{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:21:18Z","timestamp":1792110078624,"version":"4.4.0"},"reference-count":146,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100006928","name":"Ohio State University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006928","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI148180"],"award-info":[{"award-number":["AI148180"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajp.amjpathol.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Pathology"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.ajpath.2024.06.004","type":"journal-article","created":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T15:55:25Z","timestamp":1721318125000},"page":"1807-1822","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Influenza, SARS-CoV-2, and Their Impact on Chronic Lung Diseases and Fibrosis"],"prefix":"10.1016","volume":"194","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2323-1245","authenticated-orcid":false,"given":"Sourabh","family":"Soni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Antonescu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaylin","family":"Ro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1505-2837","authenticated-orcid":false,"given":"Jeffrey C.","family":"Horowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5360-2158","authenticated-orcid":false,"given":"Yohannes A.","family":"Mebratu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8023-5680","authenticated-orcid":false,"given":"Richard S.","family":"Nho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajpath.2024.06.004_bib1","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1007\/s10096-020-03840-9","article-title":"Influenza and antiviral resistance: an overview","volume":"39","author":"Lampejo","year":"2020","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.ajpath.2024.06.004_bib2","first-page":"1057","article-title":"Estimates of deaths associated with seasonal influenza\u2014United States, 1976\u20132007","volume":"59","year":"2010","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.ajpath.2024.06.004_bib3","doi-asserted-by":"crossref","first-page":"5086","DOI":"10.1016\/j.vaccine.2007.03.046","article-title":"The annual impact of seasonal influenza in the US: measuring disease burden and costs","volume":"25","author":"Molinari","year":"2007","journal-title":"Vaccine"},{"key":"10.1016\/j.ajpath.2024.06.004_bib4","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1097\/MCP.0000000000000656","article-title":"Climate change and respiratory diseases: a 2020 perspective","volume":"26","author":"Joshi","year":"2020","journal-title":"Curr Opin Pulm Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib5","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0170561","article-title":"Quantification of pulmonary fibrosis in a bleomycin mouse model using automated histological image analysis","volume":"12","author":"Gilhodes","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.ajpath.2024.06.004_bib6","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/S2213-2600(20)30222-8","article-title":"Pulmonary fibrosis secondary to COVID-19: a call to arms?","volume":"8","author":"Spagnolo","year":"2020","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib7","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1001\/jama.2020.2648","article-title":"Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention","volume":"323","author":"Wu","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.ajpath.2024.06.004_bib8","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.ccm.2016.11.014","article-title":"Respiratory viral infections in chronic lung diseases","volume":"38","author":"Britto","year":"2017","journal-title":"Clin Chest Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib9","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1186\/s12967-021-03159-9","article-title":"Virus infection induced pulmonary fibrosis","volume":"19","author":"Huang","year":"2021","journal-title":"J Transl Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib10","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1016\/j.ajpath.2014.08.030","article-title":"The role of viral, host, and secondary bacterial factors in influenza pathogenesis","volume":"185","author":"Kash","year":"2015","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib11","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/S0140-6736(03)14630-2","article-title":"Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People\u2019s Republic of China, in February, 2003","volume":"362","author":"Zhong","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.ajpath.2024.06.004_bib12","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1056\/NEJMoa2001017","article-title":"A novel coronavirus from patients with pneumonia in China, 2019","volume":"382","author":"Zhu","year":"2020","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib13","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.chom.2016.01.007","article-title":"Dysregulated type I interferon and inflammatory monocyte-macrophage responses cause lethal pneumonia in SARS-CoV-infected mice","volume":"19","author":"Channappanavar","year":"2016","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.ajpath.2024.06.004_bib14","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s11262-010-0544-x","article-title":"SARS-CoV nucleocapsid protein antagonizes IFN-[beta] response by targeting initial step of IFN-[beta] induction pathway, and its C-terminal region is critical for the antagonism","volume":"42","author":"Lu","year":"2011","journal-title":"Virus Genes"},{"key":"10.1016\/j.ajpath.2024.06.004_bib15","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1183\/13993003.01282-2015","article-title":"Influenza virus damages the alveolar barrier by disrupting epithelial cell tight junctions","volume":"47","author":"Short","year":"2016","journal-title":"Eur Respir J"},{"key":"10.1016\/j.ajpath.2024.06.004_bib16","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S1473-3099(13)70286-X","article-title":"Pathogenesis of influenza-induced acute respiratory distress syndrome","volume":"14","author":"Short","year":"2014","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.ajpath.2024.06.004_bib17","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004053","article-title":"Alveolar macrophages are essential for protection from respiratory failure and associated morbidity following influenza virus infection","volume":"10","author":"Schneider","year":"2014","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.ajpath.2024.06.004_bib18","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.1172\/JCI124615","article-title":"The role of macrophages in the resolution of inflammation","volume":"129","author":"Watanabe","year":"2019","journal-title":"J Clin Invest"},{"key":"10.1016\/j.ajpath.2024.06.004_bib19","article-title":"PI3K\/Akt signaling pathway modulates influenza virus induced mouse alveolar macrophage polarization to M1\/M2b","volume":"9","author":"Zhao","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ajpath.2024.06.004_bib20","article-title":"Autophagy and exosome coordinately enhance macrophage M1 polarization and recruitment in influenza A virus infection","volume":"13","author":"Xia","year":"2022","journal-title":"Front Immunol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib21","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.1099\/jgv.0.000240","article-title":"Susceptibility of bone marrow-derived macrophages to influenza virus infection is dependent on macrophage phenotype","volume":"96","author":"Campbell","year":"2015","journal-title":"J Gen Virol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib22","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2021.670177","article-title":"NS1: a key protein in the \u201cgame: between influenza A virus and host in innate immunity","volume":"11","author":"Ji","year":"2021","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib23","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1159\/000484258","article-title":"Interferon-stimulated genes as enhancers of antiviral innate immune signaling","volume":"10","author":"Crosse","year":"2018","journal-title":"J Innate Immun"},{"key":"10.1016\/j.ajpath.2024.06.004_bib24","doi-asserted-by":"crossref","first-page":"320","DOI":"10.3389\/fimmu.2018.00320","article-title":"Host immune response to influenza a virus infection","volume":"9","author":"Chen","year":"2018","journal-title":"Front Immunol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib25","doi-asserted-by":"crossref","first-page":"9610","DOI":"10.1073\/pnas.1807516115","article-title":"Distinct antiviral signatures revealed by the magnitude and round of influenza virus replication in\u00a0vivo","volume":"115","author":"Sjaastad","year":"2018","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ajpath.2024.06.004_bib26","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1038\/s41580-021-00418-x","article-title":"Mechanisms of SARS-CoV-2 entry into cells","volume":"23","author":"Jackson","year":"2022","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib27","doi-asserted-by":"crossref","first-page":"5125","DOI":"10.3390\/ijms23095125","article-title":"Angiotensin II promotes SARS-CoV-2 infection via upregulation of ACE2 in human bronchial cells","volume":"23","author":"Caputo","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.ajpath.2024.06.004_bib28","first-page":"178","article-title":"Innate immune evasion strategies of SARS-CoV-2","volume":"21","author":"Minkoff","year":"2023","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib29","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1002\/jmv.27317","article-title":"The role of type I interferon in the treatment of COVID-19","volume":"94","author":"Sodeifian","year":"2022","journal-title":"J Med Virol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib30","doi-asserted-by":"crossref","first-page":"6243","DOI":"10.1016\/j.cell.2021.11.033","article-title":"SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis","volume":"184","author":"Wendisch","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.ajpath.2024.06.004_bib31","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1016\/j.chest.2019.10.032","article-title":"Viral infection increases the risk of idiopathic pulmonary fibrosis: a meta-analysis","volume":"157","author":"Sheng","year":"2020","journal-title":"Chest"},{"key":"10.1016\/j.ajpath.2024.06.004_bib32","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.02806-2021","article-title":"Acute exacerbation of idiopathic pulmonary fibrosis after SARS-CoV-2 vaccination","volume":"59","author":"Bando","year":"2022","journal-title":"Eur Respir J"},{"key":"10.1016\/j.ajpath.2024.06.004_bib33","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/s41421-020-0167-x","article-title":"Inflammasome activation and regulation: toward a better understanding of complex mechanisms","volume":"6","author":"Zheng","year":"2020","journal-title":"Cell Discov"},{"key":"10.1016\/j.ajpath.2024.06.004_bib34","doi-asserted-by":"crossref","DOI":"10.1126\/science.abd0811","article-title":"Human NLRP1 is a sensor for double-stranded RNA","volume":"371","author":"Bauernfried","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.ajpath.2024.06.004_bib35","doi-asserted-by":"crossref","DOI":"10.1038\/srep27912","article-title":"Reassessing the role of the NLRP3 inflammasome during pathogenic influenza a virus infection via temporal inhibition","volume":"6","author":"Tate","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.ajpath.2024.06.004_bib36","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1011014","article-title":"Respiratory viruses and the inflammasome: the double-edged sword of inflammation","volume":"18","author":"Waldstein","year":"2022","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.ajpath.2024.06.004_bib37","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/s41577-020-0331-4","article-title":"Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages","volume":"20","author":"Merad","year":"2020","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib39","doi-asserted-by":"crossref","first-page":"5501","DOI":"10.3390\/jcm12175501","article-title":"Advances in the relationship between respiratory viruses and asthma","volume":"12","author":"de Jes\u00fas Romero-Tapia","year":"2023","journal-title":"J Clin Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib40","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1097\/ACI.0000000000000101","article-title":"The evolution of the hygiene hypothesis: the role of early-life exposures to viruses and microbes and their relationship to asthma and allergic diseases","volume":"14","author":"Daley","year":"2014","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib41","doi-asserted-by":"crossref","first-page":"9914","DOI":"10.3390\/ijms23179914","article-title":"Viral infection and airway epithelial immunity in asthma","volume":"23","author":"Kim","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.ajpath.2024.06.004_bib42","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1001\/jama.2020.15654","article-title":"Dysanapsis and COPD\u2014reply","volume":"324","author":"Smith","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.ajpath.2024.06.004_bib43","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1513\/pats.2306030","article-title":"Role of viruses in exacerbations of chronic obstructive pulmonary disease","volume":"1","author":"Wedzicha","year":"2004","journal-title":"Proc Am Thorac Soc"},{"key":"10.1016\/j.ajpath.2024.06.004_bib44","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/S0140-6736(07)61382-8","article-title":"COPD exacerbations: defining their cause and prevention","volume":"370","author":"Wedzicha","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.ajpath.2024.06.004_bib45","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1164\/ajrccm.164.9.2105011","article-title":"Respiratory viruses, symptoms, and inflammatory markers in acute exacerbations and stable chronic obstructive pulmonary disease","volume":"164","author":"Seemungal","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib46","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/S2213-2600(20)30167-3","article-title":"Do chronic respiratory diseases or their treatment affect the risk of SARS-CoV-2 infection?","volume":"8","author":"Halpin","year":"2020","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib47","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.02108-2020","article-title":"COVID-19 and COPD","volume":"56","author":"Leung","year":"2020","journal-title":"Eur Respir J"},{"key":"10.1016\/j.ajpath.2024.06.004_bib48","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.chest.2020.03.032","article-title":"Comparison of hospitalized patients with ARDS caused by COVID-19 and H1N1","volume":"158","author":"Tang","year":"2020","journal-title":"Chest"},{"key":"10.1016\/j.ajpath.2024.06.004_bib49","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1042\/CS20210879","article-title":"Pathogenesis of pneumonia and acute lung injury","volume":"136","author":"Long","year":"2022","journal-title":"Clin Sci (Lond)"},{"key":"10.1016\/j.ajpath.2024.06.004_bib50","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1016\/j.cell.2020.11.032","article-title":"Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein","volume":"183","author":"Walls","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.ajpath.2024.06.004_bib51","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.cell.2020.02.052","article-title":"SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor","volume":"181","author":"Hoffmann","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.ajpath.2024.06.004_bib52","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/s41586-020-2196-x","article-title":"Virological assessment of hospitalized patients with COVID-2019","volume":"581","author":"W\u00f6lfel","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.ajpath.2024.06.004_bib53","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/S2213-2600(21)00218-6","article-title":"The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity","volume":"9","author":"Osuchowski","year":"2021","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib54","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1001\/jama.2020.6775","article-title":"Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area","volume":"323","author":"Richardson","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.ajpath.2024.06.004_bib55","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1183\/09031936.00186214","article-title":"Influenza virus-induced lung injury: pathogenesis and implications for treatment","volume":"45","author":"Herold","year":"2015","journal-title":"Eur Respir J"},{"key":"10.1016\/j.ajpath.2024.06.004_bib56","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1056\/NEJMra1608077","article-title":"Acute respiratory distress syndrome","volume":"377","author":"Thompson","year":"2017","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib57","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.abe4282","article-title":"Lung transplantation for patients with severe COVID-19","volume":"12","author":"Bharat","year":"2020","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib58","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1038\/s41586-020-03148-w","article-title":"Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia","volume":"590","author":"Grant","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.ajpath.2024.06.004_bib59","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1056\/NEJMra043184","article-title":"Cystic fibrosis","volume":"352","author":"Rowe","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib60","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1136\/thoraxjnl-2013-204000","article-title":"Incidence and clinical impact of respiratory viruses in adults with cystic fibrosis","volume":"69","author":"Flight","year":"2014","journal-title":"Thorax"},{"key":"10.1016\/j.ajpath.2024.06.004_bib61","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/nrg3849","article-title":"Cystic fibrosis genetics: from molecular understanding to clinical application","volume":"16","author":"Cutting","year":"2015","journal-title":"Nat Rev Genet"},{"key":"10.1016\/j.ajpath.2024.06.004_bib62","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.170022","article-title":"Influenza A-induced cystic fibrosis transmembrane conductance regulator dysfunction increases susceptibility to Streptococcus pneumoniae","volume":"8","author":"Earnhardt","year":"2023","journal-title":"JCI Insight"},{"key":"10.1016\/j.ajpath.2024.06.004_bib63","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/S2213-2600(16)30121-7","article-title":"Efficacy and safety of lumacaftor\/ivacaftor combination therapy in patients with cystic fibrosis homozygous for Phe508del CFTR by pulmonary function subgroup: a pooled analysis","volume":"4","author":"Elborn","year":"2016","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib64","doi-asserted-by":"crossref","first-page":"e35","DOI":"10.1016\/S2213-2600(20)30177-6","article-title":"Impact of COVID-19 on people with cystic fibrosis","volume":"8","author":"Colombo","year":"2020","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib65","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.arbres.2021.12.003","article-title":"The impact of COVID-19 in cystic fibrosis","volume":"58","author":"Flume","year":"2022","journal-title":"Arch Bronconeumol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib66","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ijid.2019.07.030","article-title":"Association between the risk of lung cancer and influenza: a population-based nested case-control study","volume":"88","author":"Weng","year":"2019","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.ajpath.2024.06.004_bib67","doi-asserted-by":"crossref","first-page":"3598","DOI":"10.3390\/cancers14153598","article-title":"Interactions between COVID-19 and lung cancer: lessons learned during the pandemic","volume":"14","author":"Bian","year":"2022","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.ajpath.2024.06.004_bib68","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000018035","article-title":"Effect of annual influenza vaccination on reducing lung cancer in patients with chronic obstructive pulmonary disease from a population-based cohort study","volume":"98","author":"Chen","year":"2019","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.ajpath.2024.06.004_bib69","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1073\/pnas.1904022116","article-title":"Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer","volume":"117","author":"Newman","year":"2020","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ajpath.2024.06.004_bib70","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.1164\/rccm.201506-1063ST","article-title":"An official ATS\/ERS\/JRS\/ALAT clinical practice guideline: treatment of idiopathic pulmonary fibrosis. An update of the 2011 clinical practice guideline","volume":"192","author":"Raghu","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib71","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1183\/09031936.00176807","article-title":"Apoptosis in lung injury and fibrosis","volume":"32","author":"Drakopanagiotakis","year":"2008","journal-title":"Eur Respir J"},{"key":"10.1016\/j.ajpath.2024.06.004_bib72","first-page":"43","article-title":"Mechanisms for the resolution of organ fibrosis","volume":"34","author":"Horowitz","year":"2019","journal-title":"Physiology (Bethesda)"},{"key":"10.1016\/j.ajpath.2024.06.004_bib73","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1513\/pats.200601-003TK","article-title":"Role of epithelial cells in idiopathic pulmonary fibrosis: from innocent targets to serial killers","volume":"3","author":"Selman","year":"2006","journal-title":"Proc Am Thorac Soc"},{"key":"10.1016\/j.ajpath.2024.06.004_bib74","doi-asserted-by":"crossref","first-page":"166","DOI":"10.2353\/ajpath.2010.100115","article-title":"2009 Pandemic influenza A (H1N1): pathology and pathogenesis of 100 fatal cases in the United States","volume":"177","author":"Shieh","year":"2010","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib75","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s11547-011-0740-3","article-title":"Post-ARDS pulmonary fibrosis in patients with H1N1 pneumonia: role of follow-up CT","volume":"117","author":"Mineo","year":"2012","journal-title":"Radiol Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib76","first-page":"85","article-title":"Combined pirfenidone, azithromycin and prednisolone in post-H1N1 ARDS pulmonary fibrosis","volume":"35","author":"Saha","year":"2018","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"10.1016\/j.ajpath.2024.06.004_bib77","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1007\/s10517-017-3678-1","article-title":"Study of SMAD-dependent signal pathway in the development of early pulmonary fibrosis in mice infected with influenza A\/H1N1 virus","volume":"162","author":"Shatskaya","year":"2017","journal-title":"Bull Exp Biol Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib78","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1165\/rcmb.2010-0460OC","article-title":"Influenza induces endoplasmic reticulum stress, caspase-12-dependent apoptosis, and c-Jun N-terminal kinase-mediated transforming growth factor-[beta] release in lung epithelial cells","volume":"46","author":"Roberson","year":"2012","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib79","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/j.it.2020.10.004","article-title":"Mechanisms of SARS-CoV-2 transmission and pathogenesis","volume":"41","author":"Harrison","year":"2020","journal-title":"Trends Immunol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib80","doi-asserted-by":"crossref","DOI":"10.1016\/S1473-3099(20)30582-X","article-title":"Lung fibrosis: an undervalued finding in COVID-19 pathological series","volume":"21","author":"Grillo","year":"2021","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.ajpath.2024.06.004_bib81","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/S2213-2600(20)30225-3","article-title":"Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy","volume":"8","author":"George","year":"2020","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib82","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s41030-023-00226-y","article-title":"Post-COVID-19 pulmonary fibrosis: facts-challenges and futures: a narrative review","volume":"9","author":"Duong-Quy","year":"2023","journal-title":"Pulm Ther"},{"key":"10.1016\/j.ajpath.2024.06.004_bib83","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.01217-2020","article-title":"Abnormal pulmonary function in COVID-19 patients at time of hospital discharge","volume":"55","author":"Mo","year":"2020","journal-title":"Eur Respir J"},{"key":"10.1016\/j.ajpath.2024.06.004_bib84","doi-asserted-by":"crossref","first-page":"350","DOI":"10.7326\/M20-2566","article-title":"Pulmonary arterial thrombosis in COVID-19 with fatal outcome: results from a prospective, single-center, clinicopathologic case series","volume":"173","author":"Lax","year":"2020","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib85","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1096\/fj.15-273953","article-title":"STAT-3 contributes to pulmonary fibrosis through epithelial injury and fibroblast-myofibroblast differentiation","volume":"30","author":"Pedroza","year":"2016","journal-title":"FASEB J"},{"key":"10.1016\/j.ajpath.2024.06.004_bib86","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1186\/s12931-020-01445-6","article-title":"SARS-CoV-2 induces transcriptional signatures in human lung epithelial cells that promote lung fibrosis","volume":"21","author":"Xu","year":"2020","journal-title":"Respir Res"},{"key":"10.1016\/j.ajpath.2024.06.004_bib87","doi-asserted-by":"crossref","first-page":"4327","DOI":"10.1021\/acs.jproteome.0c00387","article-title":"\"A chain only as strong as its weakest link\": an up-to-date literature review on the bidirectional interaction of pulmonary fibrosis and COVID-19","volume":"19","author":"Crisan-Dabija","year":"2020","journal-title":"J Proteome Res"},{"key":"10.1016\/j.ajpath.2024.06.004_bib88","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1038\/s41586-020-2324-7","article-title":"Respiratory disease in rhesus macaques inoculated with SARS-CoV-2","volume":"585","author":"Munster","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.ajpath.2024.06.004_bib89","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1164\/rccm.201006-0894CI","article-title":"Clinical course and prediction of survival in idiopathic pulmonary fibrosis","volume":"183","author":"Ley","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib90","doi-asserted-by":"crossref","first-page":"E177","DOI":"10.1148\/radiol.2021203153","article-title":"Six-month follow-up chest CT findings after severe COVID-19 pneumonia","volume":"299","author":"Han","year":"2021","journal-title":"Radiology"},{"key":"10.1016\/j.ajpath.2024.06.004_bib91","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1183\/09031936.00159709","article-title":"Acute exacerbation of idiopathic pulmonary fibrosis: incidence, risk factors and outcome","volume":"37","author":"Song","year":"2011","journal-title":"Eur Respir J"},{"key":"10.1016\/j.ajpath.2024.06.004_bib92","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1164\/rccm.200703-463PP","article-title":"Acute exacerbations of idiopathic pulmonary fibrosis","volume":"176","author":"Collard","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib93","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1111\/j.1440-1843.2010.01774.x","article-title":"A detailed evaluation of acute respiratory decline in patients with fibrotic lung disease: aetiology and outcomes","volume":"15","author":"Huie","year":"2010","journal-title":"Respirology"},{"key":"10.1016\/j.ajpath.2024.06.004_bib94","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1164\/rccm.201010-1752OC","article-title":"Viral infection in acute exacerbation of idiopathic pulmonary fibrosis","volume":"183","author":"Wootton","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib95","article-title":"The role of herpes viruses in pulmonary fibrosis","volume":"8","author":"Duckworth","year":"2021","journal-title":"Front Med (Lausanne)"},{"key":"10.1016\/j.ajpath.2024.06.004_bib96","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/s41392-022-01251-0","article-title":"Aging and aging-related diseases: from molecular mechanisms to interventions and treatments","volume":"7","author":"Guo","year":"2022","journal-title":"Signal Transduct Target Ther"},{"key":"10.1016\/j.ajpath.2024.06.004_bib97","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2020.563850","article-title":"Innate immunity and influenza a virus pathogenesis: lessons for COVID-19","volume":"10","author":"Hartshorn","year":"2020","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib98","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s00268-003-7397-6","article-title":"Aging and wound healing","volume":"28","author":"Gosain","year":"2004","journal-title":"World J Surg"},{"key":"10.1016\/j.ajpath.2024.06.004_bib99","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.2169\/internalmedicine.49.3890","article-title":"Acute exacerbation of idiopathic pulmonary fibrosis after pandemic influenza A (H1N1) vaccination","volume":"49","author":"Umeda","year":"2010","journal-title":"Intern Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib100","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.trsl.2021.09.001","article-title":"From ARDS to pulmonary fibrosis: the next phase of the COVID-19 pandemic?","volume":"241","author":"Michalski","year":"2022","journal-title":"Transl Res"},{"key":"10.1016\/j.ajpath.2024.06.004_bib101","doi-asserted-by":"crossref","DOI":"10.1016\/j.exger.2021.111507","article-title":"Aging & COVID-19 susceptibility, disease severity, and clinical outcomes: the role of entangled risk factors","volume":"154","author":"Farshbafnadi","year":"2021","journal-title":"Exp Gerontol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib102","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.add4853","article-title":"Respiratory mucosal immunity against SARS-CoV-2 after mRNA vaccination","volume":"7","author":"Tang","year":"2022","journal-title":"Sci Immunol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib103","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1177\/23971983221143252","article-title":"COVID-19 and protection of vaccination in patients with systemic sclerosis-associated interstitial lung disease","volume":"8","author":"Panopoulos","year":"2023","journal-title":"J Scleroderma Relat Disord"},{"key":"10.1016\/j.ajpath.2024.06.004_bib104","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1164\/rccm.201807-1237OC","article-title":"The long noncoding RNA DNM3OS Is a reservoir of FibromiRs with major functions in lung fibroblast response to TGF-[beta] and pulmonary fibrosis","volume":"200","author":"Savary","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib105","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1038\/s41392-022-01070-3","article-title":"Targeting fibrosis: mechanisms and clinical trials","volume":"7","author":"Zhao","year":"2022","journal-title":"Signal Transduct Target Ther"},{"key":"10.1016\/j.ajpath.2024.06.004_bib106","doi-asserted-by":"crossref","first-page":"7849","DOI":"10.3390\/ijms24097849","article-title":"Efficacy of pirfenidone and nintedanib in interstitial lung diseases other than idiopathic pulmonary fibrosis: a systematic review","volume":"24","author":"Amati","year":"2023","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.ajpath.2024.06.004_bib107","article-title":"Retracted and republished from: \u201cThe current state of research on influenza antiviral drug development: drugs in clinical trial and licensed drugs.\u201d","volume":"15","author":"Li","year":"2024","journal-title":"mBio"},{"key":"10.1016\/j.ajpath.2024.06.004_bib108","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2022.114189","article-title":"Influenza-existing drugs and treatment prospects","volume":"232","author":"Sarker","year":"2022","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.ajpath.2024.06.004_bib109","article-title":"Targeting growth factor and cytokine pathways to treat idiopathic pulmonary fibrosis","volume":"13","author":"Ma","year":"2022","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib110","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/bcpt.13533","article-title":"Camostat mesylate against SARS-CoV-2 and COVID-19-rationale, dosing and safety","volume":"128","author":"Breining","year":"2021","journal-title":"Basic Clin Pharmacol Toxicol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib111","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/s41573-023-00672-y","article-title":"Therapeutic strategies for COVID-19: progress and lessons learned","volume":"22","author":"Li","year":"2023","journal-title":"Nat Rev Drug Discov"},{"key":"10.1016\/j.ajpath.2024.06.004_bib112","doi-asserted-by":"crossref","first-page":"51","DOI":"10.3390\/jpm14010051","article-title":"Perspectives on post-COVID-19 pulmonary fibrosis treatment","volume":"14","author":"Cojocaru","year":"2023","journal-title":"J Pers Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib113","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1143158","article-title":"Pharmacological approaches to pulmonary fibrosis following COVID-19","volume":"14","author":"Lassan","year":"2023","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib114","doi-asserted-by":"crossref","first-page":"104","DOI":"10.5005\/jp-journals-10071-23709","article-title":"Post-COVID-19 pulmonary fibrosis: a lifesaving challenge","volume":"25","author":"Prakash","year":"2021","journal-title":"Indian J Crit Care Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib115","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2022.812199","article-title":"HSP90 inhibitors modulate SARS-CoV-2 spike protein subunit 1-induced human pulmonary microvascular endothelial activation and barrier dysfunction","volume":"13","author":"Colunga Biancatelli","year":"2022","journal-title":"Front Physiol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib116","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.3390\/cells11061046","article-title":"The heat shock protein 90 inhibitor, AT13387, protects the alveolo-capillary barrier and prevents HCl-induced\u00a0chronic lung injury and pulmonary fibrosis","volume":"11","author":"Colunga Biancatelli","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.ajpath.2024.06.004_bib117","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/s13770-023-00525-0","article-title":"Immunomodulation for tissue repair and regeneration","volume":"20","author":"Moon","year":"2023","journal-title":"Tissue Eng Regen Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib118","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/s41392-023-01452-1","article-title":"Macrophages in immunoregulation and therapeutics","volume":"8","author":"Chen","year":"2023","journal-title":"Signal Transduct Target Ther"},{"key":"10.1016\/j.ajpath.2024.06.004_bib119","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/s41392-022-01230-5","article-title":"CD147 contributes to SARS-CoV-2-induced pulmonary fibrosis","volume":"7","author":"Wu","year":"2022","journal-title":"Signal Transduct Target Ther"},{"key":"10.1016\/j.ajpath.2024.06.004_bib120","doi-asserted-by":"crossref","first-page":"3818","DOI":"10.1038\/s41467-021-24007-w","article-title":"SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals","volume":"12","author":"Gassen","year":"2021","journal-title":"Nat Commun"},{"key":"10.1016\/j.ajpath.2024.06.004_bib121","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1056\/NEJMoa1402584","article-title":"Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis","volume":"370","author":"Richeldi","year":"2014","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib122","doi-asserted-by":"crossref","DOI":"10.15420\/cfr.2021.30","article-title":"Pirfenidone for idiopathic pulmonary fibrosis and beyond","volume":"8","author":"Aimo","year":"2022","journal-title":"Card Fail Rev"},{"key":"10.1016\/j.ajpath.2024.06.004_bib123","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1164\/rccm.201503-0562OC","article-title":"Efficacy of nintedanib in idiopathic pulmonary fibrosis across prespecified subgroups in INPULSIS","volume":"193","author":"Costabel","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib124","article-title":"Senotherapeutics: an emerging approach to the treatment of viral infectious diseases in the elderly","volume":"13","author":"Li","year":"2023","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib125","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1038\/s41586-021-03995-1","article-title":"Virus-induced senescence is a driver and therapeutic target in COVID-19","volume":"599","author":"Lee","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.ajpath.2024.06.004_bib126","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/s12985-023-02069-0","article-title":"Role and clinical implication of autophagy in COVID-19","volume":"20","author":"Shan","year":"2023","journal-title":"Virol J"},{"key":"10.1016\/j.ajpath.2024.06.004_bib127","article-title":"Therapeutic applications of mesenchymal stem cells in idiopathic pulmonary fibrosis","volume":"9","author":"Yang","year":"2021","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib128","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1513\/AnnalsATS.201604-277ED","article-title":"The global emergence of unregulated stem cell treatments for respiratory diseases. Professional societies need to act","volume":"13","author":"Ikonomou","year":"2016","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.ajpath.2024.06.004_bib129","doi-asserted-by":"crossref","first-page":"8196","DOI":"10.3390\/ijms23158196","article-title":"Immunomodulation of mesenchymal stem cells in acute lung injury: from preclinical animal models to treatment of severe COVID-19","volume":"23","author":"Li","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.ajpath.2024.06.004_bib130","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1093\/stcltm\/szad094","article-title":"Mesenchymal stem cells-derived exosomes alleviate acute lung injury by inhibiting alveolar macrophage pyroptosis","volume":"13","author":"Liu","year":"2024","journal-title":"Stem Cells Transl Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib131","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2023.176148","article-title":"Mesenchymal stem cells ameliorate H9N2-induced acute lung injury by inhibiting caspase-3-GSDME-mediated pyroptosis of lung alveolar epithelial cells","volume":"960","author":"Zhang","year":"2023","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.ajpath.2024.06.004_bib132","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1186\/s13287-021-02469-5","article-title":"Human umbilical cord mesenchymal stromal cells attenuate pulmonary fibrosis via regulatory T cell through interaction with macrophage","volume":"12","author":"Tang","year":"2021","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.ajpath.2024.06.004_bib133","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1002\/stem.3354","article-title":"Mesenchymal stem cell immunomodulation: in pursuit of controlling COVID-19 related cytokine storm","volume":"39","author":"Song","year":"2021","journal-title":"Stem Cells"},{"key":"10.1016\/j.ajpath.2024.06.004_bib134","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1186\/s13287-022-03181-8","article-title":"Stem cell-based therapy for pulmonary fibrosis","volume":"13","author":"Cheng","year":"2022","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.ajpath.2024.06.004_bib135","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1513\/AnnalsATS.202112-1359OC","article-title":"Effects of influenza vaccination in patients with interstitial lung diseases: an epidemiological claims data analysis","volume":"19","author":"Marijic","year":"2022","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.ajpath.2024.06.004_bib136","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.3390\/jcm11092437","article-title":"Importance of vaccination against SARS-CoV-2 in patients with interstitial lung disease associated with systemic autoimmune disease","volume":"11","author":"Mena-V\u00e1zquez","year":"2022","journal-title":"J Clin Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib137","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1038\/s41591-022-01908-x","article-title":"Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2","volume":"28","author":"Hagey","year":"2022","journal-title":"Nat Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib139","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1056\/NEJMoa1716197","article-title":"Baloxavir marboxil for uncomplicated influenza in adults and adolescents","volume":"379","author":"Hayden","year":"2018","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib141","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1177\/135965350701200302","article-title":"Amantadine-oseltamivir combination therapy for H5N1 influenza virus infection in mice","volume":"12","author":"Ilyushina","year":"2007","journal-title":"Antivir Ther"},{"key":"10.1016\/j.ajpath.2024.06.004_bib142","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1128\/AAC.00933-09","article-title":"Effects of the combination of favipiravir (T-705) and oseltamivir on influenza A virus infections in mice","volume":"54","author":"Smee","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ajpath.2024.06.004_bib143","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2022.101484","article-title":"Favipiravir, camostat, and ciclesonide combination therapy in patients with moderate COVID-19 pneumonia with\/without oxygen therapy: an open-label, single-center phase 3 randomized clinical trial","volume":"49","author":"Terada","year":"2022","journal-title":"EClinicalMedicine"},{"key":"10.1016\/j.ajpath.2024.06.004_bib144","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.ijid.2020.10.069","article-title":"Role of favipiravir in the treatment of COVID-19","volume":"102","author":"Joshi","year":"2021","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.ajpath.2024.06.004_bib145","doi-asserted-by":"crossref","first-page":"3545","DOI":"10.3390\/jcm10163545","article-title":"Ciclesonide inhaler treatment for mild-to-moderate COVID-19: a randomized, open-label, phase 2 trial","volume":"10","author":"Song","year":"2021","journal-title":"J Clin Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib146","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1164\/rccm.200610-1426OC","article-title":"Control of virus reactivation arrests pulmonary herpesvirus-induced fibrosis in IFN-gamma receptor-deficient mice","volume":"175","author":"Mora","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.ajpath.2024.06.004_bib147","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.114640","article-title":"Lung mesenchymal cells from patients with COVID-19 driven lung fibrosis: several features with CTD-ILD derived cells but with higher response to fibrogenic signals and might be more pro-inflammatory","volume":"162","author":"Bozzini","year":"2023","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.ajpath.2024.06.004_bib148","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1093\/qjmed\/hcad092","article-title":"Pulmonary fibrosis in COVID-19: mechanisms, consequences and targets","volume":"116","author":"O\u2019Reilly","year":"2023","journal-title":"QJM"},{"key":"10.1016\/j.ajpath.2024.06.004_bib149","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1093\/nsr\/nwaa041","article-title":"Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients","volume":"7","author":"Zhou","year":"2020","journal-title":"Natl Sci Rev"}],"container-title":["The American Journal of Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944024002359?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002944024002359?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:20:02Z","timestamp":1759332002000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002944024002359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":146,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["S0002944024002359"],"URL":"https:\/\/doi.org\/10.1016\/j.ajpath.2024.06.004","relation":{},"ISSN":["0002-9440"],"issn-type":[{"value":"0002-9440","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influenza, SARS-CoV-2, and Their Impact on Chronic Lung Diseases and Fibrosis","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajpath.2024.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 American Society for Investigative Pathology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}