{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T15:39:18Z","timestamp":1792597158183,"version":"4.5.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI22\/01019"],"award-info":[{"award-number":["PI22\/01019"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI23\/01909"],"award-info":[{"award-number":["PI23\/01909"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI22\/00749"],"award-info":[{"award-number":["PI22\/00749"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["RICORS2040-Renal"],"award-info":[{"award-number":["RICORS2040-Renal"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["amjtransplant.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Transplantation"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.ajt.2026.04.027","type":"journal-article","created":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T22:57:24Z","timestamp":1777762644000},"page":"2327-2335","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Normothermic regional perfusion in kidney transplants with donors after controlled circulatory death: Functional benefits and safety in older recipients"],"prefix":"10.1016","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5983-6863","authenticated-orcid":false,"given":"N\u00e9stor","family":"Toapanta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0890-3012","authenticated-orcid":false,"given":"Jordi","family":"Comas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6199-3016","authenticated-orcid":false,"given":"Fritz","family":"Diekmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6965-3745","authenticated-orcid":false,"given":"Edoardo","family":"Melilli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8601-2699","authenticated-orcid":false,"given":"Mar\u00eda Jos\u00e9","family":"P\u00e9rez-Saez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3088-0590","authenticated-orcid":false,"given":"Anna","family":"Vila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1254-5553","authenticated-orcid":false,"given":"Carme","family":"Facundo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3371-1840","authenticated-orcid":false,"given":"Emma","family":"Arcos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4615-2985","authenticated-orcid":false,"given":"Jaume","family":"Tort","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8838-3007","authenticated-orcid":false,"given":"Alberto","family":"Sandiumenge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7267-3963","authenticated-orcid":false,"given":"Francesc","family":"Moreso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9468-7920","authenticated-orcid":false,"given":"Oriol","family":"Bestard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.ajt.2026.04.027_bib1","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1111\/j.1600-6143.2011.03686.x","article-title":"Systematic review: Kidney transplantation compared with dialysis in clinically relevant outcomes","volume":"11","author":"Tonelli","year":"2011","journal-title":"Am J Transplant"},{"issue":"5","key":"10.1016\/j.ajt.2026.04.027_bib2","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1093\/ndt\/gfp681","article-title":"Benefit of kidney transplantation beyond 70 years of age","volume":"25","author":"Heldal","year":"2010","journal-title":"Nephrol Dial Transplant"},{"issue":"12","key":"10.1016\/j.ajt.2026.04.027_bib3","doi-asserted-by":"crossref","first-page":"2507","DOI":"10.1111\/tri.14141","article-title":"Kidney transplant outcomes in elderly recipients with controlled donation after circulatory death or donation after brain death donors: a registry cohort study","volume":"34","author":"P\u00e9rez-S\u00e1ez","year":"2021","journal-title":"Transpl Int"},{"issue":"12","key":"10.1016\/j.ajt.2026.04.027_bib4","doi-asserted-by":"crossref","first-page":"2494","DOI":"10.1111\/tri.14131","article-title":"Deciphering transplant outcomes of expanded kidney allografts donated after controlled circulatory death in the current transplant era. A call for caution","volume":"34","author":"Montero","year":"2021","journal-title":"Transpl Int"},{"issue":"5","key":"10.1016\/j.ajt.2026.04.027_bib5","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1093\/ndt\/gfab304","article-title":"Evaluation of severity of delayed graft function in kidney transplant recipients","volume":"37","author":"Schrezenmeier","year":"2022","journal-title":"Nephrol Dial Transplant"},{"issue":"11","key":"10.1016\/j.ajt.2026.04.027_bib6","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1111\/j.1600-6143.2011.03754.x","article-title":"Delayed graft function in the kidney transplant","volume":"11","author":"Siedlecki","year":"2011","journal-title":"Am J Transplant"},{"issue":"6","key":"10.1016\/j.ajt.2026.04.027_bib7","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1097\/TP.0000000000001323","article-title":"Association between delayed graft function & graft loss in donation after cardiac death kidney transplants-a paired kidney registry analysis","volume":"101","author":"Lim","year":"2017","journal-title":"Transplantation"},{"issue":"3","key":"10.1016\/j.ajt.2026.04.027_bib8","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.kint.2015.09.002","article-title":"Prolonged warm ischemia time is associated with graft failure and mortality after kidney transplantation","volume":"89","author":"Tennankore","year":"2016","journal-title":"Kidney Int"},{"issue":"10","key":"10.1016\/j.ajt.2026.04.027_bib9","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.40130","article-title":"Normothermic regional perfusion experience of organ procurement organizations in the US","volume":"7","author":"Sellers","year":"2024","journal-title":"JAMA Netw Open"},{"issue":"12","key":"10.1016\/j.ajt.2026.04.027_bib10","doi-asserted-by":"crossref","first-page":"2846","DOI":"10.1111\/ajt.12927","article-title":"In situ normothermic regional perfusion for controlled donation after circulatory death - the United Kingdom experience","volume":"14","author":"Oniscu","year":"2014","journal-title":"Am J Transplant"},{"issue":"8","key":"10.1016\/j.ajt.2026.04.027_bib11","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1111\/ajt.14214","article-title":"Improving the outcomes of organs obtained from controlled donation after circulatory death donors using abdominal normothermic regional perfusion","volume":"17","author":"Mi\u00f1ambres","year":"2017","journal-title":"Am J Transplant"},{"issue":"11","key":"10.1016\/j.ajt.2026.04.027_bib12","doi-asserted-by":"crossref","first-page":"3618","DOI":"10.1111\/ajt.16622","article-title":"Improved short-term outcomes of kidney transplants in controlled donation after the circulatory determination of death with the use of normothermic regional perfusion","volume":"21","author":"Padilla","year":"2021","journal-title":"Am J Transplant"},{"issue":"1","key":"10.1016\/j.ajt.2026.04.027_bib13","doi-asserted-by":"crossref","first-page":"60","DOI":"10.23736\/S2724-6051.23.05393-4","article-title":"Graft survival and delayed graft function with normothermic regional perfusion and rapid recovery after circulatory death in kidney transplantation: a propensity score matching study","volume":"76","author":"Salguero","year":"2024","journal-title":"Minerva Urol Nephrol"},{"issue":"5","key":"10.1016\/j.ajt.2026.04.027_bib14","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1097\/SLA.0000000000003515","article-title":"The neglectable impact of delayed graft function on long-term graft survival in kidneys donated after circulatory death associates with superior organ resilience","volume":"270","author":"De Kok","year":"2019","journal-title":"Ann Surg"},{"issue":"2","key":"10.1016\/j.ajt.2026.04.027_bib15","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1111\/j.1600-6143.2012.04323.x","article-title":"Quantification of the early risk of death in elderly kidney transplant recipients","volume":"13","author":"Gill","year":"2013","journal-title":"Am J Transplant"},{"issue":"1","key":"10.1016\/j.ajt.2026.04.027_bib16","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/ajt.12992","article-title":"Frailty and mortality in kidney transplant recipients","volume":"15","author":"McAdams-Demarco","year":"2015","journal-title":"Am J Transplant"},{"key":"10.1016\/j.ajt.2026.04.027_bib17","doi-asserted-by":"crossref","DOI":"10.3389\/ti.2024.13452","article-title":"Benefits of living over deceased donor kidney transplantation in elderly recipients. A propensity score matched analysis of a large European registry cohort","volume":"37","author":"Toapanta","year":"2024","journal-title":"Transpl Int"},{"issue":"1","key":"10.1016\/j.ajt.2026.04.027_bib18","doi-asserted-by":"crossref","DOI":"10.1136\/bmjoq-2022-002149","article-title":"Reducing length of stay in patients following liver transplantation using the model for continuous improvement","volume":"12","author":"Sachar","year":"2023","journal-title":"BMJ Open Qual"},{"issue":"5","key":"10.1016\/j.ajt.2026.04.027_bib19","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1111\/ajt.12179","article-title":"Renal transplantation after ex vivo normothermic perfusion: the first clinical study","volume":"13","author":"Hosgood","year":"2013","journal-title":"Am J Transplant"},{"issue":"4","key":"10.1016\/j.ajt.2026.04.027_bib20","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1002\/bjs.10733","article-title":"Normothermic machine perfusion for the assessment and transplantation of declined human kidneys from donation after circulatory death donors","volume":"105","author":"Hosgood","year":"2018","journal-title":"Br J Surg"},{"issue":"9","key":"10.1016\/j.ajt.2026.04.027_bib21","article-title":"Postoperative length of stay following kidney transplantation in patients without delayed graft function\u2014an analysis of center-level variation and patient outcomes","volume":"37","author":"Bakhtiyar","year":"2023","journal-title":"Clin Transplant"},{"issue":"8","key":"10.1016\/j.ajt.2026.04.027_bib22","doi-asserted-by":"crossref","first-page":"3286","DOI":"10.21037\/tau-21-236","article-title":"Comparison of in situ preservation techniques for kidneys from donors after circulatory death: a systematic review and meta-analysis","volume":"10","author":"Medina","year":"2021","journal-title":"Transl Androl Urol"}],"container-title":["American Journal of Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613526002352?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613526002352?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T14:42:04Z","timestamp":1792593724000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1600613526002352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":22,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["S1600613526002352"],"URL":"https:\/\/doi.org\/10.1016\/j.ajt.2026.04.027","relation":{},"ISSN":["1600-6135"],"issn-type":[{"value":"1600-6135","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Normothermic regional perfusion in kidney transplants with donors after controlled circulatory death: Functional benefits and safety in older recipients","name":"articletitle","label":"Article Title"},{"value":"American Journal of Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajt.2026.04.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}