaling pathway","volume":"234","author":"Chowdhury","year":"2019","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.ajpath.2023.04.007_bib21","first-page":"1118","article-title":"Interleukin-6 secretion in\u00a0vitro is up-regulated in ectopic and eutopic endometrial stromal cells from women with endometriosis","volume":"81","author":"Tseng","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ajpath.2023.04.007_bib22","doi-asserted-by":"crossref","first-page":"2432","DOI":"10.1210\/en.2015-1942","article-title":"Endometrial stromal decidualization responds reversibly to hormone stimulation and withdrawal","volume":"157","author":"Yu","year":"2016","journal-title":"Endocrinology"},{"key":"10.1016\/j.ajpath.2023.04.007_bib23","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1093\/molehr\/gaz045","article-title":"Interleukin-1beta inhibits estrogen receptor-alpha, progesterone receptors A and B and biomarkers of human endometrial stromal cell differentiation: implications for endometriosis","volume":"25","author":"Yu","year":"2019","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.ajpath.2023.04.007_bib24","first-page":"3591","article-title":"Cabergoline stimulates human endometrial stromal cell decidualization and reverses effects of interleukin-1\u03b2 in\u00a0vitro","volume":"106","author":"Yu","year":"2021","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ajpath.2023.04.007_bib25","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.mce.2011.04.011","article-title":"Disruption of gap junctions reduces biomarkers of decidualization and angiogenesis and increases inflammatory mediators in human endometrial stromal cell cultures","volume":"344","author":"Yu","year":"2011","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.ajpath.2023.04.007_bib26","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1093\/humrep\/dei368","article-title":"High density of small nerve fibres in the functional layer of the endometrium in women with endometriosis","volume":"21","author":"Tokushige","year":"2006","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ajpath.2023.04.007_bib27","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1080\/00016340903176826","article-title":"Endometriosis-associated nerve fibers and pain","volume":"88","author":"Medina","year":"2009","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.ajpath.2023.04.007_bib28","first-page":"2153","article-title":"Increased expression of neurogenic factors in uterine fibroids","volume":"34","author":"Luddi","year":"2019","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ajpath.2023.04.007_bib29","doi-asserted-by":"crossref","first-page":"4868","DOI":"10.1523\/JNEUROSCI.0249-05.2005","article-title":"TrkA is expressed in nociceptive neurons and influences electrophysiological properties via Nav1.8 expression in rapidly conducting nociceptors","volume":"25","author":"Fang","year":"2005","journal-title":"J Neurosci"},{"key":"10.1016\/j.ajpath.2023.04.007_bib30","doi-asserted-by":"crossref","first-page":"5508","DOI":"10.1523\/JNEUROSCI.4288-08.2009","article-title":"TrkB signaling is required for both the induction and maintenance of tissue and nerve injury-induced persistent pain","volume":"29","author":"Wang","year":"2009","journal-title":"J Neurosci"},{"key":"10.1016\/j.ajpath.2023.04.007_bib31","doi-asserted-by":"crossref","first-page":"3394","DOI":"10.1523\/JNEUROSCI.1686-17.2018","article-title":"Swedish nerve growth factor mutation (NGF(R100W) defines a role for TrkA and p75(NTR) in nociception","volume":"38","author":"Sung","year":"2018","journal-title":"J Neurosci"},{"key":"10.1016\/j.ajpath.2023.04.007_bib32","doi-asserted-by":"crossref","first-page":"31707","DOI":"10.1074\/jbc.M111.233486","article-title":"Human tryptase cleaves pro-nerve growth factor (pro-NGF): hints of local, mast cell-dependent regulation of NGF\/pro-NGF action","volume":"286","author":"Spinnler","year":"2011","journal-title":"J Biol Chem"},{"key":"10.1016\/j.ajpath.2023.04.007_bib33","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/nrn2297","article-title":"From inflammation to sickness and depression: when the immune system subjugates the brain","volume":"9","author":"Dantzer","year":"2008","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.ajpath.2023.04.007_bib34","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/s12020-007-0025-8","article-title":"Tyrosine receptor kinase B (TrkB) protein expression in the human endometrium","volume":"31","author":"Anger","year":"2007","journal-title":"Endocrine"},{"key":"10.1016\/j.ajpath.2023.04.007_bib35","doi-asserted-by":"crossref","first-page":"3025","DOI":"10.1093\/humrep\/dep283","article-title":"Density of small diameter sensory nerve fibres in endometrium: a semi-invasive diagnostic test for minimal to mild endometriosis","volume":"24","author":"Bokor","year":"2009","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ajpath.2023.04.007_bib36","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1007\/PL00000921","article-title":"The neurotrophic factors in non-neuronal tissues","volume":"58","author":"Sariola","year":"2001","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.ajpath.2023.04.007_bib37","first-page":"1807","article-title":"Cellular localization of the Trk neurotrophin receptor family in human non-neuronal tissues","volume":"148","author":"Shibayama","year":"1996","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ajpath.2023.04.007_bib38","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1111\/j.1365-2559.2009.03308.x","article-title":"Immunohistochemical localization of tyrosine receptor kinases A and B in endometriosis-associated ovarian cancer","volume":"54","author":"Foster","year":"2009","journal-title":"Histopathology"},{"key":"10.1016\/j.ajpath.2023.04.007_bib39","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1093\/humrep\/17.7.1895","article-title":"Hyperalgesia, nerve infiltration and nerve growth factor expression in deep adenomyotic nodules, peritoneal and ovarian endometriosis","volume":"17","author":"Anaf","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ajpath.2023.04.007_bib40","doi-asserted-by":"crossref","first-page":"3001","DOI":"10.1093\/humrep\/del260","article-title":"Nerve fibres in peritoneal endometriosis","volume":"21","author":"Tokushige","year":"2006","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ajpath.2023.04.007_bib41","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1093\/humrep\/den464","article-title":"Rich innervation of deep infiltrating endometriosis","volume":"24","author":"Wang","year":"2009","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ajpath.2023.04.007_bib42","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1038\/s41467-018-04648-0","article-title":"A multi-modal MRI study of the central response to inflammation in rheumatoid arthritis","volume":"9","author":"Schrepf","year":"2018","journal-title":"Nat Commun"},{"key":"10.1016\/j.ajpath.2023.04.007_bib43","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/S0015-0282(16)57506-2","article-title":"Interleukin-8 concentrations are elevated in peritoneal fluid of women with endometriosis","volume":"63","author":"Ryan","year":"1995","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ajpath.2023.04.007_bib44","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1093\/aje\/kwx272","article-title":"A prospective study of inflammatory markers and risk of endometriosis","volume":"187","author":"Mu","year":"2018","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.ajpath.2023.04.007_bib45","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.lfs.2003.11.034","article-title":"A study of serum malondialdehyde and interleukin-6 levels in young women with dysmenorrhea in Taiwan","volume":"75","author":"Yeh","year":"2004","journal-title":"Life Sci"},{"key":"10.1016\/j.ajpath.2023.04.007_bib46","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1093\/humrep\/del419","article-title":"Serum interleukin-6 levels are elevated in women with minimal-mild endometriosis","volume":"22","author":"Mart\u00ednez","year":"2007","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ajpath.2023.04.007_bib47","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1093\/humrep\/deaa017","article-title":"Role of interleukin-1\u03b2 in nerve growth factor expression, neurogenesis and\u00a0deep dyspareunia in endometriosis","volume":"35","author":"Peng","year":"2020","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ajpath.2023.04.007_bib48","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.fertnstert.2012.05.027","article-title":"Proteomic identification of neurotrophins in the eutopic endometrium of women with endometriosis","volume":"98","author":"Browne","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ajpath.2023.04.007_bib49","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1507\/endocrj.EJ13-0027","article-title":"Possible involvement of nerve growth factor in dysmenorrhea and dyspareunia associated with endometriosis","volume":"60","author":"Kajitani","year":"2013","journal-title":"Endocr J"},{"key":"10.1016\/j.ajpath.2023.04.007_bib50","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.cyto.2013.03.003","article-title":"Evidence of neurotrophic events due to peritoneal endometriotic lesions","volume":"62","author":"Barcena de Arellano","year":"2013","journal-title":"Cytokine"},{"key":"10.1016\/j.ajpath.2023.04.007_bib51","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1177\/1933719115600553","article-title":"Bentamapimod (JNK inhibitor AS602801) induces regression of endometriotic lesions in animal models","volume":"23","author":"Palmer","year":"2016","journal-title":"Reprod Sci"},{"key":"10.1016\/j.ajpath.2023.04.007_bib52","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/j.fertnstert.2015.11.022","article-title":"c-Jun NH2-terminal kinase inhibitor bentamapimod reduces induced endometriosis in baboons: an assessor-blind placebo-controlled randomized study","volume":"105","author":"Hussein","year":"2016","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ajpath.2023.04.007_bib53","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1177\/1352458510381258","article-title":"Characterization of immune cell subsets during the active phase of multiple sclerosis reveals disease and c-Jun N-terminal kinase pathway biomarkers","volume":"17","author":"Ferrandi","year":"2011","journal-title":"Mult Scler"},{"key":"10.1016\/j.ajpath.2023.04.007_bib54","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s10875-009-9274-z","article-title":"NF-kappaB decoy oligonucleotides suppress RANTES expression and monocyte chemotactic activity via NF-kappaB inactivation in stromal cells of ectopic endometrium","volume":"29","author":"Xiu-li","year":"2009","journal-title":"J Clin Immunol"},{"key":"10.1016\/j.ajpath.2023.04.007_bib55","doi-asserted-by":"crossref","first-page":"R162","DOI":"10.1152\/ajpregu.00649.2007","article-title":"Endometriosis as a neurovascular condition: estrous variations in innervation, vascularization, and growth factor content of ectopic endometrial cysts in the rat","volume":"294","author":"Zhang","year":"2008","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.ajpath.2023.04.007_bib56","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1093\/humupd\/dmaa008","article-title":"Brain-derived neurotrophic factor (BDNF) expression and function in the mammalian reproductive tract","volume":"26","author":"Chow","year":"2020","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.ajpath.2023.04.007_bib57","doi-asserted-by":"crossref","first-page":"271ra9","DOI":"10.1126\/scitranslmed.3010626","article-title":"Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis","volume":"7","author":"Zhao","year":"2015","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.ajpath.2023.04.007_bib58","doi-asserted-by":"crossref","first-page":"2286","DOI":"10.1016\/j.ajpath.2015.04.012","article-title":"Estradiol is a critical mediator of macrophage-nerve cross talk in peritoneal endometriosis","volume":"185","author":"Greaves","year":"2015","journal-title":"Am J Pathol"}],"container-title":["The American Journal of Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944023001645?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944023001645?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T16:42:56Z","timestamp":1757695376000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002944023001645"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":58,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["S0002944023001645"],"URL":"https:\/\/doi.org\/10.1016\/j.ajpath.2023.04.007","relation":{},"ISSN":["0002-9440"],"issn-type":[{"value":"0002-9440","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neurotrophins and Their Receptors, Novel Therapeutic Targets for Pelvic Pain in Endometriosis, Are Coordinately Regulated by IL-1\u03b2 via the JNK Signaling Pathway","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajpath.2023.04.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 American Society for Investigative Pathology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}