{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T21:18:58Z","timestamp":1787692738541,"version":"build-2784847793"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T00:00:00Z","timestamp":1774396800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004325","name":"AstraZeneca PLC","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Preventive Cardiology"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.ajpc.2026.101583","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T16:26:05Z","timestamp":1774628765000},"page":"101583","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Novel risk model for predicting incident atrial fibrillation in patients taking \u03c9\u22123 fatty acid: sub-analysis of the STRENGTH randomized trial"],"prefix":"10.1016","volume":"28","author":[{"given":"Tom Kai Ming","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"Nicholls","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clement","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Becky Yi-Wen","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathy","family":"Wolski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"St John","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7231-6464","authenticated-orcid":false,"given":"Steven E","family":"Nissen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"17","key":"10.1016\/j.ajpc.2026.101583_bib0001","first-page":"1678","article-title":"Cardiovascular risk reduction with Icosapent ethyl. Reply","volume":"380","author":"Bhatt","year":"2019","journal-title":"N Engl J Med"},{"issue":"9567","key":"10.1016\/j.ajpc.2026.101583_bib0002","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/S0140-6736(07)60527-3","article-title":"Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis","volume":"369","author":"Yokoyama","year":"2007","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.ajpc.2026.101583_bib0003","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1161\/CIRCULATIONAHA.120.052209","article-title":"Effects of n-3 fatty acid supplements in elderly patients after myocardial infarction: a randomized, controlled trial","volume":"143","author":"Kalstad","year":"2021","journal-title":"Circulation."},{"issue":"1","key":"10.1016\/j.ajpc.2026.101583_bib0004","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1056\/NEJMoa1811403","article-title":"Marine n-3 fatty acids and prevention of cardiovascular disease and Cancer","volume":"380","author":"Manson","year":"2019","journal-title":"N Engl J Med"},{"issue":"22","key":"10.1016\/j.ajpc.2026.101583_bib0005","doi-asserted-by":"crossref","first-page":"2268","DOI":"10.1001\/jama.2020.22258","article-title":"Effect of high-dose \u03c9\u22123 fatty acids vs corn oil on major adverse cardiovascular events in patients at high cardiovascular risk: the STRENGTH randomized clinical trial","volume":"324","author":"Nicholls","year":"2020","journal-title":"JAMA"},{"issue":"8","key":"10.1016\/j.ajpc.2026.101583_bib0006","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1001\/jamacardio.2021.1157","article-title":"Association between achieved \u03c9\u22123 fatty acid levels and major adverse cardiovascular outcomes in patients with high cardiovascular risk: a secondary analysis of the STRENGTH trial","volume":"6","author":"Nissen","year":"2021","journal-title":"JAMA Cardiol"},{"issue":"2","key":"10.1016\/j.ajpc.2026.101583_bib0007","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.eprac.2024.09.016","article-title":"American Association of Clinical Endocrinology Clinical Practice Guideline on Pharmacologic management of adults with dyslipidemia","volume":"31","author":"Patel","year":"2025","journal-title":"Endocr Pract"},{"issue":"11 Suppl. 1","key":"10.1016\/j.ajpc.2026.101583_bib0008","first-page":"e1","article-title":"[2025 Focused Update of the 2019 ESC\/EAS Guidelines for the management of dyslipidaemias]","volume":"26","author":"Mach","year":"2025","journal-title":"G Ital Cardiol (Rome)"},{"issue":"25","key":"10.1016\/j.ajpc.2026.101583_bib0009","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1161\/CIRCULATIONAHA.121.055654","article-title":"Effect of long-term marine \u0277-3 fatty acids supplementation on the risk of atrial fibrillation in randomized controlled trials of cardiovascular outcomes: a systematic review and meta-analysis","volume":"144","author":"Gencer","year":"2021","journal-title":"Circulation"},{"issue":"11","key":"10.1016\/j.ajpc.2026.101583_bib0010","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1001\/jama.2021.1489","article-title":"Effect of marine \u03c9\u22123 fatty acid and vitamin D supplementation on incident atrial fibrillation: a randomized clinical trial","volume":"325","author":"Albert","year":"2021","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.ajpc.2026.101583_bib0011","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1161\/CIR.0000000000001193","article-title":"2023 ACC\/AHA\/ACCP\/HRS Guideline for the Diagnosis and Management of atrial fibrillation: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"149","author":"Joglar","year":"2024","journal-title":"Circulation"},{"issue":"36","key":"10.1016\/j.ajpc.2026.101583_bib0012","doi-asserted-by":"crossref","first-page":"3314","DOI":"10.1093\/eurheartj\/ehae176","article-title":"2024 ESC guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"45","author":"Van Gelder","year":"2024","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ajpc.2026.101583_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.atherosclerosis.2025.120228","article-title":"Differential cardiovascular impact of \u03c9\u22123 fatty acid in patients at high cardiovascular risk in Asians versus non-Asians: sub-analysis of the strength randomized clinical trial","volume":"408","author":"Wang","year":"2025","journal-title":"Atherosclerosis"},{"issue":"1","key":"10.1016\/j.ajpc.2026.101583_bib0017","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.recesp.2023.05.002","article-title":"Heart failure in older patients with atrial fibrillation: incidence and risk factors","volume":"77","author":"Melendo-Viu","year":"2024","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"issue":"8","key":"10.1016\/j.ajpc.2026.101583_bib32","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1001\/jamainternmed.2016.2925","article-title":"\u03c9\u22123 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease: Pooling Project of 19 Cohort Studies","volume":"176","author":"Del Gobbo","year":"2016","journal-title":"JAMA Intern Med"},{"issue":"Pt 1","key":"10.1016\/j.ajpc.2026.101583_bib0020","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1107\/S2052252521013488","article-title":"TRPV1 and Piezo: the 2021 Nobel Prize in Physiology or Medicine","volume":"9","author":"Cheng","year":"2022","journal-title":"IUCrJ"},{"issue":"14","key":"10.1016\/j.ajpc.2026.101583_bib0021","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1161\/CIRCULATIONAHA.121.058596","article-title":"Fishing for links between \u03c9\u22123 fatty acids and atrial fibrillation","volume":"145","author":"Fatkin","year":"2022","journal-title":"Circulation"},{"issue":"9665","key":"10.1016\/j.ajpc.2026.101583_bib0022","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S0140-6736(09)60443-8","article-title":"Development of a risk score for atrial fibrillation (Framingham Heart Study): a community-based cohort study","volume":"373","author":"Schnabel","year":"2009","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.ajpc.2026.101583_bib0023","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1038\/s41569-022-00820-8","article-title":"Epidemiology and modifiable risk factors for atrial fibrillation","volume":"20","author":"Elliott","year":"2023","journal-title":"Nat Rev Cardiol"},{"issue":"1","key":"10.1016\/j.ajpc.2026.101583_bib0024","doi-asserted-by":"crossref","first-page":"H86","DOI":"10.1152\/ajpheart.00010.2012","article-title":"Conduction and refractory disorders in the diabetic atrium","volume":"303","author":"Watanabe","year":"2012","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.ajpc.2026.101583_bib0025","doi-asserted-by":"crossref","first-page":"2189","DOI":"10.2147\/DMSO.S300616","article-title":"Diabetes mellitus promotes atrial structural remodeling and PARP-1\/ikkalpha\/NF-kappaB pathway activation in mice","volume":"14","author":"Meng","year":"2021","journal-title":"Diabetes Metab Syndr Obes"},{"issue":"1","key":"10.1016\/j.ajpc.2026.101583_bib0026","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/cvr\/cvu176","article-title":"Glucose fluctuations increase the incidence of atrial fibrillation in diabetic rats","volume":"104","author":"Saito","year":"2014","journal-title":"Cardiovasc Res"},{"issue":"5","key":"10.1016\/j.ajpc.2026.101583_bib0027","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1093\/advances\/nmaa029","article-title":"Fish consumption and the risk of chronic disease: an umbrella review of meta-analyses of prospective cohort studies","volume":"11","author":"Jayedi","year":"2020","journal-title":"Adv Nutr"},{"issue":"12","key":"10.1016\/j.ajpc.2026.101583_bib0028","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1161\/CIRCEP.123.012334","article-title":"Risk factors for the development of new-onset persistent atrial fibrillation: subanalysis of the VITAL study","volume":"16","author":"Middeldorp","year":"2023","journal-title":"Circ Arrhythm Electrophysiol"}],"container-title":["American Journal of Preventive Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666667726001777?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666667726001777?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T20:28:03Z","timestamp":1787689683000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666667726001777"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":24,"alternative-id":["S2666667726001777"],"URL":"https:\/\/doi.org\/10.1016\/j.ajpc.2026.101583","relation":{},"ISSN":["2666-6677"],"issn-type":[{"value":"2666-6677","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Novel risk model for predicting incident atrial fibrillation in patients taking \u03c9\u22123 fatty acid: sub-analysis of the STRENGTH randomized trial","name":"articletitle","label":"Article Title"},{"value":"American Journal of Preventive Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajpc.2026.101583","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101583"}}