{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T17:16:10Z","timestamp":1793121370229,"version":"4.5.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100006492","name":"National Institute of Allergy and Infectious Diseases Division of Intramural Research","doi-asserted-by":"publisher","award":["K23AI175676"],"award-info":[{"award-number":["K23AI175676"]}],"id":[{"id":"10.13039\/100006492","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["amjtransplant.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Transplantation"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.ajt.2026.04.029","type":"journal-article","created":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T23:28:34Z","timestamp":1778023714000},"page":"2182-2193","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["De novo belatacept-based immunosuppression is not associated with increased risk of invasive fungal infection in kidney transplant recipients"],"prefix":"10.1016","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2469-0638","authenticated-orcid":false,"given":"Emily M.","family":"Eichenberger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0267-9665","authenticated-orcid":false,"given":"Geeta M.","family":"Karadkhele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5287-4792","authenticated-orcid":false,"given":"Payas","family":"Vasanth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6573-2649","authenticated-orcid":false,"given":"Christian","family":"Larsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ajt.2026.04.029_bib1","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1056\/NEJMoa1506027","article-title":"Belatacept and long-term outcomes in kidney transplantation","volume":"374","author":"Vincenti","year":"2016","journal-title":"N Engl J Med"},{"issue":"2","key":"10.1016\/j.ajt.2026.04.029_bib2","doi-asserted-by":"crossref","first-page":"e302","DOI":"10.1097\/TP.0000000000005506","article-title":"Tailoring of immunosuppression with belatacept in de novo and conversion settings and risk mitigation strategies","volume":"110","author":"Formica","year":"2026","journal-title":"Transplantation"},{"issue":"11","key":"10.1016\/j.ajt.2026.04.029_bib3","doi-asserted-by":"crossref","first-page":"2875","DOI":"10.1111\/ajt.12460","article-title":"Long-term belatacept exposure maintains efficacy and safety at 5 years: results from the long-term extension of the BENEFIT study","volume":"13","author":"Rostaing","year":"2013","journal-title":"Am J Transplant"},{"issue":"11","key":"10.1016\/j.ajt.2026.04.029_bib4","doi-asserted-by":"crossref","first-page":"2922","DOI":"10.1111\/ajt.14353","article-title":"Belatacept combined with transient calcineurin inhibitor therapy prevents rejection and promotes improved long-term renal allograft function","volume":"17","author":"Adams","year":"2017","journal-title":"Am J Transplant"},{"issue":"2","key":"10.1016\/j.ajt.2026.04.029_bib5","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.ajt.2023.09.011","article-title":"Belatacept with time-limited tacrolimus coimmunosuppression modifies the 3-year risk of eplet mismatch in kidney transplantation","volume":"24","author":"Johnson","year":"2024","journal-title":"Am J Transplant"},{"issue":"5","key":"10.1016\/j.ajt.2026.04.029_bib6","doi-asserted-by":"crossref","DOI":"10.1111\/tid.14298","article-title":"Belatacept-based immunosuppression does not confer increased risk of BK polyomavirus-DNAemia relative to tacrolimus-based immunosuppression","volume":"26","author":"Eichenberger","year":"2024","journal-title":"Transpl Infect Dis"},{"issue":"6","key":"10.1016\/j.ajt.2026.04.029_bib7","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1093\/cid\/ciz1008","article-title":"Revision and update of the consensus definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium","volume":"71","author":"Donnelly","year":"2020","journal-title":"Clin Infect Dis"},{"issue":"11","key":"10.1016\/j.ajt.2026.04.029_bib8","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1097\/TP.0000000000002366","article-title":"A 2018 Reference Guide to the Banff classification of renal allograft pathology","volume":"102","author":"Roufosse","year":"2018","journal-title":"Transplantation"},{"issue":"9398","key":"10.1016\/j.ajt.2026.04.029_bib9","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1016\/S0140-6736(03)14904-5","article-title":"Glucocorticoids and invasive fungal infections","volume":"362","author":"Lionakis","year":"2003","journal-title":"Lancet Lond Engl"},{"issue":"1","key":"10.1016\/j.ajt.2026.04.029_bib10","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1111\/ajt.16132","article-title":"CMV high-risk status and posttransplant outcomes in kidney transplant recipients treated with belatacept","volume":"21","author":"Karadkhele","year":"2021","journal-title":"Am J Transplant"},{"key":"10.1016\/j.ajt.2026.04.029_bib11","author":"Ho"},{"key":"10.1016\/j.ajt.2026.04.029_bib12","author":"Bowers"},{"key":"10.1016\/j.ajt.2026.04.029_bib13","series-title":"cobalt: Covariate Balance Tables and Plots","author":"Greifer","year":"2025"},{"key":"10.1016\/j.ajt.2026.04.029_bib14","series-title":"until 2009) TL (original S >R port and R maintainer, Elizabeth A, Cynthia C. survival: Survival Analysis","author":"Therneau","year":"2024"},{"key":"10.1016\/j.ajt.2026.04.029_bib15","author":"Wickham"},{"key":"10.1016\/j.ajt.2026.04.029_bib16","author":"Sjoberg"},{"key":"10.1016\/j.ajt.2026.04.029_bib17","author":"Sjoberg"},{"issue":"8","key":"10.1016\/j.ajt.2026.04.029_bib18","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1086\/651262","article-title":"Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET)","volume":"50","author":"Pappas","year":"2010","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1016\/j.ajt.2026.04.029_bib19","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.amjms.2019.10.008","article-title":"Risk factors associated with invasive fungal infections in kidney transplant patients","volume":"359","author":"Leitheiser","year":"2020","journal-title":"Am J Med Sci"},{"issue":"2","key":"10.1016\/j.ajt.2026.04.029_bib20","doi-asserted-by":"crossref","DOI":"10.1111\/tid.13250","article-title":"Incidence and outcomes of invasive fungal infection among solid organ transplant recipients: a population-based cohort study","volume":"22","author":"Hosseini-Moghaddam","year":"2020","journal-title":"Transpl Infect Dis"},{"issue":"1-2","key":"10.1016\/j.ajt.2026.04.029_bib21","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s11046-015-9875-4","article-title":"Invasive fungal infections in renal transplant recipients: Epidemiology and risk factors","volume":"180","author":"Sahin","year":"2015","journal-title":"Mycopathologia"},{"issue":"7","key":"10.1016\/j.ajt.2026.04.029_bib22","doi-asserted-by":"crossref","first-page":"2306","DOI":"10.1016\/j.transproceed.2016.06.019","article-title":"Invasive fungal disease in renal transplant recipients at a Brazilian center: local epidemiology matters","volume":"48","author":"Guimar\u00e3es","year":"2016","journal-title":"Transplant Proc"},{"issue":"6","key":"10.1016\/j.ajt.2026.04.029_bib23","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofae158","article-title":"An unexpectedly high incidence of invasive fungal diseases in solid organ transplant recipients taking belatacept for organ rejection prophylaxis: a single-center retrospective cohort study","volume":"11","author":"Bell","year":"2024","journal-title":"Open Forum Infect Dis"},{"issue":"11","key":"10.1016\/j.ajt.2026.04.029_bib24","doi-asserted-by":"crossref","first-page":"6695","DOI":"10.21037\/jtd-2021-26","article-title":"Fungal infections in lung transplantation","volume":"13","author":"Samanta","year":"2021","journal-title":"J Thorac Dis"},{"issue":"9","key":"10.1016\/j.ajt.2026.04.029_bib25","doi-asserted-by":"crossref","first-page":"2924","DOI":"10.1016\/j.transproceed.2016.05.017","article-title":"Risk evaluation and outcome of pneumocystis jirovecii pneumonia in kidney transplant patients","volume":"48","author":"Brakemeier","year":"2016","journal-title":"Transplant Proc"},{"issue":"2","key":"10.1016\/j.ajt.2026.04.029_bib26","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1093\/ndt\/gfz255","article-title":"Opportunistic infections after conversion to belatacept in kidney transplantation","volume":"35","author":"Bertrand","year":"2020","journal-title":"Nephrol Dial Transplant"},{"issue":"11","key":"10.1016\/j.ajt.2026.04.029_bib27","doi-asserted-by":"crossref","first-page":"3479","DOI":"10.3390\/jcm9113479","article-title":"Opportunistic infections and efficacy following conversion to belatacept-based therapy after kidney transplantation: A French multicenter cohort","volume":"9","author":"Bertrand","year":"2020","journal-title":"J Clin Med"},{"issue":"3","key":"10.1016\/j.ajt.2026.04.029_bib28","article-title":"Risk of opportunistic infection in kidney transplant recipients with cytomegalovirus infection and associated outcomes","volume":"21","author":"Jorgenson","year":"2019","journal-title":"Transpl Infect"},{"issue":"6","key":"10.1016\/j.ajt.2026.04.029_bib29","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1097\/QCO.0000000000000502","article-title":"Invasive fungal disease and cytomegalovirus infection: is there an association?","volume":"31","author":"Yong","year":"2018","journal-title":"Curr Opin Infect Dis"},{"issue":"9","key":"10.1016\/j.ajt.2026.04.029_bib30","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.1111\/ajt.15371","article-title":"Improving our mechanistic understanding of the indirect effects of CMV infection in transplant recipients","volume":"19","author":"L\u2019Huillier","year":"2019","journal-title":"Am J Transplant"},{"issue":"4","key":"10.1016\/j.ajt.2026.04.029_bib31","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1093\/cid\/ciw326","article-title":"Practice guidelines for the diagnosis and management of aspergillosis: 2016 update by the Infectious Diseases Society of America","volume":"63","author":"Patterson","year":"2016","journal-title":"Clin Infect Dis"},{"issue":"4","key":"10.1016\/j.ajt.2026.04.029_bib32","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1086\/322685","article-title":"Fungal infections in older adults","volume":"33","author":"Kauffman","year":"2001","journal-title":"Clin Infect Dis"},{"issue":"1","key":"10.1016\/j.ajt.2026.04.029_bib33","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s10096-009-0822-5","article-title":"Mycoses in the elderly","volume":"29","author":"Hof","year":"2010","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"6","key":"10.1016\/j.ajt.2026.04.029_bib34","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.3390\/jcm9061824","article-title":"Invasive fungal diseases in kidney transplant recipients: risk factors for mortality","volume":"9","author":"Seok","year":"2020","journal-title":"J Clin Med"},{"issue":"9","key":"10.1016\/j.ajt.2026.04.029_bib35","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.13553","article-title":"AST Infectious Diseases Community of Practice. Endemic fungal infections in solid organ transplant recipients-guidelines from the American Society of Transplantation Infectious Diseases Community of Practice","volume":"33","author":"Miller","year":"2019","journal-title":"Clin Transplant"},{"issue":"9","key":"10.1016\/j.ajt.2026.04.029_bib36","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.13544","article-title":"Invasive Aspergillosis in solid-organ transplant recipients: guidelines from the American Society of Transplantation Infectious Diseases Community of Practice","volume":"33","author":"Husain","year":"2019","journal-title":"Clin Transplant"},{"issue":"9","key":"10.1016\/j.ajt.2026.04.029_bib37","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.13525","article-title":"Practice the AIDC of. Emerging fungal infections in solid organ transplant recipients: Guidelines of the American Society of Transplantation Infectious Diseases Community of Practice","volume":"33","author":"Shoham","year":"2019","journal-title":"Clin Transplant"},{"issue":"9","key":"10.1016\/j.ajt.2026.04.029_bib38","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.13543","article-title":"Cryptococcosis in solid organ transplantation-Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice","volume":"33","author":"Baddley","year":"2019","journal-title":"Clin Transplant"}],"container-title":["American Journal of Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613526002376?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613526002376?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T21:04:02Z","timestamp":1787778242000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1600613526002376"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":38,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S1600613526002376"],"URL":"https:\/\/doi.org\/10.1016\/j.ajt.2026.04.029","relation":{},"ISSN":["1600-6135"],"issn-type":[{"value":"1600-6135","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"De novo belatacept-based immunosuppression is not associated with increased risk of invasive fungal infection in kidney transplant recipients","name":"articletitle","label":"Article Title"},{"value":"American Journal of Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajt.2026.04.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}