{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:48:55Z","timestamp":1782953335901,"version":"3.54.5"},"reference-count":24,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["amjtransplant.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Transplantation"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.ajt.2025.02.009","type":"journal-article","created":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T11:58:49Z","timestamp":1739879929000},"page":"1540-1546","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Perioperative C1-esterase inhibitor therapy to allow transplantation in a highly sensitized lung transplant candidate: Three case reports"],"prefix":"10.1016","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3207-9177","authenticated-orcid":false,"given":"J\u00e9r\u00f4me","family":"Devaquet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8896-5346","authenticated-orcid":false,"given":"Benjamin","family":"Coiffard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0045-2018","authenticated-orcid":false,"given":"Xavier","family":"Demant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1868-6728","authenticated-orcid":false,"given":"Fran\u00e7ois","family":"Parquin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1198-4677","authenticated-orcid":false,"given":"Magali","family":"Devriese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7654-474X","authenticated-orcid":false,"given":"Edouard","family":"Sage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9299-3705","authenticated-orcid":false,"given":"Pascal","family":"Pedini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2243-0736","authenticated-orcid":false,"given":"Cl\u00e9ment","family":"Picard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6703-5481","authenticated-orcid":false,"given":"Florence","family":"Daviet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6747-4583","authenticated-orcid":false,"given":"Xavier Benoit","family":"D\u2019Journo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9671-1263","authenticated-orcid":false,"given":"Gwendaline","family":"Guidicelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2237-4172","authenticated-orcid":false,"given":"Natalia","family":"Belousova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2387-0669","authenticated-orcid":false,"given":"Antoine","family":"Roux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajt.2025.02.009_bib1","doi-asserted-by":"crossref","first-page":"383","DOI":"10.12659\/AOT.915769","article-title":"Effect of calculated panel reactive antibody value on waitlist outcomes for lung transplant candidates","volume":"24","author":"Aversa","year":"2019","journal-title":"Ann Transplant"},{"issue":"6","key":"10.1016\/j.ajt.2025.02.009_bib2","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1016\/j.athoracsur.2008.02.011","article-title":"Pretransplant panel reactive antibodies in human lung transplantation: an analysis of over 10,000 patients","volume":"85","author":"Shah","year":"2008","journal-title":"Ann Thorac Surg"},{"issue":"2","key":"10.1016\/j.ajt.2025.02.009_bib3","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1378\/chest.110.2.559","article-title":"Hyperacute rejection following lung transplantation","volume":"110","author":"Frost","year":"1996","journal-title":"Chest"},{"issue":"6","key":"10.1016\/j.ajt.2025.02.009_bib4","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.healun.2007.03.007","article-title":"Hyperacute rejection after lung transplantation caused by undetected low-titer anti-HLA antibodies","volume":"26","author":"Masson","year":"2007","journal-title":"J Heart Lung Transplant"},{"issue":"5","key":"10.1016\/j.ajt.2025.02.009_bib5","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1097\/TP.0b013e31827afb0f","article-title":"Lung transplantation in patients with pretransplantation donor-specific antibodies detected by Luminex assay","volume":"95","author":"Brugi\u00e8re","year":"2013","journal-title":"Transplantation"},{"issue":"4","key":"10.1016\/j.ajt.2025.02.009_bib6","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.healun.2010.01.012","article-title":"Antibody-mediated rejection in lung transplantation: myth or reality?","volume":"29","author":"Glanville","year":"2010","journal-title":"J Heart Lung Transplant"},{"issue":"10","key":"10.1016\/j.ajt.2025.02.009_bib7","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1016\/j.healun.2014.02.033","article-title":"Pre-transplant donor HLA-specific antibodies: characteristics causing detrimental effects on survival after lung transplantation","volume":"33","author":"Smith","year":"2014","journal-title":"J Heart Lung Transplant"},{"issue":"10","key":"10.1016\/j.ajt.2025.02.009_bib8","doi-asserted-by":"crossref","first-page":"3444","DOI":"10.1111\/ajt.16707","article-title":"Long-term outcomes of sensitized lung transplant recipients after peri-operative desensitization","volume":"21","author":"Aversa","year":"2021","journal-title":"Am J Transplant"},{"issue":"4","key":"10.1016\/j.ajt.2025.02.009_bib9","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1111\/ajt.12636","article-title":"Antibody desensitization therapy in highly sensitized lung transplant candidates","volume":"14","author":"Snyder","year":"2014","journal-title":"Am J Transplant"},{"issue":"5","key":"10.1016\/j.ajt.2025.02.009_bib10","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.04090-2020","article-title":"A virtual crossmatch-based strategy for perioperative desensitisation in lung transplant recipients with pre-formed donor-specific antibodies: 3-year outcome","volume":"58","author":"Parquin","year":"2021","journal-title":"Eur Respir J"},{"issue":"2","key":"10.1016\/j.ajt.2025.02.009_bib11","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/ajt.13076","article-title":"Survival in sensitized lung transplant recipients with perioperative desensitization","volume":"15","author":"Tinckam","year":"2015","journal-title":"Am J Transplant"},{"issue":"11","key":"10.1016\/j.ajt.2025.02.009_bib12","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1111\/j.1600-6143.2011.03757.x","article-title":"Terminal complement inhibition decreases antibody-mediated rejection in sensitized renal transplant recipients","volume":"11","author":"Stegall","year":"2011","journal-title":"Am J Transplant"},{"issue":"12","key":"10.1016\/j.ajt.2025.02.009_bib13","doi-asserted-by":"crossref","first-page":"3468","DOI":"10.1111\/ajt.13871","article-title":"Plasma-derived C1 esterase inhibitor for acute antibody-mediated rejection following kidney transplantation: results of a randomized double-blind placebo-controlled pilot study","volume":"16","author":"Montgomery","year":"2016","journal-title":"Am J Transplant"},{"issue":"7","key":"10.1016\/j.ajt.2025.02.009_bib14","doi-asserted-by":"crossref","first-page":"2479","DOI":"10.1111\/ajt.16420","article-title":"Complement inhibition for prevention of antibody-mediated rejection in immunologically high-risk heart allograft recipients","volume":"21","author":"Patel","year":"2021","journal-title":"Am J Transplant"},{"issue":"4","key":"10.1016\/j.ajt.2025.02.009_bib15","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.02027-2019","article-title":"C1-esterase inhibitor treatment for antibody-mediated rejection after lung transplantation: two case reports","volume":"55","author":"Parquin","year":"2020","journal-title":"Eur Respir J"},{"key":"10.1016\/j.ajt.2025.02.009_bib16","unstructured":"Eurotransplant Reference Laboratory. Virtual PRA calculator. Accessed November 20, 2024. https:\/\/www.etrl.org\/vPRA.aspx."},{"issue":"3","key":"10.1016\/j.ajt.2025.02.009_bib17","doi-asserted-by":"crossref","first-page":"e205","DOI":"10.1016\/j.athoracsur.2016.01.081","article-title":"Logistic ex vivo lung perfusion for hyperimmunized patients","volume":"102","author":"De Wolf","year":"2016","journal-title":"Ann Thorac Surg"},{"issue":"4","key":"10.1016\/j.ajt.2025.02.009_bib18","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.humimm.2005.01.025","article-title":"Utility of peritransplant and rescue intravenous immunoglobulin and extracorporeal immunoadsorption in lung transplant recipients sensitized to HLA antigens","volume":"66","author":"Appel","year":"2005","journal-title":"Hum Immunol"},{"issue":"9","key":"10.1016\/j.ajt.2025.02.009_bib19","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1097\/TP.0000000000002717","article-title":"Update on C1 esterase inhibitor in human solid organ transplantation","volume":"103","author":"Berger","year":"2019","journal-title":"Transplantation"},{"issue":"3","key":"10.1016\/j.ajt.2025.02.009_bib20","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.trim.2015.04.004","article-title":"Interference of therapeutic antibodies used in desensitization protocols on lymphocytotoxicity crossmatch results","volume":"32","author":"Milongo","year":"2015","journal-title":"Transpl Immunol"},{"issue":"11","key":"10.1016\/j.ajt.2025.02.009_bib21","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1097\/TP.0000000000000034","article-title":"C1-esterase-inhibitor for primary graft dysfunction in lung transplantation","volume":"97","author":"Sommer","year":"2014","journal-title":"Transplantation"},{"issue":"4","key":"10.1016\/j.ajt.2025.02.009_bib22","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.healun.2016.01.1223","article-title":"Antibody-mediated rejection of the lung: a consensus report of the International Society for Heart and Lung Transplantation","volume":"35","author":"Levine","year":"2016","journal-title":"J Heart Lung Transplant"},{"issue":"1","key":"10.1016\/j.ajt.2025.02.009_bib23","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/ajt.14990","article-title":"Banff Lung Report: current knowledge and future research perspectives for diagnosis and treatment of pulmonary antibody-mediated rejection (AMR)","volume":"19","author":"Roux","year":"2019","journal-title":"Am J Transplant"},{"issue":"5","key":"10.1016\/j.ajt.2025.02.009_bib24","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1111\/ajt.13663","article-title":"C1 inhibitor in acute antibody-mediated rejection nonresponsive to conventional therapy in kidney transplant recipients: a pilot study","volume":"16","author":"Viglietti","year":"2016","journal-title":"Am J Transplant"}],"container-title":["American Journal of Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613525000929?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613525000929?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:39:36Z","timestamp":1782952776000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1600613525000929"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":24,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["S1600613525000929"],"URL":"https:\/\/doi.org\/10.1016\/j.ajt.2025.02.009","relation":{},"ISSN":["1600-6135"],"issn-type":[{"value":"1600-6135","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Perioperative C1-esterase inhibitor therapy to allow transplantation in a highly sensitized lung transplant candidate: Three case reports","name":"articletitle","label":"Article Title"},{"value":"American Journal of Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajt.2025.02.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}