{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T02:57:12Z","timestamp":1777517832904,"version":"3.51.4"},"reference-count":69,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Alcohol"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1016\/j.alcohol.2012.03.001","type":"journal-article","created":{"date-parts":[[2012,5,7]],"date-time":"2012-05-07T15:04:14Z","timestamp":1336403054000},"page":"463-471","source":"Crossref","is-referenced-by-count":39,"title":["The \u03b16 nicotinic acetylcholine receptor subunit influences ethanol-induced sedation"],"prefix":"10.1016","volume":"46","author":[{"given":"Helen M.","family":"Kamens","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole R.","family":"Hoft","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan J.","family":"Cox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jill H.","family":"Miyamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marissa A.","family":"Ehringer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.alcohol.2012.03.001_bib1","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1016\/j.biocel.2006.01.006","article-title":"Molecular mechanisms and binding site locations for noncompetitive antagonists of nicotinic acetylcholine receptors","volume":"38","author":"Arias","year":"2006","journal-title":"International Journal of Biochemistry & Cell Biology"},{"key":"10.1016\/j.alcohol.2012.03.001_bib2","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1097\/01.ALC.0000091226.18969.B9","article-title":"Reverse selection for differential response to the locomotor stimulant effects of ethanol provides evidence for pleiotropic genetic influence on locomotor response to other drugs of abuse","volume":"27","author":"Bergstrom","year":"2003","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2012.03.001_bib3","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.pbb.2010.05.015","article-title":"Inhibitory influence of mecamylamine on the development and the expression of ethanol-induced locomotor sensitization in mice","volume":"96","author":"Bhutada","year":"2010","journal-title":"Pharmacology Biochemistry and Behaviour"},{"key":"10.1016\/j.alcohol.2012.03.001_bib4","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1097\/FBP.0b013e328337be54","article-title":"Inhibitory influence of mecamylamine on ethanol withdrawal-induced symptoms in C57BL\/6J mice","volume":"21","author":"Bhutada","year":"2010","journal-title":"Behavioural Pharmacology"},{"key":"10.1016\/j.alcohol.2012.03.001_bib5","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0014-2999(96)00583-3","article-title":"Voluntary ethanol intake in the rat: effects of nicotinic acetylcholine receptor blockade or subchronic nicotine treatment","volume":"314","author":"Blomqvist","year":"1996","journal-title":"European Journal of Pharmacology"},{"key":"10.1016\/j.alcohol.2012.03.001_bib6","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0361-9230(92)90023-Q","article-title":"Ethanol-induced locomotor activity: involvement of central nicotinic acetylcholine receptors?","volume":"29","author":"Blomqvist","year":"1992","journal-title":"Brain Research Bulletin"},{"key":"10.1016\/j.alcohol.2012.03.001_bib7","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1097\/01.ALC.0000156116.40817.A2","article-title":"Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol","volume":"29","author":"Bowers","year":"2005","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2012.03.001_bib8","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1523\/JNEUROSCI.22-04-01208.2002","article-title":"Distribution and pharmacology of alpha 6-containing nicotinic acetylcholine receptors analyzed with mutant mice","volume":"22","author":"Champtiaux","year":"2002","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.alcohol.2012.03.001_bib9","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/npp.2010.191","article-title":"Partial agonists of the alpha3beta4* neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats","volume":"36","author":"Chatterjee","year":"2011","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.alcohol.2012.03.001_bib10","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.neubiorev.2004.08.002","article-title":"An analysis of the genetics of alcohol intoxication in inbred mice","volume":"28","author":"Crabbe","year":"2005","journal-title":"Neuroscience & Biobehavioral Reviews"},{"key":"10.1016\/j.alcohol.2012.03.001_bib11","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1007\/s10519-006-9067-6","article-title":"Effects of genetic and procedural variation on measurement of alcohol sensitivity in mouse inbred strains","volume":"36","author":"Crabbe","year":"2006","journal-title":"Behavior Genetics"},{"key":"10.1016\/j.alcohol.2012.03.001_bib12","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1152\/japplphysiol.00132.2003","article-title":"Genotypic differences in ethanol sensitivity in two tests of motor incoordination","volume":"95","author":"Crabbe","year":"2003","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.alcohol.2012.03.001_bib13","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1126\/science.284.5420.1670","article-title":"Genetics of mouse behavior: interactions with laboratory environment","volume":"284","author":"Crabbe","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.alcohol.2012.03.001_bib14","doi-asserted-by":"crossref","first-page":"11045","DOI":"10.1523\/JNEUROSCI.23-35-11045.2003","article-title":"The beta3 nicotinic receptor subunit: a component of alpha-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors","volume":"23","author":"Cui","year":"2003","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.alcohol.2012.03.001_bib15","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1093\/alcalc\/35.2.171","article-title":"Clinical correlates of cigarette smoking and nicotine dependence in alcohol-dependent men and women. The collaborative study group on the genetics of alcoholism","volume":"35","author":"Daeppen","year":"2000","journal-title":"Alcohol and Alcoholism"},{"key":"10.1016\/j.alcohol.2012.03.001_bib16","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1523\/JNEUROSCI.19-02-00549.1999","article-title":"Identification of an acute ethanol response quantitative trait locus on mouse chromosome 2","volume":"19","author":"Demarest","year":"1999","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.alcohol.2012.03.001_bib17","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.alcohol.2009.06.003","article-title":"Reduced alcohol consumption in mice with access to a running wheel","volume":"43","author":"Ehringer","year":"2009","journal-title":"Alcohol"},{"key":"10.1016\/j.alcohol.2012.03.001_bib18","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1002\/ajmg.b.31027","article-title":"Association of CHRN genes with \u201cdizziness\u201d to tobacco","volume":"153B","author":"Ehringer","year":"2010","journal-title":"American Journal of Medical Genetics Part B: Neuropsychiatric Genetics"},{"key":"10.1016\/j.alcohol.2012.03.001_bib19","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0741-8329(99)00099-3","article-title":"Peripheral involvement in nicotine-induced enhancement of ethanol intake","volume":"21","author":"Ericson","year":"2000","journal-title":"Alcohol"},{"key":"10.1016\/j.alcohol.2012.03.001_bib20","first-page":"162","article-title":"An epidemiologic analysis of co-occurring alcohol and tobacco use and disorders: findings from the national epidemiologic survey on alcohol and related conditions","volume":"29","author":"Falk","year":"2006","journal-title":"Alcohol Research & Health"},{"key":"10.1016\/j.alcohol.2012.03.001_bib21","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1159\/000219488","article-title":"Effects of mecamylamine on alcohol consumption and preference in male C57BL\/6J mice","volume":"83","author":"Farook","year":"2009","journal-title":"Pharmacology"},{"key":"10.1016\/j.alcohol.2012.03.001_bib22","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1111\/j.1530-0277.2002.tb02603.x","article-title":"The selectively bred high alcohol sensitivity (HAS) and low alcohol sensitivity (LAS) rats differ in sensitivity to nicotine","volume":"26","author":"de Fiebre","year":"2002","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2012.03.001_bib23","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0741-8329(90)90014-4","article-title":"Ethanol-nicotine interactions in long-sleep and short-sleep mice","volume":"7","author":"de Fiebre","year":"1990","journal-title":"Alcohol"},{"key":"10.1016\/j.alcohol.2012.03.001_bib24","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/0741-8329(87)90092-9","article-title":"Nicotine response and nicotinic receptors in long-sleep and short-sleep mice","volume":"4","author":"de Fiebre","year":"1987","journal-title":"Alcohol"},{"key":"10.1016\/j.alcohol.2012.03.001_bib25","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1111\/j.1530-0277.1991.tb01868.x","article-title":"Responses to cholinergic agonists of rats selectively bred for differential sensitivity to ethanol","volume":"15","author":"de Fiebre","year":"1991","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2012.03.001_bib26","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/j.neuroscience.2003.11.017","article-title":"Sex differences in the effect of ethanol injection and consumption on brain allopregnanolone levels in C57BL\/6 mice","volume":"123","author":"Finn","year":"2004","journal-title":"Neuroscience"},{"key":"10.1016\/j.alcohol.2012.03.001_bib27","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.alcohol.2011.11.005","article-title":"Transgenic over expression of nicotinic receptor alpha 5, alpha 3, and beta 4 subunit genes reduces ethanol intake in mice","volume":"46","author":"Gallego","year":"2012","journal-title":"Alcohol"},{"key":"10.1016\/j.alcohol.2012.03.001_bib28","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.tips.2006.07.004","article-title":"Brain nicotinic acetylcholine receptors: native subtypes and their relevance","volume":"27","author":"Gotti","year":"2006","journal-title":"Trends in Pharmacological Sciences"},{"key":"10.1016\/j.alcohol.2012.03.001_bib29","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/j.bcp.2007.07.032","article-title":"The subtypes of nicotinic acetylcholine receptors on dopaminergic terminals of mouse striatum","volume":"74","author":"Grady","year":"2007","journal-title":"Biochemical Pharmacology"},{"key":"10.1016\/j.alcohol.2012.03.001_bib30","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1038\/sj.mp.4001774","article-title":"Why do young women smoke? I. Direct and interactive effects of environment, psychological characteristics and nicotinic cholinergic receptor genes","volume":"11","author":"Greenbaum","year":"2006","journal-title":"Molecular Psychiatry"},{"key":"10.1016\/j.alcohol.2012.03.001_bib31","doi-asserted-by":"crossref","first-page":"10169","DOI":"10.1523\/JNEUROSCI.2601-10.2010","article-title":"Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption","volume":"30","author":"Hendrickson","year":"2010","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.alcohol.2012.03.001_bib32","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1007\/s00213-009-1488-5","article-title":"Modulation of ethanol drinking-in-the-dark by mecamylamine and nicotinic acetylcholine receptor agonists in C57BL\/6J mice","volume":"204","author":"Hendrickson","year":"2009","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.alcohol.2012.03.001_bib33","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1111\/j.1601-183X.2009.00495.x","article-title":"SNPs in CHRNA6 and CHRNB3 are associated with alcohol consumption in a nationally representative sample","volume":"8","author":"Hoft","year":"2009","journal-title":"Genes, Brain and Behavior"},{"key":"10.1016\/j.alcohol.2012.03.001_bib34","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1038\/npp.2008.122","article-title":"Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample","volume":"34","author":"Hoft","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.alcohol.2012.03.001_bib35","doi-asserted-by":"crossref","first-page":"4705","DOI":"10.1021\/jm040219e","article-title":"Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations","volume":"48","author":"Jensen","year":"2005","journal-title":"Journal Medicinal Chemistry"},{"key":"10.1016\/j.alcohol.2012.03.001_bib36","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1093\/alcalc\/agl049","article-title":"Role of the\u00a0subunit composition of central nicotinic acetylcholine receptors for the stimulatory and dopamine-enhancing effects of ethanol","volume":"41","author":"Jerlhag","year":"2006","journal-title":"Alcohol and Alcoholism"},{"key":"10.1016\/j.alcohol.2012.03.001_bib37","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1093\/alcalc\/agg122","article-title":"Strength of the relationship between tobacco smoking, nicotine dependence and the severity of alcohol dependence syndrome criteria in a population-based sample","volume":"38","author":"John","year":"2003","journal-title":"Alcohol and Alcoholism"},{"key":"10.1016\/j.alcohol.2012.03.001_bib38","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1007\/s00213-009-1759-1","article-title":"Modulation of ethanol consumption by genetic and pharmacological manipulation of nicotinic acetylcholine receptors in mice","volume":"208","author":"Kamens","year":"2010","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.alcohol.2012.03.001_bib39","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1111\/j.1530-0277.2010.01301.x","article-title":"The nicotinic acetylcholine receptor partial agonist varenicline increases the ataxic and sedative-hypnotic effects of acute ethanol administration in C57BL\/6J mice","volume":"34","author":"Kamens","year":"2010","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2012.03.001_bib40","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1037\/0735-7044.120.6.1356","article-title":"Ethanol-related traits in mice selectively bred for differential sensitivity to methamphetamine-induced activation","volume":"120","author":"Kamens","year":"2006","journal-title":"Behavioral Neuroscience"},{"key":"10.1016\/j.alcohol.2012.03.001_bib41","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1111\/j.1601-183X.2008.00444.x","article-title":"The alpha 3 subunit gene of the nicotinic acetylcholine receptor is a candidate gene for ethanol stimulation","volume":"8","author":"Kamens","year":"2009","journal-title":"Genes, Brain and Behavior"},{"key":"10.1016\/j.alcohol.2012.03.001_bib42","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s00213-007-0969-7","article-title":"A\u00a0role for neuronal nicotinic acetylcholine receptors in ethanol-induced stimulation, but not cocaine- or methamphetamine-induced stimulation","volume":"196","author":"Kamens","year":"2008","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.alcohol.2012.03.001_bib43","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1001\/archpsyc.64.11.1313","article-title":"Specificity of genetic and environmental risk factors for symptoms of cannabis, cocaine, alcohol, caffeine, and nicotine dependence","volume":"64","author":"Kendler","year":"2007","journal-title":"Archives of General Psychiatry"},{"issue":"Suppl.","key":"10.1016\/j.alcohol.2012.03.001_bib44","doi-asserted-by":"crossref","first-page":"S72","DOI":"10.1016\/j.brainres.2009.08.026","article-title":"Association of nAChR gene haplotypes with heavy alcohol use and body mass","volume":"1305","author":"Landgren","year":"2009","journal-title":"Brain Research"},{"key":"10.1016\/j.alcohol.2012.03.001_bib45","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.alcohol.2004.10.002","article-title":"Is an alpha-conotoxin MII-sensitive mechanism involved in the neurochemical, stimulatory, and rewarding effects of ethanol?","volume":"34","author":"Larsson","year":"2004","journal-title":"Alcohol"},{"key":"10.1016\/j.alcohol.2012.03.001_bib46","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0741-8329(02)00244-6","article-title":"Role of different nicotinic acetylcholine receptors in mediating behavioral and neurochemical effects of ethanol in mice","volume":"28","author":"Larsson","year":"2002","journal-title":"Alcohol"},{"key":"10.1016\/j.alcohol.2012.03.001_bib47","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1530-0277.2000.tb04585.x","article-title":"Involvement of nicotinic receptors in alcohol self-administration","volume":"24","author":"Le","year":"2000","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2012.03.001_bib48","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1111\/j.1530-0277.2008.00857.x","article-title":"Sensitivity and tolerance to the hypnotic and ataxic effects of ethanol in adolescent and adult C57BL\/6J and DBA\/2J mice","volume":"33","author":"Linsenbardt","year":"2009","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2012.03.001_bib49","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/s00213-007-0899-4","article-title":"Nicotinic acetylcholine receptors in the ventral tegmental area mediate the dopamine activating and reinforcing properties of ethanol cues","volume":"195","author":"Lof","year":"2007","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.alcohol.2012.03.001_bib50","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1111\/j.1530-0277.2002.tb02503.x","article-title":"Shared genetic vulnerability in alcohol and cigarette use and dependence","volume":"26","author":"Madden","year":"2002","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2012.03.001_bib51","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0740-5472(97)00049-4","article-title":"Nicotine dependence and withdrawal in alcoholic and nonalcoholic ever-smokers","volume":"14","author":"Marks","year":"1997","journal-title":"Journal of Substance Abuse Treatment"},{"key":"10.1016\/j.alcohol.2012.03.001_bib52","series-title":"Development of animal models as pharmacogenetic tools","first-page":"147","article-title":"Selective breeding for ethanol sensitivity: short-sleep and long-sleep mice","author":"McClearn","year":"1981"},{"key":"10.1016\/j.alcohol.2012.03.001_bib53","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1111\/j.1749-6632.1999.tb11330.x","article-title":"Molecular diversity of neuronal nicotinic acetylcholine receptors","volume":"868","author":"McGehee","year":"1999","journal-title":"Annals of the New York Academy of Sciences"},{"key":"10.1016\/j.alcohol.2012.03.001_bib54","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/BF02244259","article-title":"Response to selection for ethanol-induced locomotor activation: genetic analyses and selection response characterization","volume":"103","author":"Phillips","year":"1991","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.alcohol.2012.03.001_bib55","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1111\/j.1530-0277.1994.tb00062.x","article-title":"Localization of genes affecting alcohol drinking in mice","volume":"18","author":"Phillips","year":"1994","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2012.03.001_bib56","first-page":"593","article-title":"Forward, relaxed, and reverse selection for reduced and enhanced sensitivity to ethanol's locomotor stimulant effects in mice","volume":"26","author":"Phillips","year":"2002","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2012.03.001_bib57","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1124\/jpet.302.1.257","article-title":"A\u00a0novel method to assess initial sensitivity and acute functional tolerance to hypnotic effects of ethanol","volume":"302","author":"Ponomarev","year":"2002","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"10.1016\/j.alcohol.2012.03.001_bib58","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/0091-3057(75)90069-6","article-title":"Ethanol-induced mouse strain differences in locomotor activity","volume":"3","author":"Randall","year":"1975","journal-title":"Pharmacology Biochemistry and Behaviour"},{"key":"10.1016\/j.alcohol.2012.03.001_bib59","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1002\/med.10037","article-title":"Cholinergic nicotinic receptors: competitive ligands, allosteric modulators, and their potential applications","volume":"23","author":"Romanelli","year":"2003","journal-title":"Medicinal Research Reviews"},{"key":"10.1016\/j.alcohol.2012.03.001_bib60","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1093\/hmg\/ddl438","article-title":"Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs","volume":"16","author":"Saccone","year":"2007","journal-title":"Human Molecular Genetics"},{"key":"10.1016\/j.alcohol.2012.03.001_bib61","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1111\/j.1530-0277.1995.tb01606.x","article-title":"Bidirectional selective breeding for ethanol effects on locomotor activity: characterization of FAST and SLOW mice through selection generation 35","volume":"19","author":"Shen","year":"1995","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2012.03.001_bib62","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1111\/j.1530-0277.1986.tb05071.x","article-title":"Dose and route of administration alter the relative elimination of ethanol by long-sleep and short-sleep mice","volume":"10","author":"Smolen","year":"1986","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2012.03.001_bib63","doi-asserted-by":"crossref","first-page":"182","DOI":"10.15288\/jsa.1997.58.182","article-title":"Heavy consumption of cigarettes, alcohol and coffee in male twins","volume":"58","author":"Swan","year":"1997","journal-title":"Journal of Studies on Alcohol"},{"key":"10.1016\/j.alcohol.2012.03.001_bib64","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.neuroscience.2008.08.046","article-title":"Attenuation of ethanol-induced ataxia by alpha(4)beta(2) nicotinic acetylcholine receptor subtype in mouse cerebellum: a functional interaction","volume":"157","author":"Taslim","year":"2008","journal-title":"Neuroscience"},{"key":"10.1016\/j.alcohol.2012.03.001_bib65","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1038\/ng.573","article-title":"Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior","volume":"42","author":"Thorgeirsson","year":"2010","journal-title":"Nature Genetics"},{"key":"10.1016\/j.alcohol.2012.03.001_bib66","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1001\/archpsyc.56.7.655","article-title":"Common genetic vulnerability for nicotine and alcohol dependence in men","volume":"56","author":"True","year":"1999","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.alcohol.2012.03.001_bib67","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1080\/10673220127912","article-title":"The Harvard twin study of substance abuse: what we have learned","volume":"9","author":"Tsuang","year":"2001","journal-title":"Harvard Review of Psychiatry"},{"key":"10.1016\/j.alcohol.2012.03.001_bib68","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1016\/j.bcp.2011.06.026","article-title":"Recent advances in understanding nicotinic receptor signaling mechanisms that regulate drug self-administration behavior","volume":"82","author":"Tuesta","year":"2011","journal-title":"Biochemical Pharmacology"},{"key":"10.1016\/j.alcohol.2012.03.001_bib69","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1093\/hmg\/ddm344","article-title":"The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobacco","volume":"17","author":"Zeiger","year":"2008","journal-title":"Human Molecular Genetics"}],"container-title":["Alcohol"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741832912000535?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741832912000535?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,28]],"date-time":"2019-06-28T10:21:03Z","timestamp":1561717263000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0741832912000535"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":69,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S0741832912000535"],"URL":"https:\/\/doi.org\/10.1016\/j.alcohol.2012.03.001","relation":{},"ISSN":["0741-8329"],"issn-type":[{"value":"0741-8329","type":"print"}],"subject":[],"published":{"date-parts":[[2012,8]]}}}