{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T00:33:55Z","timestamp":1780706035059,"version":"3.54.1"},"reference-count":67,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["AA007573"],"award-info":[{"award-number":["AA007573"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["AA021651"],"award-info":[{"award-number":["AA021651"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["AA011605"],"award-info":[{"award-number":["AA011605"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["U54HD079124"],"award-info":[{"award-number":["U54HD079124"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["alcoholjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Alcohol"],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1016\/j.alcohol.2015.01.005","type":"journal-article","created":{"date-parts":[[2015,1,26]],"date-time":"2015-01-26T15:33:30Z","timestamp":1422286410000},"page":"207-217","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":60,"title":["Hypothalamic-pituitary-adrenal axis and behavioral dysfunction following early binge-like prenatal alcohol exposure in mice"],"prefix":"10.1016","volume":"49","author":[{"given":"Lindsay","family":"Wieczorek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric W.","family":"Fish","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shonagh K.","family":"O'Leary-Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott E.","family":"Parnell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen K.","family":"Sulik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.alcohol.2015.01.005_bib1","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/j.biopsych.2005.09.008","article-title":"Glucocorticoids and relapse of major depression (dexamethasone\/corticotropin-releasing hormone test in relation to relapse of major depression)","volume":"59","author":"Appelhof","year":"2006","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.alcohol.2015.01.005_bib2","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1176\/ajp.2006.163.6.1061","article-title":"Binge drinking during pregnancy as a predictor of psychiatric disorders on the Structured Clinical Interview for DSM-IV in young adult offspring","volume":"163","author":"Barr","year":"2006","journal-title":"The American Journal of Psychiatry"},{"key":"10.1016\/j.alcohol.2015.01.005_bib3","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/BF00176837","article-title":"Is the forced swimming test a suitable model for revealing antidepressant activity?","volume":"94","author":"Borsini","year":"1988","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.alcohol.2015.01.005_bib4","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/j.psyneuen.2005.02.010","article-title":"Depression and cortisol responses to psychological stress: a meta-analysis","volume":"30","author":"Burke","year":"2005","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.alcohol.2015.01.005_bib5","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.ntt.2005.06.006","article-title":"Behavioral and neurochemical effects on rat offspring after prenatal exposure to ethanol","volume":"27","author":"Carneiro","year":"2005","journal-title":"Neurotoxicology and Teratology"},{"key":"10.1016\/j.alcohol.2015.01.005_bib6","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1001\/archneur.1993.00540070083022","article-title":"Midline cerebral dysgenesis, dysfunction of the hypothalamic-pituitary axis, and fetal alcohol effects","volume":"50","author":"Coulter","year":"1993","journal-title":"Archives of Neurology"},{"key":"10.1016\/j.alcohol.2015.01.005_bib7","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0091-3057(80)90067-2","article-title":"Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines","volume":"13","author":"Crawley","year":"1980","journal-title":"Pharmacology, Biochemistry, and Behavior"},{"key":"10.1016\/j.alcohol.2015.01.005_bib8","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0165-6147(02)02017-5","article-title":"Assessing antidepressant activity in rodents: recent developments and future needs","volume":"23","author":"Cryan","year":"2002","journal-title":"Trends in Pharmacological Sciences"},{"key":"10.1016\/j.alcohol.2015.01.005_bib9","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0306-4530(01)00042-7","article-title":"Developmental traumatology: a contributory mechanism for alcohol and substance use disorders","volume":"27","author":"De Bellis","year":"2002","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.alcohol.2015.01.005_bib10","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.pbb.2006.09.001","article-title":"Effects of prenatal exposure to alcohol on activity, anxiety, motor coordination, and memory in young adult Wistar rats","volume":"85","author":"Dursun","year":"2006","journal-title":"Pharmacology, Biochemistry, and Behavior"},{"key":"10.1016\/j.alcohol.2015.01.005_bib11","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1176\/ajp.155.4.552","article-title":"Mental illness in adults with fetal alcohol syndrome or fetal alcohol effects","volume":"155","author":"Famy","year":"1998","journal-title":"The American Journal of Psychiatry"},{"key":"10.1016\/j.alcohol.2015.01.005_bib12","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0749-3797(99)00059-8","article-title":"Alcohol use prior to pregnancy recognition","volume":"17","author":"Floyd","year":"1999","journal-title":"American Journal of Preventive Medicine"},{"key":"10.1016\/j.alcohol.2015.01.005_bib13","doi-asserted-by":"crossref","first-page":"e733","DOI":"10.1542\/peds.2006-1606","article-title":"Evaluation of psychopathological conditions in children with heavy prenatal alcohol exposure","volume":"119","author":"Fryer","year":"2007","journal-title":"Pediatrics"},{"key":"10.1016\/j.alcohol.2015.01.005_bib14","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/j.1530-0277.2009.01071.x","article-title":"Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 7","volume":"34","author":"Godin","year":"2010","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2015.01.005_bib15","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0306-4530(01)00039-7","article-title":"Early environmental stress and biological vulnerability to drug abuse","volume":"27","author":"Gordon","year":"2002","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.alcohol.2015.01.005_bib16","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1006\/mcne.1993.1044","article-title":"Sexually dimorphic effects of alcohol exposure in utero on neuroendocrine and immune functions in chronic alcohol-exposed adult rats","volume":"4","author":"Halasz","year":"1993","journal-title":"Molecular and Cellular Neuroscience"},{"key":"10.1016\/j.alcohol.2015.01.005_bib17","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1111\/j.1530-0277.2006.00251.x","article-title":"Infant stress reactivity and prenatal alcohol exposure","volume":"30","author":"Haley","year":"2006","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2015.01.005_bib18","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.neubiorev.2009.06.004","article-title":"Prenatal alcohol exposure: fetal programming and later life vulnerability to stress, depression and anxiety disorders","volume":"34","author":"Hellemans","year":"2010","journal-title":"Neuroscience and Biobehavioral Reviews"},{"key":"10.1016\/j.alcohol.2015.01.005_bib19","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1196\/annals.1418.016","article-title":"Prenatal alcohol exposure increases vulnerability to stress and anxiety-like disorders in adulthood","volume":"1144","author":"Hellemans","year":"2008","journal-title":"Annals of the New York Academy of Sciences"},{"key":"10.1016\/j.alcohol.2015.01.005_bib20","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1111\/j.1530-0277.2009.01132.x","article-title":"Prenatal alcohol exposure and chronic mild stress differentially alter depressive- and anxiety-like behaviors in male and female offspring","volume":"34","author":"Hellemans","year":"2010","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2015.01.005_bib21","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1017\/S0954579499002011","article-title":"Effects of prenatal alcohol and cocaine exposure on infant cortisol levels","volume":"11","author":"Jacobson","year":"1999","journal-title":"Development and Psychopathology"},{"key":"10.1016\/j.alcohol.2015.01.005_bib22","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/j.1530-0277.1999.tb04114.x","article-title":"Effects of prenatal ethanol exposure on hypothalamic-pituitary-adrenal responses to chronic cold stress in rats","volume":"23","author":"Kim","year":"1999","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2015.01.005_bib23","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/j.1530-0277.1999.tb04023.x","article-title":"Effects of prenatal exposure to alcohol on the release of adenocorticotropic hormone, corticosterone, and proinflammatory cytokines","volume":"23","author":"Kim","year":"1999","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2015.01.005_bib24","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0736-5748(92)90016-S","article-title":"Patterns of ethanol-induced cell death in the developing nervous system of mice; neural fold states through the time of anterior neural tube closure","volume":"10","author":"Kotch","year":"1992","journal-title":"International Journal of Developmental Neuroscience"},{"key":"10.1016\/j.alcohol.2015.01.005_bib25","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1111\/j.1530-0277.2009.00929.x","article-title":"Effects of prenatal ethanol exposure on hypothalamic-pituitary-adrenal function across the estrous cycle","volume":"33","author":"Lan","year":"2009","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2015.01.005_bib26","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/1044-7431(90)90022-V","article-title":"Effect of prenatal exposure to ethanol on the activity of the hypothalamic-pituitary-adrenal axis of the offspring: importance of the time of exposure to ethanol and possible modulating mechanisms","volume":"1","author":"Lee","year":"1990","journal-title":"Molecular and Cellular Neurosciences"},{"key":"10.1016\/j.alcohol.2015.01.005_bib27","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1007\/s11064-014-1291-5","article-title":"Dihydromyricetin prevents fetal alcohol exposure-induced behavioral and physiological deficits: the roles of GABAA receptors in adolescence","volume":"39","author":"Liang","year":"2014","journal-title":"Neurochemical Research"},{"key":"10.1016\/j.alcohol.2015.01.005_bib28","doi-asserted-by":"crossref","first-page":"e43067","DOI":"10.1371\/journal.pone.0043067","article-title":"Ethanol-induced face-brain dysmorphology patterns are correlative and exposure-stage dependent","volume":"7","author":"Lipinski","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.alcohol.2015.01.005_bib29","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.neubiorev.2006.06.026","article-title":"Early adversity and alcohol availability persistently modify serotonin and hypothalamic-pituitary-adrenal-axis metabolism and related behavior: what experimental research on rodents and primates can tell us","volume":"31","author":"Macr\u00ec","year":"2007","journal-title":"Neuroscience and Biobehavioral Reviews"},{"key":"10.1016\/j.alcohol.2015.01.005_bib30","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/ddrr.68","article-title":"Prevalence and epidemiologic characteristics of FASD from various research methods with an emphasis on recent in-school studies","volume":"15","author":"May","year":"2009","journal-title":"Developmental Disabilities Research Reviews"},{"key":"10.1016\/j.alcohol.2015.01.005_bib31","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1126\/science.6719121","article-title":"Prenatal alcohol exposure alters adult expression of sexually dimorphic behavior in the rat","volume":"224","author":"McGivern","year":"1984","journal-title":"Science"},{"key":"10.1016\/j.alcohol.2015.01.005_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/tera.1420340102","article-title":"Social play in juvenile rats prenatally exposed to alcohol","volume":"34","author":"Meyer","year":"1986","journal-title":"Teratology"},{"key":"10.1016\/j.alcohol.2015.01.005_bib33","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1111\/j.1530-0277.1986.tb05112.x","article-title":"Pituitary-adrenal responses to morphine and footshock stress are enhanced following prenatal alcohol exposure","volume":"10","author":"Nelson","year":"1986","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2015.01.005_bib34","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1126\/science.6334362","article-title":"Elevated concentrations of CSF corticotropin-releasing factor-like immunoreactivity in depressed patients","volume":"226","author":"Nemeroff","year":"1984","journal-title":"Science"},{"key":"10.1016\/j.alcohol.2015.01.005_bib35","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0031-9384(88)90266-1","article-title":"Is immobility of rats in the forced swim test \u201cbehavioral despair\u201d?","volume":"42","author":"Nishimura","year":"1988","journal-title":"Physiology & Behavior"},{"key":"10.1016\/j.alcohol.2015.01.005_bib36","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1111\/j.1530-0277.2000.tb04654.x","article-title":"Prenatal alcohol exposure and depressive features in children","volume":"24","author":"O'Connor","year":"2000","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2015.01.005_bib37","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1081\/ADA-120015880","article-title":"Psychiatric illness in a clinical sample of children with prenatal alcohol exposure","volume":"28","author":"O'Connor","year":"2002","journal-title":"The American Journal of Drug and Alcohol Abuse"},{"key":"10.1016\/j.alcohol.2015.01.005_bib38","first-page":"424","article-title":"Prenatal alcohol exposure results in hyperactivity of the hypothalamic-pituitary-adrenal axis of the offspring: modulation by fostering at birth and postnatal handling","volume":"21","author":"Ogilvie","year":"1997","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2015.01.005_bib39","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1111\/j.1530-0277.1998.tb04312.x","article-title":"Prenatal ethanol exposure differentially alters behavior in males and females on the elevated plus maze","volume":"22","author":"Osborn","year":"1998","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2015.01.005_bib40","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0022-510X(79)90033-9","article-title":"Alcohol embryo- and fetopathy. Neuropathology of 3 children and 3 fetuses","volume":"41","author":"Peiffer","year":"1979","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1016\/j.alcohol.2015.01.005_bib41","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0165-0270(85)90031-7","article-title":"Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat","volume":"14","author":"Pellow","year":"1985","journal-title":"Journal of Neuroscience Methods"},{"key":"10.1016\/j.alcohol.2015.01.005_bib42","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s00213-004-2048-7","article-title":"Forced swimming test in mice: a review of antidepressant activity","volume":"177","author":"Petit-Demouliere","year":"2005","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.alcohol.2015.01.005_bib43","first-page":"185","article-title":"Neurobehavioural outcomes of children with fetal alcohol spectrum disorders: a Canadian perspective","volume":"13","author":"Rasmussen","year":"2008","journal-title":"Paediatrics & Child Health"},{"key":"10.1016\/j.alcohol.2015.01.005_bib44","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s11065-011-9166-x","article-title":"Fetal alcohol spectrum disorders: an overview","volume":"21","author":"Riley","year":"2011","journal-title":"Neuropsychology Review"},{"key":"10.1016\/j.alcohol.2015.01.005_bib45","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.bbr.2013.06.003","article-title":"Early gestational exposure to moderate concentrations of ethanol alters adult behaviour in C57BL\/6J mice","volume":"252","author":"Sanchez Vega","year":"2013","journal-title":"Behavioural Brain Research"},{"key":"10.1016\/j.alcohol.2015.01.005_bib46","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0306-4530(01)00050-6","article-title":"The impact of prenatal stress, fetal alcohol exposure, or both on development: perspectives from a primate model","volume":"27","author":"Schneider","year":"2002","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.alcohol.2015.01.005_bib47","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1176\/ajp.145.11.1391","article-title":"Alcohol consumption, ACTH level, and family history of alcoholism","volume":"145","author":"Schuckit","year":"1988","journal-title":"The American Journal of Psychiatry"},{"key":"10.1016\/j.alcohol.2015.01.005_bib48","doi-asserted-by":"crossref","first-page":"368","DOI":"10.15288\/jsa.1996.57.368","article-title":"Alcohol challenges in young men from alcoholic pedigrees and control families: a report from the COGA project","volume":"57","author":"Schuckit","year":"1996","journal-title":"Journal of Studies on Alcohol"},{"key":"10.1016\/j.alcohol.2015.01.005_bib49","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1586\/ern.09.52","article-title":"Hypothalamic-pituitary-adrenocortical system dysregulation and new treatment strategies in depression","volume":"9","author":"Sch\u00fcle","year":"2009","journal-title":"Expert Review of Neurotherapeutics"},{"key":"10.1016\/j.alcohol.2015.01.005_bib50","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1177\/070674370605100206","article-title":"Prevalence and incidence studies of anxiety disorders: a systematic review of the literature","volume":"51","author":"Somers","year":"2006","journal-title":"Canadian Journal of Psychiatry"},{"key":"10.1016\/j.alcohol.2015.01.005_bib51","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1111\/j.1469-8749.2003.tb00927.x","article-title":"Behavioural phenotype in foetal alcohol syndrome and foetal alcohol effects","volume":"45","author":"Steinhausen","year":"2003","journal-title":"Developmental Medicine and Child Neurology"},{"key":"10.1016\/j.alcohol.2015.01.005_bib52","series-title":"Understanding the occurrence of secondary disabilities in clients with Fetal Alcohol Syndrome (FAS) and Fetal Alcohol Effects (FAE). Final Report to the Centers for Disease Control and Prevention (CDC), August","author":"Streissguth","year":"1996"},{"key":"10.1016\/j.alcohol.2015.01.005_bib53","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1097\/00004703-200408000-00002","article-title":"Risk factors for adverse life outcomes in fetal alcohol syndrome and fetal alcohol effects","volume":"25","author":"Streissguth","year":"2004","journal-title":"Journal of Developmental and Behavioral Pediatrics"},{"key":"10.1016\/j.alcohol.2015.01.005_bib54","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1126\/science.6795717","article-title":"Fetal alcohol syndrome: embryogenesis in a mouse model","volume":"214","author":"Sulik","year":"1981","journal-title":"Science"},{"key":"10.1016\/j.alcohol.2015.01.005_bib55","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0736-5748(84)90014-5","article-title":"Brain malformations in prenatal mice following acute maternal ethanol administration","volume":"2","author":"Sulik","year":"1984","journal-title":"International Journal of Developmental Neuroscience"},{"key":"10.1016\/j.alcohol.2015.01.005_bib56","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/0091-3057(82)90420-8","article-title":"Long-term effects of fetal ethanol exposure on pituitary-adrenal response to stress","volume":"16","author":"Taylor","year":"1982","journal-title":"Pharmacology, Biochemistry, and Behavior"},{"key":"10.1016\/j.alcohol.2015.01.005_bib57","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/j.1530-0277.1985.tb05559.x","article-title":"Effects of in utero exposure to alcohol upon male rats","volume":"9","author":"Udani","year":"1985","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2015.01.005_bib58","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1001\/archgenpsychiatry.2009.50","article-title":"Major depressive disorder and hypothalamic-pituitary-adrenal axis activity: results from a large cohort study","volume":"66","author":"Vreeburg","year":"2009","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.alcohol.2015.01.005_bib59","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1037\/0735-7044.108.6.1188","article-title":"Male and female sexual behavior potential of male rats prenatally exposed to the influence of alcohol, stress, or both factors","volume":"108","author":"Ward","year":"1994","journal-title":"Behavioral Neuroscience"},{"key":"10.1016\/j.alcohol.2015.01.005_bib60","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0741-8329(92)90057-H","article-title":"Prenatal ethanol effects: sex differences in offspring stress responsiveness","volume":"9","author":"Weinberg","year":"1992","journal-title":"Alcohol"},{"key":"10.1016\/j.alcohol.2015.01.005_bib61","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1111\/j.1365-2826.2008.01669.x","article-title":"Prenatal alcohol exposure: foetal programming, the hypothalamic-pituitary-adrenal axis and sex differences in outcome","volume":"20","author":"Weinberg","year":"2008","journal-title":"Journal of Neuroendocrinology"},{"key":"10.1016\/j.alcohol.2015.01.005_bib62","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/j.1530-0277.1996.tb01054.x","article-title":"Fetal ethanol exposure: hypothalamic-pituitary-adrenal and beta-endorphin responses to repeated stress","volume":"20","author":"Weinberg","year":"1996","journal-title":"Alcoholism: Clinical and Experimental Research"},{"key":"10.1016\/j.alcohol.2015.01.005_bib63","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/0278-5846(90)90073-P","article-title":"Neurobehavioral studies of forced swimming: the role of learning and memory in the forced swim test","volume":"14","author":"West","year":"1990","journal-title":"Progress in Neuro-psychopharmacology & Biological Psychiatry"},{"key":"10.1016\/j.alcohol.2015.01.005_bib64","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1038\/sj.mp.4001694","article-title":"Behavioral deficits associated with fetal alcohol exposure are reversed by prenatal thyroid hormone treatment: a role for maternal thyroid hormone deficiency in FAE","volume":"10","author":"Wilcoxon","year":"2005","journal-title":"Molecular Psychiatry"},{"key":"10.1016\/j.alcohol.2015.01.005_bib65","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1111\/j.1755-5949.2010.00207.x","article-title":"HPA axis alterations in mental disorders: impact on memory and its relevance for therapeutic interventions","volume":"17","author":"Wingenfeld","year":"2011","journal-title":"CNS Neuroscience & Therapeutics"},{"key":"10.1016\/j.alcohol.2015.01.005_bib66","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.biopsych.2004.03.017","article-title":"Effect of comorbid anxiety disorders on the hypothalamic-pituitary-adrenal axis response to a social stressor in major depression","volume":"56","author":"Young","year":"2004","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.alcohol.2015.01.005_bib67","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0022-3956(01)00013-9","article-title":"Cortisol response in the combined dexamethasone\/CRH test as predictor of relapse in patients with remitted depression. a prospective study","volume":"35","author":"Zobel","year":"2001","journal-title":"Journal of Psychiatric Research"}],"container-title":["Alcohol"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741832914202199?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741832914202199?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,20]],"date-time":"2019-08-20T04:12:51Z","timestamp":1566274371000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0741832914202199"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5]]},"references-count":67,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["S0741832914202199"],"URL":"https:\/\/doi.org\/10.1016\/j.alcohol.2015.01.005","relation":{},"ISSN":["0741-8329"],"issn-type":[{"value":"0741-8329","type":"print"}],"subject":[],"published":{"date-parts":[[2015,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypothalamic-pituitary-adrenal axis and behavioral dysfunction following early binge-like prenatal alcohol exposure in mice","name":"articletitle","label":"Article Title"},{"value":"Alcohol","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.alcohol.2015.01.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}