{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T05:25:29Z","timestamp":1793424329322,"version":"4.5.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["CP18\/00073"],"award-info":[{"award-number":["CP18\/00073"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI19\/01300"],"award-info":[{"award-number":["PI19\/01300"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PIE13\/00045"],"award-info":[{"award-number":["PIE13\/00045"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["amjtransplant.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Transplantation"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.ajt.2023.07.009","type":"journal-article","created":{"date-parts":[[2023,7,20]],"date-time":"2023-07-20T04:41:53Z","timestamp":1689828113000},"page":"1949-1960","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["A joint program of antimicrobial stewardship and hospital-acquired infection control to reduce healthcare-associated infections after kidney transplantation: The Hipomenes study"],"prefix":"10.1016","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8765-3466","authenticated-orcid":false,"given":"Jos\u00e9 Tiago","family":"Silva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Montoro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1578-2909","authenticated-orcid":false,"given":"Mar\u00eda Asunci\u00f3n","family":"P\u00e9rez-Jacoiste As\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0315-8001","authenticated-orcid":false,"given":"Mario","family":"Fern\u00e1ndez-Ruiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Polanco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Manuel","family":"Caro-Teller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0238-1364","authenticated-orcid":false,"given":"Amado","family":"Andr\u00e9s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9520-8255","authenticated-orcid":false,"given":"Jos\u00e9 Mar\u00eda","family":"Aguado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5333-7529","authenticated-orcid":false,"given":"Francisco","family":"L\u00f3pez-Medrano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"20","key":"10.1016\/j.ajt.2023.07.009_bib1","doi-asserted-by":"crossref","first-page":"409","DOI":"10.21037\/atm.2018.09.68","article-title":"Solid organ transplantation in the 21st century","volume":"6","author":"Black","year":"2018","journal-title":"Ann Transl Med"},{"issue":"2","key":"10.1016\/j.ajt.2023.07.009_bib2","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.rcl.2015.09.008","article-title":"Interventional and surgical techniques in solid organ transplantation","volume":"54","author":"Ingraham","year":"2016","journal-title":"Radiol Clin North Am"},{"issue":"1","key":"10.1016\/j.ajt.2023.07.009_bib3","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.ccc.2008.12.001","article-title":"History of solid organ transplantation and organ donation","volume":"25","author":"Linden","year":"2009","journal-title":"Crit Care Clin"},{"issue":"3","key":"10.1016\/j.ajt.2023.07.009_bib4","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.trre.2016.04.001","article-title":"Management of cytomegalovirus infection in solid organ transplant recipients: SET\/GESITRA-SEIMC\/REIPI recommendations","volume":"30","author":"Torre-Cisneros","year":"2016","journal-title":"Transplant Rev (Orlando)"},{"issue":"suppl 1","key":"10.1016\/j.ajt.2023.07.009_bib5","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.cmi.2018.01.002","article-title":"Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline","volume":"24","author":"Ullmann","year":"2018","journal-title":"Clin Microbiol Infect"},{"issue":"9","key":"10.1016\/j.ajt.2023.07.009_bib6","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.13513","volume":"33","author":"Subramanian","year":"2019","journal-title":"Clin Transplant"},{"issue":"suppl 7","key":"10.1016\/j.ajt.2023.07.009_bib7","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/1469-0691.12687","article-title":"Multidrug-resistant bacteria in solid organ transplant recipients","volume":"20","author":"Cervera","year":"2014","journal-title":"Clin Microbiol Infect"},{"issue":"3","key":"10.1016\/j.ajt.2023.07.009_bib8","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.idc.2018.04.004","article-title":"Multidrug-resistant bacterial infections in solid organ transplant candidates and recipients","volume":"32","author":"Bartoletti","year":"2018","journal-title":"Infect Dis Clin North Am"},{"issue":"4","key":"10.1016\/j.ajt.2023.07.009_bib9","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1097\/QCO.0b013e328354f192","article-title":"Losing ground: multidrug-resistant bacteria in solid-organ transplantation","volume":"25","author":"Herati","year":"2012","journal-title":"Curr Opin Infect Dis"},{"issue":"4","key":"10.1016\/j.ajt.2023.07.009_bib10","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/tid.12547","article-title":"Progressive increase of resistance in Enterobacteriaceae urinary isolates from kidney transplant recipients over the past decade: narrowing of the therapeutic options","volume":"18","author":"Orig\u00fcen","year":"2016","journal-title":"Transpl Infect Dis"},{"issue":"4","key":"10.1016\/j.ajt.2023.07.009_bib11","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1097\/MOT.0000000000000890","article-title":"New drugs for difficult bugs: management of multidrug-resistant gram-negative infections in solid organ transplant recipients","volume":"26","author":"Pouch","year":"2021","journal-title":"Curr Opin Organ Transplant"},{"issue":"6","key":"10.1016\/j.ajt.2023.07.009_bib12","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1097\/QCO.0000000000000488","article-title":"Multidrug-resistant Gram-negative infection in solid organ transplant recipients: implications for outcome and treatment","volume":"31","author":"Silva","year":"2018","journal-title":"Curr Opin Infect Dis"},{"issue":"4","key":"10.1016\/j.ajt.2023.07.009_bib13","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1097\/QCO.0000000000000075","article-title":"Clostridium difficile infection in solid organ transplant recipients","volume":"27","author":"Honda","year":"2014","journal-title":"Curr Opin Infect Dis"},{"issue":"4","key":"10.1016\/j.ajt.2023.07.009_bib14","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1097\/MOT.0000000000000430","article-title":"Clostridium difficile infection in solid organ transplant recipients","volume":"22","author":"Nanayakkara","year":"2017","journal-title":"Curr Opin Organ Transplant"},{"issue":"4","key":"10.1016\/j.ajt.2023.07.009_bib15","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s15010-015-0737-2","article-title":"Potential role of post-transplant hypogammaglobulinemia in the risk of Clostridium difficile infection after kidney transplantation: a case-control study","volume":"43","author":"Orig\u00fcen","year":"2015","journal-title":"Infection"},{"issue":"6","key":"10.1016\/j.ajt.2023.07.009_bib16","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.12968","article-title":"Epidemiology, risk factors, and outcome of Clostridium difficile infection in heart and heart-lung transplant recipients","volume":"31","author":"Bruminhent","year":"2017","journal-title":"Clin Transplant"},{"issue":"1","key":"10.1016\/j.ajt.2023.07.009_bib17","doi-asserted-by":"crossref","DOI":"10.1111\/tid.13770","article-title":"Clostridioides difficile infection in solid organ and hematopoietic stem cell transplant recipients: A prospective multinational study","volume":"24","author":"Blumberg","year":"2022","journal-title":"Transpl Infect Dis"},{"issue":"9","key":"10.1016\/j.ajt.2023.07.009_bib18","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1111\/ajt.12364","article-title":"Call for antimicrobial stewardship in solid organ transplantation","volume":"13","author":"Aitken","year":"2013","journal-title":"Am J Transplant"},{"issue":"4","key":"10.1016\/j.ajt.2023.07.009_bib19","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1097\/MOT.0000000000000886","article-title":"The time is now: antimicrobial stewardship in solid organ transplantation","volume":"26","author":"Hand","year":"2021","journal-title":"Curr Opin Organ Transplant"},{"issue":"1","key":"10.1016\/j.ajt.2023.07.009_bib20","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/ajt.16743","article-title":"White paper on antimicrobial stewardship in solid organ transplant recipients","volume":"22","author":"So","year":"2022","journal-title":"Am J Transplant"},{"issue":"4","key":"10.1016\/j.ajt.2023.07.009_bib21","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1097\/QCO.0000000000000380","article-title":"Feasibility and applicability of antimicrobial stewardship in immunocompromised patients","volume":"30","author":"Robilotti","year":"2017","journal-title":"Curr Opin Infect Dis"},{"issue":"12","key":"10.1016\/j.ajt.2023.07.009_bib22","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1017\/ice.2016.213","article-title":"Impact of an infection control and antimicrobial stewardship program on solid organ transplantation and hepatobiliary surgical site infections","volume":"37","author":"Frenette","year":"2016","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"7","key":"10.1016\/j.ajt.2023.07.009_bib23","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1111\/myc.13098","article-title":"How can we optimise antifungal use in a solid organ transplant centre? Local epidemiology and antifungal stewardship implementation: A single-centre study","volume":"63","author":"Mularoni","year":"2020","journal-title":"Mycoses"},{"issue":"1","key":"10.1016\/j.ajt.2023.07.009_bib24","doi-asserted-by":"crossref","first-page":"e72","DOI":"10.1017\/ash.2022.53","article-title":"Bring it on: top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them","volume":"2","author":"So","year":"2022","journal-title":"Antimicrob Steward Healthc Epidemiol"},{"key":"10.1016\/j.ajt.2023.07.009_bib25","series-title":"Hand hygiene technical reference manual: to be used by health-care workers, trainers and observers of hand hygiene practices","year":"2009"},{"issue":"3","key":"10.1016\/j.ajt.2023.07.009_bib27","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","article-title":"Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance","volume":"18","author":"Magiorakos","year":"2012","journal-title":"Clin Microbiol Infect"},{"issue":"7","key":"10.1016\/j.ajt.2023.07.009_bib28","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1164\/rccm.201908-1581ST","article-title":"Diagnosis and treatment of adults with community-acquired pneumonia. An official clinical practice guideline of the American Thoracic Society and Infectious Diseases Society of America","volume":"200","author":"Metlay","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"10.1016\/j.ajt.2023.07.009_bib29","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.eimc.2016.11.005","article-title":"Executive summary of the diagnosis and treatment of urinary tract infection: guidelines of the Spanish Society of Clinical Microbiology and Infectious Diseases (SEIMC)","volume":"35","author":"de Cueto","year":"2017","journal-title":"Enferm Infecc Microbiol Clin"},{"issue":"9","key":"10.1016\/j.ajt.2023.07.009_bib30","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/S1473-3099(17)30325-0","article-title":"Effect of antibiotic stewardship on the incidence of infection and colonisation with antibiotic-resistant bacteria and Clostridium difficile infection: a systematic review and meta-analysis","volume":"17","author":"Baur","year":"2017","journal-title":"Lancet Infect Dis"},{"issue":"5","key":"10.1016\/j.ajt.2023.07.009_bib31","doi-asserted-by":"crossref","DOI":"10.1111\/tid.13883","article-title":"Antimicrobial stewardship in solid organ transplant recipients: current challenges and proposed metrics","volume":"24","author":"Raglow","year":"2022","journal-title":"Transpl Infect Dis"},{"issue":"5","key":"10.1016\/j.ajt.2023.07.009_bib32","doi-asserted-by":"crossref","DOI":"10.1111\/tid.13905","article-title":"Auditing tools for antimicrobial prescribing in solid organ transplant recipients: the why, the how, and an assessment of current options","volume":"24","author":"So","year":"2022","journal-title":"Transpl Infect Dis"},{"issue":"6","key":"10.1016\/j.ajt.2023.07.009_bib33","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1111\/ctr.12733","article-title":"Solid organ transplant patients: are there opportunities for antimicrobial stewardship?","volume":"30","author":"So","year":"2016","journal-title":"Clin Transplant"},{"issue":"4","key":"10.1016\/j.ajt.2023.07.009_bib34","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofaa104","article-title":"What\u2019s hot in clinical infectious diseases? 2019 IDWeek summary","volume":"7","author":"Moss","year":"2020","journal-title":"Open Forum Infect Dis"},{"issue":"2","key":"10.1016\/j.ajt.2023.07.009_bib35","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1111\/ajt.15614","article-title":"Oral fosfomycin for the treatment of lower urinary tract infections among kidney transplant recipients-Results of a Spanish multicenter cohort","volume":"20","author":"L\u00f3pez-Medrano","year":"2020","journal-title":"Am J Transplant"},{"issue":"5","key":"10.1016\/j.ajt.2023.07.009_bib36","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.02267-20","article-title":"Efficacy and safety of oral fosfomycin for asymptomatic bacteriuria in kidney transplant recipients: results from a Spanish multicenter cohort","volume":"95","author":"Ruiz-Ruig\u00f3mez","year":"2023","journal-title":"Antimicrob Agents Chemother"},{"issue":"4","key":"10.1016\/j.ajt.2023.07.009_bib37","first-page":"186","article-title":"Impact of a non-compulsory antibiotic control program (PACTA): cost reductions and decreases in some nosocomial infection","volume":"23","author":"Lopez-Medrano","year":"2005","journal-title":"Enferm Infecc Microbiol Clin"},{"issue":"1","key":"10.1016\/j.ajt.2023.07.009_bib38","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1469-0691.2012.03891.x","article-title":"A\u00a0non-compulsory stewardship programme for the management of antifungals in a university-affiliated hospital","volume":"19","author":"L\u00f3pez-Medrano","year":"2013","journal-title":"Clin Microbiol Infect"},{"issue":"2","key":"10.1016\/j.ajt.2023.07.009_bib39","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.cmi.2017.11.006","article-title":"CMI policy on antimicrobial stewardship research","volume":"24","author":"Pulcini","year":"2018","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.ajt.2023.07.009_bib40","doi-asserted-by":"crossref","first-page":"h4672","DOI":"10.1136\/bmj.h4672","article-title":"Understanding the Hawthorne effect","volume":"351","author":"Sedgwick","year":"2015","journal-title":"BMJ"}],"container-title":["American Journal of Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613523005816?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613523005816?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T05:25:39Z","timestamp":1733030739000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1600613523005816"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":39,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["S1600613523005816"],"URL":"https:\/\/doi.org\/10.1016\/j.ajt.2023.07.009","relation":{},"ISSN":["1600-6135"],"issn-type":[{"value":"1600-6135","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A joint program of antimicrobial stewardship and hospital-acquired infection control to reduce healthcare-associated infections after kidney transplantation: The Hipomenes study","name":"articletitle","label":"Article Title"},{"value":"American Journal of Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajt.2023.07.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}