{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:57:38Z","timestamp":1780473458242,"version":"3.54.1"},"reference-count":55,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011272","name":"European Commission Seventh Framework Programme for Research and Technological Development Health","doi-asserted-by":"publisher","award":["305499"],"award-info":[{"award-number":["305499"]}],"id":[{"id":"10.13039\/100011272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003130","name":"Fonds Wetenschappelijk Onderzoek Vlaanderen","doi-asserted-by":"publisher","award":["1S93918N"],"award-info":[{"award-number":["1S93918N"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003130","name":"Fonds Wetenschappelijk Onderzoek Vlaanderen","doi-asserted-by":"publisher","award":["1844019N"],"award-info":[{"award-number":["1844019N"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003130","name":"Fonds Wetenschappelijk Onderzoek Vlaanderen","doi-asserted-by":"publisher","award":["G087620N"],"award-info":[{"award-number":["G087620N"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR-22-CE18-0011-01"],"award-info":[{"award-number":["ANR-22-CE18-0011-01"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011102","name":"Seventh Framework Programme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011102","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["amjtransplant.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Transplantation"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.ajt.2024.10.015","type":"journal-article","created":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T20:47:22Z","timestamp":1729802842000},"page":"531-544","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Active immunologic participation and metabolic shutdown of kidney structural cells during kidney transplant rejection"],"prefix":"10.1016","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9796-9157","authenticated-orcid":false,"given":"Elisabet","family":"Van Loon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8417-1661","authenticated-orcid":false,"given":"Baptiste","family":"Lamarth\u00e9e","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2235-9842","authenticated-orcid":false,"given":"Jasper","family":"Callemeyn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imane","family":"Farhat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2313-5122","authenticated-orcid":false,"given":"Priyanka","family":"Koshy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5793-6174","authenticated-orcid":false,"given":"Dany","family":"Anglicheau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9507-0057","authenticated-orcid":false,"given":"Pietro","family":"Cipp\u00e0","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4121-4016","authenticated-orcid":false,"given":"Amelie","family":"Franken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1703-893X","authenticated-orcid":false,"given":"Wilfried","family":"Gwinner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5546-9680","authenticated-orcid":false,"given":"Dirk","family":"Kuypers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7698-0760","authenticated-orcid":false,"given":"Pierre","family":"Marquet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4106-8127","authenticated-orcid":false,"given":"Anna","family":"Rinaldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4595-7570","authenticated-orcid":false,"given":"Claire","family":"Tinel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Van Brussel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4728-9406","authenticated-orcid":false,"given":"Amaryllis","family":"Van Craenenbroeck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3474-7263","authenticated-orcid":false,"given":"Alexis","family":"Varin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1226-3153","authenticated-orcid":false,"given":"Thibaut","family":"Vaulet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3429-302X","authenticated-orcid":false,"given":"Diether","family":"Lambrechts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5625-0792","authenticated-orcid":false,"given":"Maarten","family":"Naesens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.ajt.2024.10.015_bib1","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/j.kint.2018.05.018","article-title":"Analyses of the short- and long-term graft survival after kidney transplantation in Europe between 1986 and 2015","volume":"94","author":"Coemans","year":"2018","journal-title":"Kidney Int"},{"issue":"6","key":"10.1016\/j.ajt.2024.10.015_bib2","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1681\/ASN.2020081215","article-title":"Exploring the complexity of death-censored kidney allograft failure","volume":"32","author":"Mayrdorfer","year":"2021","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"2","key":"10.1016\/j.ajt.2024.10.015_bib3","doi-asserted-by":"crossref","first-page":"e46","DOI":"10.1097\/TP.0000000000003012","article-title":"The causes of kidney allograft failure: more than allo-immunity. A viewpoint article","volume":"104","author":"Van Loon","year":"2020","journal-title":"Transplantation"},{"issue":"4","key":"10.1016\/j.ajt.2024.10.015_bib4","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.kint.2021.11.029","article-title":"Allorecognition and the spectrum of kidney transplant rejection","volume":"101","author":"Callemeyn","year":"2022","journal-title":"Kidney Int"},{"issue":"1","key":"10.1016\/j.ajt.2024.10.015_bib5","doi-asserted-by":"crossref","first-page":"4359","DOI":"10.1038\/s41467-023-39859-7","article-title":"Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII+ innate immune cells in rejection","volume":"14","author":"Lamarth\u00e9e","year":"2023","journal-title":"Nat Commun"},{"issue":"9","key":"10.1016\/j.ajt.2024.10.015_bib6","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1038\/nrneph.2016.85","article-title":"Molecular assessment of disease states in kidney transplant biopsy samples","volume":"12","author":"Halloran","year":"2016","journal-title":"Nat Rev Nephrol"},{"issue":"1","key":"10.1016\/j.ajt.2024.10.015_bib7","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.85323","article-title":"Relationships among injury, fibrosis, and time in human kidney transplants","volume":"1","author":"Venner","year":"2016","journal-title":"JCI Insight"},{"issue":"10","key":"10.1016\/j.ajt.2024.10.015_bib8","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1111\/j.1600-6143.2010.03263.x","article-title":"Loss of solute carriers in T cell-mediated rejection in mouse and human kidneys: an active epithelial injury-repair response","volume":"10","author":"Einecke","year":"2010","journal-title":"Am J Transplant"},{"issue":"8","key":"10.1016\/j.ajt.2024.10.015_bib9","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1111\/j.1600-6143.2009.02727.x","article-title":"Scoring total inflammation is superior to the current Banff inflammation score in predicting outcome and the degree of molecular disturbance in renal allografts","volume":"9","author":"Mengel","year":"2009","journal-title":"Am J Transplant"},{"issue":"3","key":"10.1016\/j.ajt.2024.10.015_bib10","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/j.1600-6143.2008.02546.x","article-title":"The early course of kidney allograft rejection: defining the time when rejection begins","volume":"9","author":"Einecke","year":"2009","journal-title":"Am J Transplant"},{"issue":"2","key":"10.1016\/j.ajt.2024.10.015_bib11","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1038\/ki.1990.46","article-title":"MHC class II, antigen presentation and tumor necrosis factor in renal tubular epithelial cells","volume":"37","author":"Wuthrich","year":"1990","journal-title":"Kidney Int"},{"issue":"3","key":"10.1016\/j.ajt.2024.10.015_bib12","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/ki.1990.221","article-title":"Differing regulation and function of ICAM-1 and class II antigens on renal tubular cells","volume":"38","author":"Jevnikar","year":"1990","journal-title":"Kidney Int"},{"issue":"2","key":"10.1016\/j.ajt.2024.10.015_bib13","first-page":"102","article-title":"The antigen presentation function of renal tubular epithelial cells","volume":"1","author":"Kelley","year":"1993","journal-title":"Exp Nephrol"},{"issue":"2","key":"10.1016\/j.ajt.2024.10.015_bib14","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/s41581-018-0098-z","article-title":"Endothelium structure and function in kidney health and disease","volume":"15","author":"Jourde-Chiche","year":"2019","journal-title":"Nat Rev Nephrol"},{"issue":"9","key":"10.1016\/j.ajt.2024.10.015_bib15","doi-asserted-by":"crossref","first-page":"2318","DOI":"10.1111\/ajt.15898","article-title":"The Banff 2019 Kidney Meeting Report (I): updates on and clarification of criteria for T cell- and antibody-mediated rejection","volume":"20","author":"Loupy","year":"2020","journal-title":"Am J Transplant."},{"issue":"5","key":"10.1016\/j.ajt.2024.10.015_bib16","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1681\/ASN.2020101418","article-title":"Data-driven derivation and validation of novel phenotypes for acute kidney transplant rejection using semi-supervised clustering","volume":"32","author":"Vaulet","year":"2021","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.ajt.2024.10.015_bib17","unstructured":"Algorithm for classification of kidney transplant pathology, with automatic calculation of an \u201cactivity index\u201d and \u201cchronicity index.\u201d RejectionClass. Accessed 19 June 2024. https:\/\/rejectclass.pythonanywhere.com."},{"issue":"6","key":"10.1016\/j.ajt.2024.10.015_bib18","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.133267","article-title":"Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker","volume":"5","author":"Menon","year":"2020","journal-title":"JCI Insight"},{"issue":"9","key":"10.1016\/j.ajt.2024.10.015_bib19","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1681\/ASN.2020030326","article-title":"Harnessing expressed single nucleotide variation and single cell RNA sequencing to define immune cell chimerism in the rejecting kidney transplant","volume":"31","author":"Malone","year":"2020","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"14","key":"10.1016\/j.ajt.2024.10.015_bib20","doi-asserted-by":"crossref","DOI":"10.1172\/JCI170191","article-title":"Single-cell transcriptomic analysis of renal allograft rejection reveals insights into intragraft TCR clonality","volume":"133","author":"Shi","year":"2023","journal-title":"J\u00a0Clin Invest"},{"issue":"W1","key":"10.1016\/j.ajt.2024.10.015_bib21","doi-asserted-by":"crossref","first-page":"W514","DOI":"10.1093\/nar\/gky510","article-title":"OmicsNet: a web-based tool for creation and visual analysis of biological networks in 3D space","volume":"46","author":"Zhou","year":"2018","journal-title":"Nucleic Acids Res"},{"issue":"Database issue","key":"10.1016\/j.ajt.2024.10.015_bib22","doi-asserted-by":"crossref","first-page":"D691","DOI":"10.1093\/nar\/gkq1018","article-title":"Reactome: a database of reactions, pathways and biological processes","volume":"39","author":"Croft","year":"2011","journal-title":"Nucleic Acids Res"},{"issue":"9","key":"10.1016\/j.ajt.2024.10.015_bib23","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1681\/ASN.2020030306","article-title":"Transcriptional changes in kidney allografts with histology of antibody-mediated rejection without anti-HLA donor-specific antibodies","volume":"31","author":"Callemeyn","year":"2020","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"4","key":"10.1016\/j.ajt.2024.10.015_bib24","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1111\/ajt.12150","article-title":"Molecular diagnosis of antibody-mediated rejection in human kidney transplants","volume":"13","author":"Sellar\u00e9s","year":"2013","journal-title":"Am J Transplant"},{"issue":"6","key":"10.1016\/j.ajt.2024.10.015_bib25","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1172\/JCI41789","article-title":"A\u00a0molecular classifier for predicting future graft loss in late kidney transplant biopsies","volume":"120","author":"Einecke","year":"2010","journal-title":"J\u00a0Clin Invest"},{"issue":"1","key":"10.1016\/j.ajt.2024.10.015_bib26","doi-asserted-by":"crossref","first-page":"2832","DOI":"10.1038\/s41467-019-10861-2","article-title":"A\u00a0single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys","volume":"10","author":"Lake","year":"2019","journal-title":"Nat Commun"},{"issue":"6460","key":"10.1016\/j.ajt.2024.10.015_bib27","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1126\/science.aat5031","article-title":"Spatiotemporal immune zonation of the human kidney","volume":"365","author":"Stewart","year":"2019","journal-title":"Science"},{"issue":"9","key":"10.1016\/j.ajt.2024.10.015_bib28","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.1111\/ajt.16059","article-title":"Banff 2019 Meeting Report: molecular diagnostics in solid organ transplantation\u2013Consensus for the Banff Human Organ Transplant (B-HOT) gene panel and open source multicenter validation","volume":"20","author":"Mengel","year":"2020","journal-title":"Am J Transplant"},{"issue":"11","key":"10.1016\/j.ajt.2024.10.015_bib29","doi-asserted-by":"crossref","first-page":"2743","DOI":"10.1681\/ASN.2021040433","article-title":"Donor-specific antibody is associated with increased expression of rejection transcripts in renal transplant biopsies classified as no rejection","volume":"32","author":"Madill-Thomsen","year":"2021","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.ajt.2024.10.015_bib30","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.818569","article-title":"Circulating donor-specific anti-HLA antibodies associate with immune activation independent of kidney transplant histopathological findings","volume":"13","author":"Van Loon","year":"2022","journal-title":"Front Immunol"},{"issue":"5","key":"10.1016\/j.ajt.2024.10.015_bib31","first-page":"F357","article-title":"Stoichiometry and coupling of active transport to oxidative metabolism in epithelial tissues","volume":"240","author":"Mandel","year":"1981","journal-title":"Am J Physiol"},{"issue":"2","key":"10.1016\/j.ajt.2024.10.015_bib32","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/1440-1681.12034","article-title":"Determinants of kidney oxygen consumption and their relationship to tissue oxygen tension in diabetes and hypertension","volume":"40","author":"Hansell","year":"2013","journal-title":"Clin Exp Pharmacol Physiol"},{"issue":"7970","key":"10.1016\/j.ajt.2024.10.015_bib33","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/s41586-023-05769-3","article-title":"An atlas of healthy and injured cell states and niches in the human kidney","volume":"619","author":"Lake","year":"2023","journal-title":"Nature"},{"issue":"27","key":"10.1016\/j.ajt.2024.10.015_bib34","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2026684118","article-title":"Single-nuclear transcriptomics reveals diversity of proximal tubule cell states in\u00a0a dynamic response to acute kidney injury","volume":"118","author":"Gerhardt","year":"2021","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"18","key":"10.1016\/j.ajt.2024.10.015_bib35","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.161783","article-title":"Impaired fatty acid metabolism perpetuates lipotoxicity along the transition to chronic kidney injury","volume":"7","author":"Rinaldi","year":"2022","journal-title":"JCI Insight"},{"issue":"11","key":"10.1016\/j.ajt.2024.10.015_bib36","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1038\/nri3544","article-title":"Immune regulation by atypical chemokine receptors","volume":"13","author":"Nibbs","year":"2013","journal-title":"Nat Rev Immunol"},{"issue":"4","key":"10.1016\/j.ajt.2024.10.015_bib37","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1046\/j.1523-1755.2000.00316.x","article-title":"The Duffy antigen receptor for chemokines is up-regulated during acute renal transplant rejection and crescentic glomerulonephritis","volume":"58","author":"Segerer","year":"2000","journal-title":"Kidney Int"},{"issue":"7","key":"10.1016\/j.ajt.2024.10.015_bib38","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1111\/ajt.14200","article-title":"Comprehensive analysis of transcript changes associated with allograft rejection: combining universal and selective features","volume":"17","author":"Halloran","year":"2017","journal-title":"Am J Transplant"},{"issue":"8","key":"10.1016\/j.ajt.2024.10.015_bib39","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1111\/tri.13904","article-title":"Renal allograft DARCness in subclinical acute and chronic active ABMR","volume":"34","author":"Kl\u00e4ger","year":"2021","journal-title":"Transpl Int"},{"issue":"2","key":"10.1016\/j.ajt.2024.10.015_bib40","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/j.1365-2249.1994.tb06138.x","article-title":"Podocyte expression of MHC class I and II and intercellular adhesion molecule-1 (ICAM-1) in experimental\u00a0pauci-immune crescentic glomerulonephritis","volume":"98","author":"Coers","year":"1994","journal-title":"Clin Exp Immunol"},{"issue":"8","key":"10.1016\/j.ajt.2024.10.015_bib41","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1681\/ASN.2018020125","article-title":"Single-cell transcriptomics of a human kidney allograft biopsy specimen defines a diverse inflammatory response","volume":"29","author":"Wu","year":"2018","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"1","key":"10.1016\/j.ajt.2024.10.015_bib42","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1080\/15548627.2022.2072054","article-title":"Tubular cells produce FGF2 via autophagy after acute kidney injury leading to fibroblast activation and renal fibrosis","volume":"19","author":"Livingston","year":"2023","journal-title":"Autophagy"},{"issue":"3","key":"10.1016\/j.ajt.2024.10.015_bib43","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1038\/ki.2014.75","article-title":"Increased intragraft rejection-associated gene transcripts in patients with donor-specific antibodies and normal biopsies","volume":"86","author":"Hayde","year":"2014","journal-title":"Kidney Int"},{"issue":"3","key":"10.1016\/j.ajt.2024.10.015_bib44","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.cmet.2006.02.002","article-title":"HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia","volume":"3","author":"Kim","year":"2006","journal-title":"Cell Metab."},{"issue":"3","key":"10.1016\/j.ajt.2024.10.015_bib45","doi-asserted-by":"crossref","first-page":"207","DOI":"10.3390\/cells8030207","article-title":"Hypoxia and hypoxia-inducible factors in kidney injury and repair","volume":"8","author":"Shu","year":"2019","journal-title":"Cells"},{"issue":"4","key":"10.1016\/j.ajt.2024.10.015_bib46","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/nrneph.2011.16","article-title":"Pathophysiology of ischemic acute kidney injury","volume":"7","author":"Sharfuddin","year":"2011","journal-title":"Nat Rev Nephrol"},{"issue":"2","key":"10.1016\/j.ajt.2024.10.015_bib47","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1002\/j.2040-4603.2012.tb00431.x","article-title":"Pathophysiology of acute kidney injury","volume":"2","author":"Basile","year":"2012","journal-title":"Compr Physiol"},{"issue":"8","key":"10.1016\/j.ajt.2024.10.015_bib48","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1038\/s42255-020-0238-1","article-title":"Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality","volume":"2","author":"Legouis","year":"2020","journal-title":"Nat Metab"},{"key":"10.1016\/j.ajt.2024.10.015_bib49","article-title":"Transcriptomic responses of the human\u00a0kidney to acute injury at single cell resolution","volume":"2021","author":"Hinze","year":"2021","journal-title":"bioRxiv."},{"issue":"8","key":"10.1016\/j.ajt.2024.10.015_bib50","first-page":"2610","article-title":"Effects of ischemia-reperfusion on tubular cell membrane transporters and consequences in kidney transplantation","volume":"9","author":"Faucher","year":"2020","journal-title":"J\u00a0Clin Med"},{"issue":"6","key":"10.1016\/j.ajt.2024.10.015_bib51","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1369\/jhc.6A7130.2007","article-title":"Alteration in renal organic anion transporter 1 after ischemia\/reperfusion in cadaveric renal allografts","volume":"55","author":"Kwon","year":"2007","journal-title":"J\u00a0Histochem Cytochem"},{"issue":"6","key":"10.1016\/j.ajt.2024.10.015_bib52","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1038\/sj.ki.5002104","article-title":"Downregulation of organic anion transporters in rat kidney under ischemia\/reperfusion-induced acute renal failure","volume":"71","author":"Matsuzaki","year":"2007","journal-title":"Kidney Int."},{"issue":"9249","key":"10.1016\/j.ajt.2024.10.015_bib53","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0140-6736(00)03569-8","article-title":"Endothelial cell chimerism after renal transplantation and vascular rejection","volume":"357","author":"Lagaaij","year":"2001","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.ajt.2024.10.015_bib54","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1097\/01.ASN.0000120369.92378.54","article-title":"Tubular chimerism occurs regularly in renal allografts and is not correlated to outcome","volume":"15","author":"Mengel","year":"2004","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"2","key":"10.1016\/j.ajt.2024.10.015_bib55","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1056\/NEJM200107123450203","article-title":"Neointimal and tubulointerstitial infiltration by recipient mesenchymal cells in chronic renal-allograft rejection","volume":"345","author":"Grimm","year":"2001","journal-title":"N\u00a0Engl J Med"}],"container-title":["American Journal of Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613524006750?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613524006750?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T07:26:00Z","timestamp":1777620360000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1600613524006750"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":55,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S1600613524006750"],"URL":"https:\/\/doi.org\/10.1016\/j.ajt.2024.10.015","relation":{},"ISSN":["1600-6135"],"issn-type":[{"value":"1600-6135","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Active immunologic participation and metabolic shutdown of kidney structural cells during kidney transplant rejection","name":"articletitle","label":"Article Title"},{"value":"American Journal of Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajt.2024.10.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}