{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T14:08:22Z","timestamp":1779890902740,"version":"3.53.1"},"reference-count":87,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Alcohol"],"published-print":{"date-parts":[[2007,11]]},"DOI":"10.1016\/j.alcohol.2007.07.009","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T15:22:09Z","timestamp":1196090529000},"page":"469-478","source":"Crossref","is-referenced-by-count":50,"title":["Pueraria lobata (Kudzu root) hangover remedies and acetaldehyde-associated neoplasm risk"],"prefix":"10.1016","volume":"41","author":[{"given":"Neil R.","family":"McGregor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.alcohol.2007.07.009_bib1","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/S0369-8114(01)00242-5","article-title":"Genetic polymorphisms of alcohol metabolizing enzymes","volume":"49","author":"Agarwal","year":"2001","journal-title":"Pathol. Biol."},{"issue":"10","key":"10.1016\/j.alcohol.2007.07.009_bib2","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/j.oraloncology.2005.02.004","article-title":"Alcohol consumption and risk of laryngeal cancer","volume":"41","author":"Altieri","year":"2005","journal-title":"Oral Oncol."},{"issue":"4","key":"10.1016\/j.alcohol.2007.07.009_bib3","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1111\/j.1530-0277.1983.tb05495.x","article-title":"Behavioral and physiological effects of ethanol in high-risk and control children: a pilot study","volume":"7","author":"Behar","year":"1983","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.alcohol.2007.07.009_bib4","series-title":"Chinese herbal medicine materia medica","author":"Bensky","year":"2004"},{"issue":"1","key":"10.1016\/j.alcohol.2007.07.009_bib5","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/BF01884248","article-title":"Influence of a prolonged treatment with disulfiram and D(-)penicillamine on nitrosodiethylamine-induced biological and biochemical effects in rats. I. Investigations on the drug metabolizing system","volume":"109","author":"Bertram","year":"1985","journal-title":"J. Cancer Res. Clin. Oncol."},{"issue":"5","key":"10.1016\/j.alcohol.2007.07.009_bib6","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1023\/A:1024991618398","article-title":"Micronutrients and laryngeal cancer risk in Italy and Switzerland: a case-control study","volume":"14","author":"Bidoli","year":"2003","journal-title":"Cancer Causes Control"},{"key":"10.1016\/j.alcohol.2007.07.009_bib7","series-title":"The complete German commission E monographs; therapeutic guide to herbal medicines","author":"Blumenthal","year":"1998"},{"issue":"1","key":"10.1016\/j.alcohol.2007.07.009_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/aje\/kwh003","article-title":"Pooled analysis of alcohol dehydrogenase genotypes and head and neck cancer: a HuGE review","volume":"159","author":"Brennan","year":"2004","journal-title":"Am. J. Epidemiol."},{"issue":"3","key":"10.1016\/j.alcohol.2007.07.009_bib9","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.alcohol.2005.03.009","article-title":"DNA adducts from acetaldehyde: implications for alcohol-related carcinogenesis","volume":"35","author":"Brooks","year":"2005","journal-title":"Alcohol"},{"issue":"3","key":"10.1016\/j.alcohol.2007.07.009_bib10","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1111\/j.1530-0277.1983.tb05459.x","article-title":"Alcohol-induced euphoria enhanced by disulfiram and calcium carbimide","volume":"7","author":"Brown","year":"1983","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"9","key":"10.1016\/j.alcohol.2007.07.009_bib11","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S1470-2045(05)70303-X","article-title":"Acetaldehyde links alcohol consumption to cancer","volume":"6","author":"Burton","year":"2005","journal-title":"Lancet Oncol."},{"issue":"1","key":"10.1016\/j.alcohol.2007.07.009_bib12","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0304-3835(91)90044-I","article-title":"Effects of synthetic and naturally occurring flavonoids on benzo[a]pyrene metabolism by hepatic microsomes prepared from rats treated with cytochrome P-450 inducers","volume":"60","author":"Chae","year":"1991","journal-title":"Cancer Lett."},{"issue":"5","key":"10.1016\/j.alcohol.2007.07.009_bib13","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1093\/alcalc\/agg106","article-title":"Investigation of alcohol metabolizing enzyme genes in Chinese alcoholics with avascular necrosis of hip joint, pancreatitis and cirrhosis of the liver","volume":"38","author":"Chao","year":"2003","journal-title":"Alcohol Alcohol."},{"issue":"2","key":"10.1016\/j.alcohol.2007.07.009_bib14","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0272-0590(90)90205-X","article-title":"Ethylene dichloride: the influence of disulfiram or ethanol on oncogenicity, metabolism, and DNA covalent binding in rats","volume":"14","author":"Cheever","year":"1990","journal-title":"Fundam. Appl. Toxicol."},{"issue":"1","key":"10.1016\/j.alcohol.2007.07.009_bib15","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1006\/bbrc.1999.0943","article-title":"Expression and localization of human alcohol and aldehyde dehydrogenase enzymes in skin","volume":"261","author":"Cheung","year":"1999","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"10","key":"10.1016\/j.alcohol.2007.07.009_bib16","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1248\/bpb.25.1328","article-title":"Antithrombotic and antiallergic activities of daidzein, a metabolite of puerarin and daidzin produced by human intestinal microflora","volume":"25","author":"Choo","year":"2002","journal-title":"Biol. Pharm. Bull."},{"issue":"5","key":"10.1016\/j.alcohol.2007.07.009_bib17","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1002\/ijc.2910600508","article-title":"Diet, alcohol, smoking and cancer of the upper aerodigestive tract: a prospective study among Hawaii Japanese men","volume":"60","author":"Chyou","year":"1995","journal-title":"Int. J. Cancer"},{"issue":"2","key":"10.1016\/j.alcohol.2007.07.009_bib18","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1207\/s15327914nc5002_6","article-title":"Chemoprotection against N-nitrosomethylbenzylamine-induced mutation in the rat esophagus","volume":"50","author":"de Boer","year":"2004","journal-title":"Nutr. Cancer"},{"issue":"3","key":"10.1016\/j.alcohol.2007.07.009_bib19","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0741-8329(95)02052-7","article-title":"Expression and activities of class IV alcohol dehydrogenase and class III aldehyde dehydrogenase in human mouth","volume":"13","author":"Dong","year":"1996","journal-title":"Alcohol"},{"issue":"3","key":"10.1016\/j.alcohol.2007.07.009_bib20","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0306-4603(93)90030-D","article-title":"Hangover moderates the association between personality and drinking problems","volume":"18","author":"Earleywine","year":"1993","journal-title":"Addict. Behav."},{"issue":"4","key":"10.1016\/j.alcohol.2007.07.009_bib21","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/0306-4603(93)90058-H","article-title":"Personality risk for alcoholism covaries with hangover symptoms","volume":"18","author":"Earleywine","year":"1993","journal-title":"Addict. Behav."},{"issue":"5 Suppl","key":"10.1016\/j.alcohol.2007.07.009_bib22","doi-asserted-by":"crossref","first-page":"15S","DOI":"10.1111\/j.1530-0277.2001.tb02369.x","article-title":"The role of acetaldehyde in the actions of alcohol (update 2000)","volume":"25","author":"Eriksson","year":"2001","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"1\u20132","key":"10.1016\/j.alcohol.2007.07.009_bib23","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/adic.200690002","article-title":"Separation and determination of isoflavonoids in several kudzu samples by high-performance capillary electrophoresis (HPCE)","volume":"96","author":"Fang","year":"2006","journal-title":"Ann. Chim."},{"issue":"5 Suppl","key":"10.1016\/j.alcohol.2007.07.009_bib24","doi-asserted-by":"crossref","first-page":"2436","DOI":"10.1002\/1097-0142(197711)40:5+<2436::AID-CNCR2820400908>3.0.CO;2-U","article-title":"Investigations into the metabolism and mode of action of the colon carcinogens 1,2-dimethylhydrazine and azoxymethane","volume":"40","author":"Fiala","year":"1977","journal-title":"Cancer"},{"issue":"9","key":"10.1016\/j.alcohol.2007.07.009_bib25","doi-asserted-by":"crossref","first-page":"2227","DOI":"10.1002\/1097-0142(19921101)70:9<2227::AID-CNCR2820700902>3.0.CO;2-Z","article-title":"Risk factors for cancer of the tongue and the mouth. A case-control study from northern Italy","volume":"70","author":"Franceschi","year":"1992","journal-title":"Cancer"},{"key":"10.1016\/j.alcohol.2007.07.009_bib26","first-page":"519","article-title":"Influence of disulfiram on the metabolism of N-nitrosodiethylamine","volume":"57","author":"Frank","year":"1984","journal-title":"IARC Sci. Publ."},{"issue":"3","key":"10.1016\/j.alcohol.2007.07.009_bib27","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1093\/annonc\/mdj107","article-title":"Folate intake and squamous-cell carcinoma of the oesophagus in Italian and Swiss men","volume":"17","author":"Galeone","year":"2006","journal-title":"Ann. Oncol."},{"issue":"20","key":"10.1016\/j.alcohol.2007.07.009_bib28","doi-asserted-by":"crossref","first-page":"3320","DOI":"10.1021\/jm0101390","article-title":"Synthesis of potential antidipsotropic isoflavones: inhibitors of the mitochondrial monoamine oxidase-aldehyde dehydrogenase pathway","volume":"44","author":"Gao","year":"2001","journal-title":"J. Med. Chem."},{"issue":"18","key":"10.1016\/j.alcohol.2007.07.009_bib29","doi-asserted-by":"crossref","first-page":"4069","DOI":"10.1016\/S0968-0896(03)00397-3","article-title":"Synthesis of daidzin analogues as potential agents for alcohol abuse","volume":"11","author":"Gao","year":"2003","journal-title":"Bioorg. Med. Chem."},{"issue":"8","key":"10.1016\/j.alcohol.2007.07.009_bib30","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/0006-3223(94)00361-6","article-title":"Behavioral, physiological, and pharmacological interaction of cocaine and disulfiram in humans","volume":"37","author":"Hameedi","year":"1995","journal-title":"Biol. Psychiatry"},{"issue":"1\u20132","key":"10.1016\/j.alcohol.2007.07.009_bib31","first-page":"107","article-title":"Mechanism of alcohol sensitivity and disulfiram-ethanol reaction","volume":"3","author":"Harada","year":"1982","journal-title":"Subst. Alcohol Actions Misuse"},{"issue":"11","key":"10.1016\/j.alcohol.2007.07.009_bib32","doi-asserted-by":"crossref","first-page":"4017","DOI":"10.1210\/jc.84.11.4017","article-title":"Two-week dietary soy supplementation has an estrogenic effect on normal premenopausal breast","volume":"84","author":"Hargreaves","year":"1999","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"2","key":"10.1016\/j.alcohol.2007.07.009_bib33","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0006-2952(94)00491-9","article-title":"Inhibition of rat liver low Km aldehyde dehydrogenase by thiocarbamate herbicides. Occupational implications","volume":"49","author":"Hart","year":"1995","journal-title":"Biochem. Pharmacol."},{"issue":"2","key":"10.1016\/j.alcohol.2007.07.009_bib34","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/0014-5793(84)80807-8","article-title":"Human liver mitochondrial aldehyde dehydrogenase: a C-terminal segment positions and defines the structure corresponding to the one reported to differ in the Oriental enzyme variant","volume":"173","author":"Hempel","year":"1984","journal-title":"FEBS Lett."},{"issue":"2","key":"10.1016\/j.alcohol.2007.07.009_bib35","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1207\/s15327914nc4902_1","article-title":"Reports: plasma and dietary phytoestrogens and risk of premalignant lesions of the cervix","volume":"49","author":"Hernandez","year":"2004","journal-title":"Nutr. Cancer"},{"issue":"6","key":"10.1016\/j.alcohol.2007.07.009_bib36","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1111\/j.1530-0277.1996.tb01950.x","article-title":"Daidzin decreases ethanol consumption in rats","volume":"20","author":"Heyman","year":"1996","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"3","key":"10.1016\/j.alcohol.2007.07.009_bib37","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/j.1530-0277.1996.tb01080.x","article-title":"Alcohol and aldehyde dehydrogenase genotypes and drinking behavior in Japanese","volume":"20","author":"Higuchi","year":"1996","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"22","key":"10.1016\/j.alcohol.2007.07.009_bib38","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1093\/jnci\/89.22.1692","article-title":"Effects of acetaldehyde on cell regeneration and differentiation of the upper gastrointestinal tract mucosa","volume":"89","author":"Homann","year":"1997","journal-title":"J. Natl. Cancer Inst."},{"issue":"4","key":"10.1016\/j.alcohol.2007.07.009_bib39","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1093\/carcin\/21.4.663","article-title":"Increased salivary acetaldehyde levels in heavy drinkers and smokers: a microbiological approach to oral cavity cancer","volume":"21","author":"Homann","year":"2000","journal-title":"Carcinogenesis"},{"issue":"2","key":"10.1016\/j.alcohol.2007.07.009_bib40","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S1368-8375(00)00076-2","article-title":"Poor dental status increases acetaldehyde production from ethanol in saliva: a possible link to increased oral cancer risk among heavy drinkers","volume":"37","author":"Homann","year":"2001","journal-title":"Oral Oncol."},{"issue":"2","key":"10.1016\/j.alcohol.2007.07.009_bib41","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/(SICI)1097-0215(20000415)86:2<169::AID-IJC4>3.0.CO;2-3","article-title":"Microbially produced acetaldehyde from ethanol may increase the risk of colon cancer via folate deficiency","volume":"86","author":"Homann","year":"2000","journal-title":"Int. J. Cancer"},{"issue":"4","key":"10.1016\/j.alcohol.2007.07.009_bib42","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1097\/00004836-199712000-00003","article-title":"Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and human esophageal squamous cell carcinoma susceptibility","volume":"25","author":"Hori","year":"1997","journal-title":"J. Clin. Gastroenterol."},{"issue":"4","key":"10.1016\/j.alcohol.2007.07.009_bib43","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1023\/A:1008995606699","article-title":"Assessing phytoestrogen exposure in epidemiologic studies: development of a database (United States)","volume":"11","author":"Horn-Ross","year":"2000","journal-title":"Cancer Causes Control"},{"issue":"6","key":"10.1016\/j.alcohol.2007.07.009_bib44","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1111\/j.1440-1746.2004.03346.x","article-title":"Association between diet and esophageal cancer in Taiwan","volume":"19","author":"Hung","year":"2004","journal-title":"J. Gastroenterol. Hepatol."},{"issue":"5","key":"10.1016\/j.alcohol.2007.07.009_bib45","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1093\/carcin\/4.5.617","article-title":"The effect of disulfiram on the carcinogenicity of N-butyl-N-(3-carboxypropyl)nitrosamine in the rat","volume":"4","author":"Irving","year":"1983","journal-title":"Carcinogenesis"},{"issue":"5","key":"10.1016\/j.alcohol.2007.07.009_bib46","doi-asserted-by":"crossref","first-page":"185","DOI":"10.2188\/jea.16.185","article-title":"Smoking, alcohol drinking, green tea consumption and the risk of esophageal cancer in Japanese men","volume":"16","author":"Ishikawa","year":"2006","journal-title":"J. Epidemiol."},{"issue":"4","key":"10.1016\/j.alcohol.2007.07.009_bib47","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1254\/jjp.87.338","article-title":"Protective effects of Puerariae flos against ethanol-induced apoptosis on human neuroblastoma cell line SK-N-MC","volume":"87","author":"Jang","year":"2001","journal-title":"Jpn. J. Pharmacol."},{"issue":"2","key":"10.1016\/j.alcohol.2007.07.009_bib48","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1093\/jn\/132.2.238","article-title":"Soymilk products affect ethanol absorption and metabolism in rats during acute and chronic ethanol intake","volume":"132","author":"Kano","year":"2002","journal-title":"J. Nutr."},{"issue":"5","key":"10.1016\/j.alcohol.2007.07.009_bib49","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1073\/pnas.94.5.1675","article-title":"Daidzin inhibits mitochondrial aldehyde dehydrogenase and suppresses ethanol intake of Syrian golden hamsters","volume":"94","author":"Keung","year":"1997","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"4","key":"10.1016\/j.alcohol.2007.07.009_bib50","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1073\/pnas.90.4.1247","article-title":"Daidzin: a potent, selective inhibitor of human mitochondrial aldehyde dehydrogenase","volume":"90","author":"Keung","year":"1993","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"4","key":"10.1016\/j.alcohol.2007.07.009_bib51","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/S0031-9422(97)00723-1","article-title":"Kudzu root: an ancient Chinese source of modern antidipsotropic agents","volume":"47","author":"Keung","year":"1998","journal-title":"Phytochemistry"},{"issue":"14","key":"10.1016\/j.alcohol.2007.07.009_bib52","doi-asserted-by":"crossref","first-page":"4445","DOI":"10.1021\/bi9521093","article-title":"Possible role of liver cytosolic and mitochondrial aldehyde dehydrogenases in acetaldehyde metabolism","volume":"35","author":"Klyosov","year":"1996","journal-title":"Biochemistry"},{"issue":"1","key":"10.1016\/j.alcohol.2007.07.009_bib53","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0015-6264(80)90016-4","article-title":"Tumours induced in Fischer 344 rats by the feeding of disulfiram together with sodium nitrite","volume":"18","author":"Lijinsky","year":"1980","journal-title":"Food Cosmet. Toxicol."},{"issue":"4","key":"10.1016\/j.alcohol.2007.07.009_bib54","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1111\/j.1530-0277.1996.tb01668.x","article-title":"Isoflavonoid compounds extracted from Pueraria lobata suppress alcohol preference in a pharmacogenetic rat model of alcoholism","volume":"20","author":"Lin","year":"1996","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"5","key":"10.1016\/j.alcohol.2007.07.009_bib55","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1097\/01.ALC.0000163499.64347.92","article-title":"An extract of the Chinese herbal root kudzu reduces alcohol drinking by heavy drinkers in a naturalistic setting","volume":"29","author":"Lukas","year":"2005","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"2","key":"10.1016\/j.alcohol.2007.07.009_bib56","doi-asserted-by":"crossref","first-page":"70","DOI":"10.2188\/jea.12.70","article-title":"Aldehyde dehydrogenase 2 (ALDH2) genotype affects rectal cancer susceptibility due to alcohol consumption","volume":"12","author":"Matsuo","year":"2002","journal-title":"J. Epidemiol."},{"issue":"7","key":"10.1016\/j.alcohol.2007.07.009_bib57","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/S0006-2952(97)00686-2","article-title":"Inhibition of recombinant human mitochondrial aldehyde dehydrogenase by two intermediate metabolites of disulfiram","volume":"55","author":"Mays","year":"1998","journal-title":"Biochem. Pharmacol."},{"issue":"4","key":"10.1016\/j.alcohol.2007.07.009_bib58","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1093\/ajcn\/77.4.875","article-title":"Lack of significant genotoxicity of purified soy isoflavones (genistein, daidzein, and glycitein) in 20 patients with prostate cancer","volume":"77","author":"Miltyk","year":"2003","journal-title":"Am. J. Clin. Nutr."},{"issue":"4","key":"10.1016\/j.alcohol.2007.07.009_bib59","first-page":"297","article-title":"Higher consumption of green tea may enhance equol production","volume":"4","author":"Miyanaga","year":"2003","journal-title":"Asian Pac. J. Cancer Prev."},{"issue":"10","key":"10.1016\/j.alcohol.2007.07.009_bib60","doi-asserted-by":"crossref","first-page":"3168","DOI":"10.1093\/jn\/131.10.3168","article-title":"Phytoestrogen concentrations in serum from Japanese men and women over forty years of age","volume":"132","author":"Morton","year":"2002","journal-title":"J. Nutr."},{"issue":"6","key":"10.1016\/j.alcohol.2007.07.009_bib61","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1248\/yakushi1947.109.6_424","volume":"109","author":"Niiho","year":"1989","journal-title":"Yakugaku Zasshi"},{"issue":"21","key":"10.1016\/j.alcohol.2007.07.009_bib62","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1093\/jnci\/dji393","article-title":"Studies seek molecular clues on alcohol's role in cancer","volume":"97","author":"O'Hanlon","year":"2005","journal-title":"J. Natl. Cancer Inst."},{"issue":"6 Suppl","key":"10.1016\/j.alcohol.2007.07.009_bib63","doi-asserted-by":"crossref","first-page":"19S","DOI":"10.1111\/j.1530-0277.2001.tb02412.x","article-title":"Effect of ALDH2 and CYP2E1 gene polymorphisms on drinking behavior and alcoholic liver disease in Japanese male workers","volume":"25","author":"Okamoto","year":"2001","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"11","key":"10.1016\/j.alcohol.2007.07.009_bib64","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1093\/annonc\/mdg448","article-title":"Folate intake and risk of oral and pharyngeal cancer","volume":"14","author":"Pelucchi","year":"2003","journal-title":"Ann. Oncol."},{"issue":"3","key":"10.1016\/j.alcohol.2007.07.009_bib65","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1093\/alcalc\/agh057","article-title":"Alcohol and cancer","volume":"39","author":"Poschl","year":"2004","journal-title":"Alcohol Alcohol."},{"issue":"3","key":"10.1016\/j.alcohol.2007.07.009_bib66","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.alcohol.2005.05.001","article-title":"Mechanisms of alcohol-associated cancers: introduction and summary of the symposium","volume":"35","author":"Purohit","year":"2005","journal-title":"Alcohol"},{"issue":"4","key":"10.1016\/j.alcohol.2007.07.009_bib67","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1002\/ijc.20293","article-title":"Synergistic effect of alcohol drinking and smoking on in vivo acetaldehyde concentration in saliva","volume":"111","author":"Salaspuro","year":"2004","journal-title":"Int. J. Cancer"},{"issue":"3","key":"10.1016\/j.alcohol.2007.07.009_bib68","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1093\/ajcn\/76.3.588","article-title":"Pharmacokinetics of the glucuronide and sulfate conjugates of genistein and daidzein in men and women after consumption of a soy beverage","volume":"76","author":"Shelnutt","year":"2002","journal-title":"Am. J. Clin. Nutr."},{"issue":"1","key":"10.1016\/j.alcohol.2007.07.009_bib69","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/jbt.10057","article-title":"Human aldehyde dehydrogenases: potential pathological, pharmacological, and toxicological impact","volume":"17","author":"Sladek","year":"2003","journal-title":"J. Biochem. Mol. Toxicol."},{"issue":"1","key":"10.1016\/j.alcohol.2007.07.009_bib70","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0306-4603(98)00002-1","article-title":"Familial risk for alcoholism and hangover symptoms","volume":"24","author":"Span","year":"1999","journal-title":"Addict. Behav."},{"issue":"1","key":"10.1016\/j.alcohol.2007.07.009_bib71","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1530-0277.1998.tb03624.x","article-title":"Relevance of both daily hassles and the ALDH2 genotype to problem drinking among Japanese male workers","volume":"22","author":"Takeshita","year":"1998","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"12","key":"10.1016\/j.alcohol.2007.07.009_bib72","first-page":"1946","article-title":"Convergent adaptation of human lactase persistence in Africa and Europe","volume":"38","author":"Tishkoff","year":"2006","journal-title":"Nat. Genet."},{"issue":"6","key":"10.1016\/j.alcohol.2007.07.009_bib73","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1136\/gut.2003.018994","article-title":"Increased cancer risk in heavy drinkers with the alcohol dehydrogenase 1C*1 allele, possibly due to salivary acetaldehyde","volume":"53","author":"Visapaa","year":"2004","journal-title":"Gut"},{"issue":"6","key":"10.1016\/j.alcohol.2007.07.009_bib74","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S0753-3322(02)00182-8","article-title":"Isoflavones for prevention of cancer, cardiovascular diseases, gynecological problems and possible immune potentiation","volume":"56","author":"Watanabe","year":"2002","journal-title":"Biomed. Pharmacother."},{"issue":"6","key":"10.1016\/j.alcohol.2007.07.009_bib75","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1111\/j.1530-0277.1994.tb01448.x","article-title":"Daidzin, an antioxidant isoflavonoid, decreases blood alcohol levels and shortens sleep time induced by ethanol intoxication","volume":"18","author":"Xie","year":"1992","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"10","key":"10.1016\/j.alcohol.2007.07.009_bib76","doi-asserted-by":"crossref","first-page":"2741","DOI":"10.1093\/jn\/131.10.2741","article-title":"Validity and reproducibility of a self-administered food-frequency questionnaire to assess isoflavone intake in a Japanese population in comparison with dietary records and blood and urine isoflavones","volume":"131","author":"Yamamoto","year":"2001","journal-title":"J. Nutr."},{"issue":"1","key":"10.1016\/j.alcohol.2007.07.009_bib77","first-page":"23","article-title":"Pharmacological studies on Puerariae flos. IV: effects of Pueraria thomsonii dried flower extracts on blood ethanol and acetaldehyde levels in humans","volume":"22","author":"Yamazaki","year":"2002","journal-title":"Int. J. Clin. Pharmacol. Res."},{"issue":"3","key":"10.1016\/j.alcohol.2007.07.009_bib78","first-page":"256","article-title":"Esophageal cancer risk by ALDH2 and ADH2 polymorphisms and alcohol consumption: exploration of gene-environment and gene-gene interactions","volume":"6","author":"Yang","year":"2005","journal-title":"Asian Pac. J. Cancer Prev."},{"issue":"2","key":"10.1016\/j.alcohol.2007.07.009_bib79","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1111\/j.1530-0277.1993.tb00779.x","article-title":"Alcohol and aldehyde dehydrogenases in human esophagus: comparison with the stomach enzyme activities","volume":"17","author":"Yin","year":"1993","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"2","key":"10.1016\/j.alcohol.2007.07.009_bib80","first-page":"99","article-title":"Esophageal cancer and aldehyde dehydrogenase-2 genotypes in Japanese males","volume":"5","author":"Yokoyama","year":"1996","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"issue":"10","key":"10.1016\/j.alcohol.2007.07.009_bib81","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1002\/(SICI)1097-0142(19960515)77:10<1986::AID-CNCR4>3.0.CO;2-F","article-title":"Multiple primary esophageal and concurrent upper aerodigestive tract cancer and the aldehyde dehydrogenase-2 genotype of Japanese alcoholics","volume":"77","author":"Yokoyama","year":"1996","journal-title":"Cancer"},{"issue":"8","key":"10.1016\/j.alcohol.2007.07.009_bib82","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1093\/carcin\/19.8.1383","article-title":"Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics","volume":"19","author":"Yokoyama","year":"1998","journal-title":"Carcinogenesis"},{"issue":"3","key":"10.1016\/j.alcohol.2007.07.009_bib83","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1002\/(SICI)1097-0215(19961104)68:3<313::AID-IJC8>3.0.CO;2-4","article-title":"Cancer screening of upper aerodigestive tract in Japanese alcoholics with reference to drinking and smoking habits and aldehyde dehydrogenase-2 genotype","volume":"68","author":"Yokoyama","year":"1996","journal-title":"Int. J. Cancer"},{"issue":"7","key":"10.1016\/j.alcohol.2007.07.009_bib84","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1097\/01.ALC.0000172457.62535.EE","article-title":"Hangover susceptibility in relation to aldehyde dehydrogenase-2 genotype, alcohol flushing, and mean corpuscular volume in Japanese workers","volume":"29","author":"Yokoyama","year":"2005","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"9","key":"10.1016\/j.alcohol.2007.07.009_bib85","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1097\/01.ALC.0000085589.47243.8D","article-title":"Mean corpuscular volume and the aldehyde dehydrogenase-2 genotype in male Japanese workers","volume":"27","author":"Yokoyama","year":"2003","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"4","key":"10.1016\/j.alcohol.2007.07.009_bib86","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1097\/01.ALC.0000158842.24218.03","article-title":"Epidemiological evidence that acetaldehyde plays a significant role in the development of decreased serum folate concentration and elevated mean corpuscular volume in alcohol drinkers","volume":"29","author":"Yokoyama","year":"2005","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"1","key":"10.1016\/j.alcohol.2007.07.009_bib87","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0741-8329(85)90024-2","article-title":"Molecular abnormality and cDNA cloning of human aldehyde dehydrogenases","volume":"2","author":"Yoshida","year":"1985","journal-title":"Alcohol"}],"container-title":["Alcohol"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741832907001371?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741832907001371?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,5]],"date-time":"2019-05-05T03:30:51Z","timestamp":1557027051000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0741832907001371"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11]]},"references-count":87,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["S0741832907001371"],"URL":"https:\/\/doi.org\/10.1016\/j.alcohol.2007.07.009","relation":{},"ISSN":["0741-8329"],"issn-type":[{"value":"0741-8329","type":"print"}],"subject":[],"published":{"date-parts":[[2007,11]]}}}