{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T02:59:47Z","timestamp":1776999587493,"version":"3.51.4"},"reference-count":34,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T00:00:00Z","timestamp":1243814400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Alcohol"],"published-print":{"date-parts":[[2009,6]]},"DOI":"10.1016\/j.alcohol.2009.02.007","type":"journal-article","created":{"date-parts":[[2009,4,18]],"date-time":"2009-04-18T08:58:29Z","timestamp":1240045109000},"page":"259-264","source":"Crossref","is-referenced-by-count":13,"title":["Effects of heroin-assisted treatment on alcohol consumption: findings of the German randomized controlled trial"],"prefix":"10.1016","volume":"43","author":[{"given":"C.","family":"Haasen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.J.","family":"Eiroa-Orosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Verthein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Soyka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Dilg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Sch\u00e4fer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Reimer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.alcohol.2009.02.007_bib1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0741-8329(01)00165-3","article-title":"Carbohydrate-deficient transferrin for detection and monitoring of sustained heavy drinking: what have we learned? Where do we go from here?","volume":"25","author":"Anton","year":"2001","journal-title":"Alcohol"},{"key":"10.1016\/j.alcohol.2009.02.007_bib2","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1111\/j.1530-0277.1993.tb00819.x","article-title":"Correlates of alcohol use among methadone patients","volume":"17","author":"el-Bassel","year":"1993","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.alcohol.2009.02.007_bib3","doi-asserted-by":"crossref","first-page":"489","DOI":"10.3109\/16066359809004367","article-title":"Eating too little, smoking and drinking too much: wider lifestyle problems among methadone maintenance patients","volume":"6","author":"Best","year":"1998","journal-title":"Addict. Res. Theory"},{"key":"10.1016\/j.alcohol.2009.02.007_bib4","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0740-5472(87)90005-5","article-title":"The treatment of alcoholic methadone patients: a review","volume":"4","author":"Bickel","year":"1987","journal-title":"J. Subst. Abuse Treat."},{"key":"10.1016\/j.alcohol.2009.02.007_bib5","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1136\/bmj.327.7410.310","article-title":"Medical prescription of heroin to treatment resistant heroin addicts: two randomised controlled trials","volume":"327","author":"van den Brink","year":"2003","journal-title":"Br. Med. J."},{"key":"10.1016\/j.alcohol.2009.02.007_bib6","doi-asserted-by":"crossref","first-page":"417","DOI":"10.15288\/jsa.1995.56.417","article-title":"Heavy drinking in a population of methadone-maintained clients","volume":"56","author":"Chatham","year":"1995","journal-title":"J. Stud. Alcohol"},{"key":"10.1016\/j.alcohol.2009.02.007_bib7","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/1477-7517-3-31","article-title":"Therapeutic challenges in hepatitis C-infected injection drug using patients","volume":"3","author":"Cooper","year":"2006","journal-title":"Harm Reduct. J."},{"key":"10.1016\/j.alcohol.2009.02.007_bib8","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1111\/j.1360-0443.1992.tb02719.x","article-title":"Development and validation of a multi-dimensional instrument for assessing outcome of treatment among opiate users: the Opiate Treatment Index","volume":"87","author":"Darke","year":"1992","journal-title":"Br. J. Addict."},{"key":"10.1016\/j.alcohol.2009.02.007_bib9","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1111\/j.1360-0443.1991.tb01707.x","article-title":"A scale for estimating the health status of opioid users","volume":"86","author":"Darke","year":"1991","journal-title":"Addiction"},{"key":"10.1016\/j.alcohol.2009.02.007_bib10","doi-asserted-by":"crossref","DOI":"10.1055\/s-2007-970428","article-title":"\u201cSchwerstabh\u00e4ngige\u201d\u2014Die Teilnehmer des Modellprojekts zur heroingest\u00fctzten Behandlung","volume":"8","author":"Degkwitz","year":"2007","journal-title":"Suchttherapie"},{"key":"10.1016\/j.alcohol.2009.02.007_bib11","series-title":"SCL-90-R: Administration, Scoring and Procedures Manual","author":"Derogatis","year":"1994"},{"key":"10.1016\/j.alcohol.2009.02.007_bib12","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1007\/s11524-007-9198-y","article-title":"Heroin-assisted treatment (HAT) a decade later: a brief update on science and politics","volume":"84","author":"Fischer","year":"2007","journal-title":"J. Urban Health"},{"key":"10.1016\/j.alcohol.2009.02.007_bib13","series-title":"Nach der 5. Auflage der amerikanischen Version von McLellan und der Europ\u00e4ischen Version des ASI","year":"1999"},{"key":"10.1016\/j.alcohol.2009.02.007_bib14","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1192\/bjp.bp.106.026112","article-title":"Heroin-assisted treatment for opioid dependence: randomised controlled trial","volume":"191","author":"Haasen","year":"2007","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.alcohol.2009.02.007_bib15","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1111\/j.1360-0443.2008.02134.x","article-title":"Does alcohol increase the risk of overdose death: the need for a translational approach","volume":"103","author":"Hickman","year":"2008","journal-title":"Addiction"},{"key":"10.1016\/j.alcohol.2009.02.007_bib16","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0740-5472(01)00198-2","article-title":"Excessive alcohol consumption and drinking expectations among clients in methadone maintenance","volume":"21","author":"Hillebrand","year":"2001","journal-title":"J. Subst. Abuse Treat."},{"key":"10.1016\/j.alcohol.2009.02.007_bib17","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1111\/j.1360-0443.2005.01216.x","volume":"100","author":"Hock","year":"2005","journal-title":"Addiction"},{"key":"10.1016\/j.alcohol.2009.02.007_bib18","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1159\/000259089","article-title":"EuropASI: European adaptation of a multidimensional assessment instrument for drug and alcohol dependence","volume":"1","author":"Kokkevi","year":"1995","journal-title":"Eur. Addict. Res."},{"key":"10.1016\/j.alcohol.2009.02.007_bib19","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1023\/A:1005555519831","article-title":"Sex, drugs, and HIV: does methadone maintenance reduce drug use and risky sexual behavior?","volume":"23","author":"Lollis","year":"2000","journal-title":"J. Behav. Med."},{"key":"10.1016\/j.alcohol.2009.02.007_bib20","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.jsat.2006.04.007","article-title":"Controlled trial of prescribed heroin in the treatment of opioid addiction","volume":"31","author":"March","year":"2006","journal-title":"J. Subst. Abuse Treat."},{"key":"10.1016\/j.alcohol.2009.02.007_bib21","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0740-5472(92)90062-S","article-title":"The fifth edition of the addiction severity index","volume":"9","author":"McLellan","year":"1992","journal-title":"J. Subst. Abuse Treat."},{"key":"10.1016\/j.alcohol.2009.02.007_bib22","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1177\/0306624X00446004","article-title":"Methadone clients, crime, and substance use","volume":"44","author":"Patterson","year":"2000","journal-title":"Int. J. Offender Ther. Comp. Criminol."},{"key":"10.1016\/j.alcohol.2009.02.007_bib23","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1093\/jat\/23.7.570","article-title":"The role of alcohol abuse in the etiology of heroin-related deaths. Evidence for pharmacokinetic interactions between heroin and alcohol","volume":"23","author":"Polettini","year":"1999","journal-title":"J. Anal. Toxicol."},{"key":"10.1016\/j.alcohol.2009.02.007_bib24","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1016\/S0140-6736(01)06529-1","article-title":"Feasibility, safety, and efficacy of injectable heroin prescription for refractory opioid addicts: a follow-up study","volume":"358","author":"Rehm","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.alcohol.2009.02.007_bib25","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jsat.2006.03.003","article-title":"Predicting DSM-IV dependence diagnoses from Addiction Severity Index composite scores","volume":"31","author":"Rikoon","year":"2006","journal-title":"J. Subst. Abuse Treat."},{"key":"10.1016\/j.alcohol.2009.02.007_bib26","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1037\/0893-164X.22.4.544","article-title":"Abstinence-contingent reinforcement and engagement in non-drug-related activities among illicit drug abusers","volume":"22","author":"Rogers","year":"2008","journal-title":"Psychol. Addict. Behav."},{"key":"10.1016\/j.alcohol.2009.02.007_bib27","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1080\/10550490050172218","article-title":"Importance of identifying cocaine and alcohol dependent methadone clients","volume":"9","author":"Rowan-Szal","year":"2000","journal-title":"Am. J. Addict."},{"key":"10.1016\/j.alcohol.2009.02.007_bib28","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1520\/JFS12902J","article-title":"The role of ethanol abuse in the etiology of heroin related deaths","volume":"35","author":"Ruttenber","year":"1990","journal-title":"J. Forensic Sci."},{"key":"10.1016\/j.alcohol.2009.02.007_bib29","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.jsat.2007.04.001","article-title":"The effect of methadone maintenance treatment on alcohol consumption: a systematic review","volume":"34","author":"Srivastava","year":"2008","journal-title":"J. Subst. Abuse Treat."},{"key":"10.1016\/j.alcohol.2009.02.007_bib30","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1038\/sj.clpt.6100508","article-title":"Contingency management: utility in the treatment of drug abuse disorders","volume":"83","author":"Stitzer","year":"2008","journal-title":"Clin. Pharmacol. Ther."},{"key":"10.1016\/j.alcohol.2009.02.007_bib31","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0376-8716(02)00010-8","article-title":"Treating hepatitis C in methadone maintenance patients: an interim analysis","volume":"67","author":"Sylvestre","year":"2002","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.alcohol.2009.02.007_bib32","volume":"Vol. 1","author":"Uchtenhagen","year":"1999"},{"key":"10.1016\/j.alcohol.2009.02.007_bib33","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1111\/j.1360-0443.2008.02185.x","article-title":"Long-term effects of heroin-assisted treatment in Germany","volume":"103","author":"Verthein","year":"2008","journal-title":"Addiction"},{"key":"10.1016\/j.alcohol.2009.02.007_bib34","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1046\/j.1360-0443.2000.951778.x","article-title":"Deaths in methadone maintenance treatment in New South Wales, Australia 1990-1995","volume":"95","author":"Zador","year":"2000","journal-title":"Addiction"}],"container-title":["Alcohol"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741832909000354?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741832909000354?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,3,12]],"date-time":"2024-03-12T18:36:50Z","timestamp":1710268610000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0741832909000354"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,6]]}},"alternative-id":["S0741832909000354"],"URL":"https:\/\/doi.org\/10.1016\/j.alcohol.2009.02.007","relation":{},"ISSN":["0741-8329"],"issn-type":[{"value":"0741-8329","type":"print"}],"subject":[],"published":{"date-parts":[[2009,6]]}}}