{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T00:59:35Z","timestamp":1780880375737,"version":"3.54.1"},"reference-count":33,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T00:00:00Z","timestamp":1722297600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Allergology International"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.alit.2024.06.003","type":"journal-article","created":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T15:51:52Z","timestamp":1726933912000},"page":"72-77","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Dysbiosis of the human skin mycobiome in patients receiving systemic IL-23 inhibitors"],"prefix":"10.1016","volume":"74","author":[{"given":"Yuta","family":"Koike","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayaka","family":"Kuwatsuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Motooka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Murota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.alit.2024.06.003_bib1","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1126\/science.1260144","article-title":"Dialogue between skin microbiota and immunity","volume":"346","author":"Belkaid","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.alit.2024.06.003_bib2","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1038\/nrmicro2537","article-title":"The skin microbiome","volume":"9","author":"Grice","year":"2011","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.alit.2024.06.003_bib3","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.alit.2021.11.001","article-title":"Skin microbiome of atopic dermatitis","volume":"71","author":"Koh","year":"2022","journal-title":"Allergol Int"},{"key":"10.1016\/j.alit.2024.06.003_bib4","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/nature12171","article-title":"Topographic diversity of fungal and bacterial communities in human skin","volume":"498","author":"Findley","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.alit.2024.06.003_bib5","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/1346-8138.12739","article-title":"Molecular characterization of the skin fungal microbiome in patients with psoriasis","volume":"42","author":"Takemoto","year":"2015","journal-title":"J\u00a0Dermatol"},{"key":"10.1016\/j.alit.2024.06.003_bib6","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1111\/exd.13500","article-title":"Analysis of the skin mycobiome in adult patients with atopic dermatitis","volume":"27","author":"Han","year":"2018","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.alit.2024.06.003_bib7","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1111\/exd.14450","article-title":"Skin microbiome alterations in seborrheic dermatitis and dandruff: a systematic review","volume":"30","author":"Tao","year":"2021","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.alit.2024.06.003_bib8","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1111\/jdv.18347","article-title":"Dysbiosis of skin microbiota with increased fungal diversity is associated with severity of disease in atopic dermatitis","volume":"36","author":"Schmid","year":"2022","journal-title":"J\u00a0Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.alit.2024.06.003_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.mib.2023.102381","article-title":"The skin mycobiome and intermicrobial interactions in the cutaneous niche","volume":"76","author":"Tuor","year":"2023","journal-title":"Curr Opin Microbiol"},{"key":"10.1016\/j.alit.2024.06.003_bib10","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.4049\/jimmunol.1800013","article-title":"Discovery of the IL-23\/IL-17 signaling pathway and the treatment of psoriasis","volume":"201","author":"Hawkes","year":"2018","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.alit.2024.06.003_bib11","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/1346-8138.14096","article-title":"Safety of biologics in psoriasis","volume":"45","author":"Kamata","year":"2018","journal-title":"J\u00a0Dermatol"},{"key":"10.1016\/j.alit.2024.06.003_bib12","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1111\/1346-8138.15156","article-title":"Mycobacterium tuberculosis infection in psoriatic patients treated with biologics: real-world data from 18 Japanese facilities","volume":"47","author":"Kaneko","year":"2020","journal-title":"J\u00a0Dermatol"},{"key":"10.1016\/j.alit.2024.06.003_bib13","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1001\/jamadermatol.2021.2599","article-title":"Association between biologics use and risk of serious infection in patients with psoriasis","volume":"157","author":"Penso","year":"2021","journal-title":"JAMA Dermatol"},{"key":"10.1016\/j.alit.2024.06.003_bib14","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1056\/NEJMoa1503824","article-title":"Phase 3 studies comparing brodalumab with ustekinumab in psoriasis","volume":"373","author":"Lebwohl","year":"2015","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.alit.2024.06.003_bib15","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1056\/NEJMoa1512711","article-title":"Phase 3 trials of ixekizumab in moderate-to-severe plaque psoriasis","volume":"375","author":"Gordon","year":"2016","journal-title":"N Engl J Med"},{"key":"10.1016\/j.alit.2024.06.003_bib16","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.jaad.2016.03.024","article-title":"Secukinumab long-term safety experience: a pooled analysis of 10 phase II and III clinical studies in patients with moderate to severe plaque psoriasis","volume":"75","author":"van de Kerkhof","year":"2016","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.alit.2024.06.003_bib17","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.1016\/j.jid.2018.03.1501","article-title":"Longitudinal study of the psoriasis-associated skin microbiome during therapy with ustekinumab in a randomized phase 3b clinical trial","volume":"138","author":"Loesche","year":"2018","journal-title":"J\u00a0Investig Dermatol"},{"key":"10.1016\/j.alit.2024.06.003_bib18","doi-asserted-by":"crossref","first-page":"3892","DOI":"10.3390\/ijms21113892","article-title":"Skin mycobiome of psoriasis patients is retained during treatment with TNF and IL-17 inhibitors","volume":"21","author":"Koike","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.alit.2024.06.003_bib19","doi-asserted-by":"crossref","first-page":"238","DOI":"10.3389\/fmicb.2017.00238","article-title":"Fungal ITS1 deep-sequencing strategies to reconstruct the composition of a 26-species community and evaluation of the gut mycobiota of healthy Japanese individuals","volume":"8","author":"Motooka","year":"2017","journal-title":"Front Microbiol"},{"key":"10.1016\/j.alit.2024.06.003_bib20","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1038\/s41587-019-0209-9","article-title":"Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2","volume":"37","author":"Bolyen","year":"2019","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.alit.2024.06.003_bib21","article-title":"Cutaneous Malassezia: commensal, pathogen, or protector?","volume":"10","author":"Vijaya Chandra","year":"2020","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.alit.2024.06.003_bib22","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/myc.13402","article-title":"Dysbiosis of skin mycobiome in atopic dermatitis","volume":"65","author":"Tao","year":"2022","journal-title":"Mycoses"},{"key":"10.1016\/j.alit.2024.06.003_bib23","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.chom.2019.02.002","article-title":"The skin commensal yeast Malassezia triggers a type 17 response that coordinates anti-fungal immunity and exacerbates skin inflammation","volume":"25","author":"Sparber","year":"2019","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.alit.2024.06.003_bib24","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1080\/14712598.2020.1727439","article-title":"Clinical and histopathological characterization of eczematous eruptions occurring in course of anti IL-17 treatment: a case series and review of the literature","volume":"20","author":"Caldarola","year":"2020","journal-title":"Expert Opin Biol Ther"},{"key":"10.1016\/j.alit.2024.06.003_bib25","doi-asserted-by":"crossref","first-page":"e173","DOI":"10.1111\/1346-8138.16308","article-title":"Treatment with an interleukin-17 inhibitor resulted in complete remission of psoriasis and flare-up of atopic dermatitis","volume":"49","author":"Hattori","year":"2022","journal-title":"J\u00a0Dermatol"},{"key":"10.1016\/j.alit.2024.06.003_bib26","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/1346-8138.16586","article-title":"Skin microbiome analysis in a case of atopic dermatitis induced by an interleukin 17 inhibitor used to treat psoriasis","volume":"50","author":"Hattori","year":"2023","journal-title":"J\u00a0Dermatol"},{"key":"10.1016\/j.alit.2024.06.003_bib27","doi-asserted-by":"crossref","first-page":"7297","DOI":"10.4049\/jimmunol.0904180","article-title":"Analysis of complex biomarkers for human immune-mediated disorders based on cytokine responsiveness of peripheral blood cells","volume":"184","author":"Davis","year":"2010","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.alit.2024.06.003_bib28","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1001\/jamadermatol.2023.4846","article-title":"Risk of paradoxical eczema in patients receiving biologics for psoriasis","volume":"160","author":"Al-Janabi","year":"2024","journal-title":"JAMA Dermatol"},{"key":"10.1016\/j.alit.2024.06.003_bib29","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/prd.12378","article-title":"Fungal diseases: oral dysbiosis in susceptible hosts","volume":"87","author":"Villar","year":"2021","journal-title":"Periodontology 2000"},{"key":"10.1016\/j.alit.2024.06.003_bib30","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s40257-020-00578-0","article-title":"Use of IL-23 inhibitors for the treatment of plaque psoriasis and psoriatic arthritis: a comprehensive review","volume":"22","author":"Yang","year":"2021","journal-title":"Am J Clin Dermatol"},{"key":"10.1016\/j.alit.2024.06.003_bib31","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1186\/s40168-018-0533-1","article-title":"Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization","volume":"6","author":"Chang","year":"2018","journal-title":"Microbiome"},{"key":"10.1016\/j.alit.2024.06.003_bib32","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.jid.2016.10.033","article-title":"Performing skin microbiome research: a method to the madness","volume":"137","author":"Kong","year":"2017","journal-title":"J\u00a0Investig Dermatol"},{"key":"10.1016\/j.alit.2024.06.003_bib33","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1101\/gr.075549.107","article-title":"A\u00a0diversity profile of the human skin microbiota","volume":"18","author":"Grice","year":"2008","journal-title":"Genome Res"}],"container-title":["Allergology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1323893024000807?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1323893024000807?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T16:41:55Z","timestamp":1747240915000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1323893024000807"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["S1323893024000807"],"URL":"https:\/\/doi.org\/10.1016\/j.alit.2024.06.003","relation":{},"ISSN":["1323-8930"],"issn-type":[{"value":"1323-8930","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dysbiosis of the human skin mycobiome in patients receiving systemic IL-23 inhibitors","name":"articletitle","label":"Article Title"},{"value":"Allergology International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.alit.2024.06.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Japanese Society of Allergology. Published by Elsevier B.V\u00e9","name":"copyright","label":"Copyright"}]}}