{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T04:23:19Z","timestamp":1788322999399,"version":"build-2803163510"},"reference-count":25,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U19AI090959"],"award-info":[{"award-number":["U19AI090959"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["amjtransplant.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Transplantation"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.ajt.2023.08.016","type":"journal-article","created":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T05:01:32Z","timestamp":1692939692000},"page":"30-36","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["De novo membranous nephropathy in a pig-to-baboon kidney xenograft: A new xenograft glomerulopathy"],"prefix":"10.1016","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0621-3202","authenticated-orcid":false,"given":"Ivy A.","family":"Rosales","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3267-906X","authenticated-orcid":false,"given":"Kohei","family":"Kinoshita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6216-4890","authenticated-orcid":false,"given":"Akihiro","family":"Maenaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0450-8042","authenticated-orcid":false,"given":"Ira Doressa Anne L.","family":"How","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0148-605X","authenticated-orcid":false,"given":"Martin K.","family":"Selig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9071-9245","authenticated-orcid":false,"given":"Christina M.","family":"Laguerre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5235-8658","authenticated-orcid":false,"given":"A. Bernard","family":"Collins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Ayares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4149-5452","authenticated-orcid":false,"given":"David K.C.","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4493-4150","authenticated-orcid":false,"given":"Robert B.","family":"Colvin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.ajt.2023.08.016_bib1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1111\/ajt.16780","article-title":"Kidney transplantation from triple-knockout pigs expressing multiple human proteins in cynomolgus macaques","volume":"22","author":"Ma","year":"2022","journal-title":"Am J Transplant"},{"issue":"20","key":"10.1016\/j.ajt.2023.08.016_bib2","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1056\/NEJMoa2120238","article-title":"Results of two cases of pig-to-human kidney xenotransplantation","volume":"386","author":"Montgomery","year":"2022","journal-title":"N\u00a0Engl J Med"},{"issue":"4","key":"10.1016\/j.ajt.2023.08.016_bib3","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1111\/ajt.16930","article-title":"First clinical-grade porcine kidney xenotransplant using a human decedent model","volume":"22","author":"Porrett","year":"2022","journal-title":"Am J Transplant"},{"issue":"2","key":"10.1016\/j.ajt.2023.08.016_bib4","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0272-6386(89)80189-1","article-title":"De novo membranous glomerulonephropathy in renal allografts: a report of ten cases and review of the literature","volume":"14","author":"Truong","year":"1989","journal-title":"Am J Kidney Dis"},{"issue":"3","key":"10.1016\/j.ajt.2023.08.016_bib5","first-page":"249","article-title":"Membranous glomerulonephritis (MGN) in transplanted kidneys: morphologic investigation on 256 renal allografts","volume":"6","author":"Monga","year":"1993","journal-title":"Mod Pathol"},{"issue":"2","key":"10.1016\/j.ajt.2023.08.016_bib6","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1399-0012.2010.01213.x","article-title":"De novo membranous nephropathy and antibody-mediated rejection in transplanted kidney","volume":"25","author":"Honda","year":"2011","journal-title":"Clin Transplant"},{"issue":"2","key":"10.1016\/j.ajt.2023.08.016_bib7","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/ki.1982.150","article-title":"De novo membranous nephropathy in human renal allografts: report of nine patients","volume":"22","author":"Cosyns","year":"1982","journal-title":"Kidney Int"},{"issue":"6","key":"10.1016\/j.ajt.2023.08.016_bib8","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1681\/ASN.2021060784","article-title":"Molecular characterization of membranous nephropathy","volume":"33","author":"Sealfon","year":"2022","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"690","key":"10.1016\/j.ajt.2023.08.016_bib9","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.add5318","article-title":"Selective Bcl-2 inhibition promotes hematopoietic chimerism and allograft tolerance without myelosuppression in nonhuman primates","volume":"15","author":"Sasaki","year":"2023","journal-title":"Sci Transl Med"},{"issue":"11","key":"10.1016\/j.ajt.2023.08.016_bib10","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1097\/TP.0000000000002366","article-title":"reference guide to the Banff classification of renal allograft pathology","volume":"102","author":"Roufosse","year":"2018","journal-title":"Transplantation"},{"issue":"8","key":"10.1016\/j.ajt.2023.08.016_bib11","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1111\/j.1600-6143.2006.01351.x","article-title":"Chronic antibody mediated rejection of renal allografts: pathological, serological and immunologic features in nonhuman primates","volume":"6","author":"Smith","year":"2006","journal-title":"Am J Transplant"},{"issue":"6","key":"10.1016\/j.ajt.2023.08.016_bib12","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1016\/j.ekir.2018.07.008","article-title":"Paraffin immunofluorescence: a valuable ancillary technique in renal pathology","volume":"3","author":"Nasr","year":"2018","journal-title":"Kidney Int Rep"},{"issue":"1","key":"10.1016\/j.ajt.2023.08.016_bib13","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1600-0684.1999.tb00085.x","article-title":"Biochemistry and haematology values for the baboon (Papio hamadryas): the effects of sex, growth, development and age","volume":"28","author":"Harewood","year":"1999","journal-title":"J\u00a0Med Primatol"},{"issue":"10","key":"10.1016\/j.ajt.2023.08.016_bib14","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1097\/TP.0000000000002758","article-title":"Membranous nephropathy posttransplantation: an update of the pathophysiology and management","volume":"103","author":"Leon","year":"2019","journal-title":"Transplantation"},{"issue":"4","key":"10.1016\/j.ajt.2023.08.016_bib15","first-page":"321","article-title":"Transplantation-induced immune complex kidney disease in rats with unilateral manifestation in the allografted kidney","volume":"41","author":"Thoenes","year":"1979","journal-title":"Lab Invest"},{"issue":"12","key":"10.1016\/j.ajt.2023.08.016_bib16","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1111\/j.1432-2277.2012.01548.x","article-title":"De novo membranous nephropathy (MN) in kidney allografts. A peculiar form of alloimmune disease?","volume":"25","author":"Ponticelli","year":"2012","journal-title":"Transpl Int"},{"issue":"3","key":"10.1016\/j.ajt.2023.08.016_bib17","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1053\/j.ajkd.2020.01.009","article-title":"Association of HLA typing and alloimmunity with posttransplantation membranous nephropathy: A multicenter case series","volume":"76","author":"Batal","year":"2020","journal-title":"Am J Kidney Dis"},{"issue":"5","key":"10.1016\/j.ajt.2023.08.016_bib18","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1681\/ASN.2021111488","article-title":"Hematopoietic stem cell transplant-membranous nephropathy is associated with protocadherin FAT1","volume":"33","author":"Sethi","year":"2022","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.ajt.2023.08.016_bib19","doi-asserted-by":"crossref","first-page":"800242","DOI":"10.3389\/fimmu.2021.800242","article-title":"How times have changed! A cornucopia of antigens for membranous nephropathy","volume":"12","author":"Caza","year":"2021","journal-title":"Front Immunol"},{"issue":"2","key":"10.1016\/j.ajt.2023.08.016_bib20","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1080\/15227950591008358","article-title":"Posttransplant de novo membranous nephropathy in childhood","volume":"24","author":"Sebire","year":"2005","journal-title":"Fetal Pediatr Pathol"},{"issue":"2","key":"10.1016\/j.ajt.2023.08.016_bib21","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1681\/ASN.2011040429","article-title":"Pathologic\u00a0characteristics of transplanted kidney xenografts","volume":"23","author":"Shimizu","year":"2012","journal-title":"J\u00a0Am Soc\u00a0Nephrol"},{"issue":"4","key":"10.1016\/j.ajt.2023.08.016_bib22","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1681\/ASN.2013040363","article-title":"Rituximab treatment prevents the early development of proteinuria following pig-to-baboon xeno-kidney transplantation","volume":"25","author":"Tasaki","year":"2014","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"6","key":"10.1016\/j.ajt.2023.08.016_bib23","doi-asserted-by":"crossref","DOI":"10.1111\/xen.12708","article-title":"Expression of human CD47 in pig glomeruli prevents proteinuria and prolongs graft survival following pig-to-baboon xenotransplantation","volume":"28","author":"Takeuchi","year":"2021","journal-title":"Xenotransplantation"},{"issue":"10","key":"10.1016\/j.ajt.2023.08.016_bib24","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1111\/tri.13273","article-title":"Upregulation of CD80 on glomerular podocytes plays an important role in development of proteinuria following pig-to-baboon xeno-renal transplantation \u2013 an experimental study","volume":"31","author":"Rivard","year":"2018","journal-title":"Transpl Int"},{"issue":"1","key":"10.1016\/j.ajt.2023.08.016_bib25","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1681\/ASN.2021060794","article-title":"Discovery of autoantibodies targeting nephrin in minimal change disease supports a novel autoimmune etiology","volume":"33","author":"Watts","year":"2022","journal-title":"J\u00a0Am Soc Nephrol"}],"container-title":["American Journal of Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613523006548?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613523006548?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:40:16Z","timestamp":1761630016000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1600613523006548"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["S1600613523006548"],"URL":"https:\/\/doi.org\/10.1016\/j.ajt.2023.08.016","relation":{},"ISSN":["1600-6135"],"issn-type":[{"value":"1600-6135","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"De novo membranous nephropathy in a pig-to-baboon kidney xenograft: A new xenograft glomerulopathy","name":"articletitle","label":"Article Title"},{"value":"American Journal of Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajt.2023.08.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}