{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T23:08:18Z","timestamp":1790377698744,"version":"4.1.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["amjtransplant.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Transplantation"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.ajt.2025.02.007","type":"journal-article","created":{"date-parts":[[2025,2,15]],"date-time":"2025-02-15T16:23:46Z","timestamp":1739636626000},"page":"1568-1574","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Breaking barriers: Successful outcomes of hepatitis C virus D+\/R\u2212 transplants in HIV+ recipients"],"prefix":"10.1016","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4051-5629","authenticated-orcid":false,"given":"Saima","family":"Aslam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8255-9005","authenticated-orcid":false,"given":"Sarah","family":"Hussain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5039-8526","authenticated-orcid":false,"given":"Brandy","family":"Haydel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1635-9136","authenticated-orcid":false,"given":"Sander S.","family":"Florman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5069-1880","authenticated-orcid":false,"given":"Alexander J.","family":"Gilbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9214-9122","authenticated-orcid":false,"given":"Marcus R.","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6466-7347","authenticated-orcid":false,"given":"Nahel","family":"Elias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5752-9576","authenticated-orcid":false,"given":"Jonathan","family":"Hand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8870-1287","authenticated-orcid":false,"given":"Kristin","family":"Mekeel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4392-2200","authenticated-orcid":false,"given":"Gabriel","family":"Schnickel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0003-9899","authenticated-orcid":false,"given":"Mita","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5626-0942","authenticated-orcid":false,"given":"Veeral","family":"Ajmera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0517-3766","authenticated-orcid":false,"given":"Aaron A.R.","family":"Tobian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3465-8647","authenticated-orcid":false,"given":"Jonah","family":"Odim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5288-5125","authenticated-orcid":false,"given":"Allan","family":"Massie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1924-4801","authenticated-orcid":false,"given":"Dorry L.","family":"Segev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2605-9257","authenticated-orcid":false,"given":"Christine M.","family":"Durand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9366-5359","authenticated-orcid":false,"given":"Meenakshi","family":"Rana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ajt.2025.02.007_bib1","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1097\/MOT.0000000000000785","article-title":"New updates in the world of hepatitis C virus infected organ transplantation","volume":"25","author":"Prakash","year":"2020","journal-title":"Curr Opin Organ Transplant"},{"issue":"2","key":"10.1016\/j.ajt.2025.02.007_bib2","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1001\/jamacardio.2019.4748","article-title":"Expanding heart transplant in the era of direct-acting antiviral therapy for hepatitis C","volume":"5","author":"Schlendorf","year":"2020","journal-title":"JAMA Cardiol"},{"issue":"6","key":"10.1016\/j.ajt.2025.02.007_bib3","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1097\/TP.0000000000003382","article-title":"Liver transplantation of HCV-viremic donors into HCV-negative recipients in the USA: increasing frequency with profound geographic variation","volume":"105","author":"Cotter","year":"2021","journal-title":"Transplantation"},{"key":"10.1016\/j.ajt.2025.02.007_bib4","unstructured":"OPTN\/SRTR 2018 Annual Data report: hepatitis C. Accessed August 16, 2024. https:\/\/srtr.transplant.hrsa.gov\/annual_reports\/2018\/Hepatitis%20C.aspx."},{"issue":"11","key":"10.1016\/j.ajt.2025.02.007_bib5","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1016\/j.healun.2019.08.010","article-title":"The impact of using hepatitis C virus nucleic acid test-positive donor hearts on heart transplant waitlist time and transplant rate","volume":"38","author":"Gernhofer","year":"2019","journal-title":"J Heart Lung Transplant"},{"issue":"2","key":"10.1016\/j.ajt.2025.02.007_bib6","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/ajt.16245","article-title":"Cost-effectiveness of using hepatitis C viremic hearts for transplantation into HCV-negative recipients","volume":"21","author":"Logan","year":"2021","journal-title":"Am J Transplant"},{"issue":"7","key":"10.1016\/j.ajt.2025.02.007_bib7","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1016\/j.ekir.2023.04.018","article-title":"Longer-term clinical outcomes from the THINKER and EXPANDER trials of transplantation of HCV-RNA+ donor kidneys into hepatitis C virus-negative recipients","volume":"8","author":"Potluri","year":"2023","journal-title":"Kidney Int Rep"},{"issue":"6","key":"10.1016\/j.ajt.2025.02.007_bib8","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1053\/j.ajkd.2019.11.005","article-title":"Cost-effectiveness of using kidneys from HCV-viremic donors for transplantation into HCV-uninfected recipients","volume":"75","author":"Eckman","year":"2020","journal-title":"Am J Kidney Dis"},{"issue":"11","key":"10.1016\/j.ajt.2025.02.007_bib9","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofac550","article-title":"A pilot trial for prevention of hepatitis C virus transmission from donor to organ transplant recipient with short-course glecaprevir\/pibrentasvir","volume":"9","author":"Ramirez-Sanchez","year":"2022","journal-title":"Open Forum Infect Dis"},{"issue":"11","key":"10.1016\/j.ajt.2025.02.007_bib10","doi-asserted-by":"crossref","first-page":"3734","DOI":"10.1111\/ajt.16747","article-title":"Outcomes of short-duration antiviral prophylaxis for hepatitis C positive donor kidney transplants","volume":"21","author":"Gupta","year":"2021","journal-title":"Am J Transplant"},{"issue":"2","key":"10.1016\/j.ajt.2025.02.007_bib11","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1002\/hep.31060","article-title":"Hepatitis C guidance 2019 update: American Association for the Study of Liver Diseases-Infectious Diseases Society of America recommendations for testing, managing, and treating hepatitis C virus infection","volume":"71","author":"Ghany","year":"2020","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.ajt.2025.02.007_bib12","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1111\/ajt.16886","article-title":"HOPE in action: a prospective multicenter pilot study of liver transplantation from donors with HIV to recipients with HIV","volume":"22","author":"Durand","year":"2022","journal-title":"Am J Transplant"},{"issue":"5","key":"10.1016\/j.ajt.2025.02.007_bib13","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1111\/ajt.16205","article-title":"A prospective multicenter pilot study of HIV-positive deceased donor to HIV-positive recipient kidney transplantation: HOPE in action","volume":"21","author":"Durand","year":"2021","journal-title":"Am J Transplant"},{"issue":"3","key":"10.1016\/j.ajt.2025.02.007_bib14","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1097\/TP.0000000000004857","article-title":"Wait time advantage for transplant candidates with HIV who accept kidneys from donors with HIV under the HOPE act","volume":"108","author":"Motter","year":"2024","journal-title":"Transplantation"},{"issue":"15","key":"10.1016\/j.ajt.2025.02.007_bib15","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1056\/NEJMoa2403733","article-title":"Safety of kidney transplantation from donors with HIV","volume":"391","author":"Durand","year":"2024","journal-title":"N Engl J Med"},{"issue":"11","key":"10.1016\/j.ajt.2025.02.007_bib16","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1093\/cid\/ciab743","article-title":"National landscape of human immunodeficiency virus-positive deceased organ donors in the United States","volume":"74","author":"Werbel","year":"2022","journal-title":"Clin Infect Dis"},{"issue":"10","key":"10.1016\/j.ajt.2025.02.007_bib17","doi-asserted-by":"crossref","first-page":"2579","DOI":"10.1111\/ajt.14993","article-title":"Organs from deceased donors with false-positive HIV screening tests: an unexpected benefit of the HOPE act","volume":"18","author":"Durand","year":"2018","journal-title":"Am J Transplant"},{"issue":"7","key":"10.1016\/j.ajt.2025.02.007_bib18","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1111\/j.1600-6143.2012.04028.x","article-title":"Outcome of HCV\/HIV-coinfected liver transplant recipients: a prospective and multicenter cohort study","volume":"12","author":"Miro","year":"2012","journal-title":"Am J Transplant"},{"issue":"12","key":"10.1016\/j.ajt.2025.02.007_bib19","doi-asserted-by":"crossref","first-page":"2983","DOI":"10.1111\/j.1600-6143.2006.01546.x","article-title":"Survival of liver transplant patients coinfected with HIV and HCV is adversely impacted by recurrent hepatitis C","volume":"6","author":"de Vera","year":"2006","journal-title":"Am J Transplant"},{"issue":"3","key":"10.1016\/j.ajt.2025.02.007_bib20","doi-asserted-by":"crossref","first-page":"467","DOI":"10.2215\/CJN.07460716","article-title":"Access to kidney transplantation among HIV-infected waitlist candidates","volume":"12","author":"Locke","year":"2017","journal-title":"Clin J Am Soc Nephrol"},{"issue":"2","key":"10.1016\/j.ajt.2025.02.007_bib21","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.13466","article-title":"Disparity in access to kidney allograft offers among transplant candidates with human immunodeficiency virus","volume":"33","author":"Cohen","year":"2019","journal-title":"Clin Transplant."},{"issue":"9","key":"10.1016\/j.ajt.2025.02.007_bib22","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1002\/lt.24474","article-title":"Intention-to-treat survival analysis of hepatitis C virus\/human immunodeficiency virus coinfected liver transplant: is it the waiting list?","volume":"22","author":"Araiz","year":"2016","journal-title":"Liver Transpl"},{"issue":"6","key":"10.1016\/j.ajt.2025.02.007_bib23","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1002\/lt.24688","article-title":"Hemophilia liver transplantation observational study","volume":"23","author":"Ragni","year":"2017","journal-title":"Liver Transpl"},{"issue":"10","key":"10.1016\/j.ajt.2025.02.007_bib24","doi-asserted-by":"crossref","first-page":"2496","DOI":"10.1111\/ajt.15054","article-title":"Cost-effectiveness of hepatitis C-positive donor kidney transplantation for hepatitis C-negative recipients with concomitant direct-acting antiviral therapy","volume":"18","author":"Gupta","year":"2018","journal-title":"Am J Transplant"},{"issue":"17","key":"10.1016\/j.ajt.2025.02.007_bib25","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1056\/NEJMoa1812406","article-title":"Heart and lung transplants from HCV-infected donors to uninfected recipients","volume":"380","author":"Woolley","year":"2019","journal-title":"N Engl J Med"},{"issue":"12","key":"10.1016\/j.ajt.2025.02.007_bib26","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/j.healun.2019.08.019","article-title":"Outcomes of heart transplantation from hepatitis C virus-positive donors","volume":"38","author":"Aslam","year":"2019","journal-title":"J Heart Lung Transplant"},{"issue":"4","key":"10.1016\/j.ajt.2025.02.007_bib27","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1053\/j.ajkd.2022.12.019","article-title":"Kidney Transplantation from hepatitis C virus-infected donors to uninfected recipients: a systematic review for the KDIGO 2022 hepatitis C clinical practice guideline update","volume":"82","author":"Gordon","year":"2023","journal-title":"Am J Kidney Dis"}],"container-title":["American Journal of Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613525000905?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613525000905?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:39:18Z","timestamp":1782952758000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1600613525000905"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":27,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["S1600613525000905"],"URL":"https:\/\/doi.org\/10.1016\/j.ajt.2025.02.007","relation":{},"ISSN":["1600-6135"],"issn-type":[{"value":"1600-6135","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Breaking barriers: Successful outcomes of hepatitis C virus D+\/R\u2212 transplants in HIV+ recipients","name":"articletitle","label":"Article Title"},{"value":"American Journal of Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajt.2025.02.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Inc. on behalf of American Society of Transplantation & American Society of Transplant Surgeons.","name":"copyright","label":"Copyright"}]}}